Skip header and navigation

2 records – page 1 of 1.

[Study of a factor released during myocardial ischemia reperfusion and its effects on myocardial, coronary and peripheral vessels]

https://arctichealth.org/en/permalink/ahliterature53761
Source
Fiziol Zh. 2002;48(1):3-8
Publication Type
Article
Date
2002
Author
V F Sahach
A V Dmytriieva
T V Shymans'ka
S M Nadtochii
Author Affiliation
A.A. Bogomoletz Institute of Physiology, National Academy of Science of Ukraine, Kiev.
Source
Fiziol Zh. 2002;48(1):3-8
Date
2002
Language
Ukrainian
Publication Type
Article
Keywords
Animals
Arrhythmia - physiopathology
Blood Circulation
Coronary Circulation
English Abstract
Exudates and Transudates - physiology
Guinea Pigs
Muscle Tonus
Myocardial Contraction
Myocardial Ischemia
Myocardial Reperfusion
Myocardial Reperfusion Injury
Myocardium - metabolism
Abstract
The effect of reoxygenated coronary effluent of an isolated guinea-pig heart on a sequentially perfused second heart, right auricle trabecula and arterial vessel rings was studied after 20 min ischaemia of the first heart. It has been shown that a factor released after myocardial ischemia/reperfusion stimulates arrhythmia, decreases myocardial contractility of the second heart and depresses tonical tension of the right auricle trabecula and arterial vessel rings. Storage of the coronary effluent up to 24 h did not modify its effects. These results suggest stable factor released from an isolated heart after ischaemia at reperfusion to exert humoral effect not only on a myocardial contractility and coronary circulation but on the peripheral vessels tonus.
PubMed ID
11928628 View in PubMed
Less detail