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[Adaptive immune response of people living near chemically hazardous object].

https://arctichealth.org/en/permalink/ahliterature127016
Source
Voen Med Zh. 2011 Oct;332(10):15-23
Publication Type
Article
Date
Oct-2011
Author
S V Petlenko
M B Ivanov
Iu B Goverdovskii
E G Bogdanova
A V Golubkov
Source
Voen Med Zh. 2011 Oct;332(10):15-23
Date
Oct-2011
Language
Russian
Publication Type
Article
Keywords
Environmental Exposure - adverse effects
Female
Hazardous Substances - adverse effects
Humans
Immunity, Cellular - drug effects
Male
Russia
Time Factors
Abstract
The article presents data dynamics of adaptive immune responses of people for a long time living in adverse environmental conditions caused by pollution of the environment by industrial toxic waste. It is shown that in the process of adaptation to adverse environmental factors, changes in the immune system are in the phase fluctuations of immunological parameters that are accompanied by changes in the structure of immunodependent pathology. Most sensitive to prolonged exposure to toxic compounds are the cellular mechanisms of immune protection. Violations of the structural and quantitative and functional parameters of the link of the immune system are leading to the formation of immunopathological processes.
PubMed ID
22332391 View in PubMed
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[Cytogenetic examination of the workers of higher chemical hazard enterprises and the population of the nearby territories].

https://arctichealth.org/en/permalink/ahliterature128610
Source
Gig Sanit. 2011 Sep-Oct;(5):42-4
Publication Type
Article
Author
T V Kharchenko
L G Arzhavkina
M B Ivanov
A V Iazenok
Iu B Goverdovskii
A S Kriuchkova
D A Siniachkin
A E Sosiukin
Source
Gig Sanit. 2011 Sep-Oct;(5):42-4
Language
Russian
Publication Type
Article
Keywords
Adult
Case-Control Studies
Chemical Industry
Chromosome Aberrations - chemically induced - statistics & numerical data
Cytogenetic Analysis
Hazardous Substances - toxicity
Humans
Lymphocytes - drug effects - ultrastructure
Male
Middle Aged
Occupational Exposure - adverse effects
Russia
Workplace - standards
Young Adult
Abstract
Cytogenetical examination was made in 49 workers of higher chemical hazard enterprises and 26 dwellers from industrial communities, who were engaged in enterprise security. Analysis of chromosome aberrations (CA) in the examined groups revealed a 1.8-fold increase in total CA rates in the industrial community dwellers securing the enterprise as compared to the controls mainly due to the rise in the rate of single fragments. At the same time in the enterprise workers, the total level of CA was 2.36- and 4.1-fold greater than that in the population of industrial communities and in the controls, respectively; and it was also characterized by a broad spectrum of CA with the increased number of both chromatid and chromosomal exchange aberrations.
PubMed ID
22185001 View in PubMed
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