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177 records – page 1 of 18.

The 24-hour pulse wave velocity, aortic augmentation index, and central blood pressure in normotensive volunteers.

https://arctichealth.org/en/permalink/ahliterature104335
Source
Vasc Health Risk Manag. 2014;10:247-51
Publication Type
Article
Date
2014
Author
Tatyana Y Kuznetsova
Viktoria A Korneva
Evgeniya N Bryantseva
Vitaliy S Barkan
Artemy V Orlov
Igor N Posokhov
Anatoly N Rogoza
Author Affiliation
Faculty of Medicine, Petrozavodsk State University, Petrozavodsk, Russia.
Source
Vasc Health Risk Manag. 2014;10:247-51
Date
2014
Language
English
Publication Type
Article
Keywords
Adult
Aged
Algorithms
Blood pressure
Blood Pressure Monitoring, Ambulatory - standards
Circadian Rhythm
Diastole
Female
Healthy Volunteers
Heart rate
Humans
Male
Middle Aged
Predictive value of tests
Pulse Wave Analysis - standards
Reference Values
Russia
Signal Processing, Computer-Assisted
Systole
Time Factors
Vascular Stiffness
Abstract
The purpose of this study was to examine the pulse wave velocity, aortic augmentation index corrected for heart rate 75 (AIx@75), and central systolic and diastolic blood pressure during 24-hour monitoring in normotensive volunteers. Overall, 467 subjects (206 men and 261 women) were recruited in this study. Participants were excluded from the study if they were less than 19 years of age, had blood test abnormalities, had a body mass index greater than 2 7.5 kg/m(2), had impaired glucose tolerance, or had hypotension or hypertension. Ambulatory blood pressure monitoring (ABPM) with the BPLab(®) device was performed in each subject. ABPM waveforms were analyzed using the special automatic Vasotens(®) algorithm, which allows the calculation of pulse wave velocity, AIx@75, central systolic and diastolic blood pressure for "24-hour", "awake", and "asleep" periods. Circadian rhythms and sex differences in these indexes were identified. Pending further validation in prospective outcome-based studies, our data may be used as preliminary diagnostic values for the BPLab ABPM additional index in adult subjects.
Notes
Cites: J Invasive Cardiol. 2009 Jun;21(6):270-719494403
Cites: Hypertens Res. 2012 Oct;35(10):980-722622282
Cites: Am J Hypertens. 2010 Feb;23(2):180-519959999
Cites: J Hypertens. 2013 Jul;31(7):1281-35723817082
Cites: Vasc Health Risk Manag. 2011;7:649-5622140314
Cites: Age (Dordr). 2013 Dec;35(6):2345-5523319362
Cites: Hypertension. 2013 Jun;61(6):1148-923630945
Cites: Hypertension. 2013 Jun;61(6):1168-7623630950
Cites: J Hypertens. 2013 Sep;31(9):1731-6824029863
Cites: Eur Heart J. 2010 Oct;31(19):2338-5020530030
PubMed ID
24812515 View in PubMed
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Abnormal echocardiography in patients with type 2 diabetes and relation to symptoms and clinical characteristics.

https://arctichealth.org/en/permalink/ahliterature286353
Source
Diab Vasc Dis Res. 2016 Sep;13(5):321-30
Publication Type
Article
Date
Sep-2016
Author
Peter Godsk Jørgensen
Magnus T Jensen
Rasmus Mogelvang
Bernt Johan von Scholten
Jan Bech
Thomas Fritz-Hansen
Søren Galatius
Tor Biering-Sørensen
Henrik U Andersen
Tina Vilsbøll
Peter Rossing
Jan S Jensen
Source
Diab Vasc Dis Res. 2016 Sep;13(5):321-30
Date
Sep-2016
Language
English
Publication Type
Article
Keywords
Aged
Denmark - epidemiology
Diabetes Mellitus, Type 2 - diagnosis - epidemiology
Diastole
Echocardiography, Doppler
Electrocardiography
Female
Humans
Hypertrophy, Left Ventricular - diagnostic imaging - epidemiology - physiopathology
Male
Middle Aged
Outpatients
Predictive value of tests
Prevalence
Risk factors
Ventricular Dysfunction, Left - diagnostic imaging - epidemiology - physiopathology
Ventricular Function, Left
Abstract
We aimed to determine the prevalence of echocardiographic abnormalities and their relation to clinical characteristics and cardiac symptoms in a large, contemporary cohort of patients with type 2 diabetes.
A total of 1030 patients with type 2 diabetes participated. Echocardiographic abnormalities were present in 513 (49.8%) patients, mainly driven by a high prevalence of diastolic dysfunction 178 (19.4%), left ventricular hypertrophy 213 (21.0%) and left atrial enlargement, 200 (19.6%). The prevalence increased markedly with age from 31.1% in the youngest group (75?years) (p?
PubMed ID
27208801 View in PubMed
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ACE inhibitors captopril and enalapril induce regression of left ventricular hypertrophy in hypertensive patients with chronic renal failure.

https://arctichealth.org/en/permalink/ahliterature54522
Source
Nephrol Dial Transplant. 1997 May;12(5):945-51
Publication Type
Article
Date
May-1997
Author
A I Dyadyk
A E Bagriy
I A Lebed
N F Yarovaya
E V Schukina
G G Taradin
Author Affiliation
Department of Postgraduate Therapy Training, Medical University, Donetsk, Ukraine.
Source
Nephrol Dial Transplant. 1997 May;12(5):945-51
Date
May-1997
Language
English
Publication Type
Article
Keywords
Adult
Angiotensin-Converting Enzyme Inhibitors - adverse effects - therapeutic use
Blood Pressure - drug effects
Captopril - adverse effects - therapeutic use
Diastole - drug effects
Drug Tolerance
Enalapril - adverse effects - therapeutic use
Female
Hemodynamic Processes - drug effects
Humans
Hypertension - complications - drug therapy - physiopathology
Hypertrophy, Left Ventricular - complications - drug therapy - pathology
Kidney Failure, Chronic - complications
Male
Middle Aged
Prospective Studies
Single-Blind Method
Systole - drug effects
Ventricular Function, Left - drug effects
Abstract
BACKGROUND: Left ventricular hypertrophy is frequently noted in patients with moderate to severe chronic renal failure not requiring dialysis. Recently, several studies have shown reversal of myocardial hypertrophy in end-stage renal disease with long-term pharmacological control of blood pressure, but it is unclear whether left ventricular mass regresses or normalizes with antihypertensive treatment of patients with earlier stages of chronic renal failure. METHODS: Seventy-two undialysed patients with chronic renal failure, chronic mild-to-moderate hypertension, and left ventricular hypertrophy were randomly assigned in a prospective study to either the captopril (n = 36) or enalapril group (n = 36). Blood pressure measurements, echocardiographic and Doppler parameters were evaluated before treatment and at 6 and 12 months of therapy. RESULTS: During follow-up, six patients developed side-effects including dry cough, taste disturbances, skin rash and gastric intolerance. In the captopril group there was a decrease in mean left ventricular mass index by 12% after 6 months of treatment, which decreased by 20% after 12 months treatment. For enalapril, the average reduction of myocardial mass after 6 months treatment was 14% and after 12 months treatment, the decrease was 19%. In both treatment groups there was significant improvement of left ventricular filling dynamics. No deterioration of left ventricular systolic function was observed. CONCLUSIONS: Our results confirm that antihypertensive monotherapy with the ACE inhibitors, captopril and enalapril, in patients with chronic renal failure results in regression of left ventricular mass index associated with a significant improvement in the diastolic function of the left ventricle without a demonstrable deterioration in left ventricular systolic performance.
PubMed ID
9175047 View in PubMed
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Acute effects on the ventricular function in Swedish snuffers: an echocardiographic study.

https://arctichealth.org/en/permalink/ahliterature127427
Source
Clin Physiol Funct Imaging. 2012 Mar;32(2):106-13
Publication Type
Article
Date
Mar-2012
Author
D. Sundström
M. Waldenborg
K. Emilsson
Author Affiliation
Department of Clinical Physiology, Örebro University Hospital, Örebro, Sweden. daniel.sundstrom@orebroll.se
Source
Clin Physiol Funct Imaging. 2012 Mar;32(2):106-13
Date
Mar-2012
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Blood pressure
Diastole
Echocardiography, Doppler
Echocardiography, Doppler, Color
Echocardiography, Doppler, Pulsed
Female
Heart rate
Humans
Male
Middle Aged
Predictive value of tests
Stroke Volume
Sweden
Systole
Time Factors
Tobacco, Smokeless - adverse effects
Ventricular Dysfunction, Left - etiology - physiopathology - ultrasonography
Ventricular Dysfunction, Right - etiology - physiopathology - ultrasonography
Ventricular Function, Left
Ventricular Function, Right
Young Adult
Abstract
Cigarettes and Swedish snuff contain nicotine, which influence the cardiovascular system. Cigarette smoke has been shown to give an acute impairment in diastolic heart parameters. The systolic and diastolic heart function in snuff users is not thoroughly enough investigated. The aim of this study was to investigate if Swedish snuff will give an acute decrease in systolic and diastolic heart parameters in the left and right ventricles in healthy Swedish snuffers.
Thirty healthy volunteers were examined with echocardiography. The study involved recordings from four different times: before snuff intake, 5 and 30 min after intake and finally 30 min after snuff withdrawal. The systolic and diastolic heart parameters were collected with conventional echocardiographic methods. In addition, the heart frequency and blood pressure response were measured. The pulse and blood pressure response were significantly altered (P
PubMed ID
22296630 View in PubMed
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Age dependency in the timing of mitral annular motion in relation to ventricular filling in healthy subjects: Umea General Population Heart Study.

https://arctichealth.org/en/permalink/ahliterature157109
Source
Eur J Echocardiogr. 2008 Jul;9(4):522-9
Publication Type
Article
Date
Jul-2008
Author
F. Bukachi
A. Waldenström
S. Mörner
P. Lindqvist
M Y Henein
E. Kazzam
Author Affiliation
Department of Medical Physiology, College of Health Sciences, Nairobi, Kenya.
Source
Eur J Echocardiogr. 2008 Jul;9(4):522-9
Date
Jul-2008
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Aged, 80 and over
Aging
Diastole - physiology
Echocardiography, Doppler
Female
Humans
Male
Middle Aged
Mitral Valve - physiology - ultrastructure
Time Factors
Ventricular Function
Ventricular Function, Left - physiology
Abstract
Peak left ventricular (LV) relaxation normally precedes peak filling (E), which supports the hypothesis that LV suction contributes to early-diastolic filling. The significance of similar temporal discordance in late diastole has previously not been studied. We describe the time relationships between mitral annular motion and LV filling in early and late diastole and examine the effect of normal ageing on these time intervals.
A total of 128 healthy subjects aged 25-88 years were studied. Transmitral and pulmonary venous flow reversals (Ar) were recorded by Doppler echocardiography. Mitral annular diastolic displacement-early (E(m)) and late (A(m))-were recorded by Doppler tissue imaging. With reference to electrocardiographic R and P-waves, the following measurements were made: R to peak E-wave (R-E) and E(m) (R-E(m)); onset P to peak A-wave (P-pA), A(m) (P-pA(m)), and Ar (P-pAr). The differences between [(R-E) and (R-E(m))] for early-diastolic temporal discordance (EDTD) and [(P-A) and (P-A(m))] for late-diastolic temporal discordance (LDTD) were calculated. Isovolumic relaxation time (IVRT) was also measured. Early-diastolic temporal discordance was approximately 26 ms in all age groups. Late-diastolic temporal discordance, however, was inversely related to age (r = -0.35, P
PubMed ID
18490308 View in PubMed
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AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study.

https://arctichealth.org/en/permalink/ahliterature197889
Source
Am J Physiol Heart Circ Physiol. 2000 Jul;279(1):H368-74
Publication Type
Article
Date
Jul-2000
Author
T. Rankinen
J. Gagnon
L. Pérusse
Y C Chagnon
T. Rice
A S Leon
J S Skinner
J H Wilmore
D C Rao
C. Bouchard
Author Affiliation
Pennington Biomedical Research Center, Human Genomics Laboratory, Baton Rouge, Louisiana 70808, USA.
Source
Am J Physiol Heart Circ Physiol. 2000 Jul;279(1):H368-74
Date
Jul-2000
Language
English
Publication Type
Article
Keywords
Adult
Amino Acid Substitution
Angiotensinogen - genetics
Blood Pressure - genetics - physiology
Canada
Cohort Studies
DNA Transposable Elements
Diastole
European Continental Ancestry Group
Exercise - physiology
Female
Genotype
Humans
Male
Oxygen consumption
Peptidyl-Dipeptidase A - genetics
Physical Exertion - physiology
Polymorphism, Genetic
Sequence Deletion
Sex Characteristics
Systole
United States
Abstract
We investigated the association between angiotensinogen (AGT) and angiotensin-converting enzyme (ACE) gene polymorphisms and exercise training responses of resting and exercise blood pressure (BP). BP at rest and during submaximal (50 watts) and maximal exercise tests was measured before and after 20 wk of endurance training in 476 sedentary normotensive Caucasian subjects from 99 families. AGT M235T and ACE insertion/deletion polymorphisms were typed with PCR-based methods. Men carrying the AGT MM and MT genotypes showed 3. 7 +/- 0.6 and 3.2 +/- 0.5 (SE) mmHg reductions, respectively, in diastolic BP at 50 watts (DBP(50)), whereas, in the TT homozygotes, the decrease was 0.4 +/- 1.0 mmHg (P = 0.016 for trend, adjusted for age, body mass index, and baseline DBP(50)). Men with the ACE DD genotype showed a slightly greater decrease in DBP(50) (4.4 +/- 0.6 mmHg) than the II and ID genotypes (2.8 +/- 0.7 and 2.4 +/- 0.5 mmHg, respectively, P = 0.050). Furthermore, a significant (P = 0.022) interaction effect between the AGT and ACE genes was noted for DBP(50); the AGT TT homozygotes carrying the ACE D allele showed no response to training. Men with the AGT TT genotype had greater (P = 0.007) diastolic BP (DBP) response to acute maximal exercise at baseline. However, the difference disappeared after the training period. No associations were found in women. These data suggest that, in men, the genetic variation in the AGT locus modifies the responsiveness of submaximal exercise DBP to endurance training, and interactions between the AGT and ACE loci can alter this response.
PubMed ID
10899077 View in PubMed
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Ambulatory versus home blood pressure monitoring: frequency and determinants of blood pressure difference and diagnostic disagreement.

https://arctichealth.org/en/permalink/ahliterature310069
Source
J Hypertens. 2019 10; 37(10):1974-1981
Publication Type
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Date
10-2019
Author
Angeliki Ntineri
Teemu J Niiranen
Richard J McManus
Annika Lindroos
Antti Jula
Claire Schwartz
Anastasios Kollias
Emmanuel A Andreadis
George S Stergiou
Author Affiliation
Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Athens, Greece.
Source
J Hypertens. 2019 10; 37(10):1974-1981
Date
10-2019
Language
English
Publication Type
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Keywords
Adult
Aged
Antihypertensive Agents - therapeutic use
Blood pressure
Blood Pressure Determination - methods
Blood Pressure Monitoring, Ambulatory - statistics & numerical data
Cardiovascular Diseases - diagnosis
Cross-Sectional Studies
Diastole
Female
Finland
Greece
Humans
Hypertension - diagnosis - drug therapy
Male
Middle Aged
Systole
United Kingdom
Abstract
Out-of-office blood pressure evaluation assessed using ambulatory (ABP) or home (HBP) monitoring is currently recommended for hypertension management. We evaluated the frequency and determinants of diagnostic disagreement between ABP and HBP measurements.
Cross-sectional data from 1971 participants (mean age 53.8?±?11.4 years, 52.6% men, 32% treated) from Greece, Finland and the United Kingdom were analyzed. The diagnostic disagreement between HBP and daytime ABP was regarded as certain when (i) the two methods diagnosed a different blood pressure phenotype, (ii) the absolute HBP-ABP difference was more than 10/5?mmHg (systolic/diastolic) and (iii) ABP and HBP had a more than 5?mmHg difference from the respective hypertension threshold.
In 1574 participants (79.9%), there was agreement between HBP and ABP in diagnosing hypertensive phenotypes (kappa 0.70). Of the remaining 397 participants (20.1%) with diagnostic disagreement, 95 had clinically irrelevant HBP-ABP differences, which reduced the disagreement to 15.3%. When cases with ABP and/or HBP differing =5?mmHg from the respective hypertension threshold were excluded, the certain disagreement between the two methods was reduced to 8.2%. Significant determinants of the HBP-ABP difference were age, sex, study center, BMI, cardiovascular disease history, office hypertension and antihypertensive treatment. Antihypertensive drug treatment, alcohol consumption and office normotension independently increased the odds of diagnostic disagreement.
These data suggest that there is considerable diagnostic agreement between HBP and ABP, and that these methods are interchangeable for clinical decisions in most patients. However, considerable disagreement between the two methods occurs in an appreciable minority, most likely due to methodological and patient-related factors.
PubMed ID
31415001 View in PubMed
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An echocardiographic evaluation of patients with idiopathic heart failure.

https://arctichealth.org/en/permalink/ahliterature54794
Source
Chest. 1995 Mar;107(3):680-9
Publication Type
Article
Date
Mar-1995
Author
B. Andersson
K. Caidahl
F. Waagstein
Author Affiliation
Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Göteborg University, Sweden.
Source
Chest. 1995 Mar;107(3):680-9
Date
Mar-1995
Language
English
Publication Type
Article
Keywords
Adult
Aged
Cardiomyopathy, Dilated - ultrasonography
Diastole - physiology
Dilatation, Pathologic
Echocardiography
Female
Heart Failure, Congestive - physiopathology - ultrasonography
Humans
Male
Middle Aged
Sensitivity and specificity
Stroke Volume
Systole - physiology
Ventricular Dysfunction, Left - ultrasonography
Abstract
The primary myocardial disease idiopathic dilated cardiomyopathy (IDCM) is not clearly defined in the literature. The description is both morphologic and etiologic. We examined consecutive patients with congestive heart failure (CHF) of unknown cause to identify possible cases of IDCM and to give a detailed description of echocardiographic data and possible diastolic dysfunction in this group. The hospital records of patients aged 16 to 65 years hospitalized due to CHF or IDCM during a 6-year period (N = 2,711) were evaluated in a defined region of western Sweden. Twenty-two percent (584/2,711) of these records contained no plausible cause of CHF or IDCM, and among patients being alive, obvious cause was lacking in 411 of 1,516 (27%). These 411 patients were offered a diagnostic investigation, including echocardiography, and they were compared with a randomly selected control group (n = 103) from the general population. Of 411 patients, 293 accepted investigation. From the control group, we defined the reference level for left ventricular (LV) dilatation to be > 32 mm/m2, and reduced ejection fraction according to Teichholz formula to be
PubMed ID
7874937 View in PubMed
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[Antegrade diastolic blood flow and classic reflux in varicose dilatation of the intersaphenous vein].

https://arctichealth.org/en/permalink/ahliterature275525
Source
Angiol Sosud Khir. 2016;22(2):101-8
Publication Type
Article
Date
2016
Author
E V Shaidakov
D A Rosukhovsky
A G Grigoryan
V L Bulatov
E A Ilyukhin
Source
Angiol Sosud Khir. 2016;22(2):101-8
Date
2016
Language
Russian
Publication Type
Article
Keywords
Adult
Diastole
Dilatation, Pathologic - diagnosis - epidemiology - etiology - physiopathology
Female
Hemodynamics
Humans
Leg - blood supply
Male
Prevalence
Regional Blood Flow
Russia
Saphenous Vein - physiopathology - ultrasonography
Severity of Illness Index
Ultrasonography, Doppler, Duplex - methods
Varicose Veins - complications - diagnosis - physiopathology
Venous Insufficiency - diagnosis - epidemiology - etiology - physiopathology
Abstract
In the intersaphenous vein (ISV) there may take place the so-called "antegrade" or "paradoxical" reflux. This type of blood flow is revealed in a series of patients during muscular diastole and is a link of the pathogenesis of varicose disease, but has, as distinct from the "classical" reflux, an antegrade direction. An incompetent saphenopopliteal junction (SPJ) is a source of the antegrade diastolic blood flow (ADBF) through the ISV. Descriptions of possible variants of impaired blood flow through the ISV are fragmentary and their interpretations are controversial. Prevalence and pathogenesis of these disorders impairments have not yet been studied.
A cross-sectional study: over 4 years three centres examined a total of 1,413 patients diagnosed with class C2-C6 varicose veins according the CEAP classification. All patients underwent ultrasound duplex scanning of lower limb veins. The ADBF was determined as a unidirectional antegrade blood flow with the duration of not more than 0.5 second, observed after the crus was relived of compression (in the diastole). Of the patients included into the study who had no varicose veins on the contralateral extremity with the ISV being spotted we sequentially selected 40 subjects including them into the Study Group for the analysis of blood flow and the diameter of the ISV in health.
Impairments of blood flow in the ISV were revealed in 61 (4.8%) of 1,265 extremities included into the study: the "classical" reflux in 9 (14.8%) limbs, ADBF was revealed in 37 (60.7%) limbs, a combination of the "classical" blood flow and ADBF - in 15 (24.6%) limbs. Hence, the patients were subdivided into three groups. Studying the nature of blood flow through the ISV in the control group on 40 lower limbs revealed no blood flow disorders. The mean ISV diameter amounted to 1.68 mm (ME=1 mm). The ISV diameter was considerably higher in all studied groups as compared with the control one (p
PubMed ID
27336341 View in PubMed
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Are left ventricular mass, geometry and function related to vascular changes and/or insulin resistance in long-standing hypertension? ICARUS: a LIFE substudy.

https://arctichealth.org/en/permalink/ahliterature53541
Source
J Hum Hypertens. 2003 May;17(5):305-11
Publication Type
Article
Date
May-2003
Author
M H Olsen
E. Hjerkinn
K. Wachtell
A. Høieggen
J N Bella
S D Nesbitt
E. Fossum
S E Kjeldsen
S. Julius
H. Ibsen
Author Affiliation
Department of Clinical Physiology and Nuclear Medicine, Glostrup University Hospital, Copenhagen, Denmark. mho@dadlnet.dk
Source
J Hum Hypertens. 2003 May;17(5):305-11
Date
May-2003
Language
English
Publication Type
Article
Keywords
Aged
Blood Flow Velocity - physiology
Blood Glucose - metabolism
Blood Pressure - physiology
Carotid Artery, Common - physiopathology
Comparative Study
Denmark
Diastole - physiology
Echocardiography
Female
Heart Ventricles - metabolism - physiopathology - ultrasonography
Humans
Hypertension - metabolism - physiopathology
Hypertrophy, Left Ventricular - metabolism - physiopathology
Insulin - blood
Insulin Resistance - physiology
Male
Middle Aged
Norway
Research Support, Non-U.S. Gov't
Sex Factors
Statistics
Stroke Volume - physiology
Systole - physiology
United States
Vascular Resistance - physiology
Ventricular Function, Left - physiology
Ventricular Remodeling - physiology
Abstract
Vascular hypertrophy and insulin resistance have been associated with abnormal left ventricular (LV) geometry in population studies. We wanted to investigate the influence of vascular hypertrophy and insulin resistance on LV hypertrophy and its function in patients with hypertension. In 89 patients with essential hypertension and electrocardiographic LV hypertrophy, we measured blood pressure; insulin sensitivity by hyperinsulinaemic euglucaemic clamp; minimal forearm vascular resistance (MFVR) by plethysmography; intima-media cross-sectional area of the common carotid arteries (IMA) by ultrasound; and LV mass, relative wall thickness (RWT), systolic function and diastolic filling by echocardiography after two weeks of placebo treatment. LV mass index correlated to IMA/height (r=0.36, P=0.001), serum insulin (r=-0.25, P
Notes
Comment In: J Hum Hypertens. 2003 May;17(5):299-30412756401
PubMed ID
12756402 View in PubMed
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177 records – page 1 of 18.