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Atopic and non-atopic asthma in a farming and a general population.

https://arctichealth.org/en/permalink/ahliterature15135
Source
Am J Ind Med. 2004 Oct;46(4):396-9
Publication Type
Article
Date
Oct-2004
Author
Wijnand Eduard
Ernst Omenaas
Per Sigvald Bakke
Jeroen Douwes
Dick Heederik
Author Affiliation
National Institute of Occupational Health, Oslo, Norway. Winjuad.Eduard@stami.no
Source
Am J Ind Med. 2004 Oct;46(4):396-9
Date
Oct-2004
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Agricultural Workers' Diseases - epidemiology - etiology - immunology
Asthma - epidemiology - etiology - immunology
Comparative Study
Dermatitis, Atopic - epidemiology - etiology - immunology
Endotoxins - immunology
Environmental Exposure - adverse effects
Female
Humans
Male
Middle Aged
Norway - epidemiology
Occupational Exposure - adverse effects
Prevalence
Questionnaires
Rural Population
Spores, Fungal - immunology
Abstract
BACKGROUND: In a previous study inverse associations between asthma and exposure to fungal spores and endotoxins in atopic farmers and positive associations with the same factors in non-atopic farmers were documented. No external reference population had been included. We, therefore, compared this farming population with the general population from an adjacent region. METHODS: Random samples of a farming (n=2,106) and a rural (n=351) and urban (n=727) general population were selected. Atopy was assessed by serum IgE and asthma by questionnaires. RESULTS: The asthma prevalence was 4.0% among farmers, 5.7% in the rural, and 7.6% in the urban population. Atopy was similar (9-10%). Most asthmatics were not atopic, 67-75%. Farmers had asthma less often than the general population OR 0.52 (95% CI 0.36-0.75); both atopic (OR 0.33 (95% CI 0.15-0.69)) and non-atopic asthma (OR 0.60 (95% CI 0.39-0.93)). CONCLUSION: This may indicate a protective effect of the farm environment on asthma but a healthy worker effect may also play a role.
PubMed ID
15376208 View in PubMed
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