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625 records – page 1 of 63.

3-D modeling substantiates perfluorinated theory.

https://arctichealth.org/en/permalink/ahliterature82705
Source
Environ Sci Technol. 2006 Feb 1;40(3):632-3
Publication Type
Article
Date
Feb-1-2006
Author
Renner Rebecca
Source
Environ Sci Technol. 2006 Feb 1;40(3):632-3
Date
Feb-1-2006
Language
English
Publication Type
Article
Keywords
Air Movements
Alcohols
Arctic Regions
Environmental Pollutants - analysis
Fluorocarbons - analysis - chemistry
Industry
Manufactured Materials
Models, Theoretical
Octanoic Acids - analysis - chemistry
Notes
Comment On: Environ Sci Technol. 2006 Feb 1;40(3):924-3016509338
PubMed ID
16509290 View in PubMed
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5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin.

https://arctichealth.org/en/permalink/ahliterature15223
Source
J Allergy Clin Immunol. 2003 Oct;112(4):768-74
Publication Type
Article
Date
Oct-2003
Author
Shigeo Muro
Qutayba Hamid
Ronald Olivenstein
Rame Taha
Joshua Rokach
William S Powell
Author Affiliation
Department of Medicine, McGill University, Montreal, Quebec, Canada.
Source
J Allergy Clin Immunol. 2003 Oct;112(4):768-74
Date
Oct-2003
Language
English
Publication Type
Article
Keywords
Arachidonic Acids - pharmacology
Asthma - physiopathology
Case-Control Studies
Cell Movement - drug effects
Chemotactic Factors - pharmacology
Granulocytes - drug effects - pathology
Humans
Macrophages - pathology
Mast Cells - pathology
Neutrophils - pathology
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Skin - pathology
Time Factors
Abstract
BACKGROUND: 5-Oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) is an arachidonic acid metabolite with potent in vitro chemoattractant effects on eosinophils and neutrophils. It has also been shown to induce pulmonary eosinophilia in Brown Norway rats, but it is not known whether it is active in human beings in vivo. OBJECTIVE: To determine whether 5-oxo-ETE can induce cellular infiltration in patients with atopic asthma and nonatopic control subjects after intradermal administration. METHODS: 5-Oxo-ETE was administered intradermally to 11 patients with atopic asthma and 10 nonatopic control subjects. Skin biopsy specimens were taken 6 or 24 hours later and examined by immunocytochemistry for cells expressing specific markers for eosinophils (major basic protein), neutrophils (elastase), macrophages (CD68), lymphocytes (CD3), and mast cells (tryptase). RESULTS: 5-Oxo-ETE (1.5 and 5 microg) elicited the infiltration of both eosinophils and neutrophils into the skin in both control and atopic asthmatic subjects. Increased numbers of eosinophils were observed at 6 and 24 hours after injection, whereas significantly elevated neutrophil numbers were present only after 24 hours. Eosinophils were >3 times higher in patients with atopic asthma compared with control subjects after injection of the highest dose of 5-oxo-ETE. Macrophage numbers were also elevated, but only at the highest dose of 5-oxo-ETE. No effects were observed on the numbers of either lymphocytes or mast cells. CONCLUSIONS: 5-Oxo-ETE elicits the infiltration of eosinophils and neutrophils into the skin of human beings in vivo after intradermal administration. Asthmatic subjects are more responsive to this substance than nonallergic control subjects. These results suggest that 5-oxo-ETE may be an important mediator of inflammation.
PubMed ID
14564360 View in PubMed
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A 10-week strength training program: effect on the motor performance of an unimpaired upper extremity.

https://arctichealth.org/en/permalink/ahliterature50029
Source
Arch Phys Med Rehabil. 1998 Aug;79(8):925-30
Publication Type
Article
Date
Aug-1998
Author
K J Kauranen
P T Siira
H V Vanharanta
Author Affiliation
Department of Physical Medicine and Rehabilitation, Oulu University Central Hospital, Finland.
Source
Arch Phys Med Rehabil. 1998 Aug;79(8):925-30
Date
Aug-1998
Language
English
Publication Type
Article
Keywords
Adult
Arm - physiology
Electromyography
Exercise Therapy - methods
Female
Hand Strength - physiology
Humans
Middle Aged
Motor Skills - physiology
Movement - physiology
Weight Lifting
Abstract
OBJECTIVE: Muscle strength training is one of the most common therapy methods in physical therapy programs, and the usual goal of this treatment is to improve muscle strength. Little attention has been paid, however, to the effects of strength training on the other components of motor performance. This study examined the effects of a 10-week strength training program on the motor performance of the hand, including reaction time, speed of movement, tapping speed, and coordination in normal healthy volunteers. DESIGN: Before-after trial. SUBJECTS AND SETTING: Sixteen healthy women volunteers aged 25 to 45 years participated. INTERVENTION: Subjects accomplished a 10-week muscle strength training program of the upper extremities. MAIN OUTCOME MEASURES: Reaction time, speed of movement, tapping speed, and coordination were measured three times on consecutive days, and muscle strength and electromyographic values of the right upper extremity were recorded once before the training period. After the training period, the same measurements were made as before the training. RESULTS: The 10-week strength training decreased choice reaction time by 6% (p
PubMed ID
9710164 View in PubMed
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A 10-year follow-up review of patients who underwent Leksell's posteroventral pallidotomy for Parkinson disease.

https://arctichealth.org/en/permalink/ahliterature71973
Source
J Neurosurg. 2001 Apr;94(4):552-8
Publication Type
Article
Date
Apr-2001
Author
M I Hariz
A T Bergenheim
Author Affiliation
Department of Neurosurgery, University Hospital of Northern Sweden, Umeå. marwan.hariz@neuro.umu.se
Source
J Neurosurg. 2001 Apr;94(4):552-8
Date
Apr-2001
Language
English
Publication Type
Article
Keywords
Adult
Aged
Antiparkinson Agents - therapeutic use
Cognition
Dopamine Agents - therapeutic use
Dopamine Agonists - therapeutic use
Female
Follow-Up Studies
Globus Pallidus - surgery
Humans
Levodopa - therapeutic use
Male
Middle Aged
Movement
Parkinson Disease - drug therapy - physiopathology - psychology - surgery
Recurrence
Abstract
OBJECT: The clinical condition of patients with Parkinson disease (PD) who had undergone posteroventral pallidotomy (PVP) between 1985 and 1990 was evaluated at a mean of 10 years postsurgery. These patients were part of a larger series described in the first paper on Leksell's PVP that was published in 1992. METHODS: Thirteen consecutive patients who had undergone pallidotomy at the University Hospital of Northern Sweden were tracked. Hospital and clinic records that had been updated regularly by the patients' various neurologists, geriatricians, and other clinicians were reviewed. Emphasis was placed on assessing the evolution of PD symptoms after surgery, and changes in the general health and social condition of the patients. The mean follow-up duration was 10.5 years (range 3-13.5 years). Five patients underwent a total of seven subsequent surgeries for their PD, 4 months to 11 years after the initial pallidotomy. The mean Hoehn and Yahr stage was 3 at the first surgery and 3.7 at the last follow-up review (p
PubMed ID
11302652 View in PubMed
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17-year follow-up of symptoms and signs in the knee joint in rheumatoid arthritis.

https://arctichealth.org/en/permalink/ahliterature14565
Source
Scand J Rheumatol. 1988;17(5):325-31
Publication Type
Article
Date
1988
Author
J. Isacson
E. Allander
L A Broström
Author Affiliation
Department of Orthopedic Surgery, Karolinska Hospital, Stockholm, Sweden.
Source
Scand J Rheumatol. 1988;17(5):325-31
Date
1988
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Arthritis, Rheumatoid - physiopathology - radiography - surgery
Female
Forecasting
Humans
Knee Joint - physiopathology - radiography - surgery
Locomotion
Male
Middle Aged
Movement
Research Support, Non-U.S. Gov't
Rheumatoid Factor - analysis
Abstract
A population survey was carried out in Stockholm, Sweden, in 1967. In a sample of 15,268 individuals, 239 were found to have rheumatoid arthritis according to the New York diagnostic criteria. In 1983, i.e. 17 years later, 109 of the 127 individuals still living were reexamined. Among these, 79 complained of knee symptoms and 30 stated that the knee was the joint that presented the greatest hindrance to walking. Fifty-nine found difficulty in walking up or down stairs and 47 had to use a walking aid. These shortcomings were more often noted in the knees that had been swollen, or painful, 17 years previously. In addition, at follow-up, narrowing of the articular space was observed in the knees that were swollen and painful. Valgus deformity was associated with swelling, while varus deformity also involved, apart from the swelling, pain and restricted motility. In all, 108 operations were performed on 48 of the 109 subjects who were re-examined; 12 of these were knee operations.
PubMed ID
3212404 View in PubMed
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30 years of data reveal dramatic increase in abundance of brown trout following the removal of a small hydrodam.

https://arctichealth.org/en/permalink/ahliterature292608
Source
J Environ Manage. 2017 Dec 15; 204(Pt 1):467-471
Publication Type
Journal Article
Date
Dec-15-2017
Author
Kim Birnie-Gauvin
Martin H Larsen
Jan Nielsen
Kim Aarestrup
Author Affiliation
DTU Aqua, Section for Freshwater Fisheries and Ecology, Vejlsøvej 39, 8600 Silkeborg, Denmark. Electronic address: kbir@aqua.dtu.dk.
Source
J Environ Manage. 2017 Dec 15; 204(Pt 1):467-471
Date
Dec-15-2017
Language
English
Publication Type
Journal Article
Keywords
Animals
Conservation of Natural Resources - methods
Denmark
Ecosystem
Rivers
Trout
Water Movements
Abstract
Humans and freshwater ecosystems have a long history of cohabitation. Today, nearly all major rivers of the world have an in-stream structure which changes water flow, substrate composition, vegetation, and fish assemblage composition. The realization of these effects and their subsequent impacts on population sustainability and conservation has led to a collective effort aimed to find ways to mitigate these impacts. Barrier removal has recently received greater interest as a potential solution to restore river connectivity, and reestablish high quality habitats, suitable for feeding, refuge and spawning of fish. In the present study, we present thirty years of data from electrofishing surveys obtained at two sites, both prior to and following the removal of a small-scale hydropower dam in Central Jutland, Denmark. We demonstrate that the dam removal has led to a dramatic increase in trout density, especially in young of the year. Surprisingly, we found that this increase was not just upstream of the barrier, where the ponded zone previously was, but also downstream of the barrier, despite little changes in habitat in that area. These findings suggest that barrier removal may be the soundest conservation option to reinstate fish population productivity.
PubMed ID
28923580 View in PubMed
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Abnormal maturation of the retinal vasculature in type XVIII collagen/endostatin deficient mice and changes in retinal glial cells due to lack of collagen types XV and XVIII.

https://arctichealth.org/en/permalink/ahliterature50565
Source
FASEB J. 2005 Sep;19(11):1564-6
Publication Type
Article
Date
Sep-2005
Author
Merja Hurskainen
Lauri Eklund
Pasi O Hägg
Marcus Fruttiger
Raija Sormunen
Mika Ilves
Taina Pihlajaniemi
Author Affiliation
Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.
Source
FASEB J. 2005 Sep;19(11):1564-6
Date
Sep-2005
Language
English
Publication Type
Article
Keywords
Animals
Astrocytes - physiology
Cell Movement
Collagen - physiology
Collagen Type XVIII - deficiency - physiology
Endostatins - physiology
Mice
Mice, Inbred C57BL
Neovascularization, Physiologic
Neuroglia - physiology
Oxygen - pharmacology
Platelet-Derived Growth Factor - genetics
RNA, Messenger - analysis
Research Support, Non-U.S. Gov't
Retina - pathology
Retinal Vessels - physiology
Vascular Endothelial Growth Factor A - genetics
Vitreous Body - blood supply
Abstract
Type XVIII collagen is important in the early phase of retinal vascular development and for the regression of the primary vasculature in the vitreous body after birth. We show here that the retina in Col18a1-/- mice becomes densely vascularized by anomalous anastomoses from the persistent hyaloid vasculature by day 10 after birth. In situ hybridizations revealed normal VEGF mRNA expression, but the phenotype of collagen XVIII deficient mice closely resembled that of mice expressing VEGF120 and VEGF188 isoforms only, suggesting that type XVIII collagen may be involved in VEGF function. Type XVIII collagen was found to be indispensable for angiogenesis in the eye, as also oxygen-induced neovascularization was less intense than normal in the Col18a1-/- mice. We observed a marked increase in the amount of retinal astrocytes in the Col18a1-/- mice. Whereas the retinal vessels of wild-type mice are covered by astrocytes and the regressing, thin hyaloid vessels are devoid of astrocytes, the retinal vessels in the Col18a1-/- mice were similarly covered by astrocytes but not the persistent hyaloid vessels in the vitreous body. Interestingly, double null mice lacking type XVIII collagen and its homologue type XV collagen had the persistent hyaloid vessels covered by astrocytes, including the parts located in the vitreous body. We thus hypothesize that type XV collagen is a regulator of glial cell recruitment around vessels and that type XVIII collagen regulates their proliferation.
PubMed ID
15976268 View in PubMed
Less detail

Acceleration and sprint profiles of a professional elite football team in match play.

https://arctichealth.org/en/permalink/ahliterature267270
Source
Eur J Sport Sci. 2015;15(2):101-10
Publication Type
Article
Date
2015
Author
Jørgen Ingebrigtsen
Terje Dalen
Geir Håvard Hjelde
Barry Drust
Ulrik Wisløff
Source
Eur J Sport Sci. 2015;15(2):101-10
Date
2015
Language
English
Publication Type
Article
Keywords
Acceleration
Athletic Performance
Football
Humans
Movement
Norway
Physical Exertion
Running
Soccer
Walking
Abstract
The aim of this study was to characterise the acceleration and sprint profiles of elite football match play in one Norwegian elite football team (Rosenborg FC). Fifteen professional players in five playing positions took part in the study (n = 101 observations). Player movement was recorded during every domestic home game of one full season (n = 15) by an automatic tracking system based on microwave technology. Each player performed 91 ± 21 accelerations per match, with a lower number in the second compared with the first half (47 ± 12 vs. 44 ± 12). Players in lateral positions accelerated more often compared to players in central positions (98.3 ± 20.5 vs. 85.3 ± 19.5, p
PubMed ID
25005777 View in PubMed
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Acceptability and concurrent validity of measures to predict older driver involvement in motor vehicle crashes: an Emergency Department pilot case-control study.

https://arctichealth.org/en/permalink/ahliterature161383
Source
Accid Anal Prev. 2007 Sep;39(5):1056-63
Publication Type
Article
Date
Sep-2007
Author
Frank J Molnar
Shawn C Marshall
Malcolm Man-Son-Hing
Keith G Wilson
Anna M Byszewski
Ian Stiell
Author Affiliation
CanDRIVE(1): a Canadian Institutes of Health Research (CIHR) Institute of Aging funded New Emerging Team, Elisabeth-Bruyère Research Institute, 43 Bruyère Street, Ottawa, ON, Canada K1N 5C8. fmolnar@ottawahospital.on.ca
Source
Accid Anal Prev. 2007 Sep;39(5):1056-63
Date
Sep-2007
Language
English
Publication Type
Article
Keywords
Accidents, Traffic - prevention & control - statistics & numerical data
Aged
Automobile Driver Examination - statistics & numerical data
Case-Control Studies
Chronic Disease - epidemiology
Dementia - diagnosis - epidemiology
Disability Evaluation
Female
Head Movements
Humans
Male
Mass Screening - statistics & numerical data
Mental Status Schedule - statistics & numerical data
Motor Skills
Neuropsychological Tests - statistics & numerical data
Ontario
Pilot Projects
Psychomotor Performance
Questionnaires
Reaction Time
Risk
Visual Fields
Wounds and injuries - epidemiology - prevention & control
Abstract
Older drivers have one of the highest motor vehicle crash (MVC) rates per kilometer driven, largely due to the functional effects of the accumulation, and progression of age-associated medical conditions that eventually impact on fitness-to-drive. Consequently, physicians in many jurisdictions are legally mandated to report to licensing authorities patients who are judged to be medically at risk for MVCs. Unfortunately, physicians lack evidence-based tools to assess the fitness-to-drive of their older patients. This paper reports on a pilot study that examines the acceptability and association with MVC of components of a comprehensive clinical assessment battery.
To evaluate the acceptability to participants of components of a comprehensive assessment battery, and to explore potential predictors of MVC that can be employed in front-line clinical settings.
Case-control study of 10 older drivers presenting to a tertiary care hospital emergency department after involvement in an MVC and 20 age-matched controls.
The measures tested were generally found to be acceptable to participants. Positive associations (p
PubMed ID
17854579 View in PubMed
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Accumulated state of the Yukon River watershed: part I critical review of literature.

https://arctichealth.org/en/permalink/ahliterature121234
Source
Integr Environ Assess Manag. 2013 Jul;9(3):426-38
Publication Type
Article
Date
Jul-2013
Author
Monique G Dubé
Breda Muldoon
Julie Wilson
Karonhiakta'tie Bryan Maracle
Author Affiliation
Canadian Rivers Institute, University of New Brunswick, Alberta, Canada. Dub.mon@hotmail.com
Source
Integr Environ Assess Manag. 2013 Jul;9(3):426-38
Date
Jul-2013
Language
English
Publication Type
Article
Keywords
Alaska - epidemiology
Animal Migration
Animals
British Columbia - epidemiology
Climate change
Environment
Environmental Monitoring - methods
Fish Diseases - epidemiology - microbiology - parasitology
Fishes - physiology
Fresh Water - analysis - microbiology - parasitology
Humans
Neoplasms - chemically induced - epidemiology
Seasons
Water Movements
Water Pollutants, Chemical - analysis - metabolism - toxicity
Water Quality
Yukon Territory - epidemiology
Abstract
A consistent methodology for assessing the accumulating effects of natural and manmade change on riverine systems has not been developed for a whole host of reasons including a lack of data, disagreement over core elements to consider, and complexity. Accumulated state assessments of aquatic systems is an integral component of watershed cumulative effects assessment. The Yukon River is the largest free flowing river in the world and is the fourth largest drainage basin in North America, draining 855,000 km(2) in Canada and the United States. Because of its remote location, it is considered pristine but little is known about its cumulative state. This review identified 7 "hot spot" areas in the Yukon River Basin including Lake Laberge, Yukon River at Dawson City, the Charley and Yukon River confluence, Porcupine and Yukon River confluence, Yukon River at the Dalton Highway Bridge, Tolovana River near Tolovana, and Tanana River at Fairbanks. Climate change, natural stressors, and anthropogenic stresses have resulted in accumulating changes including measurable levels of contaminants in surface waters and fish tissues, fish and human disease, changes in surface hydrology, as well as shifts in biogeochemical loads. This article is the first integrated accumulated state assessment for the Yukon River basin based on a literature review. It is the first part of a 2-part series. The second article (Dubé et al. 2013a, this issue) is a quantitative accumulated state assessment of the Yukon River Basin where hot spots and hot moments are assessed outside of a "normal" range of variability.
PubMed ID
22927161 View in PubMed
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625 records – page 1 of 63.