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251 records – page 1 of 26.

1. Fatal acute hepatitis in infectious mononucleosis in a forensic setting: a case report.

https://arctichealth.org/en/permalink/ahliterature173239
Source
Med Sci Law. 2005 Jul;45(3):261-4
Publication Type
Article
Date
Jul-2005
Author
Anny Sauvageau
Stéphanie Racette
Author Affiliation
Laboratoire de Sciences Judiciaires et de Médecine Légale, Edifice Wilfrid-Derome 1701, Parthenais Street, 12th floor, Montreal, Quebec, Canada H2K 3S7. a.sauvageau@msp.gouv.qc.ca
Source
Med Sci Law. 2005 Jul;45(3):261-4
Date
Jul-2005
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Fatal Outcome
Female
Forensic Medicine
Hepatitis - complications - physiopathology
Humans
Infectious Mononucleosis - complications
Quebec
Abstract
Mononucleosis is generally considered a benign, self-limited disease. However, though uncommon, fatal complications are sometimes encountered. Deaths from liver failure, splenic rupture, respiratory obstruction, neurological complications, secondary infections and bleeding complications have been described. In the forensic setting, there are a few reports of sudden and unexplained deaths from splenic rupture and upper airway obstruction. We report here the first case of sudden and unexplained death from acute hepatitis in infectious mononucleosis presenting as a suspicious death.
PubMed ID
16117288 View in PubMed
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2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: identification and measurement of TCDD metabolites.

https://arctichealth.org/en/permalink/ahliterature95137
Source
Lancet. 2009 Oct 3;374(9696):1179-85
Publication Type
Article
Date
Oct-3-2009
Author
Sorg O.
Zennegg M.
Schmid P.
Fedosyuk R.
Valikhnovskyi R.
Gaide O.
Kniazevych V.
Saurat J-H
Author Affiliation
Dermato-Toxicology, Swiss Centre for Applied Human Toxicology, and Department of Dermatology, University Hospital, Geneva, Switzerland.
Source
Lancet. 2009 Oct 3;374(9696):1179-85
Date
Oct-3-2009
Language
English
Publication Type
Article
Keywords
Adipose Tissue - chemistry
Biopsy
Drug Residues - analysis - metabolism
Fatal Outcome
Feces - chemistry
Forensic Medicine - methods
Half-Life
Homicide
Humans
Male
Middle Aged
Politics
Substance Abuse Detection - methods
Sweat - chemistry
Tetrachlorodibenzodioxin - analysis - chemistry - metabolism - poisoning
Time Factors
Ukraine
Abstract
BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has a long half-life of 5-10 years in human beings as a result of its high lipophilicity, and little or no metabolism. We monitored TCDD, its form, distribution, and elimination in Victor Yushchenko after he presented with severe poisoning. METHODS: In late December, 2004, a patient presented with TCDD poisoning; the levels in his blood serum (108000 pg/g lipid weight) were more than 50 000-fold greater than those in the general population. We identified TCDD and its metabolites, and monitored their levels for 3 years using gas chromatography and high-resolution mass spectrometry in samples of blood serum, adipose tissue, faeces, skin, urine, and sweat, after they were extracted and cleaned with different organic solvents. FINDINGS: The amount of unmodified TCDD in the samples that were analysed accounted for about 60% of TCDD eliminated from the body during the same period. Two TCDD metabolites-2,3,7-trichloro-8-hydroxydibenzo-p-dioxin and 1,3,7,8-tetrachloro-2-hydroxydibenzo-p-dioxin-were identified in the faeces, blood serum, and urine. The faeces contained the highest concentration of TCDD metabolites, and were the main route of elimination. Altogether, the different routes of elimination of TCDD and its metabolites accounted for 98% of the loss of the toxin from the body. The half-life of TCDD in our patient was 15.4 months. INTERPRETATION: This case of poisoning with TCDD suggests that the design of methods for routine assessment of TCDD metabolites in human beings should be a main aim of TCDD research in the metabolomic era. FUNDING: University of Geneva Dermatology Fund, and Swiss Centre for Applied Human Toxicology.
Notes
Comment In: Lancet. 2009 Oct 3;374(9696):1131-219660808
PubMed ID
19660807 View in PubMed
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A2 (N-benzylpiperazine) a new drug of abuse in Sweden.

https://arctichealth.org/en/permalink/ahliterature9523
Source
J Anal Toxicol. 2004 Jan-Feb;28(1):67-70
Publication Type
Article
Author
Maria Wikström
Per Holmgren
Johan Ahlner
Author Affiliation
National Board of Forensic Medicine, Department of Forensic Chemistry, University Hospital, Linköping, Sweden. maria.wikstrom@rmv.se
Source
J Anal Toxicol. 2004 Jan-Feb;28(1):67-70
Language
English
Publication Type
Article
Keywords
Adult
Fatal Outcome
Forensic Medicine
Humans
Male
Piperazines - analysis
Substance Abuse Detection - methods
Sweden
Abstract
N-Benzylpiperazine was tested in the beginning of the 1970s as a possible antidepressant drug. However, in both animal and human studies, it was shown to possess amphetamine-like properties, and any further studies were stopped. In a forensic autopsy case in 1999, we found a substance so far unknown to us in the chromatogram of our method used for amphetamines. We could swiftly identify this compound as N-benzylpiperazine because of information given to us by a newly formed network comprising, among others, customs and the police. Since then, we have found N-benzylpiperazine in several cases, among them 11 cases from a number of prisons.
PubMed ID
14987428 View in PubMed
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Source
Dan Medicinhist Arbog. 2015;43:101-8
Publication Type
Article
Date
2015
Author
Sven Erik Hansen
Source
Dan Medicinhist Arbog. 2015;43:101-8
Date
2015
Language
Danish
Publication Type
Article
Keywords
Denmark
Fatal Outcome
Female
Fetal Death - etiology
History, 19th Century
Humans
Medical Illustration - history
Obstetrics - history
Osteomyelitis - complications - history - pathology
Parturition
Periodicals as Topic
Pregnancy
Abstract
A birth with fatal outcome for both the mother and the foetus was reported in the Danish medical journal, Bibliothek for Læger in 1868. Here, the article with its two illustrations is summarised because of the vivid description of the course together with the therapeutic considerations expressed by the obstetrician. Due to an earlier osteomyelitis the pregnant woman's spine was deformed and her pelvis was narrowed. The birth came to a standstill, and it became necessary to reduce the circumference of the foetus' cranium by perforation, after which the dead foetus could be delivered. The woman died of infection some days later. Afterwards her deformed lumbar spine and pelvis was removed, preserved and depicted in two lithographs. The preserved pelvis is still extant in the Saxtorphian obstetric collection in Medical Museion, Copenhagen.
PubMed ID
27086448 View in PubMed
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[A case of non-Hodgkin T-cell lymphoma with predominantly cutaneous manifestations]

https://arctichealth.org/en/permalink/ahliterature23132
Source
Clin Ter. 1995 Aug-Sep;146(8-9):537-42
Publication Type
Article
Author
U. di Tondo
M. Pergolini
L. Coppotelli
P. Visca
B. Monarca
M. Paradiso
S. Basili
M. Leonardo
E. Paris
C. Cordova
Author Affiliation
Università degli Studi di Roma La Sapienza, Istituto di Terapia Medica.
Source
Clin Ter. 1995 Aug-Sep;146(8-9):537-42
Language
Italian
Publication Type
Article
Keywords
Accidents, Radiation
English Abstract
Ethiopia - ethnology
Fatal Outcome
Humans
Lymphoma, Non-Hodgkin - etiology - pathology
Lymphoma, T-Cell, Cutaneous - etiology - pathology
Male
Middle Aged
Neoplasms, Radiation-Induced
Power Plants
Ukraine
Abstract
There is a wealth of experiences concerning cancer and leukemia induced in human populations by radiation. The contribution of the nuclear industry to the radiation exposure of the general population is small, but there is the risk of catastrophic accidents causing a large number of deaths. The authors describe the case of a 48 year old black man accidentally exposed to the effects of radiations during the nuclear disaster of Chernobyl in 1986. The patient showed, many years later, a predominantly cutaneous high-grade T cell lymphoma, which was refractory to traditional treatments but sensitive to high doses of a recombinant interferon. Unluckily the patient died, six months later, because of autoinfection overwhelming. The goal of the authors is again to ask to reflect on the risk of the use of nuclear power and to debate the possible choice of the still experimental treatments.
PubMed ID
8536436 View in PubMed
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[A case of the tick (Ixodidae) hiperinvasion of the tundra vole in magadan environs].

https://arctichealth.org/en/permalink/ahliterature289887
Source
Parazitologiia. 2017 Jan-Feb; 51(1):45-50
Publication Type
Case Reports
Journal Article
Author
N E Dokuchaev
Source
Parazitologiia. 2017 Jan-Feb; 51(1):45-50
Language
Russian
Publication Type
Case Reports
Journal Article
Keywords
Animals
Arvicolinae - parasitology
Fatal Outcome
Ixodes - pathogenicity - physiology
Male
Siberia
Tick Infestations - parasitology - pathology
Tundra
Abstract
A case of tundra vole death as a result its hyperinvasion by ticks Ixodes angustus on the northern periphery of the Asiatic range of the parasite is given.
PubMed ID
29401575 View in PubMed
Less detail
Source
Dan Medicinhist Arbog. 2015;43:31-6
Publication Type
Article
Date
2015
Author
Sven Erik Hansen
Source
Dan Medicinhist Arbog. 2015;43:31-6
Date
2015
Language
Danish
Publication Type
Article
Keywords
Barbados
Denmark
Fatal Outcome
History, 19th Century
Humans
Military Personnel
Yellow Fever - history - parasitology - pathology
Abstract
A young Danish sailor died from yellow fever in Barbados in 1887. The Shipmaster's letter to the family with a description of the course of the disease, which has been preserved, is presented here together with a photo of the sailor and a painting of the Danish sailing-ship.
PubMed ID
27086445 View in PubMed
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Acting on a living will: a physician's dilemma.

https://arctichealth.org/en/permalink/ahliterature211004
Source
CMAJ. 1996 Oct 1;155(7):893-5
Publication Type
Article
Date
Oct-1-1996
Author
M. Gordon
D. Levitt
Author Affiliation
Baycrest Centre for Geriatric Care, North York, Ont.
Source
CMAJ. 1996 Oct 1;155(7):893-5
Date
Oct-1-1996
Language
English
Publication Type
Article
Keywords
Aged
Canada
Chronic Disease
Combined Modality Therapy
Dissent and Disputes
Ethics Committees
Ethics Committees, Clinical
Ethics, Medical
Euthanasia, Passive - psychology
Fatal Outcome
Group Processes
Humans
Living Wills - psychology
Male
Moral Obligations
Personal Autonomy
Quadriplegia - complications - psychology - therapy
Social Values
Withholding Treatment
Abstract
The implementation of a living will can give rise to ethical dilemmas for the patient's family and the health care professionals involved. The case reported here raises questions about the right of patients to self-determination, the importance of quality-of-life considerations in treatment decisions and physicians' obligations with respect to the implementation of living wills. Physicians should ensure in advance that the instructions set out in a living will are unambiguous and should bring to the patient's attention any ethical difficulties that they foresee in carrying out those instructions.
Notes
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Cites: N Engl J Med. 1991 Mar 28;324(13):882-82000110
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Cites: Arch Intern Med. 1994 Jan 24;154(2):209-178285816
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Cites: CMAJ. 1994 Aug 1;151(3):285-98039081
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Cites: JAMA. 1989 Nov 3;262(17):2415-92795827
PubMed ID
8837536 View in PubMed
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251 records – page 1 of 26.