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The ESD polymorphism: further studies of the ESD2 and ESD5 allele products.

https://arctichealth.org/en/permalink/ahliterature40811
Source
Hum Genet. 1981;57(4):351-3
Publication Type
Article
Date
1981
Author
B. Olaisen
A. Siverts
R. Jonassen
B. Mevåg
T. Gedde-Dahl
Source
Hum Genet. 1981;57(4):351-3
Date
1981
Language
English
Publication Type
Article
Keywords
Adult
Carboxylesterase
Carboxylic Ester Hydrolases - genetics
Child
Electrophoresis, Agar Gel
Electrophoresis, Polyacrylamide Gel
Erythrocytes - enzymology
Female
Gene Frequency
Genetic Diseases, Inborn - enzymology
Humans
Isoelectric Focusing
Male
Norway
Polymorphism, Genetic
Research Support, Non-U.S. Gov't
Abstract
Electrofocusing and agarose electrophoresis techniques both reveal polymorphism of ESD2, which may be subdivided into two different proteins, coded for by genes allelic to EDS* 1. After agarose electrophoresis, ESD2 is slightly more anodally located than ESD5, while the latter is considerably more acidic as revealed by electrofocusing in polyacrylamide gel slabs. Family studies have confirmed that each of the allele products behave as Mendelian characters; and the gene frequencies in a Norwegian population material are about 0.08 and 0.02 for the ESD*2 and ESD*5 alleles, respectively.
PubMed ID
7286974 View in PubMed
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