Skip header and navigation

2 records – page 1 of 1.

The Norwegian dietary guidelines and colorectal cancer survival (CRC-NORDIET) study: a food-based multicentre randomized controlled trial.

https://arctichealth.org/en/permalink/ahliterature283837
Source
BMC Cancer. 2017 Jan 30;17(1):83
Publication Type
Article
Date
Jan-30-2017
Author
HB Henriksen
H. Ræder
SK Bøhn
I. Paur
AS Kværner
SÅ Billington
MT Eriksen
G. Wiedsvang
I. Erlund
A. Færden
MB Veierød
M. Zucknick
S. Smeland
R. Blomhoff
Source
BMC Cancer. 2017 Jan 30;17(1):83
Date
Jan-30-2017
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Colorectal Neoplasms - diet therapy - mortality - pathology
Disease-Free Survival
Female
Humans
Male
Middle Aged
Multicenter Studies as Topic
Neoplasm Recurrence, Local - mortality - prevention & control
Norway
Oxidative Stress
Randomized Controlled Trials as Topic
Research Design
Treatment Outcome
Abstract
Colorectal cancer survivors are not only at risk for recurrent disease but also at increased risk of comorbidities such as other cancers, cardiovascular disease, diabetes, hypertension and functional decline. In this trial, we aim at investigating whether a diet in accordance with the Norwegian food-based dietary guidelines and focusing at dampening inflammation and oxidative stress will improve long-term disease outcomes and survival in colorectal cancer patients.
This paper presents the study protocol of the Norwegian Dietary Guidelines and Colorectal Cancer Survival study. Men and women aged 50-80 years diagnosed with primary invasive colorectal cancer (Stage I-III) are invited to this randomized controlled, parallel two-arm trial 2-9 months after curative surgery. The intervention group (n?=?250) receives an intensive dietary intervention lasting for 12 months and a subsequent maintenance intervention for 14 years. The control group (n?=?250) receives no dietary intervention other than standard clinical care. Both groups are offered equal general advice of physical activity. Patients are followed-up at 6 months and 1, 3, 5, 7, 10 and 15 years after baseline. The study center is located at the Department of Nutrition, University of Oslo, and patients are recruited from two hospitals within the South-Eastern Norway Regional Health Authority. Primary outcomes are disease-free survival and overall survival. Secondary outcomes are time to recurrence, cardiovascular disease-free survival, compliance to the dietary recommendations and the effects of the intervention on new comorbidities, intermediate biomarkers, nutrition status, physical activity, physical function and quality of life.
The current study is designed to gain a better understanding of the role of a healthy diet aimed at dampening inflammation and oxidative stress on long-term disease outcomes and survival in colorectal cancer patients. Since previous research on the role of diet for colorectal cancer survivors is limited, the study may be of great importance for this cancer population.
ClinicalTrials.gov Identifier: NCT01570010 .
Notes
Cites: Rapid Commun Mass Spectrom. 2012 Mar 30;26(6):645-5222328218
Cites: Nutrients. 2015 Apr 09;7(4):2589-62125859884
Cites: J Hum Hypertens. 2013 Feb;27(2):126-3022258209
Cites: Cancer. 2014 May 1;120(9):1290-31424343171
Cites: J Nutr. 2011 Apr 1;141(4):639-4421346102
Cites: Free Radic Biol Med. 2002 Mar 1;32(5):386-9311864778
Cites: Scand J Soc Med. 1998 Dec;26(4):250-89868748
Cites: BMC Med. 2010 Sep 16;8:5420846424
Cites: Br J Cancer. 2011 Nov 8;105 Suppl 1:S52-7322048034
Cites: Nutr Cancer. 2010;62(6):841-820661833
Cites: J Am Geriatr Soc. 2010 Feb;58(2):234-4120370857
Cites: Am J Clin Nutr. 2012 Dec;96(6):1346-5323134880
Cites: BMJ. 1994 Mar 19;308(6931):763-67908238
Cites: Br J Nutr. 2011 May;105(10):1530-821272408
Cites: Curr Opin Oncol. 2001 Jan;13(1):63-911148689
Cites: Int J Cancer. 2013 May 1;132(9):2157-6323015513
Cites: J Nutr. 2007 Jan;137(1 Suppl):243S-248S17182834
Cites: J Natl Cancer Inst. 2007 Jul 4;99(13):998-100317596575
Cites: J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):940-82571680
Cites: Science. 1998 May 15;280(5366):1036-79616081
Cites: Eur J Cancer. 2013 Mar;49(4):769-8123122780
Cites: Am J Med. 2007 Jul;120(7):598-60317602933
Cites: J Nutr Biochem. 2016 Jan;27:153-6326419686
Cites: J Nutr. 2003 May;133(5):1286-9012730411
Cites: J Psychosom Res. 1993;37(2):147-538463991
Cites: J Diabetes Sci Technol. 2013 Sep 01;7(5):1386-9924124968
Cites: Clin Sci (Lond). 1983 Jun;64(6):629-356601560
Cites: Cancer Prev Res (Phila). 2012 Jan;5(1):98-10821982875
Cites: Am J Clin Nutr. 2006 May;83(5):1039-4616685044
Cites: Cancer Prev Res (Phila). 2010 May;3(5):653-6320424131
Cites: Cell. 2011 Mar 4;144(5):646-7421376230
Cites: PLoS One. 2014 Dec 15;9(12 ):e11537725506700
Cites: Cancer Epidemiol Biomarkers Prev. 2002 May;11(5):459-6612010860
Cites: Curr Opin Clin Nutr Metab Care. 2014 Jan;17(1):40-424241129
Cites: Eur J Clin Nutr. 2001 Nov;55(11):1028-3311641754
Cites: Am J Clin Nutr. 2015 Mar;101(3):558-6925733641
Cites: Postgrad Med J. 2010 Feb;86(1012):73-820145054
Cites: Appl Physiol Nutr Metab. 2008 Oct;33(5):997-100618923576
Cites: Gastroenterology. 2010 Jun;138(6):2088-10020420948
Cites: Int J Cancer. 2014 Mar 1;134(5):1156-6523959920
Cites: Mech Ageing Dev. 2014 Mar-Apr;136-137:1-224472370
Cites: Nat Genet. 2006 Jul;38(7):787-9316804544
Cites: BMC Public Health. 2014 Jan 16;14 :4524433390
Cites: Nutr J. 2010 Jan 22;9:320096093
Cites: Lancet. 2014 Apr 26;383(9927):1490-50224225001
Cites: Br J Cancer. 2012 Mar 27;106(7):1353-6022353805
Cites: World J Gastroenterol. 2009 Dec 7;15(45):5706-1119960568
Cites: Cancer. 2014 Sep 1;120(17):2665-7224816611
Cites: Am J Clin Nutr. 2007 Jun;85(6):1606-1417556700
Cites: Nutr Cancer. 2006;54(1):94-10116800777
Cites: Cancer Causes Control. 2014 May;25(5):541-5224557428
Cites: Neurogastroenterol Motil. 2014 Aug;26(8):1155-6224888394
Cites: Am J Clin Nutr. 2013 May;97(5):1107-2023553166
Cites: Cell Biochem Funct. 2011 Jan-Feb;29(1):36-4221264888
Cites: BMC Cancer. 2011 Oct 11;11:43821989154
Cites: Nutr J. 2010 Sep 15;9:3720843361
Cites: J Natl Cancer Inst. 2004 Sep 1;96(17):1322-3015339970
Cites: JAMA. 2007 Aug 15;298(7):754-6417699009
Cites: Ann Behav Med. 2009 Oct;38(2):71-8520012809
Cites: Nutr Res. 2013 Oct;33(10):817-3024074740
Cites: BMJ Open. 2013 Feb 07;3(2):null23396503
Cites: J Nutr. 2007 Aug;137(8):1951-417634269
Cites: Eur J Clin Nutr. 2010 Jan;64(1):2-519935820
Cites: Br J Nutr. 2011 Aug;106(4):557-7121806852
Cites: J Clin Oncol. 2005 Aug 20;23(24):5814-3016043830
Cites: Am J Clin Nutr. 2006 Jul;84(1):95-13516825686
Cites: Mol Nutr Food Res. 2011 Feb;55(2):185-9720827676
Cites: Nutr Cancer. 2015;67(2):305-1525664890
Cites: J Natl Cancer Inst. 2013 Dec 4;105(23):1821-3224151326
Cites: Lancet. 2000 Sep 16;356(9234):968-7411041397
Cites: Ann Epidemiol. 1996 Sep;6(5):399-4128915471
Cites: Food Chem Toxicol. 2008 Apr;46(4):1288-9717980947
Cites: J Neurol Neurosurg Psychiatry. 1991 Feb;54(2):153-82019842
Cites: Science. 2013 Mar 29;339(6127):1546-5823539594
Cites: Nutrition. 1996 Jan;12(1 Suppl):S15-98850213
Cites: Eur J Clin Nutr. 2003 Jan;57(1):138-4212548308
Cites: Free Radic Biol Med. 2010 May 1;48(9):1218-2720176103
Cites: JAMA. 2009 May 13;301(18):1883-9119436015
Cites: Eur J Nutr. 2010 Sep;49(6):345-5520119859
Cites: Ann Oncol. 2014 Jul;25(7):1293-31124644304
Cites: Br J Nutr. 2006 Nov;96 Suppl 2:S52-6017125534
Cites: Ann Intern Med. 2010 Jun 1;152(11):726-3220335313
Cites: J Nutr. 2003 Jul;133(7):2137-4012840168
Cites: J Nutr. 2002 Mar;132(3):461-7111880572
Cites: N Engl J Med. 2004 Jun 3;350(23):2343-5115175436
Cites: N Engl J Med. 2003 Jun 26;348(26):2599-60812826634
Cites: Clin Cancer Res. 2013 Nov 1;19(21):6006-1924025712
Cites: J Nutr. 2004 Mar;134(3):562-714988447
Cites: Nutr J. 2011 May 18;10:5421586177
PubMed ID
28137255 View in PubMed
Less detail

Whole grain intake and survival among Scandinavian colorectal cancer patients.

https://arctichealth.org/en/permalink/ahliterature105978
Source
Nutr Cancer. 2014;66(1):6-13
Publication Type
Article
Date
2014
Author
Guri Skeie
Tonje Braaten
Anja Olsen
Cecilie Kyrø
Anne Tjønneland
Lena Maria Nilsson
Rikard Landberg
Eiliv Lund
Author Affiliation
a Department of Community Medicine , University of Tromsø , Tromsø , Norway.
Source
Nutr Cancer. 2014;66(1):6-13
Date
2014
Language
English
Publication Type
Article
Keywords
Aged
Cereals
Colorectal Neoplasms - diet therapy
Diet
Dietary Fiber - administration & dosage
Female
Food Habits
Humans
Life Style
Male
Middle Aged
Proportional Hazards Models
Prospective Studies
Risk factors
Scandinavia
Abstract
To our knowledge, no studies of associations between intake of whole grain (WHG) and survival of colorectal cancer have been published, despite evidence that dietary fiber, and to some extent WHG, are associated with lower risk of colorectal cancer. Scandinavia is an area where the WHG consumption traditionally is high. We performed a case-only (N = 1119) study in the Scandinavian HELGA cohort of pre-diagnosis WHG intake (total WHG, WHG wheat, WHG rye, and WHG oats) and survival of colorectal cancer. Cox regression analyses were used to study the associations, both in categorical and continuous models, stratified by location (proximal, distal, rectum) and country. No evidence of an association was found, neither for total WHG intake (hazard ratio = 1.32, 95% confidence interval: 0.88-1.97 lowest vs. highest tertile, adjusted for age at diagnosis, metastasis status, smoking, folate, margarine, and energy), nor for specific grains. Prediagnosis consumption of WHG does not seem to improve survival of colorectal cancer in subjects diagnosed within this prospective population-based Scandinavian cohort.
PubMed ID
24274588 View in PubMed
Less detail