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Abstracts. Seventh annual meeting. The European Society for Paediatric Haematology and Immunology. Oslo, Norway, June 11-13, 1979.

https://arctichealth.org/en/permalink/ahliterature41315
Source
Pediatr Res. 1979 Aug;13(8):948-57
Publication Type
Conference/Meeting Material
Date
Aug-1979

Age-standardisation of relative survival ratios of cancer patients in a comparison between countries, genders and time periods.

https://arctichealth.org/en/permalink/ahliterature153684
Source
Eur J Cancer. 2009 Mar;45(4):642-7
Publication Type
Article
Date
Mar-2009
Author
Arun Pokhrel
Timo Hakulinen
Author Affiliation
Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Pieni Roobertinkatu 9, FI-00130 Helsinki, Finland. arun.pokhrel@cancer.fi
Source
Eur J Cancer. 2009 Mar;45(4):642-7
Date
Mar-2009
Language
English
Publication Type
Article
Keywords
Adult
Age Distribution
Aged
Aged, 80 and over
Child
Child, Preschool
Epidemiologic Methods
Europe - epidemiology
Female
Finland - epidemiology
Humans
Infant
Infant, Newborn
Male
Middle Aged
Neoplasms - mortality
Prognosis
Sex Distribution
United States - epidemiology
Young Adult
Abstract
A recent method of age-standardisation of relative survival ratios for cancer patients does not require calculation of age-specific relative survival ratios, as ratios of age-specific proportions between the standard population and study group at the beginning of the follow-up are used to substitute the original individual observations. This method, however, leads to direct age-standardisation with weights that are different for each patient group if the general population mortality patterns for the groups are different. This is the case in international comparisons, and in comparisons between genders and time periods. The magnitude of the bias caused by the differences in general population mortality is investigated for comparisons involving European countries and the USA. Patients in each country are assumed to have exactly the same age-specific relative survival ratios as those diagnosed in Finland in 1985-2004. An application of a properly functioning age-standardisation method should then give exactly equal age-standardised relative survival ratios for each country. However, the recent method shows substantial differences between countries, with highest relative survival for populations, where the general population mortality in the oldest ages is the highest. This source of error can thus be a serious limitation for the use of the method, and other methods that are available should then be employed.
PubMed ID
19081246 View in PubMed
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AIDS--dramatic surge in ex-Soviet Union, no respite worldwide, new data show.

https://arctichealth.org/en/permalink/ahliterature195656
Source
Bull World Health Organ. 2001;79(1):78
Publication Type
Article
Date
2001
Author
R. Dobson
Source
Bull World Health Organ. 2001;79(1):78
Date
2001
Language
English
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - epidemiology - mortality
Adolescent
Adult
Child
Child, Preschool
Europe, Eastern - epidemiology
Female
Humans
Infant
Infant, Newborn
Russia - epidemiology
Notes
Comment In: Bull World Health Organ. 2001;79(3):26911285679
PubMed ID
11217673 View in PubMed
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Allergic bronchopulmonary aspergillosis in cystic fibrosis. A European epidemiological study. Epidemiologic Registry of Cystic Fibrosis.

https://arctichealth.org/en/permalink/ahliterature32533
Source
Eur Respir J. 2000 Sep;16(3):464-71
Publication Type
Article
Date
Sep-2000
Author
G. Mastella
M. Rainisio
H K Harms
M E Hodson
C. Koch
J. Navarro
B. Strandvik
S G McKenzie
Author Affiliation
Dept of Pulmonary and Digestive Diseases of Developmental Age, Cystic Fibrosis Center, Verona, Italy.
Source
Eur Respir J. 2000 Sep;16(3):464-71
Date
Sep-2000
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aspergillosis, Allergic Bronchopulmonary - complications - epidemiology - physiopathology
Child
Child, Preschool
Cystic Fibrosis - complications
Europe - epidemiology
Female
Forced expiratory volume
Humans
Infant
Male
Middle Aged
Prevalence
Research Support, Non-U.S. Gov't
Abstract
Allergic bronchopulmonary aspergillosis (ABPA) is a disease resulting from a hypersensitivity response to Aspergillus fumigatus, although the pathogenesis of the disease is unknown and its prevalence in cystic fibrosis (CF) is still poorly defined. Data from the Epidemiologic Registry of Cystic Fibrosis (ERCF) on 12,447 CF patients gathered from 224 CF centres in nine European countries were analysed. The ERCF definition of ABPA diagnosis is a positive skin test and serum precipitins to A. fumigatus, together with serum immunoglobulin (Ig)E levels >1,000 U x mL(-1) and additional clinical or laboratory parameters. The overall prevalence of ABPA in the ERCF population was 7.8% (range: 2.1% in Sweden to 13.6% in Belgium). Prevalence was low or =20-12.9% in those with FEV1
Notes
Comment In: Eur Respir J. 2001 May;17(5):1052-311488309
PubMed ID
11028661 View in PubMed
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Allogeneic bone marrow transplantation for leukemia in Europe: regional differences. Report from the Leukemia Working party of the European Group for Bone Marrow Transplantation.

https://arctichealth.org/en/permalink/ahliterature25241
Source
Bone Marrow Transplant. 1990 Mar;5(3):159-65
Publication Type
Article
Date
Mar-1990
Author
A. Gratwohl
J. Hermans
A J Barrett
P. Ernst
F. Frassoni
G. Gahrton
A. Granena
H J Kolb
H G Prentice
J P Vernant
Author Affiliation
Department of Internal Medicine, University Hospital Basel, Switzerland.
Source
Bone Marrow Transplant. 1990 Mar;5(3):159-65
Date
Mar-1990
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Bone Marrow Transplantation - mortality - statistics & numerical data
Chi-Square Distribution
Child
Child, Preschool
Comparative Study
Europe - epidemiology
Female
Graft vs Host Disease - prevention & control
Humans
Infant
Leukemia, Lymphocytic, Acute - mortality - surgery
Leukemia, Myelocytic, Acute - mortality - surgery
Leukemia, Myeloid, Chronic - mortality - surgery
Male
Middle Aged
Multivariate Analysis
Proportional Hazards Models
Retrospective Studies
Survival Rate
Abstract
The results of 1904 allogeneic HLA identical sibling donor bone marrow transplants performed in 52 European centers between 1979 and 1986 and reported to the EBMT leukemia registry were analysed by geographical location of the transplant. Patients were grouped into six regions: United Kingdom, Nordic Group, Benelux, France, Central Europe and Southern Europe. There were significant differences between these regions with respect to patient population and outcome. The relative proportion of the three major disease categories, stage and subtype of the diseases, graft-versus-host disease prevention methods, donor recipient sex combinations, age of the patient, year of the transplant and the time intervals from diagnosis to transplant, from diagnosis to first complete remission for acute leukemia and the time from first complete remission to the transplant varied from region to region. The analysis of outcome parameters showed a significant difference in relapse incidence from region to region. This influence of region was confirmed in a multivariate analysis and was independent of the other factors known to affect outcome. Leukemia-free survival and transplant-related mortality were not different. The reasons for these differences could not be explained by the data in the registry. We conclude that regional factors must be considered when bone marrow transplant data are compared and we postulate that pretransplant factors probably affect outcome more than was previously realized.
PubMed ID
2331536 View in PubMed
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Alterations in T-lymphocyte subsets among Danish haemophiliacs: relation to source of factor VIII preparations and high dose factor VIII treatment.

https://arctichealth.org/en/permalink/ahliterature39856
Source
Scand J Haematol. 1984 May;32(5):544-51
Publication Type
Article
Date
May-1984
Author
J. Gerstoft
K. Bentsen
E. Scheibel
J. Dalsgård-Nielsen
J. Gormsen
E. Dickmeiss
Source
Scand J Haematol. 1984 May;32(5):544-51
Date
May-1984
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Alanine Transaminase - metabolism
Antibodies, Viral - analysis
Child
Child, Preschool
Cytomegalovirus - isolation & purification
Denmark
Drug Industry
Europe
Factor VIII - therapeutic use
Hemophilia A - immunology
Humans
Immunoglobulin G - analysis
Infant
Liver - enzymology
Middle Aged
T-Lymphocytes, Helper-Inducer - classification
T-Lymphocytes, Regulatory - classification
United States
Abstract
Screening of 43 healthy Danish haemophiliacs revealed a significantly lower helper/suppressor (H/S) ratio than in controls. 8 of the haemophiliacs had an H/S ratio less than or equal to 1.0. A significant negative correlation occurred between the total lifetime factor VIII treatment and the H/S ratio. However, high-dose factor VIII treatment given to patients with antibodies against factor VIII was not associated with immunological abnormalities. Children had a significantly higher H/S ratio than the adult haemophiliacs. Patients exclusively treated with Danish cryoprecipitate during the last year had a significantly higher H/S ratio than patients receiving preparations from other sources. This difference might, however, be explained by lower age and lower total lifetime dose in the group receiving Danish preparations. Haemophiliacs treated with American preparations did not differ immunologically from those treated with preparations of other origin. Total serum IgG was increased in 23% of the patients. This parameter was negatively correlated with the H/S ratio. The possible relation of the observed immunological alterations among otherwise healthy haemophiliacs to the acquired immune deficiency syndrome warrants further attention.
PubMed ID
6328639 View in PubMed
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American Academy of Pediatrics. Preventive health care for young children: Findings from a 10-country study and directions for United States policy.

https://arctichealth.org/en/permalink/ahliterature36720
Source
Pediatrics. 1992 May;89(5 Pt 2):981-98
Publication Type
Article
Date
May-1992
Author
B C Williams
C A Miller
Author Affiliation
Department of Maternal and Child Health, School of Public Health, University of North Carolina, Chapel Hill 27599-7400.
Source
Pediatrics. 1992 May;89(5 Pt 2):981-98
Date
May-1992
Language
English
Publication Type
Article
Keywords
Adolescent
Child
Child Advocacy
Child Health Services - economics - organization & administration - standards
Child Welfare
Child, Preschool
Comparative Study
Europe - epidemiology
Female
Great Britain - epidemiology
Health Policy
Health Services Accessibility - standards
Health Services Research
Humans
Immunization - standards
Infant
Infant mortality
Infant, Newborn
Male
Medical Record Linkage
Population Surveillance
Preventive Health Services - economics - organization & administration - standards
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Social Support
Social Welfare
United States - epidemiology
Wounds and Injuries - etiology - mortality
Abstract
Infant health and survival in the US compare unfavorably with other Western industrial democracies. Circumstances that contribute to favorable pregnancy outcomes in other countries include nearly complete participation of pregnant women in early prenatal care and linkage of care to extensive support benefits. The study reported here extends these earlier observations to preventive health services for children from infancy through adolescence and to the social benefit programs that support their families. This report looks at the condition of children in 10 European countries: Belgium, Denmark, France, the Federal Republic of Germany, Ireland, the Netherlands, Norway, Spain, Switzerland, and the United Kingdom. All of these countries have better infant survival rates than the US, and they all share elements of pluralism in their systems of health care.
Notes
Comment In: Pediatrics. 1992 Dec;90(6):1005-61437418
PubMed ID
1574377 View in PubMed
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Amoebiasis in a non-endemic country. Epidemiology, presenting symptoms and diagnostic methods.

https://arctichealth.org/en/permalink/ahliterature40267
Source
Scand J Infect Dis. 1983;15(2):207-14
Publication Type
Article
Date
1983
Author
P O Pehrson
Source
Scand J Infect Dis. 1983;15(2):207-14
Date
1983
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Amebiasis - epidemiology
Carrier State - diagnosis - epidemiology
Child
Child, Preschool
Diagnosis, Differential
Diarrhea - diagnosis - etiology
Entamoeba histolytica - isolation & purification
Entamoebiasis - diagnosis - epidemiology
Europe
Feces - parasitology
Female
Humans
Infant
Intestinal Diseases, Parasitic - diagnosis
Liver Abscess, Amebic - diagnosis
Male
Middle Aged
Parasite Egg Count - methods
Retrospective Studies
Sigmoidoscopy
Sweden
Travel
Abstract
392 patients with amoebiasis, diagnosed at Roslagstull Hospital, Stockholm during 10 yr, are reviewed. The disease is increasing in frequency, due both to increased travelling by Swedish citizens and immigration from non-European countries. The risk for an ordinary charter tourist is, however, rather low. Two-thirds of the patients were symptomatic and one-third were regarded as asymptomatic cyst carriers. The importance of repeated examination of stool samples and examinations using different techniques, especially direct microscopy of fresh faeces, is pointed out. The latter technique is in our laboratory shown to be as efficient in cases with no diarrhoea as in those with diarrhoea, with trophozoites demonstrated in the same frequency in both groups. Sigmoidoscopy with scrapings was seldom of diagnostic value.
PubMed ID
6308756 View in PubMed
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Analysis of Bordetella pertussis populations in European countries with different vaccination policies.

https://arctichealth.org/en/permalink/ahliterature29665
Source
J Clin Microbiol. 2005 Jun;43(6):2837-43
Publication Type
Article
Date
Jun-2005
Author
S C M van Amersfoorth
L M Schouls
H G J van der Heide
A. Advani
H O Hallander
K. Bondeson
C H W von König
M. Riffelmann
C. Vahrenholz
N. Guiso
V. Caro
E. Njamkepo
Q. He
J. Mertsola
F R Mooi
Author Affiliation
Laboratory for Vaccine Preventable Diseases. National Institute of Public Health and the Environment, Anthonie van Leeuwenhoeklaan 9, P.O. Box 1, 3720 BA Bilthoven, The Netherlands.
Source
J Clin Microbiol. 2005 Jun;43(6):2837-43
Date
Jun-2005
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Bacterial Proteins - genetics
Bordetella pertussis - classification - genetics - isolation & purification
Child
Child, Preschool
Europe
Fimbriae Proteins
Health Policy
Humans
Immunization Programs
Infant
Infant, Newborn
Minisatellite Repeats - genetics
Pertussis Vaccine - administration & dosage
Polymorphism, Genetic
Research Support, Non-U.S. Gov't
Serotyping
Vaccination
Virulence Factors - genetics
Whooping Cough - epidemiology - microbiology - prevention & control
Abstract
Despite the widespread use of pertussis vaccines during the last decades, pertussis has remained an endemic disease with frequent epidemic outbreaks. Currently two types of vaccines are used: whole-cell vaccines (WCVs) and recently developed acellular vaccines (ACVs). The long-term aim of our studies is to assess the effect of different vaccination policies on the population structure of Bordetella pertussis and ultimately on the disease burden in Europe. In the present study, a total of 102 B. pertussis isolates from the period 1998 to 2001 from five European countries (Finland, Sweden, Germany, The Netherlands, and France) were characterized. The isolates were analyzed by typing based on variable number of tandem repeats (VNTR); by sequencing of polymorphic genes encoding the surface proteins pertussis toxin S1 and S3 subunits (ptxA and ptxC), pertactin (prn), and tracheal colonization factor (tcfA); and by fimbrial serotyping. The results reveal a relationship between geographic location and VNTR types, the frequency of the ptxC alleles, and serotypes. We have not observed a relationship between the strain characteristics we studied and vaccination programs. Our results provide a baseline which can be used to reveal changes in the B. pertussis population in Europe in the coming years.
PubMed ID
15956406 View in PubMed
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An ethnic role for chronic, but not acute, graft-versus-host disease after HLA-identical sibling stem cell transplantation.

https://arctichealth.org/en/permalink/ahliterature20034
Source
Eur J Haematol. 2001 Jan;66(1):50-6
Publication Type
Article
Date
Jan-2001
Author
M. Remberger
J. Aschan
B. Lönnqvist
S. Carlens
B. Gustafsson
P. Hentschke
S. Klaesson
J. Mattsson
P. Ljungman
O. Ringdén
Author Affiliation
Centre for Allogeneic Stem Cell Transplantation, and Department of Clinical Immunology, Karolinska Institute, Huddinge Hospital, Sweden. Mats.Remberger@impi.ki.se
Source
Eur J Haematol. 2001 Jan;66(1):50-6
Date
Jan-2001
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Africa - ethnology
Aged
Anemia, Aplastic - therapy
Asia - ethnology
Child
Child, Preschool
Chronic Disease
Cytomegalovirus - growth & development
Cytomegalovirus Infections - ethnology - etiology
Europe - ethnology
Fanconi Anemia - therapy
Female
Follow-Up Studies
Graft Survival
Graft vs Host Disease - ethnology - etiology - immunology
HLA Antigens - immunology
Hematopoietic Stem Cell Transplantation - adverse effects
Histocompatibility
Humans
Incidence
Infant
Life tables
Logistic Models
Male
Metabolism, Inborn Errors - therapy
Middle Aged
Minor Histocompatibility Antigens - immunology
Multivariate Analysis
Neoplasms - therapy
Nuclear Family
Recurrence
Research Support, Non-U.S. Gov't
Risk factors
Scandinavia - ethnology
Survival Analysis
Sweden - epidemiology
Virus Activation
Abstract
Among 424 HLA identical siblings undergoing stem cell transplantation, 364 were Scandinavians and 60 represented other ethnic groups. The cumulative probabilities of acute graft-versus-host disease grades II-IV were similar in both groups, 17% in Scandinavians and 12% in the others, p = 0.4. In a multivariate analysis, less effective immune suppression with cyclosporine or methotrexate alone (p = 0.001), recipient seropositive for three to four herpes viruses (p = 0.004), CMV-seropositive recipient (p = 0.05) and early engraftment (before day 15) (p = 0.05) were independent risk-factors for acute GVHD grades II-IV. The cumulative probabilities of chronic GVHD were 47% and 68% in the two ethnic populations, respectively (p = 0.004). In multivariate analysis, higher patient age (p
PubMed ID
11168508 View in PubMed
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233 records – page 1 of 24.