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Clinical results of 40 years of paediatric keratoplasty in a single university eye clinic.

https://arctichealth.org/en/permalink/ahliterature259177
Source
Acta Ophthalmol. 2014 Jun;92(4):370-7
Publication Type
Article
Date
Jun-2014
Author
Maria Hovlykke
Jesper Hjortdal
Niels Ehlers
Kim Nielsen
Source
Acta Ophthalmol. 2014 Jun;92(4):370-7
Date
Jun-2014
Language
English
Publication Type
Article
Keywords
Adolescent
Age Distribution
Child
Child, Preschool
Corneal Diseases - diagnosis - epidemiology - surgery
Denmark - epidemiology
Female
Graft Survival - physiology
Humans
Infant
Infant, Newborn
Keratoplasty, Penetrating
Male
Postoperative Complications
Questionnaires
Reoperation
Risk factors
Visual Acuity - physiology
Abstract
To evaluate indications for paediatric keratoplasty in recipients aged =16 years and assess long-term clinical outcome.
Recipients were identified from records of the Danish Cornea Bank. Data were collected from patient journals, clinical follow-up examinations and questionnaires and stratified into pre-, peri- and postoperative variables. Diagnoses were classified into acquired traumatic, acquired nontraumatic and congenital groups. Recipients were divided into groups of
PubMed ID
23879323 View in PubMed
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Correlation of clinical and pathologic diagnoses of corneal disease in penetrating keratoplasties in Vancouver: a 10-year review.

https://arctichealth.org/en/permalink/ahliterature126996
Source
Can J Ophthalmol. 2012 Feb;47(1):5-10
Publication Type
Article
Date
Feb-2012
Author
Claire A Sheldon
J Martin McCarthy
Valerie A White
Author Affiliation
Department of Ophthalmology & Visual Sciences, Vancouver General Hospital and University of British Columbia, Vancouver, BC. claires@interchange.ubc.ca
Source
Can J Ophthalmol. 2012 Feb;47(1):5-10
Date
Feb-2012
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
British Columbia - epidemiology
Child
Child, Preschool
Cornea - pathology
Corneal Diseases - diagnosis - epidemiology - surgery
Female
Humans
Infant
Keratoplasty, Penetrating - statistics & numerical data
Male
Middle Aged
Reoperation
Retrospective Studies
Young Adult
Abstract
The objectives of the present study were: (i) to examine the leading clinical indications and pathologic diagnoses of penetrating keratoplasties in Vancouver, BC; and (ii) to evaluate the correlation between the clinical and pathologic diagnoses.
Retrospective chart review of all pathologic records of corneal tissue submitted to the Department of Pathology & Laboratory Medicine, Vancouver General Hospital, during an 11-year period.
For each penetrating keratoplasty, information regarding the clinical indication and pathologic features identified on histopathologic analysis was compiled.
The top 5 clinical indications for transplant were failed graft (21%); bullous keratopathy (20%); keratoconus (17%); scarring, with or without inflammation (14%); and Fuchs dystrophy (11%). The top 5 pathologic diagnoses corresponded to these clinical diagnoses. In the majority of cases, there was agreement between clinical and pathologic diagnoses; however, in 6% of records, the clinical and pathologic diagnoses did not correlate. This situation occurred most often when considering grafts with clinical diagnoses of bullous keratopathy, Fuchs dystrophy, or keratoconus. A review of the grafts with infectious keratitis illustrated the potential for histopathologic evaluation of corneal buttons to identify unsuspected infectious agents.
Routine histopathologic evaluation of penetrating keratoplasty clarifies the clinical diagnosis in a proportion of cases and aids in identifying infectious agents.
PubMed ID
22333843 View in PubMed
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Prevalence and risk factors for cornea guttata in the Reykjavik Eye Study.

https://arctichealth.org/en/permalink/ahliterature50515
Source
Ophthalmology. 2006 Apr;113(4):565-9
Publication Type
Article
Date
Apr-2006
Author
Gunnar M Zoega
Aya Fujisawa
Hiroshi Sasaki
Akiko Kubota
Kazuyuki Sasaki
Kazuko Kitagawa
Fridbert Jonasson
Author Affiliation
Department of Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland.
Source
Ophthalmology. 2006 Apr;113(4):565-9
Date
Apr-2006
Language
English
Publication Type
Article
Keywords
Age Distribution
Aged
Aged, 80 and over
Cell Count
Corneal Diseases - diagnosis - epidemiology
Cross-Sectional Studies
Descemet Membrane - pathology
Endothelium, Corneal - pathology
Female
Humans
Iceland - epidemiology
Male
Middle Aged
Prevalence
Research Support, Non-U.S. Gov't
Risk factors
Sex Distribution
Abstract
PURPOSE: To establish the age- and gender-specific prevalence of cornea guttata (CG) in citizens of Reykjavik, Iceland, 55 years and older. DESIGN: Cross-sectional, random, population-based study. PARTICIPANTS: The 774 participants were those participating in the second examination of the Reykjavik Eye Study. At baseline, we had a response rate of 75.8%, and at the 5-year follow-up, 88% of the survivors participated. METHODS: We used slit-lamp and non-contact specular microscopy and endothelial specular photography as well as computer-assisted morphometry. We used a standardized grading system for CG. MAIN OUTCOME MEASURES: Diagnosis of primary central CG. RESULTS: The prevalence of CG is 11% for females and 7% for males both for right eyes and left eyes. Higher weight and higher body mass index are found to be associated with decreased risk of CG. Having smoked more than 20 pack-years increased the risk of CG more than 2-fold (P
PubMed ID
16581419 View in PubMed
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Prevalence of and risk factors for cornea guttata in a population-based study in a southwestern island of Japan: the Kumejima study.

https://arctichealth.org/en/permalink/ahliterature136178
Source
Arch Ophthalmol. 2011 Mar;129(3):332-6
Publication Type
Article
Date
Mar-2011
Author
Akiko Higa
Hiroshi Sakai
Shoichi Sawaguchi
Aiko Iwase
Atsuo Tomidokoro
Shiro Amano
Makoto Araie
Author Affiliation
Department of Ophthalmology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Source
Arch Ophthalmol. 2011 Mar;129(3):332-6
Date
Mar-2011
Language
English
Publication Type
Article
Keywords
Adult
Age Distribution
Aged
Aged, 80 and over
Corneal Diseases - diagnosis - epidemiology
Cross-Sectional Studies
Descemet Membrane - pathology
Endothelium, Corneal - pathology
Female
Humans
Japan - epidemiology
Male
Middle Aged
Prevalence
Questionnaires
Risk factors
Rural Population - statistics & numerical data
Sex Distribution
Abstract
To examine the prevalence of and risk factors for cornea guttata in a rural southwestern island of Japan.
Cross-sectional, population-based study. All residents of Kumejima Island, Japan, located in southwestern Japan (eastern longitude, 126° 48'; northern latitude, 26° 20'), 40 years or older were asked to undergo a comprehensive questionnaire and ocular examination, including noncontact specular microscopy of corneal endothelial cells. Of the 4632 residents, 3762 (81.2%) underwent the examination. The presence of guttata was determined when round or oval dark areas were observed in the specular microscopy images. Cornea guttata was graded from 0 to 4 depending on the total area of dark spots observed on the specular microscopy images. Diagnosis of primary cornea guttata was the main outcome measure.
Of the 3060 eligible residents, 124 (4.1%; 95% confidence interval, 3.4%-4.8%) had cornea guttata in at least 1 eye. Logistic regression analysis with adjustment for age and/or sex indicated that older age, female sex, and thinner central corneal thickness were associated with an increased risk of cornea guttata.
The prevalence of cornea guttata is 4.1% among residents 40 years or older in Kumejima by specular microscopic criteria only, which is lower than the prevalence reported in the Reykjavik, Iceland, study. A higher prevalence may have been determined if slitlamp biomicroscopy findings had been included. Older age, female sex, and a thinner cornea were independently associated with a higher risk of cornea guttata.
PubMed ID
21402991 View in PubMed
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Reykjavik Eye Study and cornea guttata.

https://arctichealth.org/en/permalink/ahliterature166161
Source
Ophthalmology. 2006 Dec;113(12):2374-5; author reply 2375
Publication Type
Article
Date
Dec-2006
Author
Arif O Khan
Source
Ophthalmology. 2006 Dec;113(12):2374-5; author reply 2375
Date
Dec-2006
Language
English
Publication Type
Article
Keywords
Corneal Diseases - diagnosis - epidemiology
Descemet Membrane - pathology
Endothelium, Corneal - pathology
Humans
Iceland - epidemiology
Prevalence
Risk factors
Sex Distribution
Terminology as Topic
Notes
Comment On: Ophthalmology. 2006 Apr;113(4):565-916581419
PubMed ID
17157145 View in PubMed
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