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74 records – page 2 of 8.

Source
Arctic Med Res. 1995;54 Suppl 2:5-8
Publication Type
Article
Date
1995

Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women.

https://arctichealth.org/en/permalink/ahliterature98025
Source
Circ Cardiovasc Genet. 2010 Feb 1;3(1):22-30
Publication Type
Article
Date
Feb-1-2010
Author
Jari H Stengård
Greg Dyson
Ruth Frikke-Schmidt
Anne Tybjaerg-Hansen
Borge G Nordestgaard
Charles F Sing
Author Affiliation
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-5618, USA.
Source
Circ Cardiovasc Genet. 2010 Feb 1;3(1):22-30
Date
Feb-1-2010
Language
English
Geographic Location
Denmark
Publication Type
Article
Keywords
Age Factors
Aged
Algorithms
Alleles
Apolipoproteins E - genetics
Denmark
Female
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Hypertension - complications
Male
Middle Aged
Myocardial Ischemia - epidemiology - etiology - genetics
Polymorphism, Single Nucleotide
Predictive value of tests
Promoter Regions, Genetic
Risk factors
Triglycerides - blood
Abstract
OBJECTIVE: Variations in the noncoding single-nucleotide polymorphisms (SNPs) at positions 560 and 832 in the 5' promoter region of the apolipoprotein E gene define genotypes that distinguish between high and low concentrations of plasma total and high-density lipoprotein cholesterol and triglycerides. We addressed whether these genotypes improve the prediction of ischemic heart disease (IHD) in subsamples of individuals defined by traditional risk factors and the genotypes defined by the epsilon(2), epsilon(3), and epsilon(4) alleles in exon 4 of the apolipoprotein E gene. METHODS AND RESULTS: In a sample of 3686 female and 2772 male participants of the Copenhagen City Heart Study who were free of IHD events, 576 individuals (257 women, 7.0% and 319 men, 11.5%) were diagnosed as having developed IHD in 6.5 years of follow-up. Using a stepwise Patient Rule-Induction Method modeling strategy that acknowledges the complex pathobiology of IHD, we identified a subsample of 764 elderly women (> or =65 years) with hypertriglyceridemia who had a history of smoking, a history of hypertension, or a history of both in which the A(560)T(832)/A(560)T(832) and A(560)T(832)/A(560)G(832) 5' 2-SNP genotypes had a higher cumulative incidence of IHD (172/1000) compared to the incidence of 70/1000 in the total sample of women. CONCLUSIONS: Our study validates that 5' apolipoprotein E genotypes improve the prediction of IHD and documents that the improvement is greatest in a subset defined by a particular combination of traditional risk factors in Copenhagen City Heart Study female participants. We discuss the use of these genotypes in medical risk assessment of IHD in the population represented by the Copenhagen City Heart Study.
Notes
RefSource: Circ Cardiovasc Genet. 2010 Feb 1;3(1):1-2
PubMed ID
20160192 View in PubMed
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[Coronary artery disease after renal transplantation: epidemiology, risk factors, and surgical approaches to treatment].

https://arctichealth.org/en/permalink/ahliterature166298
Source
Vestn Ross Akad Med Nauk. 2006;(11):31-7
Publication Type
Article
Date
2006
Author
V I Shumakov
N A Tomilina
I G Kim
V V Chestukhin
B L Mirankov
I G Riadovoi
M G Gontuar
E N Ostroumov
A E Ermolenko
Source
Vestn Ross Akad Med Nauk. 2006;(11):31-7
Date
2006
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Child
Coronary Artery Bypass - methods
Female
Follow-Up Studies
Humans
Incidence
Kidney Transplantation - adverse effects
Male
Middle Aged
Myocardial Ischemia - epidemiology - etiology - surgery
Postoperative Complications
Risk factors
Russia - epidemiology
Survival Rate - trends
Treatment Outcome
Abstract
Coronary artery disease (CAD) is the main cause of death in renal transplant recipients. The aim of the present study was to determine the frequency and risk factors of post-transplantation CAD and its influence on the long-term results of surgery, as well as to evaluate the efficiency of myocardial revascularization in patients with severe CAD. Analysis of the observation of 479 renal recipients (332 men and 147 women) aged 38.69 +/- 11.2 was performed. The mean follow-up period was 64.56 +/- 37.44 months. Sixty-eight patients had diabetes mellitus. CAD was diagnosed in 14.8% (71 out of 479) renal recipients; in 12.7% of patients it developed de novo and was revealed 32.4 +/- 18.6 months after the surgery. Ten-year survival of renal recipients with CAD was only 39%, while in the group of non-CAD patients it was 75% (p
PubMed ID
17136851 View in PubMed
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[Coronary heart disease, its risk factors and somatic types in coal miners having chronic dust-related diseases of lungs].

https://arctichealth.org/en/permalink/ahliterature187431
Source
Med Tr Prom Ekol. 2002;(10):30-4
Publication Type
Article
Date
2002
Author
N G Stankevich
Ia A Gorbatovskii
S N Filimonov
N I Panev
M V Luk'ianova
Source
Med Tr Prom Ekol. 2002;(10):30-4
Date
2002
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Catchment Area (Health)
Chronic Disease
Coal Mining
Dust
Female
Humans
Lung Diseases - epidemiology - etiology
Male
Middle Aged
Myocardial Ischemia - epidemiology - etiology
Occupational Diseases - epidemiology
Risk factors
Russia - epidemiology
Somatoform Disorders - epidemiology
Abstract
Studies covered incidence of coronary heart disease, its risk factors and features of constitutional types among Kouzbass coal miners suffering from anthracosilicosis and chronic dust bronchitis. Findings are reliably higher incidence of coronary heart disease among coal miners having lung diseases caused by dust. Coronary heart disease among the miners with anthracosilicosis is favored by arterial hypertension, overweight and hypersthenic constitutional type, that among those with dust bronchitis is favored only by overweight.
PubMed ID
12474281 View in PubMed
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[Diabetes mellitus: its prevalence, relationship to the risk factors for IHD and prognostic importance (an epidemiological study)].

https://arctichealth.org/en/permalink/ahliterature213567
Source
Ter Arkh. 1996;68(1):15-8
Publication Type
Article
Date
1996
Author
L V Chazova
A M Kalinina
E V Markova
L I Pavlova
Source
Ter Arkh. 1996;68(1):15-8
Date
1996
Language
Russian
Publication Type
Article
Keywords
Adult
Cardiovascular Diseases - mortality
Diabetes Complications
Diabetes Mellitus - epidemiology
Female
Glucose Tolerance Test - statistics & numerical data
Humans
Male
Middle Aged
Moscow - epidemiology
Myocardial Ischemia - epidemiology - etiology
Prevalence
Prognosis
Risk factors
Urban Population - statistics & numerical data
Abstract
Sample examination of the population aged 25-64 basing on the disease history, fasting blood glucose test, glucose tolerance test, WHO criteria, diabetes mellitus was found in 6% of males and 6.9% of females. Only 2.7% of males and 3.1% of females were aware of their disease. Glucose tolerance test discovered abnormal carbohydrate tolerance in 5.6% and 13.3% of male and female examinees, respectively. Thus, a total of 12.2% of males and 20.2% of females had various disorders of carbohydrate metabolism. Diabetes mellitus patients had often hypercholesterolemia, hypertriglyceridemia, obesity, hypertension, low 10-year survival.
PubMed ID
8644021 View in PubMed
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Do general practitioner and patient agree about the risk factors for ischaemic heart disease?

https://arctichealth.org/en/permalink/ahliterature49803
Source
Scand J Prim Health Care. 2002 Mar;20(1):16-21
Publication Type
Article
Date
Mar-2002
Author
Lars Bjerrum
Lena Hamm
Birgit Toft
Anders Munck
Jakob Kragstrup
Author Affiliation
Research Unit of General Practice, University of Southern Denmark, Odense. lbjerrum@health.sdu.dk
Source
Scand J Prim Health Care. 2002 Mar;20(1):16-21
Date
Mar-2002
Language
English
Publication Type
Article
Keywords
Adult
Aged
Attitude of Health Personnel
Attitude to Health
Case-Control Studies
Communication
Cross-Sectional Studies
Denmark - epidemiology
Exercise
Female
Health Knowledge, Attitudes, Practice
Humans
Life Style
Male
Middle Aged
Myocardial Ischemia - epidemiology - etiology - psychology
Obesity - complications
Patient Education
Physician's Role
Physician-Patient Relations
Physicians, Family - psychology
Research Support, Non-U.S. Gov't
Risk assessment
Risk factors
Smoking - adverse effects
Stress, Psychological - complications
Abstract
OBJECTIVE: To analyse agreement between patients' and GPs' perceptions of risk factors and overall risk of ischaemic heart disease (IHD). DESIGN: Cross-sectional study based on paired information from patients and GPs. SETTING: Twenty-six GPs in the County of Ringkøbing, Denmark, participating in a medical audit during 3 weeks in May 1999. SUBJECTS: 252 patients with IHD and 1239 without IHD. MAIN OUTCOME MEASURES: GPs and patients were asked about specific risk factors for IHD and their perception of overall risk. Their agreement was evaluated by Kappa statistics. RESULTS: Agreement between GPs and patients varied from 70% to 97%. Disagreement was observed most often for patients with IHD and patients listed with elderly GPs ( > 50 years). Generally, patients perceived the overall risk of IHD lower than their doctors, and for most patients with a perception of low risk the GP estimated the risk as high. CONCLUSIONS: Patients and GPs have different perceptions of the risk of [HD. This may be due to different perceptions of the importance of specific risk factors and different reference frames for risk perception. GPs have an important role in communicating the meaning of risk factors and interventions should be considered to improve risk communication in general practice.
PubMed ID
12086277 View in PubMed
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The effect of age on risk factors for ischemic heart disease: the Manitoba Follow-Up Study, 1948-1993.

https://arctichealth.org/en/permalink/ahliterature204580
Source
Ann Epidemiol. 1998 Oct;8(7):415-21
Publication Type
Article
Date
Oct-1998
Author
R B Tate
J. Manfreda
T E Cuddy
Author Affiliation
Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada.
Source
Ann Epidemiol. 1998 Oct;8(7):415-21
Date
Oct-1998
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Aging
Diabetes Complications
Follow-Up Studies
Humans
Hypertension - complications
Male
Manitoba - epidemiology
Middle Aged
Myocardial Ischemia - epidemiology - etiology
Predictive value of tests
Risk
Risk factors
Smoking - adverse effects
Abstract
The purpose of this paper is to determine the age-specific relationships between risk factors at age 40 through 75 years and ischemic heart disease (IHD), and to determine the effects of aging on these relationships in a cohort of 3983 Canadian males.
The Manitoba Follow-Up Study is the prospective investigation of cardiovascular disease as it develops in a cohort of 3983 young men. Over a period of 45 years, from 1948 to 1993, 1094 study members (27%) developed clinical evidence of IHD. Blood pressure, body weight, smoking, and presence of diabetes mellitus have been recorded at regular intervals throughout the follow-up period. Using measurements from examinations every 5 years between ages 40 and 75 years, age-specific Cox proportional hazard models were fit to relate these risk factors to IHD.
The adjusted relative risk of IHD for systolic blood pressure, diastolic blood pressure and smoking were found to significantly (p 0.05). After age 65 years, these risk factors were of little value for the prediction of IHD.
The relative risk and statistical significance of blood pressure and smoking, as risk factors for IHD, decline with age.
Notes
Comment In: Ann Epidemiol. 1998 Oct;8(7):411-49738686
PubMed ID
9738687 View in PubMed
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[Effects of local vibration on development of ischemic heart disease in miners of South Kuzbas].

https://arctichealth.org/en/permalink/ahliterature187107
Source
Klin Med (Mosk). 2002;80(11):34-7
Publication Type
Article
Date
2002
Author
S N Filimonov
L A Danilevskaia
Ia A Gorbatovskii
N N Epifantseva
N G Stankevich
L V Gracheva
Source
Klin Med (Mosk). 2002;80(11):34-7
Date
2002
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Catchment Area (Health)
Humans
Male
Middle Aged
Mining
Myocardial Ischemia - epidemiology - etiology
Occupational Diseases - epidemiology - etiology
Russia - epidemiology
Vibration - adverse effects
Abstract
The incidence of ischemic heart disease (IHD) and risk factors of its genesis have been studied in 380 miners of a control group non-exposed to industrial vibration. Constitution type and a number of phenotypic signs have been determined for all examined workers with hemostatic indices defined in 60 miners before and after the performance of vibrational load test. High incidence of IHD, arterial hypertension and hyperholesterolemia have been detected in the miners working with vibration instruments and hemostatic disorders predisposing to ischemic heart disease have been revealed. In the miners of vibrodangerous occupations suffering from ischemic heart disease, hypersthenic constitution type determined by Rees-Eysenc index less than 92.2 and the height below 170 cm was found to occur more frequently.
PubMed ID
12516338 View in PubMed
Less detail

[Epidemiological risk assessment of pathology development in occupational exposure to radiofrequency electromagnetic fields].

https://arctichealth.org/en/permalink/ahliterature182530
Source
Radiats Biol Radioecol. 2003 Sep-Oct;43(5):559-64
Publication Type
Article
Author
G I Tikhonova
Author Affiliation
Research Institute of Occupational Health, Moscow, 105275 Russia. Tichon_I@mail.ru
Source
Radiats Biol Radioecol. 2003 Sep-Oct;43(5):559-64
Language
Russian
Publication Type
Article
Keywords
Adult
Aerospace Medicine
Age Factors
Cardiovascular Diseases - epidemiology - etiology
Cross-Sectional Studies
Electromagnetic fields - adverse effects
Health status
Humans
Hypertension - epidemiology - etiology
Male
Middle Aged
Myocardial Infarction - epidemiology - etiology
Myocardial Ischemia - epidemiology - etiology
Occupational Diseases - epidemiology - etiology
Prevalence
Radar
Risk assessment
Russia - epidemiology
Sex Factors
Stress, Psychological - complications - epidemiology - etiology
Abstract
A cross-sectional study of working conditions and health of the personnel of the civil aircraft radar-tracking system has been conducted based on periodical health examinations. The personnel was divided into three occupational groups. Group I was exposed to EMF EHF, group II--to EMF HF and UHF and group III was not exposed to EMF (reference group). The groups didn't differ in any occupational and non-occupational parameters. Health status of 250 workers was examined. High prevalence rate of cardiovascular diseases (ICD-X I00-I99) was found in the exposed groups. Odds ratio (OR) was 3.78 (95% CI 1.96-7.27) in group I and 2.13 (95% CI 1.13-4.03) in group II. High prevalence rate of cardiovascular diseases is explained by arterial hypertension (ICD-X I10-I15) (OR = 1.96 95% CI 1.04-3.70 in group I and OR = 1.80 95% CI 0.93-3.50 in group II) and ischemic heart disease (ICD-X I20-I25) (OR = 7.9 95% CI 3.48-18.06 in group I; OR = 3.0 95% CI 1.23-7.33--in group II). In the exposed groups cardiovascular diseases were developed in young age. OR was 7.04 (95% CI 1.64-30.19) in group I and 4.33 (95% CI 0.96-19.65) in group II in 30-39 age sub groups. Myocardium infarction was found in 2 out of 16 persons of this age in the group exposed to EMF.
PubMed ID
14658291 View in PubMed
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Factors predictive of ischemic heart disease mortality in foundry workers exposed to carbon monoxide.

https://arctichealth.org/en/permalink/ahliterature196947
Source
Am J Epidemiol. 2000 Oct 1;152(7):628-32
Publication Type
Article
Date
Oct-1-2000
Author
R S Koskela
P. Mutanen
J A Sorsa
M. Klockars
Author Affiliation
Finnish Institute of Occupational Health, Helsinki. riitta-sisko.koskela@occuphealth.fi
Source
Am J Epidemiol. 2000 Oct 1;152(7):628-32
Date
Oct-1-2000
Language
English
Publication Type
Article
Keywords
Air Pollutants, Occupational - analysis
Blood pressure
Carbon Monoxide - adverse effects - analysis
Confounding Factors (Epidemiology)
Electrocardiography
Finland - epidemiology
Follow-Up Studies
Humans
Hypertension - complications
Male
Metallurgy
Myocardial Ischemia - epidemiology - etiology - mortality
Occupational Exposure - adverse effects - standards
Proportional Hazards Models
Questionnaires
Registries
Smoking - adverse effects
Abstract
The potential predictors of ischemic heart disease mortality were studied for 931 male foundry workers in Finland who participated in a health examination in 1973. These workers were followed up to 1993 through registers and by using a questionnaire. In 1973, the systolic and diastolic blood pressures of workers exposed to carbon monoxide (CO) were slightly higher than those of unexposed workers. The prevalence of angina pectoris showed a clear dose-response relation to CO exposure. Electrocardiogram (ECG) findings indicating past myocardial infarction or suggesting coronary artery disease as a function of smoking and/or CO exposure were not evident. In the 1987 follow-up, the rate ratio for ischemic heart disease mortality was estimated as 4.4 for CO-exposed smokers compared with unexposed nonsmokers. Ischemic heart disease mortality in 1973-1993 was analyzed by using the Cox proportional hazards model. The statistically significant predictors were age, pathologic ECG findings in 1973, regular CO exposure, and abundant alcohol drinking. Of the ECG findings, changes in Q or QS and ST-J or ST waves and in ventricular extrasystoles were statistically significant. The risk of mortality from ischemic heart disease was increased by working in iron foundries, by hypertension, and by smoking.
PubMed ID
11032157 View in PubMed
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74 records – page 2 of 8.