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273 records – page 1 of 28.

[3',5'-cAMP phosphodiesterase inhibitors in the combined treatment of patients with rheumatoid arthritis]

https://arctichealth.org/en/permalink/ahliterature14188
Source
Lik Sprava. 1998 Aug;(6):34-7
Publication Type
Article
Date
Aug-1998
Author
O I Bakaliuk
M I Shved
M V Hrebenyk
Source
Lik Sprava. 1998 Aug;(6):34-7
Date
Aug-1998
Language
Ukrainian
Publication Type
Article
Keywords
3',5'-Cyclic-Nucleotide Phosphodiesterase - antagonists & inhibitors
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - drug therapy - immunology - metabolism
Combined Modality Therapy
Comparative Study
Drug Evaluation
English Abstract
Glucosephosphate Dehydrogenase - blood - drug effects
Humans
Immunity, Cellular - drug effects
Immunity, Natural - drug effects
Lipid Peroxidation - drug effects
Papaverine - therapeutic use
Phosphodiesterase Inhibitors - therapeutic use
Prospidium - therapeutic use
Abstract
A study was made of clinical effectiveness and mechanism of action of the inhibitor of the specific 3',5'-cAMP phosphodiesterase papaverine in a therapeutic complex of measures designed to treat RA patients involving an immunodepressive preparation free from any cytopenic effect prospidin as a basic mediator. It has been shown that the papaverine antiarthritic action is associated with its positive effects on the unspecific component of the immune-complex inflammation, viz. processes of lipid peroxidation, activity of the antioxidant system of defence as well as on the vascular tone and microcirculation. All this improves tissue metabolism, and in this way enhances efficiency of RA basic therapy.
PubMed ID
9844866 View in PubMed
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[About non-specific prophylaxis of infections typical for organized groups].

https://arctichealth.org/en/permalink/ahliterature117398
Source
Voen Med Zh. 2012 Nov;333(11):51-6
Publication Type
Article
Date
Nov-2012
Author
V V Valevskii
V V Alekseev
G G Mar'in
A A Sobolev
O A Gruzdeva
N N Tsapkova
A V Tutel'ian
G I Poriadina
T A Salmina
A Iu Riazanova
M A Sokolov
D V Sibilev
Source
Voen Med Zh. 2012 Nov;333(11):51-6
Date
Nov-2012
Language
Russian
Publication Type
Article
Keywords
Community-Acquired Infections - epidemiology - immunology - prevention & control
Humans
Immunity, Cellular - drug effects
Immunity, Humoral - drug effects
Military Personnel
Plant Preparations - administration & dosage - therapeutic use
Pyoderma - epidemiology - immunology - prevention & control
Respiratory Tract Infections - epidemiology - immunology - prevention & control
Russia
Seasons
Abstract
Respiratory tract infections and pyodermia are typical for personnel doing military service under conscription. Risk of progression of these infections is connected with activation of carry-over of causative agents among military personnel during replacement and decrease in immunity of conscripts. Usage of medication "Karmolis Kapli" for the purpose of prophylaxis allows to reduce cases of respiratory tract infections among the military personnel. Among the military servicemen who had take "Karmolis Kapli" was noted reduction of community-acquired pneumonia, tonsillitis and pyodermia morbidity. Non-specific protective effect of medication "Karmolis Kapli" is conditioned by increase of the common resistance of the body. For the purpose of prophylaxis it is necessary to use this medication during the personnel formation before the beginning of seasonal morbidity.
PubMed ID
23301292 View in PubMed
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[A comparative analysis of the course of odontogenic phlegmons of the face and neck area in patients from Yakutsk and Moscow].

https://arctichealth.org/en/permalink/ahliterature209864
Source
Stomatologiia (Mosk). 1997;76(4):23-6
Publication Type
Article
Date
1997
Author
S V Filippov
Iu I Chergeshtov
K A Lebedev
Source
Stomatologiia (Mosk). 1997;76(4):23-6
Date
1997
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Cellulitis - immunology - surgery
Face
Female
Focal Infection, Dental - immunology - surgery
Humans
Immunity, Cellular
Male
Middle Aged
Neck
Postoperative Period
Russia
Urban Population
Abstract
A total of 126 patients with odontogenic inflammatory diseases were examined, 54 of these in Moscow and 72 in Yakutsk. The clinical and immunological parameters were assessed on days 2 and 6 after similar operations. In residents of Yakutsk the inflammatory process was associated with a more expressed intoxication and coursed 1.5 to 2 days longer than in Muscovites; moreover, the residents of Yakutsk developed higher leukocytosis and a drop of T-lymphocyte level with the predominance of T-helpers. Hence, odontogenic inflammations take mainly a hyperergic course in Yakutsk and a normergic one in Moscow.
PubMed ID
9381489 View in PubMed
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[Acquired immunodeficiency syndrome, Kaposi's disease and cerebral toxoplasmosis in a young man. Review of the literature apropos of a case]

https://arctichealth.org/en/permalink/ahliterature8813
Source
Ann Dermatol Venereol. 1984;111(1):11-23
Publication Type
Article
Date
1984
Author
M. Janier
A M Perroud
J. Revuz
J. Wechsler
M. Feuilhade
J. Poirier
J P Caron
R. Touraine
Source
Ann Dermatol Venereol. 1984;111(1):11-23
Date
1984
Language
French
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - diagnosis - epidemiology - etiology
Adult
Brain Diseases - etiology
English Abstract
France
Homosexuality
Humans
Immunity, Cellular
Male
Sarcoma, Kaposi - etiology
Skin Neoplasms - etiology
Toxoplasmosis - etiology
United States
Virus Diseases - immunology
Abstract
We report a new case of acquired immune-deficiency syndrome (AIDS) in a 43 year-old white homosexual man, characterized by the association of disseminated cutaneo-mucous Kaposi's sarcoma and cerebral toxoplasmosis. This man had Kaposi's sarcoma for about 10 years but evolution became quickly extensive in July 1981. Chlorambucil was prescribed at that time and was the cause of a pancytopenia. Death occurred in July 1982 due to a cerebral mass identified as toxoplasmosis on a left temporal biopsy. This observation is typical of AIDS, a new syndrome which suddenly developed in the last 2 years in the United States in homosexual men, Haitians and hemophiliacs, and is characterized by disseminated Kaposi's sarcoma and/or opportunistic infections, with a very high mortality rate. Severe toxoplasmosis of CNS has been reported in AIDS and appears to result from defects in cellular immunity which permit recrudescence of latent infection. Cerebral biopsy is necessary for the diagnosis of cerebral toxoplasmosis as seroconversion occurs infrequently in immuno-suppressed hosts. AIDS appeared in Western Europe in 1982. Most of the cases were reported in France, Denmark, Belgium and Great Britain. These cases differ from reported cases in the USA: fewer drug or poppers users, fewer homosexual men, an important number of people having lived or travelled in the Kaposi's endemic area (Mediterranean basin and Central Africa). The immunological profile of patients presenting AIDS in Europe doesn't seem to differ from the american profile: serious cellular immunodeficiency and marked increase in the suppressor/cytotoxic cell population. As in the United States, one may suspect, among several hypotheses, that it is caused by one or several transmissible agents now present in France. The nature of these agents, transmissible by sexual contacts and blood, is not yet known: the role of the CMV is now less probable and most of the studies look for the role of other factors such as the HTLV.
PubMed ID
6375520 View in PubMed
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[Acute and chronic alcoholic intoxication as a cause of modified immunological reactivity in patients with generalized peritonitis]

https://arctichealth.org/en/permalink/ahliterature94540
Source
Vestn Ross Akad Med Nauk. 2009;(6):19-23
Publication Type
Article
Date
2009
Author
Loktin E M
Firsov S A
Pliaskin A E
Shpagina L A
Source
Vestn Ross Akad Med Nauk. 2009;(6):19-23
Date
2009
Language
Russian
Publication Type
Article
Keywords
Acute Disease
Alcoholic Intoxication - complications - epidemiology - immunology
Chronic Disease
Follow-Up Studies
Humans
Immunity, Cellular
Incidence
Male
Middle Aged
Peritonitis - epidemiology - etiology - immunology
Retrospective Studies
Severity of Illness Index
Siberia - epidemiology
T-Lymphocytes - immunology
Abstract
The importance of assessment of immunological reactivity in patients with generalized peritonitis suffering alcoholic intoxication ensues from the possibility to use it for the prediction of abdominal inflammation dynamics and thereby for the optimization of organ-protective therapy in critical situations.
PubMed ID
19645100 View in PubMed
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Acute laryngotracheitis in the rat induced by Sendai virus: the influx of six different types of immunocompetent cells into the laryngeal mucosa differs strongly between the subglottic and the glottic compartment.

https://arctichealth.org/en/permalink/ahliterature31970
Source
Laryngoscope. 2001 Sep;111(9):1645-51
Publication Type
Article
Date
Sep-2001
Author
P. Jecker
A. McWilliam
A. Marsh
P G Holt
W J Mann
R. Pabst
J. Westermann
Author Affiliation
Department of Otolaryngology, Mainz Medical School, Mainz, Germany.
Source
Laryngoscope. 2001 Sep;111(9):1645-51
Date
Sep-2001
Language
English
Publication Type
Article
Keywords
Acute Disease
Animals
B-Lymphocytes - immunology
Dendritic Cells - cytology - immunology
Disease Models, Animal
Gene Expression Regulation, Viral - immunology
Genes, MHC Class II - immunology
Glottis - cytology - immunology
Immunity, Cellular - immunology
Immunity, Mucosal - immunology
Immunocompetence - immunology
Immunohistochemistry
Killer Cells, Natural - immunology
Laryngeal Mucosa - cytology - immunology
Laryngitis - immunology - virology
Leukocyte Count
Macrophages - immunology
Neutrophils - immunology
Rats
Respirovirus
Respirovirus Infections - complications
T-Lymphocytes - immunology
Tracheitis - immunology - virology
Abstract
OBJECTIVES: Acute laryngotracheitis is a disease in which mainly the subglottic area is infected, whereas adjacent parts of the larynx, especially the narrow glottic fold, remain unaffected. The reason for the difference between these two directly adjacent regions is unknown. Therefore, in the present study the influx of dendritic cells, neutrophils, T and B lymphocytes, natural killer cells, and macrophages into the mucosa of different laryngeal compartments was investigated after Sendai virus infection in the rat. The aims were to study both the influx of immunocompetent cells and the adhesion of the pathogen and to correlate them to the different reactions of the laryngeal areas during pseudocroup. METHODS: Acute laryngotracheitis was induced by intranasal application of Sendai virus in brown Norway rats. This virus is exclusively pneumotropic in rodents and belongs to the parainfluenza virus type 1, the main pathogen of acute laryngotracheitis in children. The numbers of dendritic cells, neutrophils, T and B lymphocytes, natural killer cells, and macrophages were determined in the supraglottic, glottic, subglottic, and tracheal mucosa on days 2, 5, 7, and 14 after virus application. Furthermore, the nucleoprotein of the virus and major histocompatibility complex (MHC) Class II expression were detected immunohistologically on the laryngeal epithelium. RESULTS: All cell subsets entered the laryngeal mucosa during inflammation. The highest influx was detected among dendritic cells subglottically. This was accompanied by a strong virus adhesion and MHC Class II expression on the subglottic epithelium. In contrast, only a few immunocompetent cells entered the adjacent glottic mucosa, and on the glottic epithelium staining for virus nucleoprotein and MHC Class II expression was weak. CONCLUSIONS: The inflammatory response of the laryngeal mucosa shows great regional differences in this animal model during experimental viral infection. The response was characterized by a strong subglottic and a weak glottic reaction. A possible reason for this difference might be region-specific viral adhesion on the epithelium of the laryngeal areas, as well as differences in MHC Class II expression. Thus, these data agree with the clinical observation during acute laryngotracheitis and may explain why the subglottic part of the larynx is affected preferentially during pseudocroup. The molecular mechanisms mediating the different reactions await clarification.
PubMed ID
11568621 View in PubMed
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[Adaptive immune response of people living near chemically hazardous object].

https://arctichealth.org/en/permalink/ahliterature127016
Source
Voen Med Zh. 2011 Oct;332(10):15-23
Publication Type
Article
Date
Oct-2011
Author
S V Petlenko
M B Ivanov
Iu B Goverdovskii
E G Bogdanova
A V Golubkov
Source
Voen Med Zh. 2011 Oct;332(10):15-23
Date
Oct-2011
Language
Russian
Publication Type
Article
Keywords
Environmental Exposure - adverse effects
Female
Hazardous Substances - adverse effects
Humans
Immunity, Cellular - drug effects
Male
Russia
Time Factors
Abstract
The article presents data dynamics of adaptive immune responses of people for a long time living in adverse environmental conditions caused by pollution of the environment by industrial toxic waste. It is shown that in the process of adaptation to adverse environmental factors, changes in the immune system are in the phase fluctuations of immunological parameters that are accompanied by changes in the structure of immunodependent pathology. Most sensitive to prolonged exposure to toxic compounds are the cellular mechanisms of immune protection. Violations of the structural and quantitative and functional parameters of the link of the immune system are leading to the formation of immunopathological processes.
PubMed ID
22332391 View in PubMed
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Affects of ionizing radiation on T-cell population lymphocyte: a risk factor of irritable bowel syndrome.

https://arctichealth.org/en/permalink/ahliterature97544
Source
Toxicol Ind Health. 2010 Jul;26(6):323-30
Publication Type
Article
Date
Jul-2010
Author
M R Sheikh Sajjadieh
L V Kuznetsova
V B Bojenko
Author Affiliation
Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev, Ukraine. mohammad_esfahan@yahoo.com
Source
Toxicol Ind Health. 2010 Jul;26(6):323-30
Date
Jul-2010
Language
English
Publication Type
Article
Keywords
Adolescent
Antigens, CD3 - immunology
CD4-CD8 Ratio
CD4-Positive T-Lymphocytes - radiation effects
CD8-Positive T-Lymphocytes - radiation effects
Case-Control Studies
Cesium Radioisotopes - adverse effects
Chernobyl Nuclear Accident
Child
Child, Preschool
Dose-Response Relationship, Radiation
Humans
Immunity, Cellular - radiation effects
Irritable Bowel Syndrome - etiology
Lymphocyte Count
Risk factors
T-Lymphocytes - radiation effects
Abstract
Irritable bowel syndrome is observed mostly in Ukrainian children and may be related to adverse health effects as a result of the Chernobyl disaster. The aim of this study was to determine status of T-cell population lymphocytes in children with clinical symptom of irritable bowel syndrome. The test population consisted of 95 participants: 75 rural patients aged 4 to 18 who lived in a contaminated area exposed to natural environmental radiation with clinical symptom of irritable bowel syndrome (categorized in three groups) and 20 healthy urban participants from Kiev aged 5 to 15 as control group. Internal radiation activity has been measured by gamma-ray spectrometry. Peripheral blood leukocytes were analyzed for T-lymphocytes subset such as T-lymphocytes (CD3(+)), T-helper (CD4(+)) and T-cytotoxic (CD8(+)) and then CD4/CD8 ratio was calculated. Percentage of CD3(+) and CD4(+) in all study groups decreased significantly in comparison to control group (p
PubMed ID
20348276 View in PubMed
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[Age-related characteristics of the immune status in children of the first year of life in the Amur region]

https://arctichealth.org/en/permalink/ahliterature37329
Source
Pediatriia. 1991;(6):109-10
Publication Type
Article
Date
1991

273 records – page 1 of 28.