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142 records – page 1 of 15.

[Action of gamma irradiation on the infectivity of the potato virus X, the TMV and their RNAs]

https://arctichealth.org/en/permalink/ahliterature69126
Source
Mikrobiol Zh. 1976 Jan-Feb;38(1):78-80
Publication Type
Article

[Activity of glutathione-dependent antioxidant system of the rat liver and blood depending on gamma-irradiation and diet]

https://arctichealth.org/en/permalink/ahliterature89398
Source
Ukr Biokhim Zh. 2008 Nov-Dec;80(6):66-73
Publication Type
Article
Author
Nikitchenko Iu V
Padalko V I
Tkachenko V M
Sheremet H O
Tovstiak V V
Source
Ukr Biokhim Zh. 2008 Nov-Dec;80(6):66-73
Language
Ukrainian
Publication Type
Article
Keywords
Animals
Antioxidants - metabolism
Diet
Dietary Supplements
Gamma Rays
Glutathione Peroxidase - blood - metabolism
Glutathione Transferase - blood - metabolism
Liver - enzymology - metabolism - radiation effects
Male
Microsomes, Liver - enzymology - metabolism - radiation effects
Mitochondria, Liver - enzymology - metabolism - radiation effects
Photinia - chemistry
Plant Extracts - administration & dosage - isolation & purification - therapeutic use
Radiation Injuries, Experimental - blood - metabolism - prevention & control
Rats
Rats, Wistar
Abstract
The role of the glutathione-dependent antioxidant system in the prooxidant-antioxidant balance support was studied in the experiments with Wistar male rat under single gamma-irradiation (8 Gr dose), fed with unbalanced (as to animal proteins and antioxidant vitamins) diet and with addition of Aronia melanocarpa. Single gamma-irradiation of animals led to the decrease of selenium-dependent glutathione-peroxidase activity in the blood plasma and glutathione-S-transferase activity decrease in rat liver mitochondria. Animals which received the unbalanced food allowance under irradiation showed more expressed change of glutathione-dependent antioxidant enzymes activity, namely--proved decrease of glutathione-peroxidase and glutathione-S-transferase activity in liver microsomes and less expressed activation of selenium-dependent glutathione-peroxidase activity in the postmitochondrial fraction of laboratory animals liver. Introduction of the A. melanocarpa food supplement in the unbalanced diet of the laboratory animals which in vitro demonstrated expressed antioxidant and antiradical activity had no effect upon glutathione-peroxidase activity in the investigated tissues. Obtained data concerning significant decrease of the activity of glutathione-dependent antioxidant system and, particularly, of the selenium-dependent glutathione-peroxidase activity under the unbalanced diet condition may be useful in maintenance of prooxidant-antioxidant balance in the tissues of irradiated animals. Allowing for the above stated it is advisable to seek for new food additives which increase activity of the endogenous glutathione-dependent antioxidant enzymes for human tolerance improvement, especially under the unbalanced food allowance condition.
PubMed ID
19351059 View in PubMed
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Acute myeloid leukemia and background radiation in an expanded case-referent study.

https://arctichealth.org/en/permalink/ahliterature25084
Source
Arch Environ Health. 1990 Nov-Dec;45(6):364-6
Publication Type
Article
Author
U. Flodin
M. Fredriksson
B. Persson
O. Axelson
Author Affiliation
Department of Occupational Medicine, University Hospital, Linkoping, Sweden.
Source
Arch Environ Health. 1990 Nov-Dec;45(6):364-6
Language
English
Publication Type
Article
Keywords
Acute Disease
Adult
Aged
Case-Control Studies
Environmental Exposure
Gamma Rays - adverse effects
Humans
Leukemia, Myeloid - epidemiology - etiology
Leukemia, Radiation-Induced - epidemiology - etiology
Middle Aged
Risk factors
Sweden - epidemiology
Abstract
A case-referent study that investigated possible associations between environmental and occupational exposures and acute myeloid leukemia was performed on 86 cases and 172 referents, all of whom were living. Exposure information was obtained through a questionnaire mailed to each subject. An association was found between time spent in concrete buildings at home and work and leukemia morbidity. In addition, extensive x-ray examinations that occurred more than 5 y prior to diagnosis were more common among cases than referents.
PubMed ID
2270956 View in PubMed
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Alterations in adenylate ratios in plant cells after accelerated ion irradiation.

https://arctichealth.org/en/permalink/ahliterature69076
Source
Adv Space Res. 1996;18(1-2):59-62
Publication Type
Article
Date
1996
Author
A. Vasilenko
P G Sidorenko
Author Affiliation
Institute of Botany, Ukranian National Academy of Sciences, Kyiv, Ukraine.
Source
Adv Space Res. 1996;18(1-2):59-62
Date
1996
Language
English
Publication Type
Article
Keywords
Adenosine Diphosphate - metabolism - radiation effects
Adenosine Triphosphate - metabolism - radiation effects
Cobalt Radioisotopes
Cyclotrons
Dose-Response Relationship, Radiation
Gamma Rays
Helium
Ions
Microscopy, Electron
Mitochondria - radiation effects - ultrastructure
Peas - cytology - metabolism - radiation effects - ultrastructure
Plant Roots - cytology - metabolism - radiation effects - ultrastructure
Plants, Toxic
Tobacco - cytology - metabolism - radiation effects - ultrastructure
Abstract
Levels of adenylate metabolism have been studied in cells of Nicotiana tabacum growing in vitro, and in root apex extracts of Pisum sativum irradiated at the 95-in. isochronous cyclotron U-240, Institute for Nuclear Research, Ukrainian National Academy of Sciences, Kyiv. Particle beams of accelerated helium ions with energy 9.34 keV/micrometer were used. Replacement and rapid freezing of the irradiated plants samples in liquid nitrogen were carried out with a manipulator and a remote control system. After doses of 5, 20, 50, and 100 Gy of gamma-irradiation, as well as 50 and 100 Gy 4He irradiation, the cellular ATP/ADP ratio increased during early stages of the response. This effect was absent at higher doses and after exposure to sparesly-ionizing radiation, when a rapid decline in the cellular ATP concentration and the ATP/ADP ratio occurred.
PubMed ID
11538989 View in PubMed
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Amchitka Island, Alaska: Special Sampling project, 1997.

https://arctichealth.org/en/permalink/ahliterature301435
Source
U.S. Department of Energy. Environmental Restoration Division. Nevada Operations Office. 57 pages.
Publication Type
Report
Date
July 2000
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-7 2.3 Sample Preparation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-14 3.0 Analytical Results . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3-1 3.1 Gamma-Ray Analytical Results
  1 document  
Source
U.S. Department of Energy. Environmental Restoration Division. Nevada Operations Office. 57 pages.
Date
July 2000
Language
English
Geographic Location
U.S.
Publication Type
Report
File Size
1551791
Keywords
Alaska
Amchitka
Cannikin
Milrow
Long Shot
Gamma-ray
Thermal Ionization Mass Spectrometry (TIMS)
Tritium
Surface water
Abstract
EPA-R&IE’s routine surveillance of ground and surface waters under the LTHMP was expanded for 1997 to include selected sampling of aquatic biota and sediments based on decisions of the Amchitka Technical Advisory Group (ATAG). The additional samples were collected from streams, lakes, seeps, and marine tidal areas within the surface drainage basins surrounding surface ground zero (SGZ) at each of the three test sites. Aquatic plants and sediments from a geographically similar reference area in the central part of the island were also collected. Lichens were sampled at one location on Amchitka Island and on Adak Island (about 300 km [188 miles (mi)] ESE of Amchitka) to provide data on worldwide fallout deposition on surface environments.
Notes
Nevada Environmental Restoration Project.
Documents
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Analysis of symmetrical translocations for retrospective biodosimetry in radiation workers of the Mayak nuclear-industrial complex (Southern Urals) using FISH-chromosome painting.

https://arctichealth.org/en/permalink/ahliterature204096
Source
Int J Radiat Biol. 1998 Oct;74(4):431-9
Publication Type
Article
Date
Oct-1998
Author
K. Salassidis
H. Braselmann
N D Okladnikova
S. Pressl
G. Stephan
G. Snigiryova
M. Bauchinger
Author Affiliation
GSF-National Research Center for Environment and Health, Institute of Radiobiology, Neuherberg, Germany.
Source
Int J Radiat Biol. 1998 Oct;74(4):431-9
Date
Oct-1998
Language
English
Publication Type
Article
Keywords
Aged
Chromosome Aberrations
Chromosomes - radiation effects
Dose-Response Relationship, Radiation
Female
Gamma Rays - adverse effects
Humans
In Situ Hybridization, Fluorescence
Lymphocytes
Male
Middle Aged
Neoplasms - etiology
Occupational Diseases
Occupational Exposure
Plutonium - toxicity
Radiometry
Retrospective Studies
Russia
Translocation, Genetic - genetics
Abstract
Frequencies of symmetrical translocations were determined by fluorescence in situ hybridization (FISH) for retrospective biodosimetry in workers occupationally exposed to external gamma-rays and internal plutonium at the Mayak nuclear-industrial complex (Southern Urals, Russia).
Chromosome analyses were carried out on peripheral lymphocytes from 75 Mayak workers who had received their main exposures between 1948 and 1963. Cumulative external gamma-ray doses between 0.02 and 9.91 Sv and plutonium burdens ranging between 0.26 and 18.5 kBq are reported. As controls, 33 unexposed persons from non-contaminated areas of the Southern Urals were used. Whole-chromosome painting probes for chromosomes 1, 4 and 12 were used simultaneously with a pancentromeric probe.
Compared with the control group, a significantly elevated translocation frequency was found for the total study group and for either of two subsets with (48 subjects) and without (27 subjects) plutonium incorporation. The dicentric frequency was not significantly different from the control level. In the pooled data set, translocation frequencies showed a significant dependence on cumulative external gamma-ray doses. Plutonium uptake had no substantial influence. Individual dose estimates for 21 cases exhibiting at least five translocations ranged between 0.5 and 1.8 Gy, which is substantially lower than the workers' registered personal doses.
At 35-40 years after protracted exposure to low-dose rate external gamma-rays, the postulated lifetime stability of translocations cannot be confirmed. Apparently, the natural loss of translocation-bearing peripheral lymphocytes cannot be fully compensated so that a temporal decline even of transmissible aberrations takes place. As a consequence, individual retrospective biodosimetry estimates cannot be obtained reliably from the remaining fraction of translocations.
PubMed ID
9798953 View in PubMed
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An update on thoron exposure in Canada with simultaneous ²²²Rn and ²²°Rn measurements in Fredericton and Halifax.

https://arctichealth.org/en/permalink/ahliterature138032
Source
Radiat Prot Dosimetry. 2011 Nov;147(4):541-7
Publication Type
Article
Date
Nov-2011
Author
Jing Chen
Deborah Moir
Toon Pronk
Terry Goodwin
Miroslaw Janik
Shinji Tokonami
Author Affiliation
Radiation Protection Bureau, Health Canada, 775 Brookfield Road, Ottawa, Canada. jing.chen@hc-sc.gc.ca
Source
Radiat Prot Dosimetry. 2011 Nov;147(4):541-7
Date
Nov-2011
Language
English
Publication Type
Article
Keywords
Air Pollutants, Radioactive - analysis
Air Pollution, Indoor - analysis
Canada
Environmental Exposure - analysis
Gamma Rays
Housing
Humans
Radiation monitoring
Radon - analysis
Radon Daughters - analysis
Abstract
Naturally occurring isotopes of radon in indoor air are identified as the second leading cause of lung cancer after tobacco smoking. Radon-222 (radon gas) and radon-220 (thoron gas) are the most common isotopes of radon. While extensive radon surveys have been conducted, indoor thoron data are very limited. To better assess thoron exposure in Canada, radon/thoron discriminating detectors were deployed in 45 homes in Fredericton and 65 homes in Halifax for a period of 3 months. In this study, radon concentrations ranged from 16 to 1374 Bq m(-3) with a geometric mean (GM) of 82 Bq m(-3) and a geometric standard deviation (GSD) of 2.56 in Fredericton, and from 4 to 2341 Bq m(-3) with a GM of 107 Bq m(-3) and a GSD of 3.67 in Halifax. It is estimated that 18 % of Fredericton homes and 32 % of Halifax homes could have radon concentrations above the Canadian indoor radon guideline of 200 Bq m(-3). This conclusion is significantly higher than the previous estimates made 30 y ago with short-term radon measurements. Thoron concentrations were below the detection limit in 62 % of homes in both cities. Among the homes with detectable thoron concentrations, the values varied from 12 to 1977 Bq m(-3) in Fredericton and from 6 to 206 Bq m(-3) in Halifax. The GM and GSD were 86 Bq m(-3) and 3.19 for Fredericton, and 35 Bq m(-3) and 2.35 for Halifax, respectively. On the basis of these results, together with previous measurements in Ottawa, Winnipeg and the Mont-Laurier region of Quebec, it is estimated that thoron contributes ~8 % of the radiation dose due to indoor radon exposure in Canada.
PubMed ID
21216734 View in PubMed
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Assessment of external dose to inhabitants evacuated from the 30-km zone soon after the Chernobyl accident.

https://arctichealth.org/en/permalink/ahliterature46143
Source
Radiats Biol Radioecol. 2000 Sep-Oct;40(5):582-8
Publication Type
Article
Author
T. Imanaka
H. Koide
Author Affiliation
Research Reactor Institute, Kyoto University, Kumatori-cho, Osaka 590-0494, Japan. imanaka@rri.kyoto-u.ac.jp
Source
Radiats Biol Radioecol. 2000 Sep-Oct;40(5):582-8
Language
English
Publication Type
Article
Keywords
Accidents, Radiation
Disaster planning
Gamma Rays
Humans
Power Plants
Radiation Injuries - epidemiology
Research Support, Non-U.S. Gov't
Ukraine - epidemiology
Abstract
According to reports by the former USSR government, IAEA and WHO, no case of acute radiation effects was recognized among inhabitants who were evacuated from the 30-km zone around the Chernobyl site soon after the accident on April 26, 1986. Along with the collapse of the USSR, however, several documents appeared that report the occurrence of acute radiation effects among inhabitants. In order to check the possibility of acute radiation effects among evacuees, we evaluated the external dose of evacuees until their evacuation based on the data about the radiation situation soon after the accident. Our estimates indicate that a substantial number of inhabitants in some villages could have received more than 0.5 Sv that is recognized by ICRP and UNSCEAR as a threshold dose for a clinically significant depression of the blood-forming function of bone marrow. Some of them could have received more than 1 Sv.
PubMed ID
11130948 View in PubMed
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[Association of pulmonary tuberculosis morbidity with local earth's crustal fractures on the territory of a contemporary industrial town]

https://arctichealth.org/en/permalink/ahliterature29896
Source
Probl Tuberk Bolezn Legk. 2004;(12):44-7
Publication Type
Article
Date
2004
Author
N K Kostriukova
V A Karpin
N V Kuz'mina
A I Vialkov
Source
Probl Tuberk Bolezn Legk. 2004;(12):44-7
Date
2004
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Aged
Child
Child, Preschool
Comparative Study
English Abstract
Female
Gamma Rays
Geology
Humans
Industry
Infant
Infant, Newborn
Magnetics
Male
Middle Aged
Radon
Risk factors
Sex Factors
Siberia - epidemiology
Tuberculosis, Pulmonary - epidemiology
Urban Population
Abstract
The purpose of the present study was to examine the association of the incidence and severity of primary pulmonary tuberculosis with the anomalies of physical factors (geomagnetic field, gamma-radiation, radon emanation) above the local earth's crustal fractures (LECF) on the territory of Surgut. Analyzing the findings indicated the significant prevalence of both the rates of total primary morbidity of pulmonary tuberculosis and its exudative forms and the predominance of bacterial isolating patients among the residents in the area of LECF versus the continuum. Antituberculosis therapeutic-and-prophylactic measures should be planned, by taking into account the regional features of the state of anomalous physical fields.
PubMed ID
15719667 View in PubMed
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Association of radiation-induced genes with noncancer chronic diseases in Mayak workers occupationally exposed to prolonged radiation.

https://arctichealth.org/en/permalink/ahliterature263140
Source
Radiat Res. 2015 Mar;183(3):249-61
Publication Type
Article
Date
Mar-2015
Author
Michael Abend
Tamara Azizova
Kerstin Müller
Harald Dörr
Sven Doucha-Senf
Helmut Kreppel
Galina Rusinova
Irina Glazkova
Natalia Vyazovskaya
Kristian Unger
Herbert Braselmann
Viktor Meineke
Source
Radiat Res. 2015 Mar;183(3):249-61
Date
Mar-2015
Language
English
Publication Type
Article
Keywords
Chronic Disease - epidemiology
Dose-Response Relationship, Radiation
Female
Gamma Rays
Gene Expression Regulation - radiation effects
Humans
Male
MicroRNAs - biosynthesis
Nuclear Power Plants
Occupational Exposure
RNA, Messenger - biosynthesis
Radiation Injuries
Russia
Abstract
We examined the association of gene expression with noncancer chronic disease outcomes in Mayak nuclear weapons plant workers who were exposed to radiation due to their occupation. We conducted a cross-sectional study with selection based on radiation exposure status of Mayak plant workers living in Ozyorsk who were alive in 2011 and either exposed to: combined incorporated Plutonium-239 ((239)Pu) and external gamma-ray exposure (n = 82); external gamma-ray exposure alone (n = 18); or were unexposed (n = 50) of Ozyorsk residents who provided community-based professional support for plant personnel and who were alive in 2011. Peripheral blood was taken and RNA was isolated and then converted into cDNA and stored at -20°C. In a previous analysis we screened the whole genome for radiation-associated candidate genes, and validated 15 mRNAs and 15 microRNAs using qRT-PCR. In the current analysis we examined the association of these genes with 15 different chronic diseases on 92 samples (47 males, 45 females). We examined the radiation-to-gene and gene-to-disease associations in statistical models stratified by gender and separately for each disease and exposure. We modeled radiation exposure as gamma or (239)Pu on both the continuous and categorical scales. Unconditional logistic regression was used to calculate odds ratios (OR), 95% confidence intervals (CI), and the concordance for genes that were significantly associated with radiation exposure and a specific disease outcome were identified. Altogether 12 mRNAs and 9 microRNAs appeared to be significantly associated with 6 diseases, including thyroid diseases (3 genes, OR: 1.2-5.1, concordance: 71-78%), atherosclerotic diseases (4 genes, OR: 2.5-10, concordance: 70-75%), kidney diseases (6 genes, OR: 1.3-8.6, concordance: 69-85%), cholelithiasis (3 genes, OR: 0.2-0.3, concordance: 74-75%), benign tumors [1 gene (AGAP4), OR: 3.7, concordance: 81%] and chronic radiation syndrome (4 genes, OR: 2.5-4.3, concordance: 70-99%). Further associations were found for systolic blood pressure (6 genes, OR: 3.7-10.6, concordance: 81-88%) and body mass index [1 gene (miR-484), OR: 3.7, concordance: 81%]. All associations were gender and exposure dependent. These findings suggest that gene expression changes observed after occupational prolonged radiation exposures may increase the risk for certain noncancer chronic diseases.
PubMed ID
25706777 View in PubMed
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142 records – page 1 of 15.