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Association between maternal pre-existing or gestational diabetes and health problems in children.

https://arctichealth.org/en/permalink/ahliterature32014
Source
Acta Paediatr. 2001 Jul;90(7):746-50
Publication Type
Article
Date
Jul-2001
Author
A. Aberg
L. Westbom
Author Affiliation
Department of Obstetrics and Gynaecologic, University Hospital of Lund, Sweden.
Source
Acta Paediatr. 2001 Jul;90(7):746-50
Date
Jul-2001
Language
English
Publication Type
Article
Keywords
Child
Child Development
Child, Preschool
Diabetes, Gestational - complications - diagnosis
Diagnosis, Differential
Female
Health status
Hospitalization - statistics & numerical data
Humans
Infant
Infant, Newborn
Male
Pregnancy
Pregnancy in Diabetics - complications - diagnosis
Reproducibility of Results
Risk factors
Sweden
Abstract
There is general consensus that children of women with pre-existing diabetes mellitus (PDM) have an increased risk of malformations and neurodevelopmental problems. Whether this is also true for children of women with gestational diabetes mellitus (GDM) is a matter of debate. This study investigated inpatient hospital care up to 10 y of age of children born to GDM and PDM women as a rough estimate of child morbidity. Hospital care of children born to 82,684 GDM women, 3,874 PDM women and 1,213,957 controls was compared by linking the Swedish Medical Birth Registry with the Hospital Discharge Registry. Similar comparisons were performed in a local well-controlled group of 326 children born to GDM women in the Lund area. Children of PDM women and to a lesser degree children of GDM women had a statistically significant increase in hospitalizations, evident at least up to 10 y of age. Significantly increased risks of hospitalization were found for neurological/developmental disorders [odds ratio (OR) 2.30 and 1.36 for PDM and GDM, respectively)], malformations (OR 2.05 and 1.23), infections (OR 1.56 and 1.20) and accidents (OR 1.32 and 1.14). CONCLUSION: The high hospitalization rates of these children indicate an increased morbidity, including neurodevelopmental disorders.
PubMed ID
11519976 View in PubMed
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Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes.

https://arctichealth.org/en/permalink/ahliterature272533
Source
PLoS One. 2015;10(7):e0133672
Publication Type
Article
Date
2015
Author
Stine B Thomsen
Anette P Gjesing
Camilla N Rathcke
Claus T Ekstrøm
Hans Eiberg
Torben Hansen
Oluf Pedersen
Henrik Vestergaard
Source
PLoS One. 2015;10(7):e0133672
Date
2015
Language
English
Publication Type
Article
Keywords
Adipokines - blood
Adult
Anthropometry
Biomarkers - blood
Comorbidity
Denmark
Diabetes Complications - diagnosis
Diabetes Mellitus, Type 2 - blood - diagnosis
Dyslipidemias - metabolism
Female
Genetic Predisposition to Disease
Glucose Tolerance Test
Homeostasis
Humans
Inflammation
Insulin Resistance
Lectins - blood
Male
Middle Aged
Obesity - complications - metabolism
Risk factors
Triglycerides - blood
Waist-Hip Ratio
Abstract
Circulating levels of the inflammatory marker YKL-40 are elevated in cardiovascular disease and obesity-related type 2 diabetes (T2D), and serum YKL-40 levels are related to elements of dyslipidaemia.
We aimed to investigate the associations between serum YKL-40 and obesity-related traits in a Danish sample of non-diabetic relatives to T2D patients and, furthermore, to estimate the heritability of YKL-40.
324 non-diabetic individuals with family relation to a T2D patient were included in the study. The participants underwent oral- and intravenous glucose tolerance tests for estimation of glucose tolerance and surrogate measures of insulin sensitivity. Anthropometric measures were retrieved and biochemical measures of the plasma lipid profile and serum YKL-40 levels were obtained. Association-analyses between serum YKL-40 and obesity-related traits and estimates of the narrow sense heritability of YKL-40 were based on a polygenic variance component model.
Fasting serum levels of YKL-40 were positively associated with waist-hip-ratio (p
Notes
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PubMed ID
26197239 View in PubMed
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Blood pressure levels and risk of cardiovascular events and mortality in type-2 diabetes: cohort study of 34 009 primary care patients.

https://arctichealth.org/en/permalink/ahliterature114320
Source
J Hypertens. 2013 Aug;31(8):1603-10
Publication Type
Article
Date
Aug-2013
Author
Johan Sundström
Reza Sheikhi
Carl J Ostgren
Bodil Svennblad
Johan Bodegård
Peter M Nilsson
Gunnar Johansson
Author Affiliation
Department of Medical Sciences, Uppsala University Hospital, SE-75185 Uppsala, Sweden. johan.sundstrom@medsci.uu.se
Source
J Hypertens. 2013 Aug;31(8):1603-10
Date
Aug-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Antihypertensive Agents - chemistry
Blood pressure
Blood Pressure Determination
Cardiovascular Diseases - mortality - physiopathology
Cohort Studies
Diabetes Complications - diagnosis
Diabetes Mellitus, Type 2 - diagnosis - physiopathology
Female
Follow-Up Studies
Humans
Hypertension - complications - physiopathology
Male
Middle Aged
Multivariate Analysis
Primary Health Care - organization & administration
Registries
Retrospective Studies
Risk
Sweden
Abstract
The optimal blood pressure (BP) in persons with type-2 diabetes is debated. We investigated shapes of the associations of SBP and DBP levels with risk of cardiovascular events and mortality in a large primary care-based sample of diabetic patients.
We investigated all 34?009 consecutive cardiovascular disease-free type-2 diabetes patients aged 35 years or older (mean age 64 years) at 84 primary care centers in central Sweden between 1999 and 2008. We followed this cohort until the end of 2009 in national registries for the incidence of major cardiovascular events (a composite endpoint of myocardial infarction, stroke, heart failure, or cardiovascular mortality) or total mortality.
During up to 11 years of follow-up, 6344 patients (18.7%) had a first cardiovascular event, and 6235 died (18.3%). The associations of annually updated SBP and DBP with risk of major cardiovascular events were U-shaped. The lowest risk of cardiovascular events was observed at a SBP of 135-139?mmHg and a DBP of 74-76?mmHg, and the lowest mortality risk at a SBP of 142-150?mmHg and a DBP of 78-79?mmHg, in both antihypertensive drug-untreated and drug-treated persons.
In a large primary care-based sample of patients with type-2 diabetes, associations of SBP and DBP with risk of major cardiovascular events and mortality were U-shaped. This may have implications for risk stratification of persons with diabetes.
Notes
Comment In: J Hypertens. 2013 Aug;31(8):1527-823822923
PubMed ID
23625112 View in PubMed
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Causes of death in childhood-onset Type 1 diabetes: long-term follow-up.

https://arctichealth.org/en/permalink/ahliterature290006
Source
Diabet Med. 2017 01; 34(1):56-63
Publication Type
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Date
01-2017

Clinical guidelines about diabetes and the accuracy of peer information in an unmoderated online health forum for retired persons.

https://arctichealth.org/en/permalink/ahliterature151202
Source
Inform Health Soc Care. 2009 Mar;34(2):91-9
Publication Type
Article
Date
Mar-2009
Author
Laurie Hoffman-Goetz
Lorie Donelle
Maria D Thomson
Author Affiliation
Faculty of Applied Health Sciences, Department of Health Studies and Gerontology, University of Waterloo, Waterloo, Ontario, Canada. lhgoetz@uwaterloo.ca
Source
Inform Health Soc Care. 2009 Mar;34(2):91-9
Date
Mar-2009
Language
English
Publication Type
Article
Keywords
Canada
Communication
Consumer Health Information - methods
Diabetes Complications - diagnosis - prevention & control
Diabetes mellitus, type 2 - therapy
Diet
Exercise
Humans
Internet
Peer Group
Practice Guidelines as Topic
Abstract
The objective of this study was to determine whether peer recommendations made in response to user queries about non-insulin dependent type II diabetes in an online health forum for retired persons were in agreement with diabetes clinical practice guidelines. A content analysis was conducted on type II diabetes conversations occurring in an online health forum for Canadian retired persons from 1 January to 31 December 2006. Recommendations responding to posted questions about diabetes were compared with published Canadian diabetes clinical practice guidelines. Seven diabetes-related questions generated 17 responses and 35 recommendations. Comparison of recommendations with evidence-based sources indicated that 91% (32/35) were in agreement with the best practice clinical guidelines for type II diabetes. Discussion themes included diabetic signs and symptoms, glycemic control, neuropathy, retinopathy, diet and physical activity recommendations and interactions of prednisone with glucose control. Concerns about the accuracy of online peer recommendations about type II diabetes care and management have not supported these results. This forum presents information sharing among a group of knowledgeable older adults with high interactive health literacy skills. Future research is needed to determine whether deviations from 'accurate' online information are truly harmful or represent lay expert adaptations to self-care routines.
PubMed ID
19412842 View in PubMed
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Clinical management of type 2 diabetes in indigenous youth.

https://arctichealth.org/en/permalink/ahliterature146925
Source
Pediatr Clin North Am. 2009 Dec;56(6):1441-59
Publication Type
Article
Date
Dec-2009
Author
Elizabeth A C Sellers
Kelly Moore
Heather J Dean
Author Affiliation
Department of Pediatrics and Child Health, University of Manitoba, FE-307, 685 William Avenue, Winnipeg, Manitoba R3E 0Z2, Canada. esellers@exchange.hsc.mb.ca
Source
Pediatr Clin North Am. 2009 Dec;56(6):1441-59
Date
Dec-2009
Language
English
Publication Type
Article
Keywords
Adolescent
Blood Glucose - metabolism
Body Weight
Child
Comorbidity
Diabetes Complications - diagnosis - therapy
Diabetes Mellitus, Type 2 - complications - diagnosis - diet therapy - drug therapy - prevention & control - therapy
Health Services, Indigenous - organization & administration - standards - trends
Humans
Hypoglycemic agents - therapeutic use
Mass Screening
Patient Education as Topic
Population Groups
Primary Prevention
Risk Reduction Behavior
Abstract
Youth-onset type 2 diabetes is a serious public health problem for Indigenous people throughout the world. This article reviews the epidemiology, disease burden, treatment, and challenges in achieving successful clinical management of this disorder in Indigenous youth. Screening criteria and the complications and comorbidities of type 2 diabetes are also reviewed.
PubMed ID
19962030 View in PubMed
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[Cost-effectiveness of continuous subcutaneous insulin infusion therapy for type 1 diabetes]

https://arctichealth.org/en/permalink/ahliterature96502
Source
Ugeskr Laeger. 2010 Jul 5;172(27):2020-5
Publication Type
Article
Date
Jul-5-2010
Author
Kirsten Nørgaard
Anna Sohlberg
Gordan Goodall
Author Affiliation
Hvidovre Hospital, Endokrinologisk Afdeling, Medtronic AB, Järfälla, Sverige. kirsten.noergaard@hvh.regionh.dk
Source
Ugeskr Laeger. 2010 Jul 5;172(27):2020-5
Date
Jul-5-2010
Language
Danish
Publication Type
Article
Keywords
Adult
Cohort Studies
Cost-Benefit Analysis
Diabetes Complications - diagnosis - etiology
Diabetes Mellitus, Type 2 - blood - drug therapy - economics
Female
Health Care Costs
Hemoglobin A, Glycosylated - analysis
Humans
Hypoglycemic Agents - administration & dosage
Infusions, Subcutaneous
Insulin - administration & dosage
Insulin Infusion Systems - economics
Life expectancy
Male
Prognosis
Quality-Adjusted Life Years
Treatment Outcome
Abstract
INTRODUCTION: This study's aim was to project the long-term clinical and economic outcomes of continuous subcutaneous insulin infusion (CSII) treatment compared to multiple daily injections (MDI) in type 1 diabetes patients in Denmark. MATERIAL AND METHODS: The CORE diabetes model was used to project life expectancy, quality-adjusted life expectancy, cumulative incidence of diabetes-related complications and costs over patient lifetimes. The simulated cohort was based upon a recent meta-analysis of CSII treatment from over 50 studies. Direct and indirect costs (human capital approach) from a healthcare payer perspective were accounted in year 2005 local currency. Outcomes were discounted according to recommendations and simulations performed over a 60 year time horizon. RESULTS: CSII treatment was associated with improved life expectancy, quality-adjusted life expectancy and reduced incidence of most diabetes-related complications compared to MDI. In the base case analysis, lifetime costs were higher for CSII than for MDI with incremental cost-effectiveness ratios in terms of cost per quality-adjusted life year gained within the range generally considered good value for money. Sensitivity analyses revealed that the findings were most sensitive to variation in assumptions regarding time horizon and hypoglycaemic event rate. CONCLUSION: CSII led to improved long-term clinical outcomes due to improved glycaemic control versus MDI. Evaluation of the economic impact of CSII treatment versus MDI demonstrated that it would be likely to represent good value for money by currently accepted standards.
PubMed ID
20594535 View in PubMed
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Diabetes care and health status of First Nations individuals with type 2 diabetes in Alberta.

https://arctichealth.org/en/permalink/ahliterature151531
Source
Can Fam Physician. 2009 Apr;55(4):386-93
Publication Type
Article
Date
Apr-2009
Author
Richard T Oster
Shainoor Virani
David Strong
Sandra Shade
Ellen L Toth
Author Affiliation
Department of Medicine, University of Alberta, 362C Heritage Medical Research Centre, Edmonton, Alberta. roster@ualberta.ca
Source
Can Fam Physician. 2009 Apr;55(4):386-93
Date
Apr-2009
Language
English
Publication Type
Article
Keywords
Adult
Age Distribution
Aged
Alberta - epidemiology
Attitude to Health - ethnology
Body mass index
Confidence Intervals
Diabetes Complications - diagnosis - ethnology - therapy
Diabetes Mellitus, Type 2 - diagnosis - drug therapy - ethnology
Female
Health Surveys
Humans
Hypoglycemic agents - therapeutic use
Incidence
Indians, North American - statistics & numerical data
Male
Mass Screening
Middle Aged
Mobile Health Units
Odds Ratio
Patient compliance
Prognosis
Severity of Illness Index
Sex Distribution
Abstract
To describe the state of diabetes care among Alberta First Nations individuals with diabetes living on reserves.
Survey and screening for diabetes-related complications.
Forty-three Alberta First Nations communities.
A total of 743 self-referred First Nations individuals with known diabetes.
Clinical measurements (glycated hemoglobin A(1c) levels, body mass index, waist circumference, total cholesterol, blood pressure, and the presence of kidney complications or proteinuria, retinopathy, and foot abnormalities), self-reported health services utilization, clinical history, and knowledge of and satisfaction with diabetes services.
Female participants tended to be more obese (P
Notes
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Comment In: Can Fam Physician. 2009 Apr;55(4):334-919366932
PubMed ID
19366950 View in PubMed
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Source
Diabetologia. 1986 Jan;29(1):1-9
Publication Type
Article
Date
Jan-1986
Author
D R Hadden
Source
Diabetologia. 1986 Jan;29(1):1-9
Date
Jan-1986
Language
English
Publication Type
Article
Keywords
Abnormalities - etiology - prevention & control
Animals
Blood glucose
Breast Feeding
Carbohydrate Metabolism
Denmark
Diabetic Nephropathies - therapy
Diabetic Retinopathy - therapy
Female
Great Britain
Humans
Hypoglycemia - diagnosis
Infant, Low Birth Weight
Infant, Newborn
Insulin - administration & dosage
Monitoring, Physiologic
Pregnancy
Pregnancy Complications
Pregnancy Trimester, Third
Pregnancy in Diabetics - complications - diagnosis - therapy
Prenatal care - trends
Rats
Time Factors
Ultrasonography
Abstract
The art of obstetrics is not a subject which is often discussed in the pages of Diabetologia. However, as the care of the diabetic mother and her offspring is rightly an interdisciplinary responsibility between obstetrician, diabetologist and neonatologist, it is important that each has a close understanding of the various problems. Dr. M.I. Drury (Dublin), speaking as an internist, raises a question on the optimum time and method of delivery of the baby; this has more than purely obstetrical implications. Drs. L. Mølsted-Pedersen (Copenhagen) and C. Kühl (Copenhagen and Klampenborg), obstetrician and internist from the longest-established joint obstetric/diabetic service in the world, present a Scandinavian view on the management of pregnancy. Both centres have distinguished records in the management of diabetic pregnancy. The different viewpoints in Denmark and in Ireland are clear - in Copenhagen, therapeutic abortion is practiced in a pregnancy at risk of severe congenital malformation; in Dublin it is not. Dr. Drury quotes a perinatal loss of 13 of 285 pregnancies (4.5%) in the past 5 years, but does not include the recognised spontaneous abortions which, on his overall figures, are about 10% of conceptions. Dr. Mølsted-Pedersen reports a perinatal loss of 3 of 201 infants (1.5%), excluding 17 spontaneous and 9 induced abortions. If these 9 aborted pregnancies, which were performed due to a risk of severe congenital malformation, were included as fatalities, the Copenhagen figure would be 12 of 210 (5.5%). Of course, we do not know if all those 9 fetuses were affected. The spontaneous abortion rate was 17 of 223 (8.0%).(ABSTRACT TRUNCATED AT 250 WORDS)
PubMed ID
3514340 View in PubMed
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[Diabetes mellitus--a dangerous treat to the mankind].

https://arctichealth.org/en/permalink/ahliterature124756
Source
Vestn Ross Akad Med Nauk. 2012;(1):7-13
Publication Type
Article
Date
2012
Author
I I Dedov
Source
Vestn Ross Akad Med Nauk. 2012;(1):7-13
Date
2012
Language
Russian
Publication Type
Article
Keywords
Consultants
Delivery of Health Care - organization & administration
Diabetes Complications - diagnosis - epidemiology - therapy
Diffusion of Innovation
Epidemiologic Methods
Humans
Monitoring, Physiologic - methods - standards
Patient Care Management - methods - organization & administration
Quality Improvement - organization & administration
Russia - epidemiology
World Health Organization
Abstract
According to the WHO and the UN definitions, diabetes mellitus is a non-infectious disease that has an epidemic spread rate, this has led to the UN 2006 resolution against diabetes mellitus. A special diabetologic service has been established in Russia which includes Federal and regional diabetes centres, endocrinologic clinics, equipped with modem diagnostic and treatment equipment for diabetes and its vascular complications handling. Planning of diabetologic service functioning is based on State diabetes mellitus register data, according to which nowadays in Russia 3 268 871 patients have been registered. This article contains data from control-and-epidemiological studies from various regions of Russia which have shown real spread of the disease. This article also contains information about innovative technologies of treatment of diabetes mellitus and its complications, international and national foreground studies, as well as discussion of diabetologic service development perspectives.
PubMed ID
22550704 View in PubMed
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33 records – page 1 of 4.