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Acute poisonings in Iceland: a prospective nationwide study.

https://arctichealth.org/en/permalink/ahliterature86765
Source
Clin Toxicol (Phila). 2008 Feb;46(2):126-32
Publication Type
Article
Date
Feb-2008
Author
Kristinsson Jakob
Palsson Runolfur
Gudjonsdottir Gudborg A
Blondal Margret
Gudmundsson Sigurdur
Snook Curtis P
Author Affiliation
Institute of Pharmacy, Pharmacology and Toxicology, University of Iceland, Reykjavik, Iceland.
Source
Clin Toxicol (Phila). 2008 Feb;46(2):126-32
Date
Feb-2008
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Age Factors
Alcoholic Beverages - poisoning
Child
Child, Preschool
Circadian Rhythm
Counseling - methods
Data Collection - methods - statistics & numerical data
Emergency Service, Hospital - statistics & numerical data
Female
Hazardous Substances - classification - poisoning
Humans
Iceland - epidemiology
Incidence
Male
Middle Aged
Patient Admission - statistics & numerical data
Poison Control Centers - utilization
Poisoning - epidemiology - prevention & control
Prospective Studies
Rural Health Services - statistics & numerical data
Sex Factors
Suicide, Attempted - statistics & numerical data
Abstract
INTRODUCTION: Poisoning is a common cause of emergency visits and hospital admission in Western countries. The purpose of this study was to assess the incidence and type of toxic exposures presenting to emergency medical facilities in Iceland. MATERIALS AND METHODS: The study was prospective and included all patients with confirmed or suspected poisoning presenting to hospitals and rural medical centers providing emergency services in Iceland during the twelve-month period from April 2001 until March 2002. RESULTS: A total of 1,121 toxic exposures were documented representing an incidence of 3.91 cases per 1,000 inhabitants per year. The female to male ratio was 1.23. The majority of exposures (56.7%) occurred in the patient's home, 60% were deliberate, 72% had drugs and/or alcohol as their main cause, and 11% involved illicit drugs. Exposures to chemicals other than drugs were usually unintentional. CONCLUSION: Toxic exposures requiring emergency medical care are common in Iceland. Self-poisonings by ingestion of prescription drugs and/or alcohol accounted for the majority of cases.
PubMed ID
18259960 View in PubMed
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[Administration of essential phospholipids in persons exposed to chemical industrial pollutants].

https://arctichealth.org/en/permalink/ahliterature180414
Source
Ter Arkh. 2004;76(2):63-6
Publication Type
Article
Date
2004
Author
L A Shpagina
S V Bobrov
Source
Ter Arkh. 2004;76(2):63-6
Date
2004
Language
Russian
Publication Type
Article
Keywords
Antioxidants - administration & dosage - therapeutic use
Hazardous Substances - poisoning
Humans
Liver Function Tests
Occupational Diseases - drug therapy - etiology
Occupational Exposure - adverse effects
Phosphatidylcholines - administration & dosage - therapeutic use
Poisoning - drug therapy - etiology
Russia
Treatment Outcome
Abstract
To examine efficacy of the drug essliver-forte in patients with chronic intoxication by a complex of such toxicants as soluble and unsoluble compounds of uranium, lead and mercury.
The examination of bilirubin, synthesis of proteins and enzyme production by the liver, activity of free radical lipid oxidation and antioxidant defence was conducted in 42 persons (mean age 66.4 +/- 4.2 years) occupationally exposed to chemicals (compounds of uranium, lead and mercury) for 12.6 +/- 1.8 years. The patients were divided into two equal groups: patients of group 1 received standard therapy with enterosorbents, cerebral angioprotectors and alpha-tocopherol; patients of group 2 instead of alpha-tocopherol were given essliver-forte (2 capsules twice a day).
Patients of group 2 had significantly less frequent complaints for fatigue, anxiety, dyspnea, sleep disorders; improvement was observed in peripheral blood counts, in concentrations of alpha 2- and gamma-globulins, sulfhydril and catalase activity of erythrocytes; transaminase activity and intensity of saponin hemolysis went down.
Essliver-forte is effective in persons occupationally exposed to chemicals.
PubMed ID
15106419 View in PubMed
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An indicator for effects of organic toxicants on lotic invertebrate communities: Independence of confounding environmental factors over an extensive river continuum.

https://arctichealth.org/en/permalink/ahliterature93021
Source
Environ Pollut. 2008 Dec;156(3):980-7
Publication Type
Article
Date
Dec-2008
Author
Beketov Mikhail A
Liess Matthias
Author Affiliation
UFZ-Helmholtz Centre for Environmental Research, Department of System Ecotoxicology, Permoserstrasse 15, D-04318 Leipzig, Germany. mikhail.beketov@ufz.de
Source
Environ Pollut. 2008 Dec;156(3):980-7
Date
Dec-2008
Language
English
Publication Type
Article
Keywords
Animals
Biodiversity
Ecology - methods
Ecosystem
Environmental Monitoring - methods
Food chain
Hazardous Substances - toxicity
Invertebrates - drug effects - physiology
Organic Chemicals - toxicity
Rivers
Siberia
Species Specificity
Water Pollutants, Chemical - toxicity
Abstract
Distinguishing between effects of natural and anthropogenic environmental factors on ecosystems is a fundamental problem in environmental science. In river systems the longitudinal gradient of environmental factors is one of the most relevant sources of dissimilarity between communities that could be confounded with anthropogenic disturbances. To test the hypothesis that in macroinvertebrate communities the distribution of species' sensitivity to organic toxicants is independent of natural longitudinal factors, but depends on contamination with organic toxicants, we analysed the relationship between community sensitivity SPEAR(organic) (average community sensitivity to organic toxicants) and natural and anthropogenic environmental factors in a large-scale river system, from alpine streams to a lowland river. The results show that SPEAR(organic) is largely independent of natural longitudinal factors, but strongly dependent on contamination with organic toxicants (petrochemicals and synthetic surfactants). Usage of SPEAR(organic) as a stressor-specific longitude-independent measure will facilitate detection of community disturbance by organic toxicants.
PubMed ID
18547697 View in PubMed
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[Approaches to evaluation of translocated pollution].

https://arctichealth.org/en/permalink/ahliterature192070
Source
Med Tr Prom Ekol. 2001;(11):23-8
Publication Type
Article
Date
2001
Author
O V Mitrokhin
Source
Med Tr Prom Ekol. 2001;(11):23-8
Date
2001
Language
Russian
Publication Type
Article
Keywords
Asthma - epidemiology
Catchment Area (Health)
Environmental Pollution - adverse effects - statistics & numerical data
Hazardous Substances - adverse effects
Humans
Risk factors
Russia - epidemiology
Abstract
The authors suggested criteria of translocated pollution: scale, intensity, jeopardy, with consideration of dissemination mechanism--aerodynamic, water migration, terminal. The article covers classification of translocated pollution. Using methodology of risk evaluation, the authors assessed additional morbidity cases due to translocated pollution.
PubMed ID
11768950 View in PubMed
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Beyond the workplace: an exploratory study of the impact of neurotoxic workplace exposure on marital relations.

https://arctichealth.org/en/permalink/ahliterature199709
Source
Am J Ind Med. 2000 Mar;37(3):316-23
Publication Type
Article
Date
Mar-2000
Author
D. Julien
D. Mergler
M. Baldwin
M P Sassine
N. Cormier
E. Chartrand
S. Bélanger
Author Affiliation
Department of Psychology, University of Quebec at Montreal, Canada.
Source
Am J Ind Med. 2000 Mar;37(3):316-23
Date
Mar-2000
Language
English
Publication Type
Article
Keywords
Animals
Canada
Cohort Studies
Female
Hazardous Substances - adverse effects
Humans
Male
Marriage - psychology
Mental health
Neurotoxicity Syndromes - complications - etiology
Occupational Exposure
Questionnaires
Rabbits
Abstract
The impact on family life and social relations that may result from symptoms associated with exposure to neurotoxic substances has never been addressed. This exploratory study assessed the associations between exposure to neurotoxic agents in the workplace, mental health, and marital difficulties.
Fifty-five (55) male workers and their spouses completed standardized measures of mental health and marital difficulties. Workers' exposure to neurotoxic substances was evaluated by questionnaire and interview, using a semiquantitative classification system.
A positive relation was observed between exposure level and measures of workers' psychological symptoms and marital stress; no relation was observed between workers' exposure level and wives' psychological symptoms. More severe exposure to neurotoxic substances was associated with wives' reports of more severe marital conflicts, and this association was mediated by husbands' psychological symptoms. As compared to low exposure husbands, high exposure husbands reported higher degrees of stress surrounding marital discussions, more consistent incidence of minor physical assaults by wives, and stronger associations between their levels of stress, the verbal aggressions of wives, and the number of marital conflicts.
The results of this study confirm that neurotoxic exposure is a risk factor for mental health and suggest how this may influence marital relations. Because of the importance of these findings for the well-being of workers and their families, these associations should be further studied.
PubMed ID
10642423 View in PubMed
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Biologically motivated quantitative models and the mixture toxicity problem.

https://arctichealth.org/en/permalink/ahliterature193644
Source
Toxicol Sci. 2001 Sep;63(1):1-2
Publication Type
Article
Date
Sep-2001
Author
R B Conolly
Author Affiliation
CIIT Centers for Health Research, Center for Computational Biology and Extrapolation Modeling, 6 Davis Drive, Research Triangle Park, NC 27709, USA. rconnolly@ciit.org
Source
Toxicol Sci. 2001 Sep;63(1):1-2
Date
Sep-2001
Language
English
Publication Type
Article
Keywords
Animals
Dose-Response Relationship, Drug
Drug Synergism
Hazardous Substances - pharmacokinetics - toxicity
Humans
Models, Biological
Risk assessment
Species Specificity
Toxicity Tests
Abstract
The article highlighted in this issue is "A PBPK Modeling-Based Approach to Account for Interactions in the Health Risk Assessment of Chemical Mixtures" by Sami Haddad, Martin Béliveau, Robert Tardif, and Kannan Krishnan (pp. 125-131).
Notes
Comment On: Toxicol Sci. 2001 Sep;63(1):125-3111509752
PubMed ID
11509736 View in PubMed
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[Biologic prophylaxis of intoxications with inorganic compounds].

https://arctichealth.org/en/permalink/ahliterature177176
Source
Med Tr Prom Ekol. 2004;(9):19-23
Publication Type
Article
Date
2004
Author
B A Katsnel'son
T D Degtiareva
L I Privalova
O L Malykh
V B Gurvich
S V Kuz'min
O Iu Beresneva
Source
Med Tr Prom Ekol. 2004;(9):19-23
Date
2004
Language
Russian
Publication Type
Article
Keywords
Hazardous Substances - toxicity
Humans
Inorganic Chemicals - toxicity
Occupational Diseases - chemically induced - prevention & control
Occupational Exposure - adverse effects
Preventive Health Services - organization & administration
Russia
Abstract
The authors summarize theoretical principles of increasing human resistence to toxic effects of inorganic compounds polluting occupational environment and habitat, exemplify practical use of this prophylactic trend.
PubMed ID
15568564 View in PubMed
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76 records – page 1 of 8.