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1146 records – page 1 of 115.

19th Anglo-Danish-Dutch Diabetes Group meeting.

https://arctichealth.org/en/permalink/ahliterature47563
Source
Diabet Med. 2002 Mar;19(3):259
Publication Type
Conference/Meeting Material
Date
Mar-2002
Author
E J P de Koning
T. Vilsboll
F. Dela
Author Affiliation
Department of Internal Medicine, Section of Vascular Medicine, Diabetes and Endocrinology, University Medical Centre Utrecht, Utrecht, The Netherlands.
Source
Diabet Med. 2002 Mar;19(3):259
Date
Mar-2002
Language
English
Publication Type
Conference/Meeting Material
Keywords
Denmark
Diabetes mellitus
England
Humans
Netherlands
PubMed ID
11918629 View in PubMed
Less detail

Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-convergence on axonal guidance.

https://arctichealth.org/en/permalink/ahliterature260948
Source
Epilepsia. 2014 Dec;55(12):2017-27
Publication Type
Article
Date
Dec-2014
Author
Sanne S Kaalund
Morten T Venø
Mads Bak
Rikke S Møller
Henning Laursen
Flemming Madsen
Helle Broholm
Bjørn Quistorff
Peter Uldall
Niels Tommerup
Sakari Kauppinen
Anne Sabers
Kees Fluiter
Lisbeth B Møller
Anne Y Nossent
Asli Silahtaroglu
Jørgen Kjems
Eleonora Aronica
Zeynep Tümer
Source
Epilepsia. 2014 Dec;55(12):2017-27
Date
Dec-2014
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Animals
Cohort Studies
Denmark
Embryo, Mammalian
Epilepsy, Temporal Lobe - complications - metabolism - pathology
Female
Gene Expression Profiling
Gene Expression Regulation - physiology
Glutamate Plasma Membrane Transport Proteins - genetics - metabolism
Hippocampus - metabolism
Humans
Male
MicroRNAs - metabolism
Middle Aged
Nerve Tissue Proteins - metabolism
Netherlands
Pyramidal Cells - metabolism - pathology
Receptors, Metabotropic Glutamate - metabolism
Reproducibility of Results
Sclerosis - etiology - pathology
Sequence Analysis, RNA
Swine
Young Adult
Abstract
Mesial temporal lobe epilepsy (MTLE) is one of the most common types of the intractable epilepsies and is most often associated with hippocampal sclerosis (HS), which is characterized by pronounced loss of hippocampal pyramidal neurons. microRNAs (miRNAs) have been shown to be dysregulated in epilepsy and neurodegenerative diseases, and we hypothesized that miRNAs could be involved in the pathogenesis of MTLE and HS.
miRNA expression was quantified in hippocampal specimens from human patients using miRNA microarray and quantitative real-time polymerase chain reaction RT-PCR, and by RNA-seq on fetal brain specimens from domestic pigs. In situ hybridization was used to show the spatial distribution of miRNAs in the human hippocampus. The potential effect of miRNAs on targets genes was investigated using the dual luciferase reporter gene assay.
miRNA expression profiling showed that 25 miRNAs were up-regulated and 5 were down-regulated in hippocampus biopsies of MTLE/HS patients compared to controls. We showed that miR-204 and miR-218 were significantly down-regulated in MTLE and HS, and both were expressed in neurons in all subfields of normal hippocampus. Moreover, miR-204 and miR-218 showed strong changes in expression during fetal development of the hippocampus in pigs, and we identified four target genes, involved in axonal guidance and synaptic plasticity, ROBO1, GRM1, SLC1A2, and GNAI2, as bona fide targets of miR-218. GRM1 was also shown to be a direct target of miR-204.
miR-204 and miR-218 are developmentally regulated in the hippocampus and may contribute to the molecular mechanisms underlying the pathogenesis of MTLE and HS.
PubMed ID
25410734 View in PubMed
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Ablation trumps meds for atrial fibrillation treatment. Catheter ablation provides better long-term relief from atrial fibrillation than medication, but surgical ablation is best, a second study concludes.

https://arctichealth.org/en/permalink/ahliterature122994
Source
Duke Med Health News. 2012 Mar;18(3):1-2
Publication Type
Article
Date
Mar-2012

Abortion, 1973: some recent world events in relation to pregnancy termination.

https://arctichealth.org/en/permalink/ahliterature66364
Source
Trans Aust Med Congr. 1974 Jun 1;1(5):27-30
Publication Type
Article
Date
Jun-1-1974
Source
Trans Aust Med Congr. 1974 Jun 1;1(5):27-30
Date
Jun-1-1974
Language
English
Publication Type
Article
Keywords
Abortion, Induced
Americas
Developed Countries
Europe
Europe, Eastern
Family Planning Services
France
Germany, East
Germany, West
Great Britain
Italy
Netherlands
North America
Norway
Scandinavia
Sweden
United States
Abstract
This selective report notes recent events relating to pregnancy termination in the U.S., France, England, Italy, East and West Germany, Norway, Sweden, and the Netherlands. Due to the Supreme Court decision in January 1973, abortion is now legal in the U.S. Although abortions is illegal in France, an estimated 400,000-1,000,000 clandestine abortions occur each year. Although abortions are legal in Britain, the ease with which they can be obtained varies regionally. As of March 1973, contraceptives are part of Britain's National Health Service. In Italy, a bill to legalize abortion has been introduced in Parliament, though there is little likelihood of its passing. In East Germany, abortion can be granted for medical or social reasons, while in West Germany, the governmental policies are more conservative, resulting in an abundance of illegal abortions performed by physicians. There is a trend toward easier abortion laws in Norway and Sweden. Little is happening in the Netherlands as far as liberalizing the abortion laws. Rather liberal grounds for pregnancy termination exist in China (though emphasis is on contraception), India, Russia, and Eastern Europe (with the exception of Romania). Abortion is frowned upon in Africa, Latin America, and the Middle East resulting in a large number of illegal abortions. It is concluded that there is liberalized abortion in communist bloc countries, there is trend toward liberalizing abortion in a large group of western countries, and tradition and religion are responsible for conservative abortion laws in a third group of countries.
PubMed ID
12333737 View in PubMed
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Abortion in adolescence: a four-country comparison.

https://arctichealth.org/en/permalink/ahliterature63836
Source
Womens Health Issues. 2001 Mar-Apr;11(2):73-9
Publication Type
Article
Author
P. Welsh
M. McCarthy
B. Cromer
Author Affiliation
Department of Obstetrics and Gynecology, University Hospitals, Ohio State University College of Medicine and Public Health, Columbus, OH, USA.
Source
Womens Health Issues. 2001 Mar-Apr;11(2):73-9
Language
English
Publication Type
Article
Keywords
Abortion, Induced
Adolescent
Adolescent Health Services
Adult
Aged
Attitude of Health Personnel
Comparative Study
England
Female
Humans
Male
Middle Aged
Netherlands
Pregnancy
Sweden
United States
Abstract
The purpose of this study was to conduct a comparison, using qualitative analytic methodology, of perceptions concerning abortion among health care providers and administrators, along with politicians and anti-abortion activists (total n = 75) in Great Britain, Sweden, The Netherlands, and the United States. In none of these countries was there consensus about abortion prior to legalization, and, in all countries, public discussion continues to be present. In general, after legalization of abortion has no longer made it a volatile issue European countries have refocused their energy into providing family planning services, education, and more straightforward access to abortion compared with similar activities in the United States.
PubMed ID
11275509 View in PubMed
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Access Governance for Biobanks: The Case of the BioSHaRE-EU Cohorts.

https://arctichealth.org/en/permalink/ahliterature279361
Source
Biopreserv Biobank. 2016 Jun;14(3):201-6
Publication Type
Article
Date
Jun-2016
Author
Jane Kaye
Linda Briceño Moraia
Colin Mitchell
Jessica Bell
Jasper Adriaan Bovenberg
Anne-Marie Tassé
Bartha Maria Knoppers
Source
Biopreserv Biobank. 2016 Jun;14(3):201-6
Date
Jun-2016
Language
English
Publication Type
Article
Keywords
Biological Specimen Banks - legislation & jurisprudence - organization & administration
Biomedical Research - legislation & jurisprudence
Cooperative Behavior
Databases, Factual
European Union
Finland
Germany
Humans
Information Dissemination - legislation & jurisprudence
Interprofessional Relations
Netherlands
Norway
United Kingdom
Abstract
Currently, researchers have to apply separately to individual biobanks if they want to carry out studies that use samples and data from multiple biobanks. This article analyzes the access governance arrangements of the original five biobank members of the Biobank Standardisation and Harmonisation for Research Excellence in the European Union (BioSHaRE-EU) project in Finland, Germany, the Netherlands, Norway, and the United Kingdom to identify similarities and differences in policies and procedures, and consider the potential for internal policy "harmonization." Our analysis found differences in the range of researchers and organizations eligible to access biobanks; application processes; requirements for Research Ethics Committee approval; and terms of Material Transfer Agreements relating to ownership and commercialization. However, the main elements of access are the same across biobanks; access will be granted to bona fide researchers conducting research in the public interest, and all biobanks will consider the scientific merit of the proposed use and it's compatibility with the biobank's objectives. These findings suggest potential areas for harmonization across biobanks. This could be achieved through a single centralized application to a number of biobanks or a system of mutual recognition that places a presumption in favor of access to one biobank if already approved by another member of the same consortium. Biobanking and Biomolecular Resources Research Infrastructure-European Research Infrastructure Consortia (BBMRI-ERIC), a European consortium of biobanks and bioresources with its own ethical, legal, and social implications (ELSI) common service, could provide a platform by developing guidelines for harmonized internal processes.
PubMed ID
27183185 View in PubMed
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The accuracy of outcome prediction models for childhood-onset epilepsy.

https://arctichealth.org/en/permalink/ahliterature173004
Source
Epilepsia. 2005 Sep;46(9):1526-32
Publication Type
Article
Date
Sep-2005
Author
Miranda Geelhoed
Anne Olde Boerrigter
Peter Camfield
Ada T Geerts
Willem Arts
Bruce Smith
Carol Camfield
Author Affiliation
Department of Pediatric Neurology, Erasmus MC, Sophia Children's Hospital, Rotterdam, The Netherlands.
Source
Epilepsia. 2005 Sep;46(9):1526-32
Date
Sep-2005
Language
English
Publication Type
Article
Keywords
Age of Onset
Anticonvulsants - therapeutic use
Child
Child, Preschool
Cohort Studies
Electroencephalography - statistics & numerical data
Epilepsy - classification - diagnosis - drug therapy
Female
Follow-Up Studies
Humans
Intelligence Tests - statistics & numerical data
Logistic Models
Male
Models, Statistical
Netherlands
Nova Scotia
Outcome Assessment (Health Care)
Prognosis
Prospective Studies
Abstract
Two large prospective cohort studies of childhood epilepsy (Nova Scotia and the Netherlands) each developed a statistical model to predict long-term outcome. We sought to evaluate the accuracy of a prognostic model based on the two studies combined.
Analyses with classification tree models and stepwise logistic regression produced predictive models for the combined dataset and the two separate cohorts. The resulting models were then externally validated on the opposite cohort. Remission was defined as no longer receiving daily medication for any length of time at the end of follow-up.
The combined cohorts yielded 1,055 evaluable patients. At the end of follow-up (>or=5 years in >96%), 622 (59%) were in remission. By using the combined data, the classification tree model and the logistic regression model predicted the outcome correctly in approximately 70%. The classification tree model split the data on epilepsy type and age at first seizure. Predictors in the logistic regression model were: seizure number before treatment, age at first seizure, absence seizures, epilepsy types of symptomatic generalized and symptomatic partial, preexisting neurologic signs, intelligence, and the combination of febrile seizures and cryptogenic partial epilepsy. When the prediction models from each cohort were cross-validated on the opposite cohort, the outcome was predicted slightly less accurately than did the model from the combined data.
Based on currently available clinical and EEG variables, predicting the outcome of childhood epilepsy may be difficult and appears to be incorrect in about one of every three patients.
PubMed ID
16146449 View in PubMed
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[A comparative analysis of the existing standards for exposure to ultraviolet radiation].

https://arctichealth.org/en/permalink/ahliterature208776
Source
Usp Fiziol Nauk. 1997 Apr-Jun;28(2):94-106
Publication Type
Article
Author
A D Strzhizhovskii
Source
Usp Fiziol Nauk. 1997 Apr-Jun;28(2):94-106
Language
Russian
Publication Type
Article
Keywords
Animals
Dose-Response Relationship, Radiation
Humans
Maximum Allowable Concentration
Neoplasms, Radiation-Induced - etiology
Netherlands
Occupational Exposure - adverse effects - standards - statistics & numerical data
Russia
Time Factors
Ultraviolet Rays - adverse effects
United States
Abstract
Quantitative analysis of threshold limit levels of UV-irradiation in the workroom environment established in USA, Netherlands and Russia was made. Comparison of its results with modern information about effective doses and action spectra of UV-radiation biological action allowed to reveal essential differences in the approach to rate setting and in some cases presence of internal contradictions and exceeding of threshold limit levels of UV irradiation above biologically effective values. The possibility of workroom UV standards utilisation for regulation of nature UV-radiation exposures was considered.
PubMed ID
9235809 View in PubMed
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Activated dormant Cryptococcus gattii infection in a Dutch tourist who visited Vancouver Island (Canada): a molecular epidemiological approach.

https://arctichealth.org/en/permalink/ahliterature148003
Source
Med Mycol. 2010 May;48(3):528-31
Publication Type
Article
Date
May-2010
Author
Ferry Hagen
Sander van Assen
Gert Jan Luijckx
Teun Boekhout
Greetje A Kampinga
Author Affiliation
CBS-KNAW Fungal Biodiversity Centre, Yeast and Basidiomycete Research, Uppsalalaan 8, Utrecht, The Netherlands. f.hagen@cbs.knaw.nl
Source
Med Mycol. 2010 May;48(3):528-31
Date
May-2010
Language
English
Publication Type
Article
Keywords
Adult
Amplified Fragment Length Polymorphism Analysis
Canada - epidemiology
Cryptococcosis - diagnosis - epidemiology - microbiology
Cryptococcus gattii - classification - genetics - isolation & purification
DNA Fingerprinting
DNA, Fungal - genetics
Disease Outbreaks
Female
Genotype
Humans
Molecular Epidemiology
Mycological Typing Techniques
Netherlands
Travel
Abstract
An ongoing outbreak of Cryptococcus gattii-caused infections, which emerged on Vancouver Island and the Pacific Northwest, has affected more than 200 of the islands' residents, of whom eight died. While C. gattii infections are rarely described in travelers, we report a case of cryptococcosis caused by C. gattii in a patient treated with high dose corticosteroids for systemic lupus erythematosus induced autoimmune hemolytic anemia. She acquired the disease during a visit to Vancouver Island one year before the onset of the symptoms. This indicates that C. gattii may cause a dormant infection that can be activated during treatment with corticosteroids.
PubMed ID
19824880 View in PubMed
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1146 records – page 1 of 115.