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184 records – page 1 of 19.

[Actions of the tobacco industry and Swedish physicians]

https://arctichealth.org/en/permalink/ahliterature69051
Source
Lakartidningen. 2002 Jun 27;99(26-27):2974
Publication Type
Article
Date
Jun-27-2002
Author
John Wahren
Source
Lakartidningen. 2002 Jun 27;99(26-27):2974
Date
Jun-27-2002
Language
Swedish
Publication Type
Article
Keywords
Conflict of Interest
Humans
Physician's Role
Sweden
Tobacco Industry
Tobacco Smoke Pollution - adverse effects - prevention & control
PubMed ID
12170694 View in PubMed
Less detail

Actors involved in the regulation of clinical research: comparison of Finland to England, Canada, and the USA.

https://arctichealth.org/en/permalink/ahliterature269574
Source
Health Res Policy Syst. 2015;13:20
Publication Type
Article
Date
2015
Author
Elina Hemminki
Source
Health Res Policy Syst. 2015;13:20
Date
2015
Language
English
Publication Type
Article
Keywords
Administrative Personnel
Biomedical Research - legislation & jurisprudence
Canada
Conflict of Interest
Drug and Narcotic Control
England
Ethics Committees, Research
Finland
Government Regulation
Interviews as Topic
Qualitative Research
United States
Abstract
The relevance and quantity of clinical research has caused concern and regulation is claimed to hinder clinical research. This paper compares clinical research regulations in Finland to those of England, Canada, and the USA around 2010-2011.
Several approaches and data sources were used, including semi- or unstructured interviews of experts. For the analysis, a theoretical framework was made, data from various sources was synthesized, and features of the systems were simplified and classified. The various specific names and terms used in the data were changed into general ones.
Common structures for the regulation existed in all four countries, but the details and scope varied. The research regulated within the main system was determined by research type (Finland), the financer of the health system (England), or research site (Canada, USA). Only Finland had specific legislation on medical research. The overriding impression of the regulatory systems was one of complexity. All countries had extra regulation for drug research. The types of drug research covered varied from trials with unlicensed (new) products or new indications (USA and Canada), to all types of interventional drug research (England), where 'interventional' was interpreted broadly (Finland). The complexity of regulations had led to the creation of various big and small businesses to help researchers and sponsors. There was notable variation in the role played by the public research funder. The role played by health care was difficult to study and seemed to involve varying interests as researchers were also health care employees. Research ethics committees were important and their tasks also included aspects other than ethics.
This study revealed that a comparison between countries can provide useful insights into the distinctive aspects of each country's system, as well as identifying common features that require international action.
Notes
Cites: IRB. 2007 Mar-Apr;29(2):7-1317847609
Cites: N Engl J Med. 2011 Sep 22;365(12):1145-5021787202
Cites: Milbank Q. 2011 Dec;89(4):599-62722188349
Cites: Clin Pharmacol Ther. 2012 Mar;91(3):535-4122318614
Cites: Trials. 2012;13:2722452964
Cites: Trials. 2012;13:5322540886
Cites: Int J Risk Saf Med. 2012;24(4):233-4223135338
Cites: Health Res Policy Syst. 2013;11:1723680289
Cites: Lancet. 2014 Jan 11;383(9912):176-8524411646
Cites: Health Res Policy Syst. 2014;12:1524666735
Cites: J Med Ethics. 2014 Jun;40(6):409-1323665856
PubMed ID
25888977 View in PubMed
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Alberta pharmacists may get prescribing powers.

https://arctichealth.org/en/permalink/ahliterature167705
Source
CMAJ. 2006 Aug 29;175(5):463-4
Publication Type
Article
Date
Aug-29-2006
Author
Alicia Priest
Source
CMAJ. 2006 Aug 29;175(5):463-4
Date
Aug-29-2006
Language
English
Publication Type
Article
Keywords
Alberta
Conflict of Interest
Drug Prescriptions
Health Policy
Humans
Legislation, Drug
Pharmacists
Notes
Comment In: CMAJ. 2007 Jan 2;176(1):6717200400
PubMed ID
16940256 View in PubMed
Less detail

An analysis of the clinical development of drugs in Norway for the years 2000 and 2004: the influence of the pharmaceutical industry.

https://arctichealth.org/en/permalink/ahliterature162102
Source
Eur J Clin Pharmacol. 2007 Oct;63(10):909-12
Publication Type
Article
Date
Oct-2007
Author
Finn O Winther
Ola P Hole
Sigurd Nitter-Hauge
Author Affiliation
Faculty Division Rikshospitalet, University of Oslo, 0027, Oslo, Norway. finnow@ulrik.uio.no
Source
Eur J Clin Pharmacol. 2007 Oct;63(10):909-12
Date
Oct-2007
Language
English
Publication Type
Article
Keywords
Academies and Institutes - economics - statistics & numerical data
Bias (epidemiology)
Biomedical Research - economics - ethics - statistics & numerical data
Clinical Trials as Topic - economics - ethics - statistics & numerical data
Conflict of Interest
Drug Industry - economics - ethics - statistics & numerical data
Hospitals, Private - economics - statistics & numerical data
Hospitals, Public - economics - statistics & numerical data
Humans
Norway - epidemiology
Research Support as Topic - ethics - statistics & numerical data
Time Factors
Abstract
Little has been published either concerning the total number of research projects in connection with clinical development of drugs or the number of projects financially supported by the industry.
From the archives of the five regional Norwegian Research Ethical Committees (REC), all research projects in connection with clinical development of drugs for the years 2000 and 2004 were analysed with the intention of finding the number of projects financially supported by the industry, the type of research institution, the industrial company, the topic of the research as classified in the international Anatomic Therapeutic Classification system (ATC), the research phase and the approval status of the drug by the Norwegian Medicines Agency (NMA).
The total number of research projects for the clinical development of drugs for the years 2000 and 2004 was 489, and 75.7% were financially supported by the industry. More than two-thirds of the projects were done in academic institutions and about one-third were equally divided between public health hospitals and private health service/hospitals. Eight of the 88 drug companies involved were among the world's largest and supported 38% of the projects. Fifty-nine percent of all the projects were within four therapeutic groups: antineoplastic/immunomodulating agents, nervous system, cardiovascular system and alimentary tract/metabolism. The distribution of research phases was as follows: phase I 1.2%, phase II 16.4%, phase III 26.6% and phase IV 55.8%. In the phase IV drug trials, drugs had been approved for sale by the NMA.
The share of research projects related to the development of drugs supported by the industry is high. Research independent of the industry is of importance to avoid bias and selective publications and to prevent research as a means of marketing. Independent research should be encouraged and financially supported by sources with no connection to the drug industry.
PubMed ID
17673994 View in PubMed
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The Andrew Pattullo lecture. Healthy populations or healthy institutions: the dilemma of health care management.

https://arctichealth.org/en/permalink/ahliterature212676
Source
J Health Adm Educ. 1995;13(3):453-72
Publication Type
Article
Date
1995

An ethicist's commentary on avoiding impropriety in corporate sponsorship of conferences and journals.

https://arctichealth.org/en/permalink/ahliterature161505
Source
Can Vet J. 2007 Aug;48(8):792
Publication Type
Article
Date
Aug-2007

[Apropos the campaign material "It's not your fault"]

https://arctichealth.org/en/permalink/ahliterature30923
Source
Ugeskr Laeger. 2003 Apr 28;165(18):1895
Publication Type
Article
Date
Apr-28-2003
Author
Jannik Hilsted
Author Affiliation
Rigshospitalet.
Source
Ugeskr Laeger. 2003 Apr 28;165(18):1895
Date
Apr-28-2003
Language
Danish
Publication Type
Article
Keywords
Child
Conflict of Interest
Denmark
Drug Industry
Enuresis - prevention & control - psychology
Hospital Units - economics
Humans
Patient Education
PubMed ID
12772404 View in PubMed
Less detail

184 records – page 1 of 19.