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44 records – page 1 of 5.

[Acute insufficiency of the gastrointestinal tract in patients with severe gunshot injury].

https://arctichealth.org/en/permalink/ahliterature191604
Source
Vestn Khir Im I I Grek. 2001;160(5):89-93
Publication Type
Article
Date
2001
Author
S V Gavrilin
G L Gerasimov
V V Boiarintsev
V F Lebedev
M G Kobiashvili
V G Fedorov
G E Ivanovskii
Source
Vestn Khir Im I I Grek. 2001;160(5):89-93
Date
2001
Language
Russian
Publication Type
Article
Keywords
Abdominal Injuries - complications - therapy
Acute Disease
Adult
Female
Gastrointestinal Diseases - etiology
Humans
Male
Multiple Organ Failure - etiology
Risk factors
Russia
War
Wounds, Gunshot - complications - therapy
Abstract
Acute insufficiency of the gastrointestinal tract (GIT) in patients with severe gunshot injuries is an important link of pathogenesis of the polyorganic insufficiency syndrome. The character of the wound, the numerical score objective assessment of the injury severity and severity of the patient's state are considered to be criteria of early diagnosis of a risk of the development of acute insufficiency of GIT. The specific feature of "general" intensive therapy of acute insufficiency of GIT in severe gunshot traumas is the necessary application of regional anesthesia, sympatholytics, anticholinesterase agents and H2-blockers. Intensive "enteral" therapy of acute insufficiency of GIT in severe gunshot wounds includes the measures resulting in improvement of microcirculation, tissue respiration in organs of GIT, decompression of the stomach, local defense of mucosa, detoxication and early enteral balanced nutrition. The described method of treatment of wounded to the stomach used at specialized medical institutions resulted in 6.2 less lethality among this category of patients.
PubMed ID
11837007 View in PubMed
Less detail

Adverse reactions from consumption of oral rabies vaccine baits in dogs in Finland.

https://arctichealth.org/en/permalink/ahliterature279089
Source
Acta Vet Scand. 2016 Sep 15;58(1):53
Publication Type
Article
Date
Sep-15-2016
Author
Tiina Nokireki
Martti Nevalainen
Liisa Sihvonen
Tuija Gadd
Source
Acta Vet Scand. 2016 Sep 15;58(1):53
Date
Sep-15-2016
Language
English
Publication Type
Article
Keywords
Animals
Behavior, Animal - drug effects
Dog Diseases - etiology - pathology
Dogs
Finland
Gastrointestinal Diseases - etiology - veterinary
Rabies Vaccines - adverse effects - pharmacology
Vaccination - adverse effects - veterinary
Abstract
Oral rabies vaccination of wildlife has effectively reduced the incidence of rabies in wildlife and has led to the elimination of rabies in large areas of Europe. The safety of oral rabies vaccines has been assessed in both target (red fox and raccoon dog) and several non-target species.
Since 2011, the competent authority in Finland has received a few reports of dogs experiencing adverse reactions that have been assumed to be caused by the consumption of baits containing oral rabies vaccine. The dogs usually exhibited gastrointestinal symptoms (vomiting, inappetence, constipation or diarrhoea) or behavioral symptoms (restlessness, listlessness and unwillingness to continue hunting).
Nevertheless, these adverse reactions are transient and non-life threatening. Even though the adverse reactions are unpleasant to individual dogs and their owners, the benefits of oral rabies vaccination clearly outweigh the risks.
PubMed ID
27633386 View in PubMed
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Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Human C1q Deficiency: The Karolinska Experience.

https://arctichealth.org/en/permalink/ahliterature283107
Source
Transplantation. 2016 Jun;100(6):1356-62
Publication Type
Article
Date
Jun-2016
Author
Richard F Olsson
Stefan Hagelberg
Bodil Schiller
Olle Ringdén
Lennart Truedsson
Anders Åhlin
Source
Transplantation. 2016 Jun;100(6):1356-62
Date
Jun-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Child
Child, Preschool
Complement C1q - deficiency
Cortisone - adverse effects
Cyclosporine - administration & dosage
Fatal Outcome
Female
Gastrointestinal Diseases - etiology - mortality
Graft vs Host Disease - etiology
Hematopoietic Stem Cell Transplantation - adverse effects
Heterozygote
Humans
Infant
Iraq
Lupus Erythematosus, Systemic - therapy
Lymphoproliferative Disorders - etiology
Male
Methotrexate - administration & dosage
Postoperative Complications
Rituximab - administration & dosage
Sweden
Time Factors
Transplantation Conditioning - methods
Transplantation, Homologous - adverse effects
Treatment Outcome
Abstract
Human C1q deficiency is associated with systemic lupus erythematosus (SLE) and increased susceptibility to severe bacterial infections. These patients require extensive medical therapy and some develop treatment-resistant disease. Because C1q is produced by monocytes, it has been speculated that allogeneic hematopoietic stem cell transplantation (allo-HSCT) may cure this disorder.
We have so far treated 5 patients with C1q deficiency. In 3 cases, SLE symptoms remained relatively mild after the start of medical therapy, but 2 patients developed treatment-resistant SLE, and we decided to pursue treatment with allo-HSCT. For this purpose, we chose a conditioning regimen composed of treosulfan (14 g/m) and fludarabine (30 mg/m) started on day -6 and given for 3 and 5 consecutive days, respectively. Thymoglobulin was given at a cumulative dose of 8 mg/kg, and graft-versus-host disease prophylaxis was composed of cyclosporine and methotrexate.
A 9-year-old boy and a 12-year-old girl with refractory SLE restored C1q production after allo-HSCT. This resulted in normal functional properties of the classical complement pathway followed by reduced severity of SLE symptoms. The boy developed posttransplant lymphoproliferative disease, which resolved after treatment with rituximab and donor lymphocyte infusion. Unfortunately, donor lymphocyte infusion induced severe cortisone-resistant gastrointestinal graft-versus-host disease, and the patient died from multiple organ failure 4 months after transplantation. The girl is doing well 33 months after transplantation, and clinically, all signs of SLE have resolved.
Allo-HSCT can cure SLE in human C1q deficiency and should be considered early in subjects resistant to medical therapy.
PubMed ID
26516671 View in PubMed
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Anaerobic infections in children with neurological impairments.

https://arctichealth.org/en/permalink/ahliterature215267
Source
Am J Ment Retard. 1995 May;99(6):579-94
Publication Type
Article
Date
May-1995
Author
I. Brook
Author Affiliation
Georgetown University School of Medicine, USA.
Source
Am J Ment Retard. 1995 May;99(6):579-94
Date
May-1995
Language
English
Publication Type
Article
Keywords
Bacteria, Anaerobic - isolation & purification - pathogenicity
Brain Diseases - complications - etiology
Child Welfare
Child, Preschool
Gastrointestinal Diseases - etiology - microbiology - surgery
Gastrostomy
Humans
Immune System - physiology
Infant
Lung Diseases - microbiology
Osteomyelitis - etiology
Otitis Media with Effusion - diagnosis - microbiology
Parenteral Nutrition
Pressure Ulcer - complications - diagnosis - microbiology
Abstract
Children with neurological impairments are prone to develop serious infection due to anaerobic bacteria. They often are predisposed to develop infections caused by their own indigenous bacterial flora caused by impairments of their mechanical and immunological defenses, the change in their oral flora due to poor hygiene, and the delay in recognition of acute infection. The most common anaerobic infections are decubitus ulcers, gastrectomy site wound infections, pulmonary infections (aspiration pneumonia, lung abscesses, and tracheitis), and chronic suppurative otitis media. The unique microbiology of each of the infections and their medical and surgical management were discussed in this review.
PubMed ID
7632426 View in PubMed
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An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid.

https://arctichealth.org/en/permalink/ahliterature228853
Source
N Engl J Med. 1990 Jun 21;322(25):1775-80
Publication Type
Article
Date
Jun-21-1990
Author
T M Perl
L. Bédard
T. Kosatsky
J C Hockin
E C Todd
R S Remis
Author Affiliation
Bureau régional des maladies infectieuses, Montreal, PQ, Canada.
Source
N Engl J Med. 1990 Jun 21;322(25):1775-80
Date
Jun-21-1990
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Animals
Bivalvia
Brain Diseases - chemically induced
Canada
Disease Outbreaks
Female
Follow-Up Studies
Food Contamination
Foodborne Diseases - etiology
Gastrointestinal Diseases - etiology
Humans
Kainic Acid - analogs & derivatives - poisoning
Male
Marine Toxins - poisoning
Memory Disorders - etiology
Middle Aged
Neurotransmitter Agents - poisoning
Prince Edward Island
Sex Factors
Abstract
In Canada in late 1987 there was an outbreak of an acute illness characterized by gastrointestinal symptoms and unusual neurologic abnormalities among persons who had eaten cultivated mussels. Health departments in Canada solicited reports of this newly recognized illness. A case was defined as the occurrence of gastrointestinal symptoms within 24 hours or of neurologic symptoms within 48 hours of the ingestion of mussels. From the more than 250 reports received, 107 patients met the case definition. The most common symptoms were vomiting (in 76 percent of the patients), abdominal cramps (50 percent), diarrhea (42 percent), headache, often described as incapacitating (43 percent), and loss of short-term memory (25 percent). Nineteen patients were hospitalized, of whom 12 required intensive care because of seizures, coma, profuse respiratory secretions, or unstable blood pressure. Male sex and increasing age were associated independently with the risks of hospitalization and memory loss. Three patients died. Mussels associated with this illness were traced to cultivation beds in three river estuaries on the eastern coast of Prince Edward Island. Domoic acid, which can act as an excitatory neurotransmitter, was identified in mussels left uneaten by the patients and in mussels sampled from these estuaries. The source of the domoic acid appears to have been a form of marine vegetation, Nitzschia pungens, also identified in these waters in late 1987. The contaminated mussels from Prince Edward Island were removed from the market, and no new cases have occurred since December 1987. We conclude that the cause of this outbreak of a novel and severe intoxication was the ingestion of mussels contaminated by domoic acid, a potent excitatory neurotransmitter.
Notes
Comment In: N Engl J Med. 1990 Dec 6;323(23):1631-32073268
PubMed ID
1971709 View in PubMed
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[A peaceful Christmas Eve at the hospital].

https://arctichealth.org/en/permalink/ahliterature129099
Source
Ugeskr Laeger. 2011 Dec 5;173(49):3178-81
Publication Type
Article
Date
Dec-5-2011
Author
Ramshanker Ramanathan
Mikkel Brabrand
Lars Folkestad
Peter Hallas
Author Affiliation
Medicinsk Afdeling, Sydvestjysk Sygehus Esbjerg, Denmark. diinnar@hotmail.com
Source
Ugeskr Laeger. 2011 Dec 5;173(49):3178-81
Date
Dec-5-2011
Language
Danish
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Denmark - epidemiology
Feeding Behavior
Female
Gastrointestinal Diseases - etiology - mortality
Heart Diseases - etiology - mortality
Holidays
Humans
Hyperphagia - complications
Male
Middle Aged
Patient Admission - statistics & numerical data
Registries
Retrospective Studies
Social Support
Workload
Abstract
The aim of this study was to investigate admittance rates and doctors workload during Christmas. In addition, we examined if admittance data supports the common notions that overeating during Christmas results in increased rate of admittances for abdominal problems and that there is an increase in admittance of the elderly at the end of Christmas (i.e. "granny dumping").
A retrospective study analyzing data from the database of the hospital units of Sydvestjysk Sygehus was performed. Data covered admittance in the months spanning from November through January in 1994-2010. Data from Christmas was compared with data from adjacent months.
During Christmas more patients with abdominal complaints were admitted to the hospital (p
PubMed ID
22142604 View in PubMed
Less detail

[Current problems in the etiology and pathogenesis of acute digestive disorders in nursing infants]

https://arctichealth.org/en/permalink/ahliterature60964
Source
Pediatr Akus Ginekol. 1974 Jul-Aug;(4):6-7
Publication Type
Article

Effects of a 20 year rain event: a quantitative microbial risk assessment of a case of contaminated bathing water in Copenhagen, Denmark.

https://arctichealth.org/en/permalink/ahliterature105695
Source
J Water Health. 2013 Dec;11(4):636-46
Publication Type
Article
Date
Dec-2013
Author
S T Andersen
A C Erichsen
O. Mark
H-J Albrechtsen
Author Affiliation
Department of Environmental Engineering, Technical University of Denmark (DTU), Miljoevej, Building 113, 2800 Kgs. Lyngby, Denmark E-mail: sita@env.dtu.dk.
Source
J Water Health. 2013 Dec;11(4):636-46
Date
Dec-2013
Language
English
Publication Type
Article
Keywords
Bathing Beaches - standards
Denmark
Environmental monitoring
Gastrointestinal Diseases - etiology - microbiology
Humans
Rain
Risk assessment
Sewage
Sports
Time Factors
Water Microbiology
Water Pollution
Abstract
Quantitative microbial risk assessments (QMRAs) often lack data on water quality leading to great uncertainty in the QMRA because of the many assumptions. The quantity of waste water contamination was estimated and included in a QMRA on an extreme rain event leading to combined sewer overflow (CSO) to bathing water where an ironman competition later took place. Two dynamic models, (1) a drainage model and (2) a 3D hydrodynamic model, estimated the dilution of waste water from source to recipient. The drainage model estimated that 2.6% of waste water was left in the system before CSO and the hydrodynamic model estimated that 4.8% of the recipient bathing water came from the CSO, so on average there was 0.13% of waste water in the bathing water during the ironman competition. The total estimated incidence rate from a conservative estimate of the pathogenic load of five reference pathogens was 42%, comparable to 55% in an epidemiological study of the case. The combination of applying dynamic models and exposure data led to an improved QMRA that included an estimate of the dilution factor. This approach has not been described previously.
PubMed ID
24334838 View in PubMed
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44 records – page 1 of 5.