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294 records – page 1 of 30.

Agreement on disease-specific criteria for do-not-resuscitate orders in acute stroke. Members of the Canadian and Western New York Stroke Consortiums.

https://arctichealth.org/en/permalink/ahliterature212814
Source
Stroke. 1996 Feb;27(2):232-7
Publication Type
Article
Date
Feb-1996
Author
A V Alexandrov
P M Pullicino
E M Meslin
J W Norris
Author Affiliation
Department of Neurology, Buffalo General Hospital, State University of New York, USA.
Source
Stroke. 1996 Feb;27(2):232-7
Date
Feb-1996
Language
English
Publication Type
Article
Keywords
Acute Disease
Brain Damage, Chronic
Brain diseases
Canada
Cerebrovascular Disorders - mortality - nursing - physiopathology
Consensus
Ethics, Medical
Ethics, Nursing
Guidelines as Topic
Humans
New York
Patient care team
Patient Selection
Physicians
Professional-Family Relations
Prognosis
Resuscitation Orders
Withholding Treatment
Abstract
The do-not-resuscitate (DNR) order is a mechanism of withholding cardiopulmonary resuscitation (CPR). The lack of DNR guidelines specific for acute stroke may result in many stroke patients receiving unnecessary and futile resuscitation and ventilator-assisted breathing.
A prospective multicenter evaluation of disease-specific criteria for DNR orders in acute stroke was initiated using a modified Delphi process. The participants were the Canadian and Western New York Stroke Consortium members who are closely involved in caring for acute stroke patients and conducting clinical trials at the academic centers. Previously published provisional criteria were reviewed by the participants. Modifications were made to the criteria until statistically significant agreement (P
PubMed ID
8571415 View in PubMed
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AIDS management: five hospitals compared.

https://arctichealth.org/en/permalink/ahliterature230659
Source
Dimens Health Serv. 1989 Jun;66(5):14-7, 28-30
Publication Type
Article
Date
Jun-1989

[AIDS--prevention we can start to learn from]

https://arctichealth.org/en/permalink/ahliterature8646
Source
Sygeplejersken. 1988 Feb 24;88(8):20-4
Publication Type
Article
Date
Feb-24-1988

Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.

https://arctichealth.org/en/permalink/ahliterature153695
Source
Hum Hered. 2009;67(3):193-205
Publication Type
Article
Date
2009
Author
Wendy K Chung
Amit Patki
Naoki Matsuoka
Bert B Boyer
Nianjun Liu
Solomon K Musani
Anna V Goropashnaya
Perciliz L Tan
Nicholas Katsanis
Stephen B Johnson
Peter K Gregersen
David B Allison
Rudolph L Leibel
Hemant K Tiwari
Author Affiliation
Columbia University Medical Center, New York, NY 10032, USA. wkc15@columbia.edu
Source
Hum Hered. 2009;67(3):193-205
Date
2009
Language
English
Publication Type
Article
Keywords
Adiposity - genetics
Adult
Alaska
Body Composition - genetics
Body mass index
Epistasis, Genetic
European Continental Ancestry Group - genetics
Female
Ghrelin - genetics
Haplotypes
Humans
Inuits - genetics
Male
Middle Aged
New York City
Phenotype
Polymorphism, Single Nucleotide
Sequence Analysis, DNA
Skinfold thickness
Waist Circumference - genetics
Abstract
Human adiposity is highly heritable, but few of the genes that predispose to obesity in most humans are known. We tested candidate genes in pathways related to food intake and energy expenditure for association with measures of adiposity.
We studied 355 genetic variants in 30 candidate genes in 7 molecular pathways related to obesity in two groups of adult subjects: 1,982 unrelated European Americans living in the New York metropolitan area drawn from the extremes of their body mass index (BMI) distribution and 593 related Yup'ik Eskimos living in rural Alaska characterized for BMI, body composition, waist circumference, and skin fold thicknesses. Data were analyzed by using a mixed model in conjunction with a false discovery rate (FDR) procedure to correct for multiple testing.
After correcting for multiple testing, two single nucleotide polymorphisms (SNPs) in Ghrelin (GHRL) (rs35682 and rs35683) were associated with BMI in the New York European Americans. This association was not replicated in the Yup'ik participants. There was no evidence for gene x gene interactions among genes within the same molecular pathway after adjusting for multiple testing via FDR control procedure.
Genetic variation in GHRL may have a modest impact on BMI in European Americans.
Notes
Cites: Int J Circumpolar Health. 2005 Jun;64(3):281-9016050322
Cites: N Engl J Med. 1999 Oct 7;341(15):1097-10510511607
Cites: J Clin Endocrinol Metab. 2005 Dec;90(12):6672-716204371
Cites: J Pediatr Endocrinol Metab. 2005 Nov;18(11):1083-616459454
Cites: Obesity (Silver Spring). 2006 Apr;14(4):529-64416741264
Cites: Diabet Med. 2006 Jun;23(6):685-916759313
Cites: Metabolism. 2006 Oct;55(10):1420-516979415
Cites: Int J Obes (Lond). 2006 Nov;30(11):1609-1416865101
Cites: Annu Rev Genomics Hum Genet. 2006;7:125-4816722803
Cites: Hum Mutat. 2007 Mar;28(3):294-30217072869
Cites: Am J Clin Nutr. 2007 Jul;86(1):25-3217616759
Cites: Neurosci Biobehav Rev. 2002 Jun;26(4):393-42812204189
Cites: JAMA. 2002 Oct 9;288(14):1723-712365955
Cites: Neuron. 2002 Oct 10;36(2):199-21112383777
Cites: Hum Hered. 2003;55(1):56-6512890927
Cites: Biometrics. 2003 Jun;59(2):420-912926727
Cites: Int J Obes Relat Metab Disord. 2004 Mar;28(3):447-5014724664
Cites: J Urban Health. 2004 Jun;81(2):301-1015136663
Cites: JAMA. 2004 Jun 16;291(23):2847-5015199035
Cites: Trends Mol Med. 2001 May;7(5):205-1311325632
Cites: Am J Hum Genet. 2002 Feb;70(2):425-3411791212
Cites: Genet Med. 2002 Mar-Apr;4(2):45-6111882781
Cites: J Clin Endocrinol Metab. 2002 Jun;87(6):271612050239
Cites: Biotechniques. 2002 Jun;Suppl:56-8, 60-112083399
Cites: Am J Hum Genet. 2004 Oct;75(4):561-7015290652
Cites: Eur J Endocrinol. 2004 Jul;151(1):127-3315248833
Cites: Obes Res. 2002 Aug;10(8):782-9112181387
Cites: JAMA. 1986 Jul 4;256(1):51-43712713
Cites: N Engl J Med. 1990 May 24;322(21):1483-72336075
Cites: Int J Obes Relat Metab Disord. 1996 Nov;20(11):990-98923155
Cites: Am J Hum Genet. 1998 Oct;63(4):1190-2019758596
Cites: Endocr Rev. 1999 Feb;20(1):68-10010047974
Cites: Trends Endocrinol Metab. 2005 Aug;16(6):267-7216005242
PubMed ID
19077438 View in PubMed
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Analysis of the Toronto-Rochester Depression Study follow-up data confirms an HLA-region gene contribution to susceptibility to affective disorder.

https://arctichealth.org/en/permalink/ahliterature231953
Source
Genet Epidemiol. 1989;6(1):305-10
Publication Type
Article
Date
1989
Author
L R Weitkamp
H C Stancer
Author Affiliation
Department of Psychiatry, University of Rochester Medical Center, New York 14642.
Source
Genet Epidemiol. 1989;6(1):305-10
Date
1989
Language
English
Publication Type
Article
Keywords
Affective Disorders, Psychotic - diagnosis - genetics
Canada
Disease Susceptibility
Follow-Up Studies
Gene Frequency
Genes, MHC Class II
HLA Antigens - genetics
Haplotypes
Humans
New York
Abstract
Analysis of HLA haplotype distributions in relation to major affective disorder in affected sibling pairs and affected aunt or uncle and niece or nephew pairs confirmed that HLA-region genes do contribute to susceptibility to affective disorder. The data indicated that this effect may be greater in unipolar than in bipolar disorder, and more apparent in families with few affected members than in heavily loaded families. Nonrandom assortment of HLA haplotypes to affected and unaffected offspring in "low load" families occurred principally for the haplotype transmitted from the side of the family without affective disorder. We conclude that HLA-region genes contribute to but are not the only factor in susceptibility to major depression.
PubMed ID
2499504 View in PubMed
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Angina pectoris in presumably healthy middle-aged men. Validation of two questionnaire methods in making the diagnosis of angina pectoris.

https://arctichealth.org/en/permalink/ahliterature50449
Source
Eur J Cardiol. 1977 Dec;6(4):285-98
Publication Type
Article
Date
Dec-1977
Author
J. Erikssen
K. Forfang
O. Storstein
Source
Eur J Cardiol. 1977 Dec;6(4):285-98
Date
Dec-1977
Language
English
Publication Type
Article
Keywords
Adult
Angina Pectoris - diagnosis - epidemiology
Angiocardiography
Comparative Study
Exercise Test
Follow-Up Studies
Health Maintenance Organizations
Humans
Male
Methods
Middle Aged
New York City
Norway
Questionnaires
Risk
World Health Organization
Abstract
In 2014 presumably healthy men aged 40-59 yr the prevalence of previously undiagnosed angina pectoris was assessed by two angina questionnaires: (1) World Health Organization Questionnaire (WHO-Q) and (2) Greater New York Health Insurance Plan Survey Questionnaire (NY-Q). The angina prevalence given by the questionnaires singly or in combination varied between 1.15 and 4.7% (lowest prevalence by the WHO-Q interview version (WHO-Qi) and highest by the WHO-Q self-administered version and the NY-Q in combination), indicating a considerable variation in prevalence with variation in criteria used. Validation of the questionnaires by means of (1) coronary angiography, and (2) follow-up in selected cases, indicated NY-Q superiority over WHO-Q in predicting the presence of coronary heart disease (CHD). WHO-Qi had a particularly low sensitivity without being more specific. However, CHD-risk factor patterns in subgroups of individuals classified as angina-positive or -negative by the respective questionnaires were similar.
PubMed ID
590299 View in PubMed
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Source
Ter Arkh. 1995;67(8):23-5
Publication Type
Article
Date
1995
Author
A P Iurenev
R. Devereux
E E Rynskova
P B Dubov
Source
Ter Arkh. 1995;67(8):23-5
Date
1995
Language
Russian
Publication Type
Article
Keywords
Cardiovascular Diseases - diagnosis - etiology
Chordae Tendineae - abnormalities - ultrasonography
Echocardiography
Electrocardiography, Ambulatory
Exercise Test
Humans
Moscow
New York
Retrospective Studies
Abstract
ECG of 322 patients with various cardiovascular diseases allowed the conclusion on the occurrence of anomalous chordae of the heart in 21.7% of cases. The chordae had no effect on the disease diagnosis, running, hemodynamics, left ventricular myocardial mass.
PubMed ID
7482325 View in PubMed
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294 records – page 1 of 30.