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An evaluation of measles serodiagnosis during an outbreak in a vaccinated community.

https://arctichealth.org/en/permalink/ahliterature232723
Source
Clin Invest Med. 1988 Aug;11(4):304-9
Publication Type
Article
Date
Aug-1988
Author
L. Sekla
W. Stackiw
G. Eibisch
I. Johnson
Author Affiliation
Cadham Provincial Laboratory, Winnipeg, Manitoba.
Source
Clin Invest Med. 1988 Aug;11(4):304-9
Date
Aug-1988
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Antibodies, Viral - analysis
Child
Child, Preschool
Disease Outbreaks
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin M - analysis
Infant
Male
Manitoba
Measles - diagnosis - epidemiology - immunology
Measles Vaccine - immunology
Measles virus - immunology
Serologic Tests
Abstract
During an epidemic of measles in a vaccinated community, five serodiagnostic tests were performed on 67 persons on whom clinical and epidemiological data were available. The test found most suitable for a rapid diagnosis of measles infection was an Enzyme Linked Immuno Sorbent Assay for the detection of specific IgM antibodies. Only one false negative IgM was recorded. In a group of 45 persons who fulfilled the clinical definition of measles, specific IgM antibodies were detected in the acute phase serum of only 30 (66.6%), of whom 17 were vaccinated. When the convalescent sera were tested, specific IgM antibodies were detected in 25 of the 28 (89.2%) vaccinated, and in 17 of the 17 (100%) non vaccinated clinical cases. A convalescent blood should be tested in persons with a rash illness and no IgM antibodies in the acute phase serum. There were individual variations in the time of appearance of IgM. On the day of onset of rash, IgM antibodies were detected in 7 of the 12 (58.3%). A history of prior vaccination is not always associated with immunity nor with the presence of specific antibodies.
PubMed ID
3168353 View in PubMed
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[Changes in measles, mumps and rubella (MMR) immunity until the year of 2002 after the introduction of MMR vaccination]

https://arctichealth.org/en/permalink/ahliterature36645
Source
Ugeskr Laeger. 1992 Jul 13;154(29):2014-8
Publication Type
Article
Date
Jul-13-1992
Author
T. Rønne
H. Trier
Author Affiliation
Epidemiologisk afdeling, Statens Seruminstitut, København.
Source
Ugeskr Laeger. 1992 Jul 13;154(29):2014-8
Date
Jul-13-1992
Language
Danish
Publication Type
Article
Keywords
Adolescent
Antibodies, Viral - analysis - biosynthesis
Child
Child, Preschool
Denmark
English Abstract
Humans
Immunization, Secondary
Measles Vaccine - administration & dosage - adverse effects - immunology
Measles virus - immunology
Models, Biological
Mumps Vaccine - administration & dosage - adverse effects - immunology
Mumps virus - immunology
Prognosis
Rubella Vaccine - administration & dosage - adverse effects - immunology
Rubella virus - immunology
Abstract
In order to decide whether vaccination for measles, mumps and rubella should be introduced at the age of five years, calculations of the immunities in various age groups were performed until the year 2002 with and without vaccination at the age of five years. These calculations are based on the knowledge of immunity in the various age groups before the MMR vaccination programme was instituted in 1987 and knowledge of the compliance with vaccination obtained to date. Future predictions reveal that it is of decisive significance that compliance with vaccination among 12-year-olds is increased as rapidly as possible to 0.7 and to 0.8 in the subsequent year, if the level of immunity present prior to institution of the vaccination programme is to be maintained. The second vaccination given at a shorter interval after the first would prevent about 150 cases of illness in all per annum among 6-12 years-old. However, this should not be introduced at the expense of vaccination at the age of 12 years, which should be continued for at least 10-15 years yet. Possible abandoning of vaccination at the age of 12 years 10-15 years hence presupposes that adequate numbers of the children have been vaccinated twice at an early age and that it is sufficiently certain that secondary failure of vaccination does not occur to any significant extent.
PubMed ID
1509567 View in PubMed
Less detail

[Characteristics of the immune response of children in the Arctic to live measles vaccine]

https://arctichealth.org/en/permalink/ahliterature5881
Source
Zh Mikrobiol Epidemiol Immunobiol. 1987 Dec;(12):51-3
Publication Type
Article
Date
Dec-1987
Author
L V Anpilogova
A V Dubov
V F Popov
T N Iunasova
A P Leiko
Source
Zh Mikrobiol Epidemiol Immunobiol. 1987 Dec;(12):51-3
Date
Dec-1987
Language
Russian
Publication Type
Article
Keywords
Antibodies, Viral - analysis
Arctic Regions
Child, Preschool
Cold Climate
Comparative Study
English Abstract
Humans
Infant
Measles Vaccine - immunology
Measles virus - immunology
USSR
Urban Population
Abstract
The intensity of immune response to live measles vaccine varies in children living in different climatic and geographical regions. The least intensive immunogenesis is registered in children living in the Arctic regions. The level of seroconversion in children living in these regions rises in response to measles vaccine containing a 10-fold amount of the virus per immunization dose.
PubMed ID
3445731 View in PubMed
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Confirmed interruption of indigenous measles transmission in Catalonia.

https://arctichealth.org/en/permalink/ahliterature186296
Source
Euro Surveill. 2001 Jul;6(7):113-7
Publication Type
Article
Date
Jul-2001
Author
L. Salleras
A. Domínguez
N. Torner
Author Affiliation
Department of Health and Social Security, Generalitat Catalonia, Barcelona, Spain.
Source
Euro Surveill. 2001 Jul;6(7):113-7
Date
Jul-2001
Language
English
Publication Type
Article
Keywords
Antibodies, Viral - blood
Humans
Immunization Programs
Immunoglobulin G - blood
Measles - epidemiology - prevention & control - transmission
Measles virus - immunology
Measles-Mumps-Rubella Vaccine - administration & dosage
Population Surveillance
Program Evaluation
Spain - epidemiology
Abstract
From November 1998 to December 2000, 84 suspected measles cases were reported in Catalonia (6 090 040 inhabitants). Of the 73 laboratory tested cases (87%), 20 showed IgM antibodies specific to measles and 3 were epidemiologically linked to a confirmed case. Among these 23 confirmed cases, 13 were indigenous, the last two cases reported dating back from June 1999 and July 2000. These results confirm the success of the measles elimination programme implemented in 1998 in Catalonia.
PubMed ID
12631955 View in PubMed
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Detection of acute measles infections by indirect and mu-capture enzyme immunoassays for immunoglobulin M antibodies and measles immunoglobulin G antibody avidity enzyme immunoassay.

https://arctichealth.org/en/permalink/ahliterature59314
Source
J Med Virol. 1995 Mar;45(3):306-11
Publication Type
Article
Date
Mar-1995
Author
H. Tuokko
Author Affiliation
Department of Medical Microbiology, University of Oulu, Finland.
Source
J Med Virol. 1995 Mar;45(3):306-11
Date
Mar-1995
Language
English
Publication Type
Article
Keywords
Acute Disease
Animals
Antibodies, Viral - blood
Antibody Affinity
Blood Donors
Comparative Study
Humans
Immunoenzyme Techniques
Immunoglobulin G - blood
Immunoglobulin M - blood
Infant
Measles - diagnosis - immunology
Measles virus - immunology
Abstract
An avidity test for measles IgG was developed and applied to the study of IgG immunoglobulin maturation kinetics in follow-up sera from 12 patients with known acute primary and convalescent measles and sera from blood donors. The avidity of the IgG anti-measles responses was measured using the 8 M urea elution technique, the results being expressed as the percentage ratio between the test readings for eluted and noneluted samples. The IgG avidity results were compared with those of indirect and mu-capture IgM enzyme immunoassays. This test was capable of detecting low-avidity antibodies at the acute phase of measles up to 7 weeks, and increasing avidity through immunosaturation during the convalescent phase. The avidity in these samples did not reach the level found in the samples of the blood donors under the follow-up time. Although a limited number of serum samples was examined, the results suggest that the measles IgG avidity test is a powerful tool for differentiating primary measles infection from the convalescent phase.
PubMed ID
7775952 View in PubMed
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[Effectiveness of measles immunoprophylaxis and the criteria for assessing its possible elimination]

https://arctichealth.org/en/permalink/ahliterature39089
Source
Zh Mikrobiol Epidemiol Immunobiol. 1986 Nov;(11):24-30
Publication Type
Article
Date
Nov-1986
Author
A A Sokhin
L I Sliusar'
S A Ignatov
L S Mekhova
Source
Zh Mikrobiol Epidemiol Immunobiol. 1986 Nov;(11):24-30
Date
Nov-1986
Language
Russian
Publication Type
Article
Keywords
Adult
Age Factors
Antibodies, Viral - analysis
Disease Reservoirs
English Abstract
Female
Humans
Immunity
Immunization, Secondary
Infant
Infant, Newborn
Measles - epidemiology - immunology - prevention & control
Measles Vaccine - immunology
Measles virus - immunology
Postpartum Period
Pregnancy
Ukraine
Abstract
The study of measles morbidity in Donetsk Province in 1960-1984 and the study of antimeasles immunity in different groups of the population have shown that the problem of the liquidation of measles cannot be solved by immunizing the population in a single administration of the vaccine. To enhance the effectiveness of the immunoprophylaxis of measles and its influence on the epidemic process, a number of problems must be solved with the aim to improve the quality of the vaccine, especially its thermal stability, to establish the possibility of shifting the beginning of immunization from 15-17 months to 12 months of age, to increase the coverage of children with immunization against measles by decreasing the number of groundless exemptions from immunization and by immunizing children in risk groups according to individual schedules and dosage, to carry out selectively the booster immunization of persons who have lost their postvaccinal immunity, as revealed by laboratory test, or in whom such loss may be supposed, to introduce the objective method (indirect hemagglutination test) for controlling the state of immunity among different groups of the population into laboratory practice at sanitary and epidemiological stations. As to the possibility of the liquidation of measles, the statement of this problem is correct, but for its solution a complex of additional prophylactic and epidemic-control measures should be taken.
PubMed ID
3799112 View in PubMed
Less detail

[Epidemiologic characteristics of measles during a period of mass active immunization]

https://arctichealth.org/en/permalink/ahliterature40982
Source
Zh Mikrobiol Epidemiol Immunobiol. 1980 Jul;(7):109-10
Publication Type
Article
Date
Jul-1980

59 records – page 1 of 6.