Being born with low birth weight is a risk factor for psychiatric morbidity. Few longitudinal studies have included diagnostic assessment and followed subjects into adulthood.
To assess stability and change in psychiatric morbidity between adolescence and young adulthood in low birth weight subjects, and explore whether screening in adolescence can predict subsequent psychopathology in these groups.
Prospective geographically based follow-up study of two low birth weight groups and a control group born between 1986 and 1988, assessed at 14 (T1) and 20 (T2) years of age.
Thirty eight subjects born preterm with very low birth weight (VLBW: =1500g), 43 born at term but small for gestational age (SGA:
Being born with low birth weight may have an impact on different aspects of mental health, psychosocial functioning and well-being; however results from studies in young adulthood have so far yielded mixed findings. The aim of this study was to assess the long-term impact in young adulthood on self-reported mental health, health-related quality of life, self-esteem and social relations by investigating differences between two low birth weight groups and a control group.
In a follow-up at 20 years of age, 43 preterm VLBW (birth weight = 1500 g), 55 term SGA (birth weight
Cites: JAMA. 2000 Feb 2;283(5):625-3210665702
Cites: Arch Gen Psychiatry. 2012 Jun;69(6):E1-822660967
Cites: Early Hum Dev. 2001 Mar;61(2):97-11011223272
Cites: Lancet. 2001 May 26;357(9269):1641-311425366
Cites: Am J Psychiatry. 2001 Jul;158(7):1091-811431231
Cites: J Autism Dev Disord. 2001 Feb;31(1):5-1711439754
To examine psychiatric morbidity and overall functioning in adults born with low birth weight compared with normal birth weight controls at age 26 years and to study longitudinal trajectories of psychiatric morbidity from early adolescence to adulthood.
Prospective cohort study wherein 44 preterm very low birth weight (=1500 g), 64 term small for gestational age (SGA;
OBJECTIVE: The aim of this study was to explore psychiatric symptoms in low birth weight adolescents, and the usefulness of questionnaires compared with psychiatric interview. DESIGN/STUDY GROUPS: A population-based follow-up study of 56 very low birth weight (VLBW), 60 term small for gestational age (SGA) and 83 control adolescents at 14 years of age was made. OUTCOME MEASURES: The Achenbach System of Empirically Based Assessment (ASEBA) and the Strengths and Difficulties Questionnaire (SDQ) were rated by adolescents, parents and teachers. The results were compared with diagnostic assessment based on the semi-structured interview, Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS). RESULTS: VLBW adolescents had more psychiatric symptoms than controls, especially attention deficit, emotional, behavioural, social and also academic problems. Although less consistent, the SGA group had more emotional, conduct and attention deficit symptoms than controls. Results remained essentially the same when adolescents with low estimated IQ were excluded, and persisted after controlling for possible confounders. The sensitivity and specificity of ASEBA and SDQ differed between informants and groups. CONCLUSION: VLBW adolescents are at risk of developing psychiatric symptoms, and reduced social and academic skills by the age of 14. Term SGA adolescents may have discrete emotional, behavioural and attention deficit symptoms. ASEBA and SDQ provide a useful supplement to psychiatric interview.