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Abundance of the Na-K-2Cl cotransporter NKCC2 is increased by high-fat feeding in Fischer 344 X Brown Norway (F1) rats.

https://arctichealth.org/en/permalink/ahliterature90141
Source
Am J Physiol Renal Physiol. 2009 Apr;296(4):F762-70
Publication Type
Article
Date
Apr-2009
Author
Riazi Shahla
Tiwari Swasti
Sharma Nikhil
Rash Arjun
Ecelbarger C M
Author Affiliation
Associate Professor, Dept. of Medicine, Georgetown Univ., 4000 Reservoir Rd, NW, Washington, DC, 20007, USA.
Source
Am J Physiol Renal Physiol. 2009 Apr;296(4):F762-70
Date
Apr-2009
Language
English
Publication Type
Article
Keywords
Animals
Antioxidants - pharmacology
Biological Markers - urine
Blood pressure
Blotting, Western
Crosses, Genetic
Cyclic N-Oxides - pharmacology
Dietary Fats - administration & dosage - metabolism
Dinoprost - analogs & derivatives - urine
Enzyme Inhibitors - pharmacology
Furosemide - pharmacology
Glucose Intolerance - metabolism - physiopathology
Hypertension - metabolism - physiopathology
Insulin Resistance
Kidney Medulla - drug effects - metabolism
Male
NG-Nitroarginine Methyl Ester - pharmacology
Natriuresis
Nitric Oxide - urine
Nitric Oxide Synthase - antagonists & inhibitors - metabolism
Oxidative Stress
Potassium Channels, Inwardly Rectifying - metabolism
Rats
Rats, Inbred BN
Rats, Inbred F344
Sodium Potassium Chloride Symporter Inhibitors - pharmacology
Sodium-Potassium-Chloride Symporters - antagonists & inhibitors - metabolism
Sodium-Potassium-Exchanging ATPase - metabolism
Spin Labels
Telemetry
Time Factors
Up-Regulation
Abstract
Insulin resistance is associated with hypertension by mechanisms likely involving the kidney. To determine how the major apical sodium transporter of the thick ascending limb, the bumetanide-sensitive Na-K-2Cl cotransporter (NKCC2) is regulated by high-fat feeding, we treated young male, Fischer 344 X Brown Norway (F344BN) rats for 8 wk with diets containing either normal (NF, 4%) or high (HF, 36%) fat, by weight, primarily as lard. HF-fed rats had impaired glucose tolerance, increased urine excretion of 8-isoprostane (a marker of oxidative stress), increased protein levels for NKCC2 (50-125%) and the renal outer medullary potassium channel (106%), as well as increased natriuretic response to furosemide (20-40%). To test the role of oxidative stress in this response, in study 2, rats were fed the NF or HF diet plus plain drinking water, or water containing N(G)-nitro-l-arginine methyl ester (l-NAME), a nitric oxide synthase inhibitor (100 mg/l), or tempol, a superoxide dismutase mimetic (1 mmol/l). The combination of tempol with HF nullified the increase in medullary NKCC2, while l-NAME with HF led to the highest expression of medullary NKCC2 (to 498% of NF mean). However, neither of these drugs dramatically affected the elevated natriuretic response to furosemide with HF. Finally, l-NAME led to a marked increase in blood pressure (measured by radiotelemetry), which was significantly enhanced with HF. Mean arterial blood pressure at 7 wk was as follows (mmHg): NF, 100 +/- 2; NF plus l-NAME, 122 +/- 3; and HF plus l-NAME, 131 +/- 2. Overall, HF feeding increased the abundance of NKCC2. Inappropriately high sodium reabsorption in the thick ascending limb via NKCC2 may contribute to hypertension with insulin resistance.
PubMed ID
19193725 View in PubMed
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Acquired preference especially for dietary fat and obesity: a study of weight-discordant monozygotic twin pairs.

https://arctichealth.org/en/permalink/ahliterature189641
Source
Int J Obes Relat Metab Disord. 2002 Jul;26(7):973-7
Publication Type
Article
Date
Jul-2002
Author
A. Rissanen
P. Hakala
L. Lissner
C-E Mattlar
M. Koskenvuo
T. Rönnemaa
Author Affiliation
Department of Psychiatry, University of Helsinki, Finland.
Source
Int J Obes Relat Metab Disord. 2002 Jul;26(7):973-7
Date
Jul-2002
Language
English
Publication Type
Article
Keywords
Adult
Body Weight
Dietary Fats - administration & dosage
Female
Finland
Food Habits
Food Preferences
Humans
Male
Obesity - epidemiology - psychology
Twins, Monozygotic
Abstract
To determine the independent associations of dietary preference for fat with obesity without the confounding by genetic effects.
Descriptive comparison of the responses of monozygotic twins discordant for obesity to questions concerning current and past preference for dietary fat, current overconsumption of fatty items and recalled food consumption compared to the co-twin.
The Research and Development Centre of the Social Insurance Institution, Finland.
Twenty-three healthy monozygotic twin pairs who were discordant for obesity (BMI difference at least 3 kg/m(2)).
Obesity status of the twin, as a function of the current and recalled dietary preferences and selected psychosocial variables.
The obese twins reported current preference for fatty foods three times more frequently than the lean co-twin. Moreover, when comparing recalled taste for fat at the time the twins left their parental homes, both the obese and lean co-twins consistently recalled that the obese twin had greater preference for fatty foods in young adulthood, and that the lean twin had less. Psychological characteristics of lean and obese co-twins did not differ.
Acquired preference for fatty foods is associated with obesity, independent of genetic background. Modification of fat preferences may be an important step in the prevention of obesity in the general population.
PubMed ID
12080452 View in PubMed
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Adherence to dietary recommendations for Swedish adults across categories of greenhouse gas emissions from food.

https://arctichealth.org/en/permalink/ahliterature293496
Source
Public Health Nutr. 2017 Dec; 20(18):3381-3393
Publication Type
Journal Article
Date
Dec-2017
Author
Camilla Sjörs
Fredrik Hedenus
Arvid Sjölander
Annika Tillander
Katarina Bälter
Author Affiliation
1Department of Medical Epidemiology and Biostatistics (MEB),Karolinska Institutet,Nobels väg 12a,SE-171 77 Stockholm,Sweden.
Source
Public Health Nutr. 2017 Dec; 20(18):3381-3393
Date
Dec-2017
Language
English
Publication Type
Journal Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Body mass index
Carbon Dioxide - analysis
Diet
Diet Records
Dietary Carbohydrates - administration & dosage
Dietary Fats - administration & dosage
Dietary Fiber - administration & dosage
Dietary Proteins - administration & dosage
Exercise
Female
Greenhouse Gases - analysis
Humans
Male
Micronutrients - administration & dosage
Middle Aged
Nutrition Assessment
Nutrition Surveys
Patient compliance
Recommended dietary allowances
Socioeconomic Factors
Surveys and Questionnaires
Sweden
Young Adult
Abstract
To explore associations between diet-related greenhouse gas emissions (GHGE), nutrient intakes and adherence to the Nordic Nutrition Recommendations among Swedish adults.
Diet was assessed by 4d food records in the Swedish National Dietary Survey. GHGE was estimated by linking all foods to carbon dioxide equivalents, using data from life cycle assessment studies. Participants were categorized into quartiles of energy-adjusted GHGE and differences between GHGE groups regarding nutrient intakes and adherence to nutrient recommendations were explored.
Sweden.
Women (n 840) and men (n 627) aged 18-80 years.
Differences in nutrient intakes and adherence to nutrient recommendations between GHGE groups were generally small. The dietary intake of participants with the lowest emissions was more in line with recommendations regarding protein, carbohydrates, dietary fibre and vitamin D, but further from recommendations regarding added sugar, compared with the highest GHGE group. The overall adherence to recommendations was found to be better among participants with lower emissions compared with higher emissions. Among women, 27 % in the lowest GHGE group adhered to at least twenty-three recommendations compared with only 12 % in the highest emission group. For men, the corresponding figures were 17 and 10 %, respectively.
The study compared nutrient intakes as well as adherence to dietary recommendations for diets with different levels of GHGE from a national dietary survey. We found that participants with low-emission diets, despite higher intake of added sugar, adhered to a larger number of dietary recommendations than those with high emissions.
PubMed ID
28879831 View in PubMed
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Adipose tissue fatty acids as biomarkers of dietary exposure in Danish men and women.

https://arctichealth.org/en/permalink/ahliterature24046
Source
Am J Clin Nutr. 1993 May;57(5):629-33
Publication Type
Article
Date
May-1993
Author
A. Tjønneland
K. Overvad
E. Thorling
M. Ewertz
Author Affiliation
Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen.
Source
Am J Clin Nutr. 1993 May;57(5):629-33
Date
May-1993
Language
English
Publication Type
Article
Keywords
Adipose Tissue - metabolism
Adult
Biological Markers - analysis
Denmark - epidemiology
Diet - statistics & numerical data
Dietary Fats - administration & dosage
Fatty Acids - analysis
Female
Humans
Male
Middle Aged
Nutrition Surveys
Research Support, Non-U.S. Gov't
Abstract
Adipose tissue fatty acids, it has been proposed, reflect dietary intake. Using data from a validation study preceding a prospective study on diet, cancer, and health in Denmark, we were able to compare fatty acid profiles in adipose tissue biopsies from 86 individuals (23 men and 63 women) aged 40-64 y and dietary intake of fatty acids (as percentage of total fat) assessed by two 7-d weighed-diet records or by a semi-quantitative food frequency questionnaire. Correlation coefficients (Pearson r) between fatty acid concentrations in adipose tissue biopsies (as percentage of total peak area) and dietary intake of fatty acid (percentage of total fat), determined from the diet records for men and women, respectively, were as follows: polyunsaturated fatty acids r = 0.74 and r = 0.46; n - 3 fatty acids of marine origin: eicosapentaenoic acid r = 0.15 and r = 0.61, and docosahexaenoic acid r = 0.47 and r = 0.57. Correlation coefficients obtained by using the food frequency questionnaire were slightly lower for most fatty acids.
PubMed ID
8480677 View in PubMed
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[An 8-month-long controlled trial of low fat/high fiber diet. Effect on blood lipids and blood pressure in young healthy individuals].

https://arctichealth.org/en/permalink/ahliterature221230
Source
Ugeskr Laeger. 1993 Apr 26;155(17):1289-93
Publication Type
Article
Date
Apr-26-1993
Author
B. Sandström
P. Marckmann
N. Bindslev
Author Affiliation
Landbohøjskolen, Forskningsinstitut for Human Ernaering, Frederiksberg.
Source
Ugeskr Laeger. 1993 Apr 26;155(17):1289-93
Date
Apr-26-1993
Language
Danish
Publication Type
Article
Keywords
Adult
Age Factors
Blood pressure
Denmark
Dietary Fats - administration & dosage
Dietary Fiber - administration & dosage
Female
Food Habits
Humans
Lipids - blood
Male
Time Factors
Notes
Comment In: Ugeskr Laeger. 1993 Jul 19;155(29):2288-98392231
PubMed ID
8389495 View in PubMed
Less detail

Analysis of 24-hour recalls of 164 fourth- to sixth-grade Mohawk children in Kahnawake.

https://arctichealth.org/en/permalink/ahliterature205123
Source
J Am Diet Assoc. 1998 Jul;98(7):814-6
Publication Type
Article
Date
Jul-1998

[Analysis of the nutrition of elderly people in Ukraine]

https://arctichealth.org/en/permalink/ahliterature61588
Source
Vopr Pitan. 2003;72(5):3-7
Publication Type
Article
Date
2003
Author
Iu G Grigorov
Source
Vopr Pitan. 2003;72(5):3-7
Date
2003
Language
Russian
Publication Type
Article
Keywords
Age Factors
Aged
Appetite
Cholesterol - blood
Diet
Dietary Fats - administration & dosage - pharmacology
Dietary Proteins - administration & dosage - pharmacology
Electrocardiography
English Abstract
Female
Food Habits
Humans
Lipids - blood
Male
Middle Aged
Nutrition Policy
Nutrition Surveys
Nutritional Status
Sex Factors
Taste - physiology
Tooth - physiology
Ukraine
Abstract
A comparative analysis of the factual nutrition and health indices for 1970-2001 was made involving 2950 persons aged 60-89 years, residents of Ukraine. The state of nutrition of 530 single non-working citizens of NIS states, being taken care of by a social care service, was studied. The assortment structure of food products is sharply reduced, the contents of main nutrients and biologically active substances are unbalanced. The is conditioned by poor socio-economic of the people of this age category, on the one hand and by age-related changes of the digestive system, taste sensitivity, etc., on the other. It has been shown that more than 15% of older has a protein-energetic malnutrition.
PubMed ID
14619607 View in PubMed
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Apolipoprotein B signal peptide insertion/deletion polymorphism is associated with Ag epitopes and involved in the determination of serum triglyceride levels.

https://arctichealth.org/en/permalink/ahliterature228831
Source
J Lipid Res. 1990 Jul;31(7):1255-61
Publication Type
Article
Date
Jul-1990
Author
C F Xu
M J Tikkanen
J K Huttunen
P. Pietinen
R. Bütler
S. Humphries
P. Talmud
Author Affiliation
Charing Cross Sunley Research Centre, London, U.K.
Source
J Lipid Res. 1990 Jul;31(7):1255-61
Date
Jul-1990
Language
English
Publication Type
Article
Keywords
Adult
Amino Acid Sequence
Analysis of Variance
Apolipoproteins B - genetics - immunology
Base Sequence
Dietary Fats - administration & dosage
Epitopes - genetics
Female
Genes
Genotype
Humans
Linkage Disequilibrium
Male
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Protein Sorting Signals - metabolism
Triglycerides - blood
Abstract
We have investigated the insertion/deletion polymorphism in the signal peptide region of the apoB gene in 106 Finnish individuals from North Karelia. The relative frequency of the insertion allele in this sample was 0.73. Strong linkage disequilibrium was detected between this apoB insertion/deletion polymorphism and the Ag(c/g) epitope pair of apoB, while weak linkage disequilibrium was detected between the polymorphism and the four other reported Ag epitope pairs [(a1/d), (x/y), (h/i) and (t/z)], as well as the apoB PvuII and the XbaI RFLPs. Using one-way analysis of variance there was a statistically significant association (P less than 0.05) between the apoB insertion/deletion polymorphism and serum triglyceride levels in this sample. Individuals homozygous for the insertion allele had higher triglyceride levels than individuals homozygous for the deletion allele, while individuals heterozygous for the polymorphism had intermediate levels. These differences were reduced when individuals were consuming a low fat diet but were statistically significant when the individuals returned to their normal diet. It is possible that insertion or deletion of three hydrophobic amino acids (leu-ala-leu) from the signal peptide of apoB may have a direct effect on plasma triglyceride levels by altering the intracellular processing of apoB or apoB-containing lipoproteins in the liver or intestine.
PubMed ID
1698214 View in PubMed
Less detail

[A quantitative assessment of the impact of diet on the mortality of heart disease in Denmark. Estimation of etiologic fraction]

https://arctichealth.org/en/permalink/ahliterature10365
Source
Ugeskr Laeger. 2000 Sep 11;162(37):4921-5
Publication Type
Article
Date
Sep-11-2000
Author
M. Osler
J. Godtfredsen
M N Grønbaek
P. Marckmann
O K Overvad
Author Affiliation
Københavns Universitet, Panum Instituttet, afdeling for social medicin og psykosocial sundhed (Institut for Folkesundhedsvidenskab).
Source
Ugeskr Laeger. 2000 Sep 11;162(37):4921-5
Date
Sep-11-2000
Language
Danish
Publication Type
Article
Keywords
Alcohol Drinking
Coronary Disease - etiology - mortality
Denmark - epidemiology
Dietary Fats - administration & dosage
English Abstract
Food Habits
Fruit
Guidelines
Humans
Myocardial Ischemia - etiology - mortality
Risk assessment
Risk factors
Vegetables
Abstract
INTRODUCTION: The aim of the present study was to quantify the impact of different dietary factors on the mortality from ischaemic heart disease in Denmark. METHODS: Relative risks and knowledge on the distribution of different dietary factors were used to estimate etiological fractions. RESULTS: It is estimated that an intake of fruit and vegetables and saturated fat as recommended would prevent 12 and 22%, respectively, of deaths from ischaemic heart disease in Denmark. An intake of fish among those at high risk for ischaemic heart disease, would lead to a 26% lower mortality, while alcohol intake among abstainers would have no significant quantitative effect. DISCUSSION: These results suggest that changes in dietary habits according to current recommendations would have an impact on public health in Denmark.
PubMed ID
11002740 View in PubMed
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490 records – page 1 of 49.