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[Pathology of neuroendocrine neoplasms].

https://arctichealth.org/en/permalink/ahliterature135332
Source
Chirurg. 2011 Jul;82(7):567-73
Publication Type
Article
Date
Jul-2011
Author
M. Anlauf
P. Gerlach
M. Schott
A. Raffel
M. Krausch
W T Knoefel
M. Pavel
G. Klöppel
Author Affiliation
Institut für Pathologie, Endokrines Tumorzentrum am Universitätsklinikum Düsseldorf, Moorenstrasse 5, Düsseldorf, Germany. martin.anlauf@med.uni-duesseldorf.de
Source
Chirurg. 2011 Jul;82(7):567-73
Date
Jul-2011
Language
German
Publication Type
Article
Keywords
Cell Proliferation
Digestive System Neoplasms - classification - pathology - surgery
Humans
Neoplasm Grading
Neoplasm Staging
Neuroendocrine Tumors - classification - pathology - surgery
Prognosis
Terminology as Topic
Tumor Markers, Biological - analysis
Abstract
During the last 5 years the European Neuroendocrine Tumor Society (ENETS) has developed basic recommendations for a standardized pathological diagnosis and classification of neuroendocrine neoplasms (NEN) of the gastroenteropancreatic system. These were included in the novel classification of tumors of the digestive system by the World Health Organization (WHO 2010) and the TNM classification of the union for international cancer control (2009). This review presents the pathology diagnosis regarding (1) basic diagnosis, (2) clinically relevant optional diagnosis, (3) proliferation-based grading, (4) nomenclature and (5) TNM classification. It is emphasized that a standardized diagnosis of NEN, together with clinical and radiological findings, is crucial for prognostic stratification and optimal therapy of patients with NEN. Therefore a close interdisciplinary collaboration is essential.
PubMed ID
21487814 View in PubMed
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