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[Acute respiratory tract infections and mannose-binding lectin insufficiency in small children]

https://arctichealth.org/en/permalink/ahliterature31200
Source
Ugeskr Laeger. 2002 Nov 25;164(48):5635-40
Publication Type
Article
Date
Nov-25-2002
Author
Anders Koch
Mads Melbye
Per Sørensen
Preben Homøe
Hans O Madsen
Kåre Mølbak
Christoffer Holst Hansen
Lasse Høgh Andersen
Gitte Weinkauff Hahn
Peter Garred
Author Affiliation
Afdeling for epidemiologisk forskning, Statens Serum Institut, Artillerivej 5, DK-2300 København S. ako@ssi.dk
Source
Ugeskr Laeger. 2002 Nov 25;164(48):5635-40
Date
Nov-25-2002
Language
Danish
Publication Type
Article
Keywords
Acute Disease
Alleles
Child, Preschool
Cohort Studies
Denmark - ethnology
English Abstract
Genotype
Greenland - ethnology
Humans
Infant
Infant, Newborn
Mannose-Binding Lectin - deficiency - genetics - immunology
Prospective Studies
Research Support, Non-U.S. Gov't
Respiratory Tract Infections - blood - genetics
Risk factors
Abstract
INTRODUCTION: According to hospital-based studies, increased susceptibility to certain infections is associated with genotypes that cause low serum levels of the protein mannose-binding lectin (MBL). However, the contribution of MBL insufficiency to the incidence of common childhood infections on a population basis is unknown. To investigate the effect of MBL insufficiency on the risk of acute respiratory infections (ARI) in unselected children, we performed a prospective population-based study of ARI in young children in Sisimiut, Greenland. MATERIAL AND METHODS: An open cohort of children aged 0-2 years was formed in 1996, and followed up with weekly morbidity surveillance visits for a two-year period. Episodes of ARI were diagnosed on medical history and clinical examinations. MBL genotypes were determined from blood samples according to the presence of structural alleles and promoter alleles. RESULTS: Altogether 294 children participated and 44 refused. Blood samples were taken from 252 participants. A 2.1-fold (95% confidence interval 1.4-3.1) increased risk of ARI was found in MBL-insufficient children compared with MBL-sufficient children (p
PubMed ID
12523009 View in PubMed
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Allergen sensitization and allergen exposure in Greenlander Inuit residing in Denmark and Greenland.

https://arctichealth.org/en/permalink/ahliterature188475
Source
Respir Med. 2002 Sep;96(9):736-44
Publication Type
Article
Date
Sep-2002
Author
C. Porsbjerg
M L Linstow
S C Nepper-christensen
A. Rasmussen
J. Korsgaard
H. Nolte
V. Backer
Author Affiliation
Department of Internal Medicine, Bispebjerg University Hospital, Copenhagen, Denmark. porsbjerg@dadlnet.dk
Source
Respir Med. 2002 Sep;96(9):736-44
Date
Sep-2002
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Allergens - immunology
Cross-Sectional Studies
Denmark
Dust
Environmental Exposure - adverse effects - statistics & numerical data
Female
Greenland - ethnology
Humans
Hypersensitivity - ethnology - immunology
Inuits
Logistic Models
Male
Middle Aged
Pollen
Prevalence
Residence Characteristics
Skin Tests - methods
Statistics, nonparametric
Abstract
The aim of this study was to estimate the prevalence of allergic sensitization and possible risk factors in a genetically homogenous Inuit population living under widely differing climatic and cultural conditions. A written questionnaire and skin prick test for 10 aeroallergens were obtained from 1119 adult Greenlanders residing in Denmark, Nuuk (main city in Southern Greenland) and Uummannaq (rural settlement in Northern Greenland). Allergen exposure was assessed by pollen counts, questions on pet keeping and counts of house dust mites in dust samples. The overall prevalence of at least one positive skin prick test was 22.8% in Denmark, 10.6% in Nuuk, and 6.4% in Uummannaq. In Denmark, the total birch pollen counts were 40-1000 times higher compared to Nuuk, whereas the grass pollen count was 13-30 times higher in Denmark compared to Nuuk. Dogs were held indoor with a similar frequency in Denmark and Nuuk, but much less frequently in Uummannaq. In Denmark, house dust mites were found in 72% of house holds (>10/0.1 g dust). Less than 15% of households in Greenland had measurable levels of house dust mites. The prevalence of sensitization to aeroallergens in Inuit Greenlanders differed significantly between Denmark, Nuuk and Uummannaq. These findings correlated with the observed differences in population allergen exposure in the three regions. Furthermore, differences in lifestyle factors such as educational level, stress and ethnic self-identification seemed to be associated with the risk of allergic sensitization in Greenland.
PubMed ID
12243321 View in PubMed
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Anatomical risk factors in primary angle-closure glaucoma. A ten year follow up survey based on limbal and axial anterior chamber depths in a high risk population.

https://arctichealth.org/en/permalink/ahliterature5400
Source
Int Ophthalmol. 1992 Sep;16(4-5):265-72
Publication Type
Article
Date
Sep-1992
Author
P H Alsbirk
Author Affiliation
Eye Department, Central Hospital, Hillerød, Denmark.
Source
Int Ophthalmol. 1992 Sep;16(4-5):265-72
Date
Sep-1992
Language
English
Publication Type
Article
Keywords
Acute Disease
Adult
Aged
Aged, 80 and over
Anterior Chamber - pathology
Female
Follow-Up Studies
Glaucoma, Angle-Closure - ethnology - pathology
Gonioscopy
Greenland - ethnology
Humans
Inuits
Longitudinal Studies
Male
Middle Aged
Prevalence
Research Support, Non-U.S. Gov't
Risk factors
Abstract
A population of 539 persons was examined in 1979, using LCD and ACD estimations acc. to van Herick et al. and by Haag Streit pachymetry, respectively. ACD had been measured already in 1969, due to a remarkable occurrence of primary angle-closure glaucoma (PACG) in the survey population of Greenland Eskimos (District of Uummannaq). The present follow up study in 1989 aimed at persons presently above age 40, who had shown either an LCD value graded as 0 (contact) or 1 (
PubMed ID
1428555 View in PubMed
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An efficient case finding strategy to diagnose osteoporosis in a developing society with low treatment frequency.

https://arctichealth.org/en/permalink/ahliterature272027
Source
J Endocrinol Invest. 2015 Aug;38(8):841-7
Publication Type
Article
Date
Aug-2015
Author
Vibeke Neergaard Sørensen
Piotr Wojtek
Dorthe S Pedersen
Stig Andersen
Source
J Endocrinol Invest. 2015 Aug;38(8):841-7
Date
Aug-2015
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
European Continental Ancestry Group - ethnology
Female
Greenland - ethnology
Humans
Inuits - ethnology
Male
Middle Aged
Osteoporosis - ethnology - radiography - therapy
Radiography, Thoracic - methods
Spinal Fractures - ethnology - radiography - therapy
Abstract
Osteoporosis is a debilitating condition with rising frequency of fragility fractures with advancing age. Life expectancy increases in developing societies with the emergence of osteoporosis. There is a need for a simple protocol to diagnose fractures that merit treatment for osteoporosis.
Evaluation of all consecutive lateral chest radiographs performed at the National Hospital in the capital city in Greenland over a 3-month period for vertebral body heights at the anterior, middle and posterior regions. Use of anti-osteoporotic drug was evaluated from records of dispensed drugs from Greenland National Pharmacy.
1869 vertebrae were evaluated on radiographs from 203 subjects. On average 9.2 vertebrae (range 5-13) qualified for evaluation in each individual. Median (range) age was 55 (30-82) years. Any vertebral deformity above 25 (20) % was seen in 28.6 (50.2) %. More than one fracture was seen in 10.3 (27.1) %. Fractures occurred in 18.5 (36.9) % of patients from the General Medicine Clinic and in 33.3 (56.5) % of inpatients (p = 0.029). The occurrence of vertebral fractures increased with age (p
PubMed ID
26122488 View in PubMed
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Anterior chamber depth, genes and environment. A population study among long-term Greenland Eskimo immigrants in Copenhagen.

https://arctichealth.org/en/permalink/ahliterature5442
Source
Acta Ophthalmol (Copenh). 1982 Apr;60(2):223-4
Publication Type
Article
Date
Apr-1982
Author
P H Alsbirk
Source
Acta Ophthalmol (Copenh). 1982 Apr;60(2):223-4
Date
Apr-1982
Language
English
Publication Type
Article
Keywords
Adult
Anterior Chamber - anatomy & histology
Anthropometry
Denmark
Glaucoma - epidemiology
Gonioscopy
Greenland - ethnology
Humans
Inuits
Male
Refraction, Ocular
Research Support, Non-U.S. Gov't
Visual acuity
Abstract
Previous population studies have demonstrated a shallow anterior chamber as an inherited characteristic of Eskimos, explaining their high prevalence of primary angle-closure glaucoma. In order to evaluate the stability of the anterior chamber depth (ACD) distribution and its inherent morbidity risk in a different environment, immigrant Greenland Eskimo women in Copenhagen, aged 40 years or more were sampled. Those who had been at least 25 years in Denmark were examined (N = 64), using Haag Streit pachymetry, limbal chamber depth (LCD) estimation and gonioscopy. The ACD level of the immigrants was significantly higher than that of their background population, in ethnically 'mixed' as well as 'pure' subgroups, and correspondingly the LCD grading was higher among the immigrants. Primary angle-closure glaucoma was found in 3%. The refraction showed no significant trend towards myopia compared with native Greenland Eskimos. Environmental factors influencing ACD, e.g. through the rate of biological ageing, seem to exist, but their nature is unknown.
PubMed ID
7136533 View in PubMed
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Antibiotic treatment of venereal disease and Reiter's syndrome in a Greenland population.

https://arctichealth.org/en/permalink/ahliterature3756
Source
Arthritis Rheum. 1992 Feb;35(2):190-4
Publication Type
Article
Date
Feb-1992
Author
T. Bardin
C. Enel
F. Cornelis
C. Salski
C. Jorgensen
R. Ward
G M Lathrop
Author Affiliation
Clinique de Rhumatologie, Hôpital Lariboisière, France.
Source
Arthritis Rheum. 1992 Feb;35(2):190-4
Date
Feb-1992
Language
English
Publication Type
Article
Keywords
Adult
Arthritis - epidemiology - prevention & control
Comparative Study
Erythromycin - therapeutic use
Female
Greenland - ethnology
Humans
Incidence
Inuits
Male
Penicillins - therapeutic use
Recurrence
Reiter Disease - drug therapy
Research Support, Non-U.S. Gov't
Retrospective Studies
Sexually Transmitted Diseases - drug therapy
Tetracycline - therapeutic use
Urethritis - drug therapy
Uterine Cervicitis - drug therapy
Abstract
OBJECTIVE. To assess the effects of antibiotic treatment of urethritis or cervicitis on the incidence of recurrences of articular symptoms in Reiter's syndrome patients. METHODS. Retrospective evaluation of the medical charts of 109 patients living in Greenland. RESULTS. Thirty-seven percent of the episodes of genitourinary tract inflammation that were not treated or were treated with penicillin were followed by arthritis, compared with 10% of those treated with tetracycline or erythromycin. CONCLUSION. Antibiotics active against Chlamydia trachomatis reduced the risk of postvenereal arthritis in the population studied.
PubMed ID
1734908 View in PubMed
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Atherosclerosis in native Greenlanders. An ultrasonographic investigation.

https://arctichealth.org/en/permalink/ahliterature5203
Source
Arctic Med Res. 1990 Jul;49(3):151-6
Publication Type
Article
Date
Jul-1990
Author
J P Hansen
S. Hancke
J. Møller-Petersen
Author Affiliation
Department of Pathology, Gentofte Hospital, University of Copenhagen, Denmark.
Source
Arctic Med Res. 1990 Jul;49(3):151-6
Date
Jul-1990
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Arteriosclerosis - ethnology - ultrasonography
Carotid Arteries - ultrasonography
Denmark - ethnology
Femoral Artery - ultrasonography
Greenland - ethnology
Humans
Inuits
Middle Aged
Abstract
A low frequency of ischemic heart disease in Eskimos (Inuit) has been regarded as an expression of absent or low atherosclerosis. The true extent of atherosclerosis in the Eskimo populations of the World is not known due to low autopsy activity. In order to register atherosclerotic changes in the carotid and femoral arteries 61 Native Greenlanders from two settlements with a traditional Eskimo life style in the Uummannaq district of Northwestern Greenland were examined ultrasonographically with a portable scanner (Aloka) using a 7.5 MHz 4 cm linear array transducer. The results obtained were compared to an age and sex matched urban control group of 122 Danes from Copenhagen. The investigation showed that the Native Greenlanders had almost the same degree and extent of atherosclerosis in the carotid and femoral arteries as the Danes. Thus, the low incidence of ischemic heart disease in Native Greenlanders may not be attributed to lesser atherosclerosis. Further studies, particularly autopsy studies are needed.
PubMed ID
2206175 View in PubMed
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Attempted suicide and violent criminality among Danish second-generation immigrants according to parental place of origin.

https://arctichealth.org/en/permalink/ahliterature277201
Source
Int J Soc Psychiatry. 2016 Mar;62(2):186-97
Publication Type
Article
Date
Mar-2016
Author
Roger T Webb
Sussie Antonsen
Carsten B Pedersen
Pearl L H Mok
Elizabeth Cantor-Graae
Esben Agerbo
Source
Int J Soc Psychiatry. 2016 Mar;62(2):186-97
Date
Mar-2016
Language
English
Publication Type
Article
Keywords
Acculturation
Adolescent
Adult
Africa - ethnology
Asia - ethnology
Child
Denmark
Emigrants and Immigrants - psychology
Europe - ethnology
Female
Greenland - ethnology
Humans
Incidence
Male
Middle Aged
Middle East - ethnology
Regression Analysis
Suicide, Attempted - ethnology
Violence - ethnology
Young Adult
Abstract
Immigrant populations in Western European countries have grown in their size and diversity, but little is known about risks of self-directed and externalised violence among second-generation immigrants.
To compare risks for attempted suicides and violent offending among second-generation immigrants to Denmark according to parental region of origin versus the native Danish population.
Data from interlinked national Danish registers were used (N?=?1,973,614). Parental origin outside Denmark was categorised thus: Asia, Africa, Middle East, Greenland, other Scandinavian countries, elsewhere in Europe and all other regions. We estimated gender-specific cumulative incidence and incidence rate ratios (IRRs) versus native Danes.
In virtually all subgroups of second-generation immigrants, risk was elevated for the two adverse outcomes in both genders. Females generally had greater elevations in attempted suicide risk, and males had greater elevations in violent offending risk. For attempted suicide, especially large IRRs were observed for males and females whose parents emigrated from Greenland; for violent offending, risks were particularly raised for males and females of Middle Eastern, Greenlandic and African origin. Adjustment for socioeconomic status partially explained these associations.
Western European nations should develop preventive programmes tailored towards specific second-generation immigrant populations, with integrated approaches jointly tackling suicidality and violence.
PubMed ID
26613752 View in PubMed
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Cancer pattern among Greenlandic Inuit migrants in Denmark, 1968-82.

https://arctichealth.org/en/permalink/ahliterature4175
Source
Pages 642-644 in H. Linderholm et al., eds. Circumpolar Health 87. Proceedings of the Seventh International Congress on Circumpolar Health, Umeå, Sweden, 1987. Arctic Medical Research. 1988;47 Supp 1.
Publication Type
Article
Date
1988
  1 document  
Author
Prener, A.
Nielsen, N.H.
Hansen, J.P.
Jensen, O.M.
Source
Pages 642-644 in H. Linderholm et al., eds. Circumpolar Health 87. Proceedings of the Seventh International Congress on Circumpolar Health, Umeå, Sweden, 1987. Arctic Medical Research. 1988;47 Supp 1.
Date
1988
Language
English
Geographic Location
Denmark
Publication Type
Article
Digital File Format
Text - PDF
Physical Holding
University of Alaska Anchorage
Keywords
Adult
Cross-Sectional Studies
Denmark - epidemiology
Emigration and Immigration
Female
Greenland - ethnology
Humans
Incidence
Inuits
Life Style
Male
Middle Aged
Neoplasms - epidemiology
Registries
Risk factors
PubMed ID
3272705 View in PubMed
Documents
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47 records – page 1 of 5.