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Assessment of laboratory methods for detection of unsuspected diabetes in primary health care.

https://arctichealth.org/en/permalink/ahliterature39232
Source
Scand J Prim Health Care. 1986 May;4(2):85-95
Publication Type
Article
Date
May-1986
Author
P O Bitzén
B. Scherstén
Source
Scand J Prim Health Care. 1986 May;4(2):85-95
Date
May-1986
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Ascorbic Acid - urine
Blood Glucose - analysis
Child
Child, Preschool
Diabetes Mellitus - blood - diagnosis - urine
False Negative Reactions
Fasting
Female
Glucose Tolerance Test
Glycosuria - diagnosis
Humans
Infant
Infant, Newborn
Male
Middle Aged
Reagent Strips - diagnostic use
Research Support, Non-U.S. Gov't
Abstract
In order to assess different methods for early detection of unsuspected diabetes, urine and venous blood samples were collected at random from 1082 patients visiting a primary health care centre in southern Sweden. Blood glucose was analysed by the hexokinase method along with the Dextrostix-Eyetone reflectance meter. Urine glucose was determined by Clinistix, Diastix, Neostix, Rediatest, Clinitest and quantitatively by the hexokinase method. Patients fulfilling the criteria of a positive screen were subjected to a diagnostic investigation with an oral glucose tolerance test. Out of 89 positive screenees, 37 patients were classified as diabetics, showing a prevalence of diabetes in the study population of 3.4% according to the WHO criteria. Impaired glucose tolerance was found in 14 patients. In a control group of 56 patients, randomly selected among negative screenees, no cases of diabetes were found. Random blood glucose measurement by the hexokinase method, using 7 mmol/l as a screening level, had a significantly higher sensitivity (95%) than all urine glucose methods (59-30%) with comparable specificity (97-99%). Use of the Dextrostix-Eyetone reflectance meter resulted in a decrease in sensitivity to 75% without any change in specificity or predictability, compared with the hexokinase method. Urine testing for glucose was found to be a suboptimal method for early case finding of diabetes among patients receiving primary health care.
PubMed ID
3726333 View in PubMed
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Blood glucose and diabetes mellitus in subjects aged 85 years or more.

https://arctichealth.org/en/permalink/ahliterature242421
Source
Acta Med Scand. 1983;214(3):239-44
Publication Type
Article
Date
1983
Author
M. Haavisto
K. Mattila
S. Rajala
Source
Acta Med Scand. 1983;214(3):239-44
Date
1983
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Blood Glucose - analysis
Diabetes Mellitus - blood - therapy
Female
Finland
Glycosuria
Humans
Male
Abstract
Blood and urine glucose values and the prevalence of diabetes mellitus were determined in the course of a health survey covering inhabitants of Tampere, Finland, aged 85 or over. Out of the total cohort, 561 (83%) subjects, of whom 82% were women, were examined. A high blood glucose level (greater than or equal to 7.0 mmol/l) was recorded in 10% of the males and 7% of the females. The prevalence of diabetes mellitus in the series was 17%. Five per cent of the total series were on drug treatment for their diabetes; 5% of the diabetics were on insulin therapy and 25% took oral antidiabetic drugs, while 70% were either on diet or had no treatment. Diabetes seems to be common among the very aged, but it is generally mild and easy to treat.
PubMed ID
6660031 View in PubMed
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Source
Archives of Environmental Health. 1969 Jan; 18:144-147.
Publication Type
Article
Date
1969
Author
Schaefer, O.
Author Affiliation
Northern Medical Research Laboratory (Edmonton)
Source
Archives of Environmental Health. 1969 Jan; 18:144-147.
Date
1969
Language
English
Geographic Location
Canada
Indigenous Groups
Inuit
Publication Type
Article
Physical Holding
Alaska Medical Library
Keywords
Pangnirtung
Coppermine
Holman
Eskimo Point
Glucose tolerance
Diet, western
Dietary Carbohydrates
Adolescent
Adult
Arctic Regions
Child
Child, Preschool
Sex Factors
Middle Aged
Male
Diabetes Mellitus - diagnosis - epidemiology
Female
Glycosuria - epidemiology
Glucose Tolerance Test
Notes
From: Fortuine, Robert et al. 1993. The Health of the Inuit of North America: A Bibliography from the Earliest Times through 1990. University of Alaska Anchorage. Citation number 980.
PubMed ID
5782493 View in PubMed
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City-wide screening for urinary abnormalities in schoolboys.

https://arctichealth.org/en/permalink/ahliterature253177
Source
Can Med Assoc J. 1974 Sep 7;111(5):410-2
Publication Type
Article
Date
Sep-7-1974
Author
D S Silverberg
Source
Can Med Assoc J. 1974 Sep 7;111(5):410-2
Date
Sep-7-1974
Language
English
Publication Type
Article
Keywords
Adolescent
Alberta
Bacteriological Techniques
Bacteriuria - diagnosis - epidemiology
Child
Child, Preschool
Costs and Cost Analysis
Diabetes Mellitus - diagnosis
Evaluation Studies as Topic
Glycosuria - diagnosis - epidemiology
Hematuria - diagnosis - epidemiology
Humans
Male
Mass Screening - methods
Proteinuria - diagnosis - epidemiology
Pyelonephritis - diagnosis
Reagent Strips
Urinary Tract Infections - diagnosis
Urography
Abstract
Screening for urinary tract infection was carried out in 27,722 schoolboys aged 5 to 14 using Uricult to perform urine cultures and Hema-combistix to detect hematuria, proteinuria and glycosuria. Cultures of 10(5) colonies per ml or more on two occasions were found in 40 cases (0.14%), but no case was confirmed by the family physician using standard culture techniques.Proteinuria was found in 136 cases (0.49%) and confirmed in 47 (37%) of the 126 children who were seen by their family physician. In this group 8.8% had evidence of pyelonephritic scarring on intravenous pyelograms without a positive urine culture.Hematuria was found in 19 children and confirmed in 10 (59%) of the 17 children who were seen by their family physician. No abnormalities were detected on intravenous pyelography in any case.Glycosuria was found in 12 cases and confirmed in five. Three of these children had renal glycosuria and two had previously undetected diabetes.
Notes
Cites: Br Med J. 1969 Jul 12;3(5662):81-45790270
Cites: Lancet. 1973 Jan 13;1(7794):94-54118664
Cites: Can Med Assoc J. 1973 Nov 17;109(10):981-54758869
Cites: J Am Med Assoc. 1958 Jun 14;167(7):807-1313549192
Cites: N Engl J Med. 1962 Jun 21;266:1287-9614460571
PubMed ID
4606340 View in PubMed
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City-wide screening for urinary abnormalities in schoolgirls.

https://arctichealth.org/en/permalink/ahliterature254182
Source
Can Med Assoc J. 1973 Nov 17;109(10):981-5
Publication Type
Article
Date
Nov-17-1973
Author
D S Silverberg
M J Allard
R A Ulan
W E Beamish
B C Lentle
M S McPhee
M G Grace
Source
Can Med Assoc J. 1973 Nov 17;109(10):981-5
Date
Nov-17-1973
Language
English
Publication Type
Article
Keywords
Adolescent
Alberta
Bacteriuria - diagnosis
Child
Child, Preschool
Costs and Cost Analysis
Cystitis - etiology
Cystoscopy
Diabetes Mellitus - urine
Female
Glycosuria - diagnosis
Hematuria - diagnosis
Humans
Hydronephrosis - etiology
Mass Screening
Proteinuria - diagnosis
Pyelonephritis - etiology
Pyuria - diagnosis
School Health Services
Ureteral Obstruction - etiology
Urinary Tract Infections - complications - diagnosis - epidemiology
Urography
Vesico-Ureteral Reflux - etiology
Abstract
Screening for urinary tract infection was carried out in 23,427 schoolgirls, aged 5 to 14 years, using Uricult and, for hematuria, glycosuria and proteinuria using Hema-combistix. Cultures of 10(5) colonies per ml. or more on two occasions were obtained in 2.3% and a positive culture was confirmed by the family physician using standard culture techniques in 82.7% of cases, giving an overall incidence of infection of 1.9%. Fifty-eight percent of these children had no previous history of any urinary tract symptoms. Of the infected group 9.5% had pyelonephritic scarring, 58.7% chronic cystitis and 58.7% urethral stenosis. Two additional cases had unilateral ureteropelvic junction obstruction with hydronephrosis. Reflux occurred in 26.6% of those investigated by voiding cystogram. In 58% of cases the urinary tract infection was not accompanied by significant proteinuria, hematuria or pyuria.Proteinuria was detected on two occasions in 1.6% of the children and confirmed by the family physician in 33% of cases, giving an overall incidence of 0.5%. In this group 9.2% had evidence of pyelonephritic scarring without a positive urine culture.Hematuria was detected on two occasions in 0.6% of the children and was confirmed by the family physician in 53%, giving an overall incidence of 0.3%. Only one case with pyelonephritic scarring was seen in this group.Of the 25 cases with pyelonephritic changes only six had been previously diagnosed radiologically.Four previously unrecognized diabetics were also detected.
Notes
Cites: Lancet. 1970 Jan 17;1(7638):119-214188726
Cites: Pediatr Clin North Am. 1971 May;18(2):509-284939562
Cites: Arch Dis Child. 1973 Jan;48(1):8-204685601
Cites: J Am Med Assoc. 1958 Jun 14;167(7):807-1313549192
PubMed ID
4758869 View in PubMed
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[Comparative action of Pyatigorsk health resort factors on diabetes mellitus patients].

https://arctichealth.org/en/permalink/ahliterature246731
Source
Vopr Kurortol Fizioter Lech Fiz Kult. 1979 Nov-Dec;(6):47-50
Publication Type
Article

The control of diabetes in summer campers, with special reference to acetone bodies.

https://arctichealth.org/en/permalink/ahliterature109955
Source
Diabetologia. 1969 Aug;5(4):233-7
Publication Type
Article
Date
Aug-1969

A cross-sectional study of dietary habits and urinary glucose excretion - a predictor of non-insulin-dependent diabetes mellitus.

https://arctichealth.org/en/permalink/ahliterature20439
Source
Eur J Clin Nutr. 2000 May;54(5):434-9
Publication Type
Article
Date
May-2000
Author
A. Ekblond
L. Mellemkjaer
A. Tjonneland
M. Suntum
C. Stripp
K. Overvad
C. Johansen
J H Olsen
Author Affiliation
Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark.
Source
Eur J Clin Nutr. 2000 May;54(5):434-9
Date
May-2000
Language
English
Publication Type
Article
Keywords
Animals
Cereals
Cross-Sectional Studies
Denmark
Diabetes Mellitus, Type 2 - etiology - prevention & control - urine
Diet
Dietary Fiber - administration & dosage
Female
Fishes
Fruit
Glycosuria
Humans
Male
Middle Aged
Milk
Poultry
Research Support, Non-U.S. Gov't
Sex Characteristics
Abstract
OBJECTIVE: To investigate the association between consumption of certain foods and macronutrients and urinary glucose excretion, which is a predictor of non-insulin-dependent diabetes mellitus. DESIGN: A cross-sectional study, Denmark, 1993-97. SUBJECTS: Participants in the Danish study 'Diet, Cancer and Health'. After exclusion of persons with postprandial urine samples and persons with diabetes or other diseases potentially resulting in glycosuria, the study population included 14 743 men and 18 064 women aged 50-64 y. We identified 183 men and 43 women with glucose in their urine. RESULTS: Consumption of poultry was negatively associated with glycosuria in both men (odds ratio, OR=0.87; 95% confidence interval, 95% CI=0.77-0.98) and women (OR=0.69; 0.48-1.00). Fiber from fruit showed a weak negative association with glycosuria in both men (0. 95; 0.90-1.01) and women (0.89; 0.78-1.02), whereas a significant negative association with total fiber (0.68; 0.51-0.91) and fiber from vegetables (0.94; 0.88-0.99) was seen in men. Intake of fish tended to reduce the risk of glycosuria in women only (0.80; 0.63-1. 02), whereas ingestion of milk products increased their risk significantly (1.15; 1.06-1.24). CONCLUSION: Although statistical significance and consistency in the two sexes were not achieved for all end-points, the study indicates a protective effect of dietary products like poultry, fruit and cereals against glycosuria and suggests a promoting effect of milk. SPONSORSHIP: The Danish National Board of Health and the Danish Cancer Society.
PubMed ID
10822293 View in PubMed
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