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89 records – page 1 of 9.

Cancer in asbestos-mining and other areas of Quebec.

https://arctichealth.org/en/permalink/ahliterature249536
Source
J Natl Cancer Inst. 1977 Oct;59(4):1139-45
Publication Type
Article
Date
Oct-1977
Author
S. Graham
M. Blanchet
T. Rohrer
Source
J Natl Cancer Inst. 1977 Oct;59(4):1139-45
Date
Oct-1977
Language
English
Publication Type
Article
Keywords
Asbestos - adverse effects
Epidemiologic Methods
Female
Humans
Intestinal Neoplasms - etiology
Intestine, Small
Lip Neoplasms - etiology
Male
Mining
Neoplasms - epidemiology - etiology
New York
Occupational Diseases - epidemiology - etiology
Peritoneal Neoplasms - etiology
Pleural Neoplasms - etiology
Quebec
Risk
Rural Population
Salivary Gland Neoplasms - etiology
Tongue Neoplasms - etiology
Urban Population
Abstract
Employing incidence data from the Quebec Tumor Registry, we examined the relative risks of cancer of all sites for the years 1969-73 in the asbestos-mining, rural, and metropolitan counties of Quebec Province, Canada. Generally, rates for males exceeded those for females, and the relative risks in the asbestos-mining counties for 7-10 different sites of cancer, all of low incidence, were from 1.50 to 8.08 times those of other rural counties of the Province for both sexes. Metropolitan counties exhibited equally high risk for many of these sites. We discovered higher risks among males in asbestos-mining counties for cancer of the pleura, peritoneum, lip, tongue, salivary gland, mouth, and small intestine and higher risks among females for cancer of the pleura, lip, kidney, salivary gland, and for melanoma. Because of the likelihood of a long latent period for asbestos-related cancers, the risks we observed were possibly the product of since-altered occupational and environmental conditions existing 20-30 years ago in the asbestos-mining areas. The similarities in risks for most cancers in asbestos-mining and urban areas were noteworthy.
PubMed ID
903992 View in PubMed
Less detail

Chemical characterization of asbestos body cores by electron microprobe analysis.

https://arctichealth.org/en/permalink/ahliterature255338
Source
J Histochem Cytochem. 1972 Sep;20(9):723-34
Publication Type
Article
Date
Sep-1972

Chrysotile, tremolite, and mesothelioma.

https://arctichealth.org/en/permalink/ahliterature215812
Source
Science. 1995 Feb 10;267(5199):776-7
Publication Type
Article
Date
Feb-10-1995

Clinical measurement in Quebec chrysotile miners: use for future protection of workers.

https://arctichealth.org/en/permalink/ahliterature247778
Source
Ann N Y Acad Sci. 1979;330:23-9
Publication Type
Article
Date
1979
Author
M R Becklake
Source
Ann N Y Acad Sci. 1979;330:23-9
Date
1979
Language
English
Publication Type
Article
Keywords
Asbestos - adverse effects
Asbestosis - etiology - prevention & control
Humans
Male
Mining
Occupational Diseases - etiology - prevention & control
Public Health
Quebec
Abstract
There is a relationship between dust exposure, on the one hand, and serious disease and death, on the other, in chrysotile asbestos mine and mill workers of Quebec. Studies in current working populations indicate that prevalence of abnormality increases with increasing exposure. However, the relationship is weak and offers only a partial explanation of between-subject variability. In addition, there is no certain way to detect or predict change. Because of the relative nonspecificity of the health measurements examined and their poor relationship to exposure, control should be based on environmental monitoring, with biologic monitoring considered in a complementary role. This leaves the clinician with the dilemma of how best to advise the worker in whom questionable changes have been detected. At present, there appears little doubt that the decision must remain essentially clinical, based, on one hand, on all available information about the man, his job, and the plant or mine in which he works, from which an estimate of likely outcome must be made, and, on the other hand, on the social and human factors concerned, including the fact that removal from exposure does not necessarily prevent the appearance of abnormality.
PubMed ID
294176 View in PubMed
Less detail

[Clinico-epidemiological analysis of the results of the Mantoux reaction with 1:2000 dilution in workers of the anthracite mines in the Artemovsk region]

https://arctichealth.org/en/permalink/ahliterature70161
Source
Probl Tuberk. 1968;46(8):10-4
Publication Type
Article
Date
1968

The combination of effects on lung cancer of cigarette smoking and exposure in quebec chrysotile miners and millers.

https://arctichealth.org/en/permalink/ahliterature190229
Source
Ann Occup Hyg. 2002 Jan;46(1):5-13
Publication Type
Article
Date
Jan-2002
Author
F D K Liddell
B G Armstrong
Author Affiliation
Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada.
Source
Ann Occup Hyg. 2002 Jan;46(1):5-13
Date
Jan-2002
Language
English
Publication Type
Article
Keywords
Air Pollutants, Occupational - adverse effects
Asbestos, Serpentine - adverse effects
Causality
Cause of Death
Cohort Studies
Humans
Lung Neoplasms - etiology
Male
Mining
Models, Statistical
Quebec
Risk assessment
Smoking - adverse effects
Abstract
Although it is well known that both cigarette smoke and microscopic airborne asbestos fibres can cause lung cancer, evidence as to how these two agents combine is nebulous. Many workers have believed in the multiplicative theory, whereby asbestos increases the risk in proportion to the risk from other causes. However, evidence against this theory is mounting: a recent review concluded that the multiplicative hypothesis was untenable, and that the relative risk of lung cancer from asbestos exposure was about twice as high in non-smokers as in smokers, a finding largely independent of type of asbestos fibre. The criteria for entry to the current study were met by 7279 men in the 1891-1920 birth cohort of Quebec chrysotile miners and millers. The data consisted of date of birth, place of employment, smoking habit, asbestos exposure accumulated to age 55 and, for those 5527 who died between 1950 and June 1992, date and cause of death; 533 of the deaths were from lung cancer. For the principal analyses, ex-smokers were excluded from the study cohort, which comprised 5888 men, of whom 473 died of lung cancer. The conventional form of analysis is simply of the double dichotomy: non-smokers of cigarettes, 'unexposed' and exposed; all others, 'unexposed' and exposed. The respective standardized lung cancer mortality ratios (SMRs) were 0.29 and 0.62; and 1.37 and 1.72. Thus, the differences in relative risk, due to exposure, were closely similar, 0.33 and 0.35. On the other hand, the effects of asbestos measured by the corresponding ratios, 2.12 and 1.25, did differ, being 1.7 times as high in non-smokers as in others. The principal analysis was much more penetrating: the method was to fit models to a 'disaggregated' 6 x 10 array, by smoking habit (excluding ex-smokers) and asbestos exposure, of lung cancer SMRs. Both linear and log-linear models were fitted: the former included the additive and linear-multiplicative; the latter embraced the more conventional multiplicative form. The additive model fitted much the best. The fit of each multiplicative model was improved by the introduction of an interaction term that implied a less than multiplicative relationship. Thus smoking and exposure to chrysotile appear to have acted independently in causing lung cancer, with 10 cigarettes a day having an effect roughly equivalent to exposure amounting to 700 million particles per cubic foot x years. The refutation of the multiplicative hypothesis in these data reinforces its inapplicability in general; but the additive hypothesis is not generally applicable either. Indeed, there seems to be no good reason to believe that interactions conform to any simple theory. The implications are important.
PubMed ID
12005133 View in PubMed
Less detail

Comment on McDonald et al's study on mortality in asbestos industry.

https://arctichealth.org/en/permalink/ahliterature255574
Source
Arch Environ Health. 1972 Apr;24(4):294-5
Publication Type
Article
Date
Apr-1972

[Comparative evaluation of the health status of miners engaged in mechanical and hydraulic extraction of coal in the Kuznetsk basin].

https://arctichealth.org/en/permalink/ahliterature255353
Source
Gig Tr Prof Zabol. 1972 Sep;16(9):51-2
Publication Type
Article
Date
Sep-1972
Author
A B Kogan
T E Schukina
I Iu Plotnitskii
Source
Gig Tr Prof Zabol. 1972 Sep;16(9):51-2
Date
Sep-1972
Language
Russian
Publication Type
Article
Keywords
Coal Mining
Humans
Occupational Diseases - diagnosis
Occupational Medicine
Siberia
PubMed ID
4656345 View in PubMed
Less detail

89 records – page 1 of 9.