The 1H NMR spectra of the lipid region of human plasma from healthy adults, neonates, and patients with malignant and nonmalignant tumors have been recorded on a JNM-GX400 FT spectrometer operating at 399.6 MHz for protons. The chemical shifts of methylene and methyl groups of plasma lipids were measured with respect to the higher field component of the methyl proton resonance of the lactate molecule. The results show that there are changes in the chemical shifts of the methylene proton resonances among the plasma from healthy adults, adults with tumors, and neonates. The shifts observed in the case of cancer patients and neonates are in the direction opposite to the shift measured from the plasma of healthy adults. Thus, the observed changes cannot be explained by the activity in the cell proliferation of tissues which is high in the cases of both healthy neonates and patients with malignant tumors, but they most probably reflect the different lipoprotein compositions of neonates, healthy adults, and adults with tumors.
Two epidemiologically unrelated outbreaks of trichinellosis were registered in Rostov Province in the November and December of 1984 with 16 patients in the Salsk District and 20 patients in Rostov-on-Don. The course of the disease was characterized by 6-20% of severe and 31-45% moderate forms, respectively. The source of the infection was pork that had not been controlled for Trichinella spiralis. Late diagnosis and inadequate treatment in one case led to a fatal outcome. Economic losses accounted for 490,000 rubles (as of 1985). In spite of energetic prophylaxis measures, the situation in the Rostov Province continues to be serious. In 1989-1992, eighteen cases of trichinellosis were registered in the Salsk District again.
In contrast to the other Nordic countries Sweden has long had a favourable position as regards meningococcal disease. In the last 10 year period the annual incidence has been only about one case per 100,000 inhabitants. The treatment once the cause is confirmed is conventional and no different from that in the other Nordic countries but varies somewhat in the event of unknown etiology. Cortisone therapy also seems to be more frequent in treatment of meningitis. Two strategies for antibiotic prophylaxis are used in Sweden.