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Alanine aminotransferase, gamma-glutamyltransferase, antibodies to hepatitis B core antigen and antibodies to hepatitis C virus in blood donor screening. A prospective study in Finland.

https://arctichealth.org/en/permalink/ahliterature227650
Source
Vox Sang. 1991;60(4):219-24
Publication Type
Article
Date
1991
Author
F. Ebeling
Author Affiliation
Finnish Red Cross Blood Transfusion Service, Helsinki.
Source
Vox Sang. 1991;60(4):219-24
Date
1991
Language
English
Publication Type
Article
Keywords
Alanine Transaminase - analysis
Blood Donors
Blood Transfusion - standards
Finland
Hepacivirus - immunology
Hepatitis Antibodies - analysis
Hepatitis B Antibodies - analysis
Hepatitis B Core Antigens - immunology
Hepatitis C - transmission
Humans
Prospective Studies
gamma-Glutamyltransferase - analysis
Abstract
Alanine aminotransferase (ALT), gamma-glutamyl-transferase and hepatitis B core antibodies were evaluated as donor markers in a prospective study of 685 open-heart surgery patients. Of these three surrogate markers, only an ALT level greater than or equal to 2 SD above the log mean had a significant association with recipient non-A, non-B hepatitis (NANBH, p = 0.02). Antibodies to the hepatitis C virus (anti-HCV) were detected by an enzyme immunoassay in 7 of the 136 units transfused to the 11 NANBH patients and 29 of 3,650 not associated with hepatitis (p less than 0.001). Calculated from this subgroup of donors, the anti-HCV test would have a 15.6% positive predictive value with 0.92% donor loss and thus is superior as a primary screening marker to all the three surrogate tests. The predictive value could be substantially increased by subsequent ALT testing or by the use of a recombinant immunoblot anti-HCV assay.
Notes
Comment In: Vox Sang. 1992;62(4):246-71642006
PubMed ID
1681620 View in PubMed
Less detail

Canada's HIV blood inquiry turns poisonous.

https://arctichealth.org/en/permalink/ahliterature210319
Source
Nature. 1996 Dec 19-26;384(6610):602
Publication Type
Article
Author
D. Spurgeon
Source
Nature. 1996 Dec 19-26;384(6610):602
Language
English
Publication Type
Article
Keywords
Blood - virology
Blood Banks - legislation & jurisprudence - organization & administration
Canada
HIV
HIV Infections - transmission
Hepatitis C - transmission
Humans
Notes
Comment In: Nature. 1997 Feb 13;385(6617):5749024649
PubMed ID
8967941 View in PubMed
Less detail

Canadians seek justice probe in sale of prison blood.

https://arctichealth.org/en/permalink/ahliterature194610
Source
Newsline People AIDS Coalit N Y. 1999 Apr-May;:32
Publication Type
Article

Confirmation of nosocomial transmission of hepatitis C virus by phylogenetic analysis of the NS5-B region.

https://arctichealth.org/en/permalink/ahliterature56725
Source
J Clin Microbiol. 1998 Oct;36(10):3066-9
Publication Type
Article
Date
Oct-1998
Author
H. Norder
A. Bergström
I. Uhnoo
J. Aldén
L. Weiss
J. Czajkowski
L. Magnius
Author Affiliation
Swedish Institute for Infectious Disease Control, Stockholm, Central Hospital, Karlstad, Sweden. helene.norder@smi.ki.se
Source
J Clin Microbiol. 1998 Oct;36(10):3066-9
Date
Oct-1998
Language
English
Publication Type
Article
Keywords
Cross Infection - transmission - virology
DNA Primers
Female
Hepacivirus - genetics - isolation & purification
Hepatitis C - transmission
Humans
Male
Molecular Sequence Data
Phylogeny
Renal Dialysis - adverse effects
Research Support, Non-U.S. Gov't
Software
Sweden
Viral Nonstructural Proteins - genetics
Abstract
Four hepatitis C virus transmission chains at three dialysis units were disclosed by limited sequencing; three of these were disclosed by analysis of the NS5-B region of the genome. Dialysis on the same shift as that during which infected patients were dialyzed was the common factor for seven patients in two chains. Two nurses exposed to needle sticks and their sources of infection constituted two other chains. The strains of three chains belonged to subtype 1a and formed clusters with an intrachain variability of 0 to 6 nucleotides compared to 8 to 37 nucleotides for unrelated strains within this subtype. The clusters were supported by bootstrap values ranging from 89 to 100%.
PubMed ID
9738071 View in PubMed
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Criminal law and HIV transmission/exposure: more new cases.

https://arctichealth.org/en/permalink/ahliterature181839
Source
Can HIV AIDS Policy Law Rev. 2002 Dec;7(2-3):74-6
Publication Type
Article
Date
Dec-2002

Criminal law and HIV transmission or exposure.

https://arctichealth.org/en/permalink/ahliterature136114
Source
HIV AIDS Policy Law Rev. 2010 Oct;15(1):23-6
Publication Type
Article
Date
Oct-2010

[Exposure to blood among hospital physicians]

https://arctichealth.org/en/permalink/ahliterature8111
Source
Tidsskr Nor Laegeforen. 1993 Jan 10;113(1):24-6
Publication Type
Article
Date
Jan-10-1993
Author
S. Aarseth
S. Vatn
H P Aarseth
Author Affiliation
Bedriftshelsetjenesten, Sentralsykehuset, Akershus, Nordbyhagen.
Source
Tidsskr Nor Laegeforen. 1993 Jan 10;113(1):24-6
Date
Jan-10-1993
Language
Norwegian
Publication Type
Article
Keywords
Adult
Blood - microbiology
English Abstract
HIV Seropositivity - transmission
Hepatitis B - transmission
Hepatitis C - transmission
Humans
Medical Staff, Hospital
Middle Aged
Norway
Occupational Diseases - etiology - microbiology
Occupational Exposure
Physicians
Questionnaires
Risk factors
Abstract
We used a questionnaire to study the working situation of physicians in two large Norwegian hospitals. During the last six months 40% of the doctors reported one or more episodes of exposure to blood when transfer of infectious agents such as hepatitis B-virus or HIV would have been possible. The fact that so many doctors had been exposed to blood conflicts with the low number reported to the hospital department of the occupational health service. Surprisingly, 40% of the physicians who reported exposure were physicians not taking part in surgical procedures. All hospitals should establish follow-up procedures for employees exposed to blood or other possible infectious agents, and physicians should be urged to follow these routines.
PubMed ID
8424245 View in PubMed
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Factors associated with difficulty accessing crack cocaine pipes in a Canadian setting.

https://arctichealth.org/en/permalink/ahliterature125660
Source
Drug Alcohol Rev. 2012 Nov;31(7):890-6
Publication Type
Article
Date
Nov-2012
Author
Lianping Ti
Jane Buxton
Evan Wood
Kate Shannon
Ruth Zhang
Julio Montaner
Thomas Kerr
Author Affiliation
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Source
Drug Alcohol Rev. 2012 Nov;31(7):890-6
Date
Nov-2012
Language
English
Publication Type
Article
Keywords
Adult
British Columbia - epidemiology
Cocaine-Related Disorders - epidemiology
Cohort Studies
Crack Cocaine - administration & dosage
Female
Follow-Up Studies
Harm Reduction
Hepatitis C - transmission
Humans
Male
Middle Aged
Multivariate Analysis
Prospective Studies
Risk-Taking
Abstract
Crack cocaine pipe sharing is associated with various health-related harms, including hepatitis C transmission. Although difficulty accessing crack pipes has been found to predict pipe sharing, little is known about the factors that limit pipe access in settings where pipes are provided at no cost, albeit in limited capacity. Therefore, we investigated crack pipe access among people who use drugs in Vancouver, Canada.
Data were collected through two Canadian prospective cohort studies. Generalised estimating equations with logit link for binary outcomes were used to identify factors associated with difficulty accessing crack pipes.
Among 914 participants who reported using crack cocaine, 33% reported difficulty accessing crack pipes. In multivariate analyses, factors independently associated with difficulty accessing crack pipes included: sex work involvement [adjusted odds ratio (AOR) = 1.57; 95% confidence interval (CI): 1.03-2.39], having shared a crack pipe (AOR = 1.69; 95% CI: 1.32-2.16), police presence where one buys/uses drugs (AOR = 1.47; 95% CI: 1.10-1.95), difficulty accessing services (AOR = 1.74; 95% CI: 1.31-2.32) and health problems associated with crack use (AOR = 1.37; 95% CI: 1.04-1.79). Reasons given for difficulty accessing pipes included sources being closed (48.2%) and no one around selling pipes (18.1%).
A substantial proportion of people who smoke crack cocaine report difficulty accessing crack pipes in a setting where pipes are available at no cost but in limited quantity. These findings indicate the need for enhanced efforts to distribute crack pipes and address barriers to pipe access.
Notes
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PubMed ID
22462808 View in PubMed
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Final charges against former director of Canadian Red Cross withdrawn.

https://arctichealth.org/en/permalink/ahliterature155458
Source
HIV AIDS Policy Law Rev. 2008 Jul;13(1):54-5
Publication Type
Article
Date
Jul-2008

35 records – page 1 of 4.