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Classification and pathology of gastroenteropancreatic neuroendocrine neoplasms.

https://arctichealth.org/en/permalink/ahliterature130234
Source
Endocr Relat Cancer. 2011 Oct;18 Suppl 1:S1-16
Publication Type
Article
Date
Oct-2011
Author
Günter Klöppel
Author Affiliation
Department of Pathology, Technical University of München, Ismaninger Strasse 22, 81675 München, Germany. guenter.kloeppel@alumni.uni-kiel.de
Source
Endocr Relat Cancer. 2011 Oct;18 Suppl 1:S1-16
Date
Oct-2011
Language
English
Publication Type
Article
Keywords
Gastrointestinal Neoplasms - classification - pathology - therapy
Humans
Neuroendocrine Tumors - classification - pathology - therapy
Pancreatic Neoplasms - classification - pathology - therapy
World Health Organization
Abstract
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are composed of cells with a neuroendocrine phenotype. The old and the new WHO classifications distinguish between well-differentiated and poorly differentiated neoplasms. All well-differentiated neoplasms, regardless of whether they behave benignly or develop metastases, will be called neuroendocrine tumours (NETs), and graded G1 (Ki67 20%). To stratify the GEP-NETs and GEP-NECs regarding their prognosis, they are now further classified according to TNM-stage systems that were recently proposed by the European Neuroendocrine Tumour Society (ENETS) and the AJCC/UICC. In the light of these criteria the pathology and biology of the various NETs and NECs of the gastrointestinal tract (including the oesophagus) and the pancreas are reviewed.
PubMed ID
22005112 View in PubMed
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The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement.

https://arctichealth.org/en/permalink/ahliterature143977
Source
Virchows Arch. 2010 Jun;456(6):595-7
Publication Type
Article
Date
Jun-2010

Gastroenteric neuroendocrine neoplasms classification: comparison of prognostic models.

https://arctichealth.org/en/permalink/ahliterature123006
Source
Cancer. 2013 Jan 1;119(1):36-44
Publication Type
Article
Date
Jan-1-2013
Author
Anna Dolcetta-Capuzzo
Valentina Villa
Luca Albarello
Giulia M Franchi
Marco Gemma
Marina Scavini
Saverio Di Palo
Elena Orsenigo
Emanuele Bosi
Claudio Doglioni
Marco F Manzoni
Author Affiliation
Department of Endocrinology and Internal Medicine, Endocrine Tumors Unit, San Raffaele Scientific Institute, Milan, Italy.
Source
Cancer. 2013 Jan 1;119(1):36-44
Date
Jan-1-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Female
Gastrointestinal Neoplasms - classification - pathology
Humans
Male
Middle Aged
Models, Statistical
Neoplasm Grading
Neoplasm Staging
Neuroendocrine Tumors - classification - pathology
Prognosis
Survival Analysis
Abstract
Gastroenteric neuroendocrine neoplasms (GE-NENs) display highly variable clinical behavior. In an attempt to assess a better prognostic description, in 2010, the World Health Organization (WHO) updated its previous classification, and the European Neuroendocrine Tumors Society (ENETS) proposed a new grading and TNM-based staging system. In the current study, the authors evaluated the prognostic significance of these models and compared their efficacy in describing patients' long-term survival to assess the best prognostic model currently available for clinicians.
The study cohort was composed of 145 patients with extrapancreatic GE-NEN who were observed from 1986 to 2008 at a single center and were classified according to the WHO and ENETS classifications. Survival evaluations were performed using Kaplan-Meyer analyses on 131 patients. Only deaths from neoplasia were considered. A P value
PubMed ID
22744914 View in PubMed
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[The ENETS and UICC TNM classification of neuroendocrine tumors of the gastrointestinal tract and the pancreas: comment].

https://arctichealth.org/en/permalink/ahliterature141104
Source
Pathologe. 2010 Sep;31(5):353-4
Publication Type
Article
Date
Sep-2010
Author
G. Klöppel
G. Rindi
A. Perren
P. Komminoth
D S Klimstra
Author Affiliation
Konsultationszentrum für Pankreas und Endokrine Tumoren, Institut für Pathologie, Technische Universität München, Ismaningerstr. 22, 81675, München, Deutschland. guenter.kloeppel@alumni.uni-kiel.de
Source
Pathologe. 2010 Sep;31(5):353-4
Date
Sep-2010
Language
German
Publication Type
Article
Keywords
Carcinoid Tumor - classification - pathology
Consensus
Gastrointestinal Neoplasms - classification - pathology
Humans
Neoplasm Invasiveness - pathology
Neoplasm Staging - methods
Neuroendocrine Tumors - classification - pathology
Pancreatic Neoplasms - classification - pathology
Prognosis
Societies, Medical
Notes
Comment On: Pathologe. 2010 Sep;31(5):348-5220798945
PubMed ID
20809402 View in PubMed
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