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The 1891-1920 birth cohort of Quebec chrysotile miners and millers: mortality 1976-88.

https://arctichealth.org/en/permalink/ahliterature219707
Source
Br J Ind Med. 1993 Dec;50(12):1073-81
Publication Type
Article
Date
Dec-1993
Author
J C McDonald
F D Liddell
A. Dufresne
A D McDonald
Author Affiliation
School of Occupational Health, McGill University, Montreal, Canada.
Source
Br J Ind Med. 1993 Dec;50(12):1073-81
Date
Dec-1993
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Asbestos, Serpentine
Asbestosis - mortality
Cause of Death
Cohort Studies
Humans
Lung Neoplasms - mortality
Male
Mesothelioma - mortality
Middle Aged
Mining
Occupational Exposure
Quebec - epidemiology
Smoking - mortality
Time Factors
Abstract
A cohort of some 11,000 men born 1891-1920 and employed for at least one month in the chrysotile mines and mills of Quebec, was established in 1966 and has been followed ever since. Of the 5351 men surviving into 1976, only 16 could not be traced; 2508 were still alive in 1989, and 2827 had died; by the end of 1992 a further 698 were known to have died, giving an overall mortality of almost 80%. This paper presents the results of analysis of mortality for the period 1976 to 1988 inclusive, obtained by the subject-years method, with Quebec mortality for reference. In many respects the standardised mortality ratios (SMRs) 20 years or more after first employment were similar to those for the period 1951-75--namely, all causes 1.07 (1951-75, 1.09); heart disease 1.02 (1.04); cerebrovascular disease 1.06 (1.07); external causes 1.17 (1.17). The SMR for lung cancer, however, rose from 1.25 to 1.39 and deaths from mesothelioma increased from eight (10 before review) to 25; deaths from respiratory tuberculosis fell from 57 to five. Among men whose exposure by age 55 was at least 300 million particles per cubic foot x years (mpcf.y), the SMR (all causes) was elevated in the two main mining regions, Asbestos and Thetford Mines, and for the small factory in Asbestos; so were the SMRs for lung cancer, ischaemic heart disease, cerebrovascular disease, and respiratory disease other than pneumoconiosis. Except for lung cancer, however, there was little convincing evidence of gradients over four classes of exposure, divided at 30, 100, and 300 mpcf.y. Over seven narrower categories of exposure up to 300 mpcf.y the SMR for lung cancer fluctuated around 1.27 with no indication of trend, but increased steeply above that level. Mortality form pneumoconiosis was strongly related to exposure, and the trend for mesothelioma was not dissimilar. Mortality generally was related systematically to cigarette smoking habit, recorded in life from 99% of survivors into 1976; smokers of 20 or more cigarettes a day had the highest SMRs not only for lung cancer but also for all causes, cancer of the stomach, pancreas, and larynx, and ischaemic heart disease. For lung cancer SMRs increased fivefold with smoking, but the increase with dust exposure was comparatively slight for non-smokers, lower again for ex-smokers, and negligible for smokers of at least 20 cigarettes a day; thus the asbestos-smoking interaction was less than multiplicative. Of the 33 deaths from mesothelioma in the cohort to date, 28 were in miners and millers and five were in employees of a small asbestos products factory where commercial amphiboles had also been used. Preliminary analysis also suggest that the risk of mesothelioma was higher in the mines and mills at Thetford Mines than in those at Asbestos. More detailed studies of these differences and of exposure-response relations for lung cancer are under way.
Notes
Cites: Br J Ind Med. 1980 Feb;37(1):11-247370189
Cites: Br J Cancer. 1982 Jan;45(1):124-357059455
Cites: Biometrics. 1983 Mar;39(1):173-846871346
Cites: Br J Ind Med. 1987 Jun;44(6):396-4013606968
Cites: Ann N Y Acad Sci. 1979;330:91-116294225
Cites: Br J Ind Med. 1992 Aug;49(8):566-751325180
Cites: Arch Environ Health. 1971 Jun;22(6):677-865574010
Cites: Arch Environ Health. 1972 Mar;24(3):189-975059627
Cites: Br J Ind Med. 1991 Aug;48(8):543-71878311
PubMed ID
8280638 View in PubMed
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[Accumulation of heavy metals in biologic materials of mining workers and of nearby population].

https://arctichealth.org/en/permalink/ahliterature176713
Source
Med Tr Prom Ekol. 2004;(11):38-40
Publication Type
Article
Date
2004
Author
M A Mukasheva
Source
Med Tr Prom Ekol. 2004;(11):38-40
Date
2004
Language
Russian
Publication Type
Article
Keywords
Adult
Catchment Area (Health)
Environmental monitoring
Epidemiological Monitoring
Hair - chemistry
Humans
Metals, Heavy - analysis
Middle Aged
Mining
Occupational Diseases - epidemiology - metabolism
Russia - epidemiology
Abstract
The article contains results concerning spectral analysis of biologic materials (blood and hair) for heavy metals content. These results helped to reveal health risk factors for workers engaged into chromium ores extraction and for nearby residents.
PubMed ID
15636126 View in PubMed
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[Accumulation of radionuclides in food chains of the Yenisei River after the nuclear power plant shutdown at the mining-and-chemical enterprise].

https://arctichealth.org/en/permalink/ahliterature261756
Source
Radiats Biol Radioecol. 2014 Jul-Aug;54(4):405-14
Publication Type
Article
Author
T A Zotina
E A Trofimova
A D Karpov
A Ia Bolsunovskii
Source
Radiats Biol Radioecol. 2014 Jul-Aug;54(4):405-14
Language
Russian
Publication Type
Article
Keywords
Animals
Biota
Chemical Industry
Fishes - metabolism
Food chain
Industrial Waste - analysis
Mining
Muscle, Skeletal - radionuclide imaging
Nuclear Power Plants
Radiation Monitoring - methods
Radioisotopes - analysis - pharmacokinetics
Rivers - chemistry
Seasons
Siberia
Water Pollutants, Radioactive - analysis - pharmacokinetics
Abstract
Accumulation of artificial and natural radionuclides in the chains of food webs leading to non-predatory and piscivorous fish of the Yenisei River was investigated during one year before and three years after the shutdown of a nuclear power plant at the Mining-and-Chemical Combine (2009-2012). The activity of artificial radionuclides in the samples of biota ofthe Yenisei River (aquatic moss, gammarids, dace, grayling, pike) was estimated. The concentration of radionuclides with induced activity (51Cr, 54Mn, 58Co, 60Co, 65Zn, 141, 144Ce, 152, 154Eu, 239Np) decreased in the biomass of biota after the shutdown of the nuclear power plant; the concentration of 137Cs did not. Analysis of the accumulation factors (C(F)) allows us to expect the effective accumulation of 137Cs in the terminal level of the food web of the Yenisei River--pike (C(F) = 2.0-9.4), i.e. biomagnifications of radiocesium. Accumulation of artificial, radionuclides in non-predatory fish from gammarids was not effective (C(F)
PubMed ID
25775829 View in PubMed
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Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: a validation study using the medical records of rheumatologists.

https://arctichealth.org/en/permalink/ahliterature114676
Source
Arthritis Care Res (Hoboken). 2013 Oct;65(10):1582-91
Publication Type
Article
Date
Oct-2013
Author
Jessica Widdifield
Sasha Bernatsky
J Michael Paterson
Karen Tu
Ryan Ng
J Carter Thorne
Janet E Pope
Claire Bombardier
Author Affiliation
University of Toronto, Toronto, Ontario, Canada.
Source
Arthritis Care Res (Hoboken). 2013 Oct;65(10):1582-91
Date
Oct-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Algorithms
Arthritis, Rheumatoid - diagnosis - epidemiology
Data Mining - statistics & numerical data
Databases, Factual - statistics & numerical data
Drug Prescriptions - statistics & numerical data
Fees and Charges - statistics & numerical data
Female
Hospitalization - statistics & numerical data
Humans
Male
Medical Records Systems, Computerized - statistics & numerical data
Middle Aged
Ontario - epidemiology
Reproducibility of Results
Retrospective Studies
Rheumatology - statistics & numerical data
Single-Payer System - statistics & numerical data
Abstract
Health administrative data can be a valuable tool for disease surveillance and research. Few studies have rigorously evaluated the accuracy of administrative databases for identifying rheumatoid arthritis (RA) patients. Our aim was to validate administrative data algorithms to identify RA patients in Ontario, Canada.
We performed a retrospective review of a random sample of 450 patients from 18 rheumatology clinics. Using rheumatologist-reported diagnosis as the reference standard, we tested and validated different combinations of physician billing, hospitalization, and pharmacy data.
One hundred forty-nine rheumatology patients were classified as having RA and 301 were classified as not having RA based on our reference standard definition (study RA prevalence 33%). Overall, algorithms that included physician billings had excellent sensitivity (range 94-100%). Specificity and positive predictive value (PPV) were modest to excellent and increased when algorithms included multiple physician claims or specialist claims. The addition of RA medications did not significantly improve algorithm performance. The algorithm of "(1 hospitalization RA code ever) OR (3 physician RA diagnosis codes [claims] with =1 by a specialist in a 2-year period)" had a sensitivity of 97%, specificity of 85%, PPV of 76%, and negative predictive value of 98%. Most RA patients (84%) had an RA diagnosis code present in the administrative data within ±1 year of a rheumatologist's documented diagnosis date.
We demonstrated that administrative data can be used to identify RA patients with a high degree of accuracy. RA diagnosis date and disease duration are fairly well estimated from administrative data in jurisdictions of universal health care insurance.
PubMed ID
23592598 View in PubMed
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[A comparative analysis of different approaches to identifying cardiovascular diseases in coal miners during medical selection]

https://arctichealth.org/en/permalink/ahliterature49975
Source
Lik Sprava. 1999 Mar;(2):130-5
Publication Type
Article
Date
Mar-1999
Author
L N Sizonenko
V V Cherkesov
Source
Lik Sprava. 1999 Mar;(2):130-5
Date
Mar-1999
Language
Russian
Publication Type
Article
Keywords
Adult
Cardiovascular Diseases - diagnosis
Coal Mining
Comparative Study
Echocardiography
Electrocardiography
English Abstract
Exercise Test
Humans
Male
Middle Aged
Occupational Diseases - diagnosis
Personnel Selection - methods
Risk factors
Ukraine
Work Capacity Evaluation
Abstract
An expert evaluation of identifiability of cardiovascular diseases was carried out together with a clinical and functional examination of certain groups of miners of basic underground occupations at different ages and lengths of service, that showed a high incidence of cardiovascular diseases along with a low informative value of methodical approaches, indices and criteria used for their diagnosis in conducting preliminary and periodic health check-ups. To improve the quality of diagnosis of diseases of the circulatory system it is necessary that standardized methods of investigation should be employed together with consistent indices of high informative value as well as a purposive training of physicians.
PubMed ID
10424067 View in PubMed
Less detail

[Aerogenic risk factors and diagnosis of bauxite pneumoconiosis].

https://arctichealth.org/en/permalink/ahliterature112905
Source
Med Tr Prom Ekol. 2013;(1):15-8
Publication Type
Article
Date
2013
Author
A O Peshkova
N A Roslaia
O F Roslyi
E I Likhacheva
A A Fedoruk
T V Slyshkina
E R Vagina
Source
Med Tr Prom Ekol. 2013;(1):15-8
Date
2013
Language
Russian
Publication Type
Article
Keywords
Air Pollutants, Occupational - adverse effects
Aluminum Oxide - adverse effects
Humans
Male
Middle Aged
Mining - manpower - standards
Occupational Exposure - adverse effects
Pneumoconiosis - diagnosis - epidemiology
Risk factors
Russia - epidemiology
Abstract
The research purpose is an estimation of influence of the bauxite dust on the state of the bronchopulmonary system of workers. It has been indicated that exposure of the poor fibrogenic dust while the process of the bauxite ore extraction, results in development of pnevmokoniosis characterized by substantial ventilatory and haemodynamic disorders limiting the workability of patients.
PubMed ID
23785803 View in PubMed
Less detail

[Age features of epidemiology of arterial hypertension in workers of the coal-mining enterprises].

https://arctichealth.org/en/permalink/ahliterature138281
Source
Adv Gerontol. 2011;24(4):697-700
Publication Type
Article
Date
2011
Author
S A Maksimov
A E Scripchenko
E V Indukaeva
É B Shapovalova
M Iu Iankin
T A Mulerova
N N Kozyreva
V A Semenikhin
M Iu Ogarkov
G V Artamonova
Source
Adv Gerontol. 2011;24(4):697-700
Date
2011
Language
Russian
Publication Type
Article
Keywords
Adult
Age Distribution
Blood Pressure Determination - methods
Coal Mining - manpower
Humans
Hypertension - diagnosis - epidemiology
Male
Middle Aged
Occupational Health - standards - statistics & numerical data
Occupational Health Services - methods - statistics & numerical data
Occupations
Risk factors
Siberia - epidemiology
Workplace - standards
Abstract
The analysis of age features of prevalence of an arterial hypertensia in the basic professional groups of the coal-mining enterprises was carried out. In total 1575 workers of collieries and cuts of Kuzbas united in 9 professional groups participated in the research. The results of research demonstrated the distinctions of age structure in the professional groups, testifying about expressed professional senescence among workers of mines, which reveals itself in the decrease in relative density of persons of 50+ years. In these groups with the expressed professional senescence the decrease in relative density of persons with an arterial hypertensia--so-called effect of the "healthy worker", in turn, is observed.
PubMed ID
22550882 View in PubMed
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359 records – page 1 of 36.