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23 records – page 1 of 3.

Altered erythrocyte n-3 fatty acids in Mediterranean patients with coronary artery disease.

https://arctichealth.org/en/permalink/ahliterature5155
Source
Int J Cardiol. 2001 Mar;78(1):27-32
Publication Type
Article
Date
Mar-2001
Author
F. Paganelli
J M Maixent
M J Duran
R. Parhizgar
G. Pieroni
S. Sennoune
Author Affiliation
Division of Cardiology, Hôpital Nord, School of Medicine, Marseille, France.
Source
Int J Cardiol. 2001 Mar;78(1):27-32
Date
Mar-2001
Language
English
Publication Type
Article
Keywords
Adult
Aged
Coronary Disease - blood
Erythrocyte Membrane - chemistry
Fatty Acids - analysis
Fatty Acids, Omega-3 - analysis
Female
France
Humans
Male
Middle Aged
Research Support, Non-U.S. Gov't
Abstract
A low frequency of ischaemic heart diseases in Eskimos has been related to polyunsaturated fatty acids. We therefore studied fatty acid patterns associated with coronary artery disease (CAD) for a possible relationship between fatty acid profile and CAD diagnosis in Mediterranean patients. The gas chromatography method was used to analyze the membranes of patients' erythrocytes. The patients without coronary stenosis were used as controls. Patients with CAD showed increased percentages of saturated fatty acids (35.8 vs. 34.2%, P
PubMed ID
11259810 View in PubMed
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Atopic sensitization during the first year of life in relation to long chain polyunsaturated fatty acid levels in human milk.

https://arctichealth.org/en/permalink/ahliterature33674
Source
Pediatr Res. 1998 Oct;44(4):478-84
Publication Type
Article
Date
Oct-1998
Author
K. Duchén
G. Yu
B. Björkstén
Author Affiliation
Department of Paediatrics, Linköping University, Sweden.
Source
Pediatr Res. 1998 Oct;44(4):478-84
Date
Oct-1998
Language
English
Publication Type
Article
Keywords
Arachidonic Acids - analysis
Breast Feeding
Comparative Study
Fatty Acids, Omega-3 - analysis
Fatty Acids, Omega-6
Fatty Acids, Unsaturated - analysis
Female
Follow-Up Studies
Humans
Hypersensitivity, Immediate - epidemiology - etiology
Infant
Infant, Newborn
Longitudinal Studies
Milk, human - chemistry
Mothers
Prospective Studies
Research Support, Non-U.S. Gov't
Risk factors
Skin Tests
Sweden
Time Factors
Abstract
The levels of the long chain polyunsaturated n-6 and n-3 fatty acids (PUFA) were studied in colostrum and mature milk of 29 atopic and 29 nonatopic mothers and related to sensitization in their babies during the first 12 mo of life. The levels of alpha-linolenic acid (LNA) were lower (0.96 versus 1.23 weight percentage, p
PubMed ID
9773834 View in PubMed
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Characterization of protein, lipid and mineral contents in common Norwegian seaweeds and evaluation of their potential as food and feed.

https://arctichealth.org/en/permalink/ahliterature267633
Source
J Sci Food Agric. 2014 Dec;94(15):3281-90
Publication Type
Article
Date
Dec-2014
Author
Hanne K Maehre
Marian K Malde
Karl-Erik Eilertsen
Edel O Elvevoll
Source
J Sci Food Agric. 2014 Dec;94(15):3281-90
Date
Dec-2014
Language
English
Publication Type
Article
Keywords
Amino Acids - analysis
Animal Feed
Animals
Arsenic - analysis
Cereals
Fatty Acids - analysis
Fatty Acids, Omega-3 - analysis
Food
Fucus - chemistry
Humans
Iodine - analysis
Laminaria - chemistry
Lipids - analysis
Metals, Heavy - analysis
Minerals - analysis
Norway
Proteins - analysis
Rhodophyta - chemistry
Seaweed - chemistry
Ulva - chemistry
Abstract
The objectives of this study were to examine protein and amino acid composition, lipid and fatty acid composition, along with a range of essential minerals in common Norwegian seaweed species representing the red (Palmaria palmata and Vertebrata lanosa), green (Cladophora rupestris, Enteromorpha intestinalis and Ulva lactuca) and brown (Alaria esculenta, Laminaria digitata, Laminaria hyperborea, Fucus vesiculosus and Pelvetia canaliculata) classes and assess their potential as alternatives to cereals in food and feed. As macroalgae accumulate heavy metals, arsenic, cadmium and mercury were also analyzed.
Proteins ranged from 34 to 123?g?kg(-1) dry weight (DW) and the essential amino acid levels may cover both human and salmonid requirements. Lipids were low (6-58?g?kg(-1) DW), but the red algae had high relative content of long-chained omega-3 fatty acids (32-34 % of the fatty acids). Iodine contents were particularly high in the Laminaria species. Of the heavy metals only arsenic levels may be of concern.
In total, the red alga P. palmata was regarded as the best alternative to cereals in food and feed. For several of the other species, single-component extraction for the ingredients market may be better than using the whole product.
PubMed ID
24700148 View in PubMed
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Contents of total fat, fatty acids, starch, sugars and dietary fibre in Swedish market basket diets.

https://arctichealth.org/en/permalink/ahliterature265131
Source
Br J Nutr. 2015 May 14;113(9):1453-65
Publication Type
Article
Date
May-14-2015
Author
W. Becker
A. Eriksson
M. Haglund
S. Wretling
Source
Br J Nutr. 2015 May 14;113(9):1453-65
Date
May-14-2015
Language
English
Publication Type
Article
Keywords
Diet
Dietary Carbohydrates - analysis
Dietary Fats - analysis
Dietary Fiber - analysis
Dietary Sucrose - analysis
Fatty Acids - analysis
Fatty Acids, Omega-3 - analysis
Fatty Acids, Omega-6 - analysis
Food
Fructose - analysis
Glucose - analysis
Humans
Nutrition Policy
Starch - analysis
Sweden
Trans Fatty Acids - analysis
Abstract
The typical dietary supply of total fat, fatty acids, starch, sugars, polyols and dietary fibre in Sweden was assessed from analyses of market baskets (MB) purchased in 2005 and 2010. MB were based on food balance sheets, with each basket comprising about 130 foods, which represented more than 90% of annual dietary supply. Foods were divided into ten to twelve categories. In 2010, total fat contributed 34% of energy (E%), SFA 14.3 E%, MUFA 12.8 E%, PUFA 4.6 E%, n-6 fatty acids 3.6 E%, n-3 fatty acids 1.0 E% and trans-fatty acids (TFA) 0.5 E%. Glycaemic carbohydrates contributed 47 E%, monosaccharides 9 E%, sucrose 11 E%, disaccharides 15 E% and total sugars 24 E%. Added sugars contributed about 15 E%. Dietary fibre content was about 1.7 g/MJ in the 2010 MB. Compared with the 2005 MB, the dietary supply of TFA and dietary fibre was lower, otherwise differences were small. The present MB survey shows that the content of SFA and added sugars was higher than the current Nordic Nutrition Recommendations, while the content of PUFA and especially dietary fibre was lower. TFA levels decreased and dietary supply was well below the recommendations of the WHO. These results emphasise a focus on quality and food sources of fat and carbohydrates, limiting foods rich in SFA and added sugars and replacing them with foods rich in dietary fibre and cis-unsaturated fatty acids.
Notes
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PubMed ID
25989998 View in PubMed
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A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: the Sysdimet study.

https://arctichealth.org/en/permalink/ahliterature131856
Source
Diabetologia. 2011 Nov;54(11):2755-67
Publication Type
Article
Date
Nov-2011
Author
V D F de Mello
U. Schwab
M. Kolehmainen
W. Koenig
M. Siloaho
K. Poutanen
H. Mykkänen
M. Uusitupa
Author Affiliation
Department of Clinical Nutrition/Food and Health Research Centre, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, FIN-70211 Kuopio, Finland. Vanessa.Laaksonen@uef.fi
Source
Diabetologia. 2011 Nov;54(11):2755-67
Date
Nov-2011
Language
English
Publication Type
Article
Keywords
Aged
Animals
Biological Markers - blood
Body mass index
C-Reactive Protein - analysis
Cereals - chemistry
Dietary Fiber - administration & dosage - analysis
E-Selectin - blood
Endothelium, Vascular - immunology - physiopathology
Fatty Acids, Omega-3 - analysis - therapeutic use
Female
Finland
Fishes
Fruit
Glucose Metabolism Disorders - blood - diet therapy - immunology - physiopathology
Humans
Male
Metabolic Syndrome X - blood - diet therapy - immunology - physiopathology
Middle Aged
Seafood - analysis
Vaccinium myrtillus
Abstract
Low-grade inflammation and endothelial dysfunction may play a role in the pathogenesis of type 2 diabetes and cardiovascular disease. We evaluated whether a diet high in fatty fish, bilberries and wholegrain products (Healthy Diet) improves biomarkers reflecting inflammation and endothelial dysfunction in individuals with impaired glucose metabolism.
We recruited individuals with impaired glucose metabolism and features of the metabolic syndrome into a 12 week, parallel design, dietary intervention trial conducted at the Department of Clinical Nutrition, University of Eastern Finland (Kuopio, Finland). Randomisation was performed by matching according to sex and medians of age, BMI and fasting plasma glucose of the study population at screening. The primary endpoint in the present study was the change in plasma inflammatory markers and the measurements were performed blinded to group assignment. High-sensitivity (hs) C-reactive protein (CRP) and E-selectin responses were also analysed separately in participants not using statins (n?=?76).
Altogether, 131 individuals were assigned to either the Healthy Diet (n?=?44), a whole-grain-enriched diet (WGED) (n?=?42) or a control (n?=?45) diet, and 104 participants (mean?±?SD: age 59?±?7 years; BMI 31.1?±?3.5 kg/m(2)) who had completed the study, were analysed (Healthy Diet n?=?36, WGED n?=?34 and control diet n?=?34). Plasma E-selectin decreased only in the Healthy Diet group. This occurred in all group participants (p?
PubMed ID
21870174 View in PubMed
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Fatty acid composition in hybrid pigs as based on local fatty Lithuanian breed and wild boar.

https://arctichealth.org/en/permalink/ahliterature118721
Source
Food Sci Technol Int. 2012 Dec;18(6):515-22
Publication Type
Article
Date
Dec-2012
Author
V. Razmaite
G J Švirmickas
Author Affiliation
Institute of Animal Science, Lithuanian University of Health Sciences, Baisogala, Lithuania. razmusv@one.it
Source
Food Sci Technol Int. 2012 Dec;18(6):515-22
Date
Dec-2012
Language
English
Publication Type
Article
Keywords
Animals
Animals, Wild
Crosses, Genetic
Dietary Fats - analysis
Energy intake
Fatty Acids - metabolism
Fatty Acids, Monounsaturated - analysis - metabolism
Fatty Acids, Omega-3 - analysis - metabolism
Fatty Acids, Omega-6 - analysis - metabolism
Female
Food Quality
Humans
Lithuania
Male
Meat - analysis
Muscle, Skeletal - growth & development - metabolism
Sex Characteristics
Subcutaneous Tissue - growth & development - metabolism
Sus scrofa - growth & development - metabolism
Abstract
The study was designed to investigate the fatty acid composition in longissimus dorsi (LD) and semimembranosus muscles (SM) and subcutaneous tissue of hybrid (1/4 Lithuanian indigenous wattle, 1/4 wild boar and 1/2 Yorkshire or 1/2 Landrace) pigs. The SM showed a tendency to have lower contents of monounsaturated fatty acids (MUFA) and higher contents of polyunsaturated fatty acids (PUFA) than the LD muscle. No statistically significant differences were observed between the muscles in lipid quality indices, i.e., atherogenic (AI) and thrombogenix (TI) indices and the ratio of hypocholesterolemic and hypercholesterolemic fatty acids (h/H). In the SM, the content of PUFA from Yorkshire-sired hybrids was relatively 47.8% higher, including C18:2n-6, C20:4n-6 and DPA (C22:5n-3) that were higher, respectively, by 44.3%, 86.6% and 51.6% in comparison with those from Landrace-sired hybrids. The gilts had a lower content of MUFA, including C18:1 and C20:1n-9 fatty acids in the LD muscle and tended to have a higher content of PUFA in the SM compared to the barrows. Neither the terminal breed in crossing, nor the gender had any significant effects on the proportions of total saturated, MUFA and PUFA in the subcutaneous tissue.
PubMed ID
23175780 View in PubMed
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Fatty acid composition of human milk in atopic Danish mothers.

https://arctichealth.org/en/permalink/ahliterature81529
Source
Am J Clin Nutr. 2006 Jul;84(1):190-6
Publication Type
Article
Date
Jul-2006
Author
Lauritzen Lotte
Halkjaer Liselotte Brydensholt
Mikkelsen Tina B
Olsen Sjurdur F
Michaelsen Kim F
Loland Lotte
Bisgaard Hans
Author Affiliation
Department of Human Nutrition, Center for Advanced Food Studies, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark. ll@kvl.dk
Source
Am J Clin Nutr. 2006 Jul;84(1):190-6
Date
Jul-2006
Language
English
Publication Type
Article
Keywords
Adult
Asthma - metabolism
Cohort Studies
Denmark
Dermatitis, Atopic - metabolism
Diet
Fatty Acids, Omega-3 - analysis
Fatty Acids, Omega-6 - analysis
Fatty Acids, Unsaturated - analysis - metabolism
Female
Humans
Infant, Newborn
Lactation - metabolism
Milk, human - chemistry
Prospective Studies
Questionnaires
Abstract
BACKGROUND: Atopic dermatitis has been related to a disturbed metabolism of polyunsaturated fatty acids (PUFAs). OBJECTIVE: We tested whether the PUFA composition of breast milk differs significantly between mothers with atopic dermatitis, mothers with other types of atopy, and nonatopic mothers. We also investigated whether differences in diet can explain possible observed differences. DESIGN: Mothers with current or previous asthma (n = 396) were divided into 3 groups according to history of atopic dermatitis and allergic rhinitis. Breast-milk samples were collected from 314 women approximately 3 wk after delivery. The habitual diet of the women was assessed with food-frequency questionnaires in the 25th week of gestation (n = 207). Breast-milk samples and simultaneous dietary data from 14 nonatopic mothers were used for comparison. RESULTS: Compared with the milk of nonatopic mothers, that of atopic mothers had significantly higher concentrations of 22:5n-6 and lower concentrations of 20:5n-3; moreover, 20:4n-6/20:5n-3, 22:5n-6/22:6n-3, and long-chain n-3 PUFA/18:3n-3 were shifted toward n-6 PUFA and 18:3n-3 in nonatopic and atopic mothers, respectively. No differences in breast-milk PUFA composition were evident between the subject groups. The diets of the groups differed only slightly with respect to protein intake. However, the PUFA composition of the breast milk was associated with diet and time of milk sampling, and the above difference in milk PUFAs disappeared when those factors were taken into account. CONCLUSION: Our data do not support the possibility that the fatty acid composition of breast milk is affected by atopic dermatitis or atopy in general, because most differences in breast-milk PUFA composition appear to be explained by the diet.
PubMed ID
16825695 View in PubMed
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Flaxseed on cardiovascular disease markers in healthy menopausal women: a randomized, double-blind, placebo-controlled trial.

https://arctichealth.org/en/permalink/ahliterature160488
Source
Nutrition. 2008 Jan;24(1):23-30
Publication Type
Article
Date
Jan-2008
Author
Sylvie Dodin
Stephen C Cunnane
Benoît Mâsse
André Lemay
Hélène Jacques
Geneviève Asselin
Jennifer Tremblay-Mercier
Isabelle Marc
Benoît Lamarche
France Légaré
Jean-Claude Forest
Author Affiliation
Department of Obstetrics and Gynecology, Research Center, St-François d'Assise Hospital (CHUQ), Quebec, Quebec, Canada. sylvie.dodin@og.ulaval.ca
Source
Nutrition. 2008 Jan;24(1):23-30
Date
Jan-2008
Language
English
Publication Type
Article
Keywords
Aged
Apolipoprotein A-I - blood - metabolism
Apolipoproteins B - blood - metabolism
Biological Markers - blood
Blood Glucose - metabolism
C-Reactive Protein - metabolism
Cardiovascular Diseases - blood
Dietary Supplements
Double-Blind Method
Fatty Acids, Omega-3 - analysis - blood
Female
Fibrinogen - metabolism
Flax
Humans
Insulin - blood
Lipoproteins, LDL - blood
Menopause
Middle Aged
Particle Size
Placebos
Quebec
Triticum
Abstract
Due to its high content of lignans, alpha-linolenic acid and fiber, flaxseed may reduce cardiovascular disease risk in humans. The present study evaluated the effect of flaxseed on markers of cardiovascular disease risk in healthy menopausal women.
One hundred ninety-nine women were randomly assigned to consume 40 g daily of flaxseed or wheat germ placebo for 12 mo. Fatty acids, apolipoproteins A-1 and B, lipoprotein(a), low-density lipoprotein particle size, fibrinogen, C-reactive protein, insulin, and glucose were measured at baseline and at 12 mo.
In total 179 women were available for the intention-to-treat analysis. Flaxseed increased plasma alpha-linolenic (P
PubMed ID
17981439 View in PubMed
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High-resolution ┬╣H magic angle spinning NMR spectroscopy of intact Arctic char (Salvelinus Alpinus) muscle. Quantitative analysis of n-3 fatty acids, EPA and DHA.

https://arctichealth.org/en/permalink/ahliterature259268
Source
J Agric Food Chem. 2010 Oct 27;58(20):10799-803
Publication Type
Article
Date
Oct-27-2010
Author
Gustav Nestor
Johan Bankefors
Christian Schlechtriem
Eva Brännäs
Jana Pickova
Corine Sandström
Source
J Agric Food Chem. 2010 Oct 27;58(20):10799-803
Date
Oct-27-2010
Language
English
Publication Type
Article
Keywords
Animals
Docosahexaenoic Acids - analysis - metabolism
Eicosapentaenoic Acid - analysis - metabolism
Fatty Acids, Omega-3 - analysis - metabolism
Fish Products - analysis
Magnetic Resonance Spectroscopy - instrumentation - methods
Muscle, Skeletal - chemistry - metabolism
Trout - metabolism
Abstract
The lipid and small metabolite profiles from intact muscles of Arctic char were investigated using (1)H high-resolution magic angle spinning ((1)H HR-MAS) NMR spectroscopy. Not only the total n-3 fatty acid content but also the eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) contents of the muscle were obtained from the (1)H HR-MAS NMR spectra without pretreatment of the tissue or lipophilic extraction. A number of small metabolites could also be observed, where creatine/phosphocreatine, anserine and taurine were the most abundant. Thus, the use of (1)H HR-MAS NMR led to simplified analysis techniques that can give direct information on the nutritional value of the fish.
PubMed ID
20873863 View in PubMed
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Impairment of cellular immunity in west Greenland sledge dogs (Canis familiaris) dietary exposed to polluted minke whale (Balaenoptera acutorostrata) blubber.

https://arctichealth.org/en/permalink/ahliterature95741
Source
Environ Sci Technol. 2006 Mar 15;40(6):2056-62
Publication Type
Article
Date
Mar-15-2006
Author
Sonne Christian
Dietz Rune
Larsen Hans J S
Loft Klaus Earl
Kirkegaard Maja
Letcher Robert J
Shahmiri Soheila
Móller Per
Author Affiliation
Department of Arctic Environment, National Environmental Research Institute, DK-4000 Roskilde, Denmark. csh@dmu.dk
Source
Environ Sci Technol. 2006 Mar 15;40(6):2056-62
Date
Mar-15-2006
Language
English
Publication Type
Article
Keywords
Animals
Arctic Regions
Climate
Dogs
Environmental Pollutants - toxicity
Fatty Acids, Omega-3 - analysis - toxicity
Food Contamination
Greenland
Hydrocarbons, Halogenated - analysis - toxicity
Immunity, Cellular - drug effects
Mercury - analysis - toxicity
Minke Whale
Ursidae
Abstract
Minke whale (Balaenoptera acutorostrata) blubber is rich in organohalogen contaminants, mercury, and n-3 fatty acids. In the present study we show that a daily intake of 50-200 g of minke whale blubber causes an impairment of the nonspecific and specific cellular immune system in the West Greenland sledge dog (Canis familiaris). Immune reactions were measured by mitogen (PHA, Con A) and antigen (KLH) intradermal testing, and as the study used exposure levels similar to those of Inuits and polar bears (Ursus maritimus), it is reasonable to infer that Inuits and polar bears suffer from similar decreased resistance to diseases. It is speculated that food sources are depleted by thinning sea ice due to climate change and that more research should assess the forecasted rise in additive immunopathy effects in polar bears. Additionally, our study suggests that the fatty acid composition may be of importance when investigating combined immunotoxic effects of contaminated food resources in future Inuit and polar bear studies.
PubMed ID
16570636 View in PubMed
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23 records – page 1 of 3.