This study determined the prevalence and factors associated with hepatitis B virus (HBV) infection among men who have sex with men.
At the baseline visit of an HIV study among men who have sex with men, we asked about HBV vaccination status and tested for HBV markers.
Of 625 subjects, 48% had received at least 1 dose of HBV vaccine. Of 328 unvaccinated men, 41% had 1 or more HBV markers. HBV prevalence increased markedly with age and was associated with many sexual and drug-related behaviors. In a multivariate model, 7 variables were independently associated with HBV infection: ulcerative sexually transmitted diseases (odds ratio [OR] = 10.1; 95% confidence interval [CI] = 2.6, 54); injection drug use (OR = 5.2; 95% CI = 1.2, 26); gonorrhea or chlamydia (OR = 4.0; 95% CI = 1.9, 8.9); sexual partner with HIV/AIDS (OR = 3.6; 95% CI = 1.8, 7.1); 50 or more casual partners (OR = 3.4; 95% CI = 1.6, 7.1); received money for sex (OR = 3.0; 95% CI = 1.2, 7.8); and 20 or more regular partners (OR = 2.5; 95% CI = 1.1, 6.1).
In Montreal, men who have sex with men are at risk for HBV infection, but a substantial proportion remain unvaccinated; new strategies are required to improve coverage. Men who have sex with men and who have a sexually transmitted infection, especially a genito-ulcerative infection, appear to be at particularly high risk for HBV infection.
Cites: Can J Public Health. 1994 Sep-Oct;85(5):338-417804940
Cites: Sex Transm Dis. 1999 Jul;26(6):317-2410417018
The paper presents clinicoepidemiological characteristics of VHB associated forms in case of parenteral entry of the infection. This predetermines systemic dissemination of the virus. The preventive measures are discussed.