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172 records – page 1 of 18.

[1967-82, an evaluation of the Swedish experience with maintenance methadone therapy of morphine addicts].

https://arctichealth.org/en/permalink/ahliterature242669
Source
Minerva Med. 1982 Dec 8;73(47):3353-8
Publication Type
Article
Date
Dec-8-1982
Author
M. Scordato
Source
Minerva Med. 1982 Dec 8;73(47):3353-8
Date
Dec-8-1982
Language
Italian
Publication Type
Article
Keywords
Follow-Up Studies
Health services needs and demand
Humans
Methadone - therapeutic use
Morphine Dependence - drug therapy - rehabilitation
Statistics as Topic
Sweden
Abstract
Since 1967, 170 heroin addicts have used methadone-based maintenance therapy. The experimental programme, confined to the Uppsala Psychiatric Clinic, followed the Dole-Nyswander method. Evaluation of the results shows the therapy to be successful in reducing mortality and permanent disability rates in heroin users. In addition it was found that addicts included in the programme were more likely to achieve complete social rehabilitation. In spite of much criticism, the experiment was sufficiently successful to justify its continuation, though still within the limits and along the lines adopted in the past.
PubMed ID
7177464 View in PubMed
Less detail

Abstinence fear in methadone maintenance withdrawal: a possible obstacle for getting off methadone.

https://arctichealth.org/en/permalink/ahliterature208577
Source
Subst Use Misuse. 1997 May;32(6):779-92
Publication Type
Article
Date
May-1997
Author
C. Eklund
A J Hiltunen
L. Melin
S. Borg
Author Affiliation
Department of Clinical Psychology, University of Uppsala, Sweden.
Source
Subst Use Misuse. 1997 May;32(6):779-92
Date
May-1997
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Fear
Female
Heroin Dependence - psychology - rehabilitation
Humans
Male
Methadone - therapeutic use
Psychometrics
Substance Withdrawal Syndrome - psychology
Sweden
Abstract
The present study attempts to shed light on methadone maintenance patients expectations regarding withdrawal symptoms during voluntary methadone detoxification. The study includes two groups of subjects; one group who have tried on their own initiative to terminate their methadone maintenance treatment (Group 1) and one group that contains rehabilitated patients who have not tried to quit using methadone (Group 2). Two main results have emerged. Group 1 has negative expectations beforehand about the intensity of withdrawal which significantly exceed the later, actual experience. Group 2 has negative expectations about the intensity of withdrawal that significantly exceed the negative expectations of Group 1. The clinical implications of these results are discussed.
PubMed ID
9178443 View in PubMed
Less detail

Alberta gets a second methadone clinic.

https://arctichealth.org/en/permalink/ahliterature182009
Source
Can HIV AIDS Policy Law Rev. 2002 Dec;7(2-3):36-7
Publication Type
Article
Date
Dec-2002

The allocation of drug addicts to different types of treatment. An evaluation and a two-year follow-up.

https://arctichealth.org/en/permalink/ahliterature73904
Source
Am J Drug Alcohol Abuse. 1989;15(1):41-53
Publication Type
Article
Date
1989
Author
E. Segest
O. Mygind
H. Bay
Author Affiliation
Office of the Commissioner of Health, Copenhagen, Denmark.
Source
Am J Drug Alcohol Abuse. 1989;15(1):41-53
Date
1989
Language
English
Publication Type
Article
Keywords
Adult
Crime
Denmark
Female
Follow-Up Studies
Health Policy
Humans
Male
Methadone - therapeutic use
Patient compliance
Referral and Consultation
Research Support, Non-U.S. Gov't
Substance-Related Disorders - mortality - rehabilitation - therapy
Abstract
In Denmark the official aim has been to reduce methadone treatment, even though no effort is made to directly forbid this therapy. A multiprofessional committee was established to regulate and limit methadone treatment. There were no specific guidelines for what type of drug addict should be treated with methadone. We found that allocation for the Regional Narcotic Committee of the Municipality of Copenhagen during 1982-1984 did not serve the desires of the addicts because only 41% followed it. Allocation also did not follow the principles of research in this field. In a 2-year follow-up investigation we found that drug addicts had a mortality rate of 6.3/year, rising criminality (significant), and falling availability to the labor market (nonsignificant). We therefore came to the conclusion that the efforts of the committee did not improve the conditions of drug addicts. Only those drug addicts who had been under almost constant methadone treatment had a low lethality and a falling number of criminal convictions (significant). Finally, it is concluded that limited research within this field prevents more specific treatment and improved use of financial resources.
PubMed ID
2923110 View in PubMed
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An 18-year follow-up of patients admitted to methadone treatment for the first time.

https://arctichealth.org/en/permalink/ahliterature90117
Source
J Addict Dis. 2009;28(1):39-52
Publication Type
Article
Date
2009
Author
Davstad Ingrid
Stenbacka Marlene
Leifman Anders
Romelsjö Anders
Author Affiliation
Stockholm Addiction Centre, Karolinska Hospital, Stockholm, Sweden. ingrid.davstad@sll.se
Source
J Addict Dis. 2009;28(1):39-52
Date
2009
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Cause of Death
Criminology - statistics & numerical data
Diagnosis, Dual (Psychiatry)
Female
Follow-Up Studies
HIV Infections - epidemiology
Humans
Incidence
Male
Mental Disorders - epidemiology
Methadone - therapeutic use
Mortality
Narcotics - therapeutic use
Opioid-Related Disorders - epidemiology - psychology - rehabilitation - virology
Registries
Regression Analysis
Substance Abuse Treatment Centers - methods - statistics & numerical data
Sweden - epidemiology
Treatment Outcome
Young Adult
Abstract
An 18-year addiction career, 1985-2003, for 157 heroin dependent subjects (73% men; 49% human immunodeficiency virus seropositive) admitted for the first time to Stockholm's Methadone Maintenance Treatment program during 1989 to 1991 was analyzed with data from seven official registers and patient records. Regression analyses and incidence rates for various outcomes were calculated for subjects in first methadone maintenance treatment at the end of the observation period, discharged from first methadone maintenance treatment, in second methadone maintenance treatment, and discharged from second methadone maintenance treatment. Being human immunodeficiency virus positive (HR = 3.8), lodging (HR = 1.9) and prison sentence (HR = 1.7) predicted mortality for the 45% deceased. Approximately 70% of living subjects participated in methadone maintenance treatment at some period each year. Subjects in first or second methadone maintenance treatment had less criminality and had spent more time in methadone maintenance treatment (70% to 100%) than those discharged from first or from second methadone maintenance treatment (50%). Efforts and interventions should be intensified to increase time in treatment also for those with high problem severity.
PubMed ID
19197594 View in PubMed
Less detail

Antiretroviral adherence and HIV treatment outcomes among HIV/HCV co-infected injection drug users: the role of methadone maintenance therapy.

https://arctichealth.org/en/permalink/ahliterature170216
Source
Drug Alcohol Depend. 2006 Sep 15;84(2):188-94
Publication Type
Article
Date
Sep-15-2006
Author
Anita Palepu
Mark W Tyndall
Ruth Joy
Thomas Kerr
Evan Wood
Natasha Press
Robert S Hogg
Julio S G Montaner
Author Affiliation
Centre for Health Evaluation and Outcome Sciences, St. Paul's Hospital, University of British Columbia, BC, Canada. anita@hivnet.ubc.ca
Source
Drug Alcohol Depend. 2006 Sep 15;84(2):188-94
Date
Sep-15-2006
Language
English
Publication Type
Article
Keywords
Adult
Anti-Retroviral Agents - blood - therapeutic use
British Columbia - epidemiology
Cohort Studies
Comorbidity
Demography
Female
Follow-Up Studies
HIV Infections - drug therapy - epidemiology
Hepatitis C - epidemiology
Humans
Male
Methadone - therapeutic use
Narcotics - therapeutic use
Patient Compliance - statistics & numerical data
Prevalence
Questionnaires
Risk-Taking
Substance Abuse, Intravenous - epidemiology - rehabilitation
Abstract
We examined the association of methadone maintenance therapy (MMT) with highly active antiretroviral therapy (HAART) adherence and HIV treatment outcomes among a cohort of HIV/HCV co-infected injection drug users (IDUs).
We obtained demographic, drug use, and addiction care history from the Vancouver Injection Drug User Study (VIDUS), which is an open cohort study of IDUs. The questionnaires were longitudinally linked to the British Columbia HIV/AIDS Drug Treatment Program to obtain HAART adherence and HIV treatment outcome data. There were 278 VIDUS participants who accessed HAART from August 1, 1996 to November 24, 2003. We constructed longitudinal logistic models using generalized estimating equations to examine the independent associations between methadone maintenance therapy and the following outcomes: HAART adherence; plasma HIV-1 RNA suppression; and CD4 cell rise of 100cells/mm(3).
Among participants who reported at least weekly heroin use, MMT was independently associated with lower odds of subsequent weekly heroin use during the follow-up period (adjusted odds ratio; 95% confidence interval [AOR; 95% CI]: 0.24; 0.14-0.40). We also found that MMT was positively associated with adherence (AOR 1.52; 95% CI 1.16-2.00), HIV-1 RNA suppression (AOR 1.34; 95% CI 1.00-1.79), and CD4 cell count rise (AOR 1.58; 95% CI 1.26-1.99).
Among HIV/HCV co-infected IDUs on HAART, enrollment in MMT was associated with reduced heroin use, and improved adherence, HIV-1 RNA suppression and CD4 cell count response. Integrating opiate addiction care and HIV care may provide improved health outcomes for this vulnerable population and should be further explored.
PubMed ID
16542797 View in PubMed
Less detail
Source
Tidsskr Nor Laegeforen. 2009 Nov 5;129(21):2260-1
Publication Type
Article
Date
Nov-5-2009
Author
Bengt Eide-Olsen
Author Affiliation
Stiftelsen Bergensklinikkene Hjellestad, Flyen 30, 5259 Hjellestad, Norway. eide_olsen_bengt@hotmail.com
Source
Tidsskr Nor Laegeforen. 2009 Nov 5;129(21):2260-1
Date
Nov-5-2009
Language
Norwegian
Publication Type
Article
Keywords
Buprenorphine - therapeutic use
Health Policy
Humans
Methadone - therapeutic use
Narcotics - therapeutic use
Norway
Opioid-Related Disorders - rehabilitation
Patient Rights
PubMed ID
19898579 View in PubMed
Less detail

Appreciating the user's perspective: listening to the "methadonians".

https://arctichealth.org/en/permalink/ahliterature189776
Source
Subst Use Misuse. 2002 Mar;37(4):565-70
Publication Type
Article
Date
Mar-2002
Author
Michael Montagne
Author Affiliation
Massachusetts College of Pharmacy & Health Sciences, Boston 02115, USA. mmontagne@mcp.edu
Source
Subst Use Misuse. 2002 Mar;37(4):565-70
Date
Mar-2002
Language
English
Publication Type
Article
Keywords
Canada
Humans
Methadone - therapeutic use
Opioid-Related Disorders - rehabilitation
Patient Participation
Substance Abuse Treatment Centers
Abstract
Researchers have long neglected the user's perspective and experiences in assessing drug effects and drug use. With increased interest in Canada directed at prescribing heroin in place of methadone, researchers took the relatively unique approach of gathering data and information from methadone users to determine their views and experiences with methadone programs and alternative treatment choices. The results of that research portrayed very interesting and useful notions of users regarding methadone maintenance and the prescribing of heroin.
Notes
Comment On: Subst Use Misuse. 2002 Mar;37(4):495-52212064431
PubMed ID
12064438 View in PubMed
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The Beck Depression Inventory in patients undergoing opiate agonist maintenance treatment.

https://arctichealth.org/en/permalink/ahliterature79535
Source
Br J Clin Psychol. 2006 Sep;45(Pt 3):417-25
Publication Type
Article
Date
Sep-2006
Author
Hesse Morten
Author Affiliation
Centre for Alcohol and Drug Research, Aarhus University, Copenhagen, Denmark. mortenhesse@crf.dk
Source
Br J Clin Psychol. 2006 Sep;45(Pt 3):417-25
Date
Sep-2006
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Alcoholism - psychology - rehabilitation
Buprenorphine - therapeutic use
Comorbidity
Denmark
Depressive Disorder - diagnosis - psychology
Female
Follow-Up Studies
Humans
Male
Methadone - therapeutic use
Middle Aged
Narcotics - therapeutic use
Opioid-Related Disorders - psychology - rehabilitation
Outcome Assessment (Health Care) - statistics & numerical data
Personality Inventory - statistics & numerical data
Prognosis
Prospective Studies
Psychometrics - statistics & numerical data
Reproducibility of Results
Street Drugs
Substance Abuse Treatment Centers
Treatment Refusal - psychology
Abstract
BACKGROUND AND OBJECTIVES: The Beck Depression Inventory (BDI) is a widely used measure of depression severity in both research and clinical contexts. This study aimed at assessing its stability and associations with ongoing drug use in a sample of patients in opiate agonist maintenance treatment who were not abstinent from illicit drugs. DESIGN AND METHOD: The study was a prospective, naturalistic study. Subjects in enhanced or standard psychosocial services along with opiate agonist maintenance treatment were administered the BDI and the European Addiction Severity Index (EuropASI) twice by research technicians, approximately 2 weeks after intake and at 18 months follow-up. FINDINGS: There were rather small mean changes from intake to follow-up in the BDI, and mean-level stability in subjects was rather high as evidenced by a high intra-class correlation between intake score and follow-up score. The stability of the BDI was reduced at high levels of drug use severity at intake, and BDI was a moderate predictor of drug use severity at follow-up. CONCLUSIONS: The BDI measures a construct that is both stable and of predictive validity in a sample of non-abstinent opiate agonist maintenance patients, although very severe drug use at baseline appeared to reduce the stability of the BDI.
PubMed ID
17147106 View in PubMed
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172 records – page 1 of 18.