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Hepatitis B immune globulin in prevention of hepatitis B among hospital staff members.

https://arctichealth.org/en/permalink/ahliterature57070
Source
J Infect Dis. 1977 Mar;135(3):473-7
Publication Type
Article
Date
Mar-1977
Author
S. Iwarson
J. Ahlmén
E. Eriksson
S. Hermodsson
H. Kjellman
C. Ljunggren
D. Selander
Source
J Infect Dis. 1977 Mar;135(3):473-7
Date
Mar-1977
Language
English
Publication Type
Article
Keywords
Adult
Antibodies, Viral - administration & dosage - biosynthesis
Clinical Trials
Female
Hepatitis B - prevention & control
Hepatitis B Surface Antigens - isolation & purification
Humans
Immunoglobulins - administration & dosage
Male
Personnel, Hospital
Sweden
Abstract
In a double-blind trial of hospital staff members at risk of contracting hepatitis B, 110 subjects received hepatitis B immune globulin or immune serum globulin prophylactically. An additional 125 individuals working in the same locations were unwilling to participate in the trial and received no prophylaxis. During the study period of 28 months, 13 cases of clinical hepatitis B occurred in the untreated group, whereas only three cases occurred among the subjects who received prophylaxis.
PubMed ID
321704 View in PubMed
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