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Ascorbic acid supplements and kidney stone incidence among men: a prospective study.

https://arctichealth.org/en/permalink/ahliterature116587
Source
JAMA Intern Med. 2013 Mar 11;173(5):386-8
Publication Type
Article
Date
Mar-11-2013
Author
Laura D K Thomas
Carl-Gustaf Elinder
Hans-Göran Tiselius
Alicja Wolk
Agneta Akesson
Source
JAMA Intern Med. 2013 Mar 11;173(5):386-8
Date
Mar-11-2013
Language
English
Publication Type
Article
Keywords
Aged
Ascorbic Acid - administration & dosage - adverse effects - pharmacokinetics
Calcium Oxalate - metabolism
Cohort Studies
Dietary Supplements - adverse effects
Dose-Response Relationship, Drug
Humans
Incidence
Kidney Calculi - chemically induced - epidemiology - metabolism
Male
Middle Aged
Proportional Hazards Models
Prospective Studies
Risk assessment
Sweden
Vitamins - administration & dosage - adverse effects - pharmacokinetics
Notes
Comment In: JAMA Intern Med. 2013 Jul 22;173(14):138423877084
Comment In: JAMA Intern Med. 2013 Jul 22;173(14):138423877085
Comment In: Nat Rev Urol. 2013 Apr;10(4):18423419496
Comment In: JAMA Intern Med. 2013 Mar 11;173(5):375-9423381657
Comment In: J Urol. 2013 Oct;190(4):1268-924029326
Comment In: Nat Rev Nephrol. 2013 Apr;9(4):18723419349
PubMed ID
23381591 View in PubMed
Less detail

Dietary cadmium exposure and kidney stone incidence: a population-based prospective cohort study of men & women.

https://arctichealth.org/en/permalink/ahliterature112476
Source
Environ Int. 2013 Sep;59:148-51
Publication Type
Article
Date
Sep-2013
Author
Laura D K Thomas
Carl-Gustaf Elinder
Hans-Göran Tiselius
Alicja Wolk
Agneta Akesson
Author Affiliation
Institute of Environmental Medicine, Unit of Nutritional Epidemiology, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden.
Source
Environ Int. 2013 Sep;59:148-51
Date
Sep-2013
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Cadmium - adverse effects
Cohort Studies
Diet - adverse effects
Female
Humans
Incidence
Kidney Calculi - chemically induced - epidemiology
Life Style
Male
Middle Aged
Prevalence
Prospective Studies
Questionnaires
Risk
Risk factors
Sweden - epidemiology
Abstract
Cadmium exposure is associated with increased urinary calcium excretion. Hypercalciuria is recognised as a major risk factor for kidney stone formation. Increased prevalence of kidney stones among those occupationally exposed to cadmium has previously been suggested. Food is the main source of cadmium exposure in the general population with tobacco representing an important additional source among smokers. We aimed to assess the association between dietary cadmium exposure and kidney stone incidence in two large population-based, prospective cohorts of men (Cohort of Swedish Men; COSM) and women (The Swedish Mammography Cohort; SMC). Those with a history of kidney stones were excluded. At baseline 1997, men (45-79yrs) and women (48 to 83yrs), completed a self-administered questionnaire on diet and lifestyle. During 12years of follow-up, we ascertained 707 cases of kidney stones in men and 290 in women through linkage of the cohorts to the national inpatient and outpatient registers. Individual dietary cadmium exposure was estimated using dietary data and concentrations of cadmium in food. Hazard ratios (HR) were calculated using the Cox proportional hazards regression models with adjustment for other risk factors. Estimated dietary cadmium exposure was not associated with increased kidney stone incidence among men HR 0.97 (95% confidence interval (CI): 0.77-1.23) or women HR 0.99 (95% CI: 0.89-1.43), comparing the highest tertile with the lowest. In conclusion, our results do not support a strong association between dietary cadmium and kidney stone risk at the exposure levels seen in the general population.
PubMed ID
23827660 View in PubMed
Less detail

Incidence of renal stones among cadmium exposed battery workers.

https://arctichealth.org/en/permalink/ahliterature67778
Source
Br J Ind Med. 1993 Jul;50(7):598-602
Publication Type
Article
Date
Jul-1993
Author
L. Järup
C G Elinder
Author Affiliation
Department of Occupational Medicine, Karolinska Hospital, Sweden.
Source
Br J Ind Med. 1993 Jul;50(7):598-602
Date
Jul-1993
Language
English
Publication Type
Article
Keywords
Age Factors
Air - analysis
Cadmium - adverse effects
Cohort Studies
Dose-Response Relationship, Drug
Female
Humans
Incidence
Industry
Kidney Calculi - chemically induced - epidemiology
Male
Occupational Diseases - chemically induced - epidemiology
Occupational Exposure - adverse effects
Sweden - epidemiology
Time Factors
Abstract
The health effects of occupational exposure to cadmium were studied in a group of 902 workers employed for at least one year in a Swedish battery factory between 1931 and 1982. Data on air cadmium concentrations for different periods were combined with company employment records to obtain individual cumulative exposure estimates. A questionnaire including questions on the occurrence of kidney stones was sent to all 601 living workers and to the next of kin of 267 of the deceased workers. The response rate was 88%. 73 workers reported renal calculi that appeared after initial employment. A dose-response relation was found between cumulative exposure to cadmium and age standardised cumulative incidence. Incidence rate ratios (IRRs) were then computed for three exposure categories ( or = 34 micrograms/mmole creatinine)--that is, a prevalence of 39%. There was also an indication of a steeper dose-response relation among workers with tubular proteinuria.
PubMed ID
8343420 View in PubMed
Less detail

More evidence regarding vitamin C and kidney stone risk.

https://arctichealth.org/en/permalink/ahliterature104569
Source
Mayo Clin Health Lett. 2013 May;31(5):4
Publication Type
Article
Date
May-2013