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Canadian home total parenteral nutrition registry: preliminary data on the patient population.

https://arctichealth.org/en/permalink/ahliterature160745
Source
Can J Gastroenterol. 2007 Oct;21(10):643-8
Publication Type
Article
Date
Oct-2007
Author
Maitreyi Raman
Leah Gramlich
Scott Whittaker
Johane P Allard
Author Affiliation
University Health Network, Toronto, Canada.
Source
Can J Gastroenterol. 2007 Oct;21(10):643-8
Date
Oct-2007
Language
English
Publication Type
Article
Keywords
Adult
Aged
Bone Diseases - metabolism
Canada - epidemiology
Catheterization, Central Venous
Chronic Disease
Female
Humans
Intestinal Diseases - therapy
Liver - drug effects
Male
Middle Aged
Models, Statistical
Parenteral Nutrition, Home Total - adverse effects - statistics & numerical data
Prevalence
Quality of Life
Registries
Abstract
Long-term administration of home total parenteral nutrition (HTPN) has permitted patients with chronic intestinal failure to survive for prolonged periods of time. However, HTPN is associated with numerous complications, all of which increase morbidity and mortality. In Canada, a comprehensive review of the HTPN population has never been performed.
To report on the demographics, current HTPN practice and related complications in the Canadian HTPN population.
This was a cross-sectional study. Five HTPN programs in Canada participated. Patients' data were entered by the programs' TPN team into a Web site-based registry. A unique confidential record was created for each patient. Data were then downloaded into a Microsoft Excel (Microsoft Corp, USA) spreadsheet and imported into SPSS (SPSS Inc, USA) for statistical analysis.
One hundred fifty patients were entered into the registry (37.9% men and 62.1% women). The mean (+/- SD) age was 53.0+/-14 years and the duration requiring HTPN was 70.1+/-78.1 months. The mean body mass index before the onset of HTPN was 19.8+/-5.0 kg/m(2). The primary indication for HTPN was short bowel syndrome (60%) secondary to Crohn's disease (51.1%), followed by mesenteric ischemia (23.9%).
over one year, 62.7% of patients were hospitalized at least once, with 44% of hospitalizations related to TPN. In addition, 28.6% of patients had at least one catheter sepsis (double-lumen more than single-lumen; P=0.025) and 50% had at least one catheter change. Abnormal liver enzymes were documented in 27.4% of patients and metabolic bone disease in 60% of patients, and the mean Karnofsky score was 63.
In the present population sample, the data suggest that HTPN is associated with significant complications and health care utilization. These results support the use of a Canadian HTPN registry to better define the HTPN population, and to monitor complications for quality assurance and future research.
Notes
Cites: Health Technol Assess. 1997;1(1):i-iii, 1-599414540
Cites: Clin Infect Dis. 1998 Sep;27(3):500-39770147
Cites: Surgery. 1999 Jul;126(1):28-3410418589
Cites: Clin Nutr. 1999 Jun;18(3):131-310451478
Cites: Clin Nutr. 1999 Jun;18(3):135-4010451476
Cites: JPEN J Parenter Enteral Nutr. 2004 Nov-Dec;28(6):S39-7015568296
Cites: Nutrition. 2005 Feb;21(2):156-6015723743
Cites: Nutr Hosp. 2005 Jul-Aug;20(4):249-5316045126
Cites: Nutrition. 2006 Apr;22(4):355-6016413750
Cites: Eur J Clin Nutr. 2006 Jan;60(1):58-6116132056
Cites: JPEN J Parenter Enteral Nutr. 2006 May-Jun;30(3):215-2116639068
Cites: Nutr Hosp. 2006 Mar-Apr;21(2):127-3116734063
Cites: Clin Nutr. 2006 Aug;25(4):543-5316815601
Cites: JPEN J Parenter Enteral Nutr. 2006 Nov-Dec;30(6):492-617047173
Cites: Ann Intern Med. 2000 Apr 4;132(7):525-3210744588
Cites: Nutrition. 2000 Jul-Aug;16(7-8):625-810906576
Cites: Clin Nutr. 2002 Aug;21(4):289-9612135588
Cites: Am J Clin Nutr. 2002 Aug;76(2):482-812145026
Cites: Gastroenterology. 2003 May;124(6):1651-6112761723
Cites: J Bone Miner Res. 2003 Nov;18(11):1989-9414606511
Cites: Nutr Hosp. 2004 May-Jun;19(3):139-4315211721
Cites: J Lab Clin Med. 1982 Mar;99(3):317-247057059
Cites: Am J Med. 1982 Aug;73(2):199-2047114077
Cites: Ann Intern Med. 1983 Jun;98(6):910-46407375
Cites: Am J Clin Nutr. 1983 Aug;38(2):264-96410898
Cites: Acta Paediatr Scand. 1983 Sep;72(5):769-716416021
Cites: Lancet. 1986 Aug 16;2(8503):383-72874379
Cites: JPEN J Parenter Enteral Nutr. 1989 May-Jun;13(3):255-612503635
Cites: Arch Surg. 1990 Aug;125(8):990-22116119
Cites: JPEN J Parenter Enteral Nutr. 1991 Jul-Aug;15(4):384-931910101
Cites: Gastroenterology. 1993 Dec;105(6):1806-138253356
Cites: JAMA. 1994 May 25;271(20):1598-6018182812
Cites: Gastroenterology. 1995 Aug;109(2):355-657615183
Cites: Gut. 1997 Feb;40(2):218-229071935
PubMed ID
17948134 View in PubMed
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Home parenteral nutrition in Denmark in the period from 1996 to 2001.

https://arctichealth.org/en/permalink/ahliterature82375
Source
Scand J Gastroenterol. 2006 Apr;41(4):401-7
Publication Type
Article
Date
Apr-2006
Author
Ugur Asiya
Marashdeh Bilal H S
Gottschalck Ida
Brøbech Mortensen Per
Staun Michael
Bekker Jeppesen Palle
Author Affiliation
Department of Medicine CA-2121, Division of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Source
Scand J Gastroenterol. 2006 Apr;41(4):401-7
Date
Apr-2006
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Bacteremia - etiology
Catheterization - adverse effects
Denmark
Female
Home Care Services - utilization
Humans
Intestinal Diseases - therapy
Male
Middle Aged
Parenteral Nutrition - adverse effects - mortality - utilization
Retrospective Studies
Thrombosis - etiology
Abstract
OBJECTIVE: Home parenteral nutrition (HPN) has been provided to patients with intestinal failure in Denmark since 1970. The results of a national survey comprising a well-defined cohort receiving treatment with HPN in Denmark in the period from 1996 to the end of 2000 are presented, including data on incidence, prevalence, patient characteristics and complications of HPN treatment. MATERIAL AND METHODS: HPN was given to 202 patients (115 F, 87 M) 34% with short-bowel syndrome due to inflammatory bowel disease, 26% with cancer, 22% with surgical complications and 19% with other causes, for a total of 410 catheter years. RESULTS: At the end of 2000, the prevalence of HPN in Denmark was 19.2 per million, and the average annual incidence was 5.0 per million per year over the 5-year period. The incidence rates of catheter-related bacteraemia and thrombosis were 0.48 and 0.02 episodes per catheter year, respectively. The average catheter lasted 1.5 years. Venous inaccessibility was never encountered. The 5-year mortality was 25% (n = 51). However, only six deaths were related to HPN. Three patients died of HPN-related liver failure, two died of catheter-related sepsis and one patient died of an embolus induced by a catheter thrombus. CONCLUSIONS: Since its introduction in 1970 in Denmark, HPN has evolved from an experimental approach to a standardized therapy for patients with intestinal failure. Although HPN morbidity is increasing slightly compared with that reported in earlier surveys, HPN-induced mortality is still less than 1% per year.
PubMed ID
16635907 View in PubMed
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[Use of propionic-acidophilus milk in the complex treatment of children with staphylococcal intestinal dysbacteriosis]

https://arctichealth.org/en/permalink/ahliterature41651
Source
Pediatr Akus Ginekol. 1978 Jul-Aug;(4):5-6
Publication Type
Article

6 records – page 1 of 1.