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A 6-year experience with urine drug testing by family service agencies in Nova Scotia, Canada.

https://arctichealth.org/en/permalink/ahliterature193186
Source
Forensic Sci Int. 2001 Oct 1;121(3):151-6
Publication Type
Article
Date
Oct-1-2001
Author
A D Fraser
Author Affiliation
Clinical & Forensic Toxicologist, Queen Elizabeth II Health Sciences Centre, Dalhousie University, 1278 Tower Road, Halifax, NS, Canada B3H 2Y9. adfraser@is.dal.ca
Source
Forensic Sci Int. 2001 Oct 1;121(3):151-6
Date
Oct-1-2001
Language
English
Publication Type
Article
Keywords
Adult
Child
Child Custody
Chromatography, High Pressure Liquid
Humans
Nova Scotia - epidemiology
Questionnaires
Social Work
Substance-Related Disorders - epidemiology - urine
Abstract
The objective of this study is to describe a urine drug-testing program implemented for parents with a history of substance abuse by family service agencies in the province of Nova Scotia, Canada. Nurse collectors went to the parents' home to obtain urine specimens under direct observation and then delivered the specimens to the toxicology laboratory or arranged shipment by courier under chain of custody. Each urine specimen was screened for cannabinoids, cocaine metabolite, opiates, amphetamines and benzodiazepines, ethyl alcohol and creatinine. All positive screening tests were confirmed by another method such as gas chromatography-mass spectrometry (GC-MS). In 15,979 urine specimens collected from 1994 to 1999, the percent positive rate for one (or more) drugs/metabolites ranged from 45.6% (1994-1996) to 30.0% (1998, 1999). A total of 575 specimens (3.7%) were dilute (urine creatinine
PubMed ID
11566417 View in PubMed
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A 10-year population-based study of uterine rupture.

https://arctichealth.org/en/permalink/ahliterature188134
Source
Obstet Gynecol. 2002 Oct;100(4):749-53
Publication Type
Article
Date
Oct-2002
Author
Katharina E Kieser
Thomas F Baskett
Author Affiliation
Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, Nova Scotia, Canada.
Source
Obstet Gynecol. 2002 Oct;100(4):749-53
Date
Oct-2002
Language
English
Publication Type
Article
Keywords
Adult
Asphyxia Neonatorum - epidemiology
Blood Transfusion
Female
Humans
Incidence
Infant, Newborn
Nova Scotia - epidemiology
Pregnancy
Risk factors
Uterine Rupture - epidemiology - mortality
Vaginal Birth after Cesarean
Abstract
To review the incidence, associated factors, methods of diagnosis, and maternal and perinatal morbidity and mortality associated with uterine rupture in one Canadian province.
Using a perinatal database, all cases of uterine rupture in the province of Nova Scotia for the 10-year period 1988-1997 were identified and the maternal and perinatal mortality and morbidity reviewed in detail.
Over the 10 years, there were 114,933 deliveries with 39 cases of uterine rupture: 18 complete and 21 incomplete (dehiscence). Thirty-six women had a previous cesarean delivery: 33 low transverse, two classic, one low vertical. Of the 114,933 deliveries, 11,585 (10%) were in women with a previous cesarean delivery. Uterine rupture in those undergoing a trial for vaginal delivery (4516) was complete rupture in 2.4 per 1000 and dehiscence in 2.4 per 1000. There were no maternal deaths, and maternal morbidity was low in patients with dehiscence. In comparison, 44% of those with complete uterine rupture received blood transfusion (odds ratio 7.60, 95% confidence interval 1.14, 82.14, P =.025). Two perinatal deaths were attributable to complete uterine rupture, one after previous cesarean delivery. Compared with dehiscence, infants born after uterine rupture had significantly lower 5-minute Apgar scores (P
PubMed ID
12383544 View in PubMed
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229 people, 15,000 body parts: pathologists help solve Swissair 111's grisly puzzles.

https://arctichealth.org/en/permalink/ahliterature203179
Source
CMAJ. 1999 Jan 26;160(2):241-3
Publication Type
Article
Date
Jan-26-1999
Author
N. Robb
Source
CMAJ. 1999 Jan 26;160(2):241-3
Date
Jan-26-1999
Language
English
Publication Type
Article
Keywords
Accidents, Aviation
Attitude of Health Personnel
Coroners and Medical Examiners - psychology
DNA Fingerprinting
Family - psychology
Grief
Humans
Nova Scotia
Professional-Family Relations
Abstract
Only 1 of the 229 passengers and crew members killed when Swissair Flight 111 crashed off Nova Scotia in September was visually identifiable. Identifying everyone else on board involved medical and dental detective work of the first order.
PubMed ID
9951448 View in PubMed
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Absence of serotype-specific surface antigen and altered teichoic acid glycosylation among epidemic-associated strains of Listeria monocytogenes.

https://arctichealth.org/en/permalink/ahliterature197060
Source
J Clin Microbiol. 2000 Oct;38(10):3856-9
Publication Type
Article
Date
Oct-2000
Author
E E Clark
I. Wesley
F. Fiedler
N. Promadej
S. Kathariou
Author Affiliation
Department of Microbiology, University of Hawaii, Honolulu, Hawaii 96822, USA.
Source
J Clin Microbiol. 2000 Oct;38(10):3856-9
Date
Oct-2000
Language
English
Publication Type
Article
Keywords
Antibodies, Monoclonal
Antigens, Bacterial - analysis
Antigens, Surface - analysis
Cheese - microbiology
Disease Outbreaks
Female
Food Microbiology
Glycosylation
Humans
Listeria monocytogenes - classification - isolation & purification
Listeriosis - epidemiology - microbiology - transmission
Mexico - epidemiology
New England - epidemiology
Nova Scotia - epidemiology
Pregnancy
Serotyping
Teichoic Acids - analysis - chemistry
Abstract
Outbreaks of food-borne listeriosis have often involved strains of serotype 4b. Examination of multiple isolates from three different outbreaks revealed that ca. 11 to 29% of each epidemic population consisted of strains which were negative with the serotype-specific monoclonal antibody c74.22, lacked galactose from the teichoic acid of the cell wall, and were resistant to the serotype 4b-specific phage 2671.
Notes
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PubMed ID
11015420 View in PubMed
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Access to care and satisfaction in colorectal cancer patients.

https://arctichealth.org/en/permalink/ahliterature172325
Source
World J Surg. 2005 Nov;29(11):1444-51
Publication Type
Article
Date
Nov-2005
Author
Geoffrey A Porter
Karen M Inglis
Lori A Wood
Paul J Veugelers
Author Affiliation
Department of Surgery, Dalhousie University, 7-007 Victoria Building, QEII Health Sciences Center, 1278 Tower Road, Halifax, Nova Scotia B3H 2Y9, Canada. Geoff.Porter@dal.ca
Source
World J Surg. 2005 Nov;29(11):1444-51
Date
Nov-2005
Language
English
Publication Type
Article
Keywords
Aged
Colorectal Neoplasms - diagnosis - surgery
Female
Health Services Accessibility
Humans
Male
Multivariate Analysis
Nova Scotia
Patient satisfaction
Prospective Studies
Waiting Lists
Abstract
This study described the various components of access to care for resectable colorectal cancer, and correlated the timeliness of these components with patient satisfaction. With a prospective/retrospective cohort design, all patients undergoing surgical resection for primary colorectal cancer from 2/1/01 to 15/12/01, were identified during their admission for surgery. A comprehensive, standardized method of ascertaining specific time intervals, which included a patient interview, was used. A patient satisfaction questionnaire was developed, tested, and used in consenting patients. Over the study period, 118 patients underwent colorectal cancer resection. Of these, 110 (93%) consented to participate and 101 (86%) completed the satisfaction questionnaire, including test-retest. The median time intervals (interquartile range) for the various components of access to care were as follows: symptoms to first physician visit, 32 days (10-75); first physician visit to diagnosis, 88 days (44-218); diagnosis to surgery, 19 days (10-44); surgery to chemotherapy (where applicable), 54 days (47-72). On multivariate analysis, tumor location in the rectum was associated with longer prediagnosis intervals, whereas increasing tumor stage was associated with shorter intervals from diagnosis to surgery. Variation in the time interval from diagnosis to surgery was associated with patient satisfaction (r = 0.49; P
PubMed ID
16240060 View in PubMed
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Access to confidential sexual health services.

https://arctichealth.org/en/permalink/ahliterature167386
Source
Can Nurse. 2006 Sep;102(7):29-31
Publication Type
Article
Date
Sep-2006
Author
Evelyn P Kennedy
Cyndee MacPhee
Author Affiliation
St. Francis Xavier University/Cape Breton University Nursing Program, Sydney, Nova Scotia.
Source
Can Nurse. 2006 Sep;102(7):29-31
Date
Sep-2006
Language
English
Publication Type
Article
Keywords
Adolescent
Adolescent Health Services
Confidentiality
Female
Health Services Accessibility
Health services needs and demand
Humans
Interviews as Topic
Nova Scotia
Sexuality
Abstract
The authors conducted one-on-one interviews with adolescent females, aged 13 to 16, concerning their perception of the confidentiality of sexual health services available to them. Participants were selected from an urban school with a youth health centre (YHC) and also from a rural school without access to a YHC. They typically viewed traditional health services as not confidential and reported concern about disclosure to parents. This qualitative study suggests that adolescent females have an absolute need to maintain positive parental regard by preventing disclosure of sexual activity.
PubMed ID
16989098 View in PubMed
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The accuracy of administrative data diagnoses of systemic autoimmune rheumatic diseases.

https://arctichealth.org/en/permalink/ahliterature134892
Source
J Rheumatol. 2011 Aug;38(8):1612-6
Publication Type
Article
Date
Aug-2011
Author
Sasha Bernatsky
Tina Linehan
John G Hanly
Author Affiliation
Division of Clinical Epidemiology, Department of Medicine, McGill University Health Centre (MUHC), Montreal, Quebec, Canada. sasha.bernatsky@mail.mcgill.ca
Source
J Rheumatol. 2011 Aug;38(8):1612-6
Date
Aug-2011
Language
English
Publication Type
Article
Keywords
Autoimmune Diseases - diagnosis - immunology
Databases, Factual - standards
Hospital Administration - standards
Humans
Nova Scotia
Organization and Administration - standards
Reproducibility of Results
Rheumatic Diseases - diagnosis - immunology
Sensitivity and specificity
Abstract
To examine the validity of case definitions for systemic autoimmune rheumatic diseases [SARD; systemic lupus erythematosus (SLE), systemic sclerosis (SSc), myositis, Sjögren's syndrome, vasculitis, and polymyalgia rheumatica] based on administrative data, compared to rheumatology records.
A list of rheumatic disease diagnoses was generated from population-based administrative billing and hospitalization databases. Subjects who had been seen by an arthritis center rheumatologist were identified, and the medical records reviewed.
We found that 844 Nova Scotia residents had a diagnosis of one of the rheumatic diseases of interest, based on administrative data, and had had = 1 rheumatology assessment at a provincial arthritis center. Charts were available on 824 subjects, some of whom had been identified in the administrative database with > 1 diagnosis. Thus a total of 1136 diagnoses were available for verification against clinical records. Of the 824 subjects, 680 (83%) had their administrative database diagnoses confirmed on chart review. The majority of subjects who were "false-positive" for a given rheumatic disease on administrative data had a true diagnosis of a similar rheumatic disease. Most sensitivity estimates for specific administrative data-based case definitions were > 90%, although for SSc, the sensitivity was 80.5%. The specificity estimates were also > 90%, except for SLE, where the specificity was 72.5%.
Although health administrative data may be a valid resource, there are potential problems regarding the specificity and sensitivity of case definitions, which should be kept in mind for future studies.
PubMed ID
21532057 View in PubMed
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The accuracy of outcome prediction models for childhood-onset epilepsy.

https://arctichealth.org/en/permalink/ahliterature173004
Source
Epilepsia. 2005 Sep;46(9):1526-32
Publication Type
Article
Date
Sep-2005
Author
Miranda Geelhoed
Anne Olde Boerrigter
Peter Camfield
Ada T Geerts
Willem Arts
Bruce Smith
Carol Camfield
Author Affiliation
Department of Pediatric Neurology, Erasmus MC, Sophia Children's Hospital, Rotterdam, The Netherlands.
Source
Epilepsia. 2005 Sep;46(9):1526-32
Date
Sep-2005
Language
English
Publication Type
Article
Keywords
Age of Onset
Anticonvulsants - therapeutic use
Child
Child, Preschool
Cohort Studies
Electroencephalography - statistics & numerical data
Epilepsy - classification - diagnosis - drug therapy
Female
Follow-Up Studies
Humans
Intelligence Tests - statistics & numerical data
Logistic Models
Male
Models, Statistical
Netherlands
Nova Scotia
Outcome Assessment (Health Care)
Prognosis
Prospective Studies
Abstract
Two large prospective cohort studies of childhood epilepsy (Nova Scotia and the Netherlands) each developed a statistical model to predict long-term outcome. We sought to evaluate the accuracy of a prognostic model based on the two studies combined.
Analyses with classification tree models and stepwise logistic regression produced predictive models for the combined dataset and the two separate cohorts. The resulting models were then externally validated on the opposite cohort. Remission was defined as no longer receiving daily medication for any length of time at the end of follow-up.
The combined cohorts yielded 1,055 evaluable patients. At the end of follow-up (>or=5 years in >96%), 622 (59%) were in remission. By using the combined data, the classification tree model and the logistic regression model predicted the outcome correctly in approximately 70%. The classification tree model split the data on epilepsy type and age at first seizure. Predictors in the logistic regression model were: seizure number before treatment, age at first seizure, absence seizures, epilepsy types of symptomatic generalized and symptomatic partial, preexisting neurologic signs, intelligence, and the combination of febrile seizures and cryptogenic partial epilepsy. When the prediction models from each cohort were cross-validated on the opposite cohort, the outcome was predicted slightly less accurately than did the model from the combined data.
Based on currently available clinical and EEG variables, predicting the outcome of childhood epilepsy may be difficult and appears to be incorrect in about one of every three patients.
PubMed ID
16146449 View in PubMed
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1332 records – page 1 of 134.