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[The effect of anti-recurrence treatment with isoniazid in combination with etimizol on the immune reactivity of Group III ambulatory care patients].

https://arctichealth.org/en/permalink/ahliterature103718
Source
Probl Tuberk. 1990;(8):3-5
Publication Type
Article
Date
1990
Author
V G Savvateeva
T P Maslauskene
V M Makarova
M G Lokhov
Source
Probl Tuberk. 1990;(8):3-5
Date
1990
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Ambulatory Care
Drug Therapy, Combination
Etimizol - administration & dosage
Female
Humans
Immunity - drug effects
Isoniazid - administration & dosage
Male
Middle Aged
Recurrence
Russia
Tuberculosis, Pulmonary - immunology - prevention & control
Abstract
Findings of immunologic observation of 35 subjects included into Group III of dispensary observation before and after antirecurring treatment with isoniazid and isoniazid in combination with ethymisole are presented. The findings indicate there is inhibition of immune cellular reactions in the above subjects (lower levels of T-suppressors and T-helpers and increased content of O-cells). Unfavorable changes in men are aggravated by suppressing antibody production; higher phagocytic blood activity is also detected. Thus, the antirecurring treatment promoted the normalization of immune reactions.
PubMed ID
2147770 View in PubMed
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[The effect of etimizol on the functional status of the blood coagulation systems and fibrinolysis in workers on expedition-duty watches working under the climatic conditions of northern Tyumen Province].

https://arctichealth.org/en/permalink/ahliterature215241
Source
Eksp Klin Farmakol. 1995 May-Jun;58(3):40-2
Publication Type
Article
Author
S I Bogoslovskaia
G P Gladilin
Source
Eksp Klin Farmakol. 1995 May-Jun;58(3):40-2
Language
Russian
Publication Type
Article
Keywords
Adaptation, Physiological - drug effects
Adult
Blood Coagulation - drug effects
Cold Climate
Etimizol - administration & dosage - pharmacology
Fibrinolysis - drug effects
Humans
Immunity, Innate - drug effects
Lipid Peroxidation - drug effects
Male
Petroleum
Siberia
Time Factors
Abstract
The study was undertaken to reveal the effects of ethymisole on the functional status of blood coagulation and fibrinolytic systems, the body's adaptative reserves of workers from expeditionary-duty teams. Ethymisole was found to normalize the functional status of blood coagulation and fibrinolytic systems, to restore conjunction of their functioning. The use of the drug was ascertained to normalize the activity of lipid peroxidation products, to enhance the adaptative reserves of expeditionary-duty workers by prolonging the resistance phase. It is concluded that ethymisole may be used as an agent that enhances the body's adaptative reserves.
PubMed ID
7663295 View in PubMed
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