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Cumulated time with low bispectral index values is not related to the risk of new cancer or death within 5 years after surgery in patients with previous or prevailing malignancy.

https://arctichealth.org/en/permalink/ahliterature104671
Source
Anesth Analg. 2014 Apr;118(4):782-7
Publication Type
Article
Date
Apr-2014
Author
Maj-Lis Lindholm
Lars Brudin
Rolf H Sandin
Author Affiliation
From the Departments for *Anesthesia and Intensive Care and †Clinical Physiology, Lanssjukhuset, Kalmar; Department of Medicine and Health Sciences, University Hospital Linköping, Linköping; and ‡Section for Anesthesiology and Intensive Care Medicine, Karolinska Institutet, Stockholm, Sweden.
Source
Anesth Analg. 2014 Apr;118(4):782-7
Date
Apr-2014
Language
English
Publication Type
Article
Keywords
Adult
Aged
Anesthesia - methods
Anesthesia, General
Anesthetics, Inhalation
Cohort Studies
Consciousness Monitors
Female
Humans
Kaplan-Meier Estimate
Male
Methyl Ethers
Middle Aged
Neoplasms - epidemiology - mortality - surgery
Proportional Hazards Models
Prospective Studies
Registries
Risk
Survival Analysis
Sweden - epidemiology
Treatment Outcome
Abstract
Preclinical data indicate that anesthesia and surgery may promote cancer growth. We previously found no increased risk of malignant disease within 5 years regarding duration of general anesthesia (TANESTH) and time with Bispectral Index (BIS) under 45 (TBIS
PubMed ID
24651233 View in PubMed
Less detail

Exploring the validity of the bispectral index, the Critical-Care Pain Observation Tool and vital signs for the detection of pain in sedated and mechanically ventilated critically ill adults: a pilot study.

https://arctichealth.org/en/permalink/ahliterature138525
Source
Intensive Crit Care Nurs. 2011 Feb;27(1):46-52
Publication Type
Article
Date
Feb-2011
Author
Céline Gélinas
Yannick Tousignant-Laflamme
Andréanne Tanguay
Patricia Bourgault
Author Affiliation
McGill University, School of Nursing, 3506, University Street, Wilson Hall, Montréal, Qc, H3A 2A7 Canada. celine.gelinas@mcgill.ca
Source
Intensive Crit Care Nurs. 2011 Feb;27(1):46-52
Date
Feb-2011
Language
English
Publication Type
Article
Keywords
Adult
Aged
Conscious Sedation - adverse effects - nursing
Consciousness Monitors
Critical Care - methods
Female
Humans
Male
Middle Aged
Monitoring, Physiologic - instrumentation - methods - nursing
Nursing Assessment - methods
Nursing Evaluation Research
Pain - diagnosis - etiology
Pain Measurement - instrumentation - methods - nursing
Pilot Projects
Quebec
Respiration, Artificial - adverse effects - nursing
Sensitivity and specificity
Severity of Illness Index
Vital Signs
Abstract
This pilot study aimed to explore the validity of the bispectral (BIS) index, the Critical-Care Pain Observation Tool (CPOT) score, and vital signs (mean arterial pressure, heart rate) during rest and painful procedures in sedated and mechanically ventilated ICU adults. A convenience sample of nine patients with various diagnoses participated in this observational repeated measures study. Patients were observed during 2 minute periods at rest (baseline), and during procedures known to be painful: turning and endotracheal suctioning. Both the BIS index and the CPOT score were found to increase when patients were exposed to procedures compared with rest, and were found to be more sensitive to procedures compared with vital signs. Indeed, vital signs remained quite stable during procedures in this sample. Results from this study support the recommendation that behavioural indicators (i.e. in this case, the use of a behavioural pain scale called the CPOT) be used for the detection of pain in nonverbal ICU patients. However, in some situations (e.g. deep sedation, use of blocking agents), behavioural indicators may no longer be observable, and all that is left are physiologic signs. The BIS seems to be an interesting technique and further research is required in order to establish if it could be used to guide clinicians for the detection of pain in this vulnerable population.
PubMed ID
21169020 View in PubMed
Less detail

Malignant disease within 5 years after surgery in relation to duration of sevoflurane anesthesia and time with bispectral index under 45.

https://arctichealth.org/en/permalink/ahliterature134341
Source
Anesth Analg. 2011 Oct;113(4):778-83
Publication Type
Article
Date
Oct-2011
Author
Maj-Lis Lindholm
Fredrik Granath
Lars I Eriksson
Rolf Sandin
Author Affiliation
Department of Physiology and Pharmacology, Section of Anesthesiology and Intensive Care Medicine, Karolinska Institutet, Stockholm, Sweden. majlisl@ltkalmar.se
Source
Anesth Analg. 2011 Oct;113(4):778-83
Date
Oct-2011
Language
English
Publication Type
Article
Keywords
Adult
Aged
Anesthetics, Inhalation - administration & dosage - adverse effects
Consciousness Monitors
Female
Humans
Incidence
Kaplan-Meier Estimate
Male
Methyl Ethers - administration & dosage - adverse effects
Middle Aged
Monitoring, Intraoperative - instrumentation
Neoplasms - epidemiology - etiology
Predictive value of tests
Proportional Hazards Models
Registries
Risk assessment
Risk factors
Surgical Procedures, Operative - adverse effects
Sweden - epidemiology
Time Factors
Abstract
Surgery, general anesthesia, and related events have been implicated to promote cancer proliferation. We investigated the incidence of cancer within 5 years after surgery in relation to duration of anesthesia (T(ANESTH)) and also by time with bispectral index (BIS) under 45 (T(BIS
Notes
Comment In: Anesth Analg. 2011 Oct;113(4):681-321948276
PubMed ID
21596878 View in PubMed
Less detail