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Assessment of endometrial and ovarian characteristics using three dimensional power Doppler ultrasound to predict response in frozen embryo transfer cycles.

https://arctichealth.org/en/permalink/ahliterature98513
Source
Reprod Biol Endocrinol. 2009;7:151
Publication Type
Article
Date
2009
Author
Tamara Zácková
Ilkka Y Järvelä
Juha S Tapanainen
Jaroslav Feyereisl
Author Affiliation
Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland. tamara.zackova@centrum.cz
Source
Reprod Biol Endocrinol. 2009;7:151
Date
2009
Language
English
Publication Type
Article
Keywords
Adult
Chorionic Gonadotropin - blood
Cryopreservation
Embryo Transfer - methods
Endometrium - metabolism - physiology - ultrasonography
Estradiol - blood
Female
Fertilization in Vitro
Humans
Imaging, Three-Dimensional
Infertility - therapy
Ovary - metabolism - physiology - ultrasonography
Predictive value of tests
Pregnancy
Progesterone - blood
Sperm Injections, Intracytoplasmic
Treatment Outcome
Ultrasonography, Doppler
Vagina - ultrasonography
Abstract
OBJECTIVE: To evaluate whether endometrial or ovarian parameters as measured using 3D power Doppler ultrasound would predict the outcome in frozen embryo transfer (FET) cycles. METHODS: Thirty women with no known gynecological pathology undergoing FET were recruited. The FET was carried out in the natural menstrual cycle 3-4 days after the first positive LH test result. Blood samples for hormonal analysis were collected, and three-dimensional (3D) ultrasonographic examination was performed on the day of the FET and repeated with analysis of the total hCG one week later. RESULTS: The demographic, clinical, and embryological characteristics were similar between the pregnant (15/30) and nonpregnant groups (15/30). There were no differences between the groups in endometrial/subendometrial thickness, volume, or vascularization index (VI). The endometrial triple-line pattern was more often present in the pregnant group on the day of the FET (93.3% vs. 40.0%, 95% CI 25.5-81.2%). No differences in the ovaries were observed on the day of the FET. At the second visit, the triple-line pattern was still more often present in those patients who had conceived (91.7% vs. 42.9%, 95% CI 18.5-79.1%), and their corpus luteum was more active as judged by the rise in 17-hydroxyprogesterone and estradiol levels. No differences were observed in the dominant ovarian vasculature. CONCLUSIONS: According to our results, measurement of power Doppler indices using 3D ultrasound on the day of the FET does not provide any additional information concerning the outcome of the cycle. The existence of the triple-line pattern on the day of the FET seems to be a prognostic sign of a prosperous outcome after FET. The dominant ovary in the pregnant group seems to be already activated one week after the FET.
PubMed ID
20035622 View in PubMed
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Biochemical markers for testicular germ-cell tumors in relation to histology and stage: some experiences from the Danish testicular cancer (DATECA) Study from 1976 through 1981.

https://arctichealth.org/en/permalink/ahliterature27000
Source
Ann N Y Acad Sci. 1983;417:390-9
Publication Type
Article
Date
1983
Author
B. Nørgaard-Pedersen
H. Schultz
J. Arends
H. Brincker
G K Jacobsen
B. Lindeløv
M. Rørth
I L Svennekjaer
Source
Ann N Y Acad Sci. 1983;417:390-9
Date
1983
Language
English
Publication Type
Article
Keywords
Alkaline Phosphatase - analysis
Chorionic Gonadotropin - blood
Dysgerminoma - mortality - pathology
Epidemiologic Methods
Humans
Male
Neoplasm Staging
Research Support, Non-U.S. Gov't
Testicular Neoplasms - mortality - pathology
alpha-Fetoproteins - analysis
Abstract
The DATECA Project was started in January 1976 and includes all patients with testicular cancer in Denmark. During the first 6 years, 1246 patients entered the joint protocol for histology, staging, management, and clinical use of tumor markers. Only 746 DATECA patients fulfilled the claims for being ideally monitored with preoperative as well as postoperative serologic marker determinations. The overall prevalence of marker positivity, that is, elevated preoperative values of alpha-fetoprotein (AFP) and/or human chorionic gonadotrophin (HCG) was 8% for patients with seminoma and 63% for patients with nonseminomatous disease. The prevalence of increased marker concentration in serum was correlated to stage (higher prevalence in higher stages) and to prognosis (marker-negative patients had a better prognosis than did marker-positive patients). An increased concentration of AFP or HCG was correlated with the presence of a primary endodermal sinus tumor and choriocarcinoma component, respectively.
PubMed ID
6200044 View in PubMed
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Canadian Society of Clinical Chemists position paper: standardization of selected polypeptide hormone measurements.

https://arctichealth.org/en/permalink/ahliterature222637
Source
Clin Biochem. 1992 Dec;25(6):415-24
Publication Type
Article
Date
Dec-1992
Source
Clin Biochem. 1992 Dec;25(6):415-24
Date
Dec-1992
Language
English
Publication Type
Article
Keywords
Calibration
Canada
Chorionic Gonadotropin - blood - chemistry
Follicle Stimulating Hormone - blood - chemistry
Growth Hormone - blood - chemistry
Hormones - blood - chemistry
Humans
Immunoassay - standards
Luteinizing Hormone - blood - chemistry
Pituitary Hormones, Anterior - blood - chemistry
Prolactin - blood - chemistry
Reference Values
Reproducibility of Results
Thyrotropin - blood - chemistry
Abstract
This Canadian Society of Clinical Chemists (CSCC) sponsored position statement addresses the problem of nonuniformity of standardization of polypeptide hormone analyses. First we review the structural diversity of selected polypeptide hormones including growth hormone (GH), prolactin, follitropin (FSH), lutropin (LH), human chorionic gonadotropin (hCG), and thyrotropin (TSH) and the problem that this heterogeneity creates. The history and availability of reference materials for the analyses of these hormones are then summarized. Finally we make a list of recommendations regarding standardization, methods of measurement, and reporting of polypeptide hormone results. Implementation of the recommendations will lead to improvement in inter-laboratory comparability and more useful hormone assays.
PubMed ID
1477965 View in PubMed
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Choriocarcinoma presenting with cerebral metastases after full-term pregnancy.

https://arctichealth.org/en/permalink/ahliterature25391
Source
Acta Obstet Gynecol Scand. 1990;69(5):433-5
Publication Type
Article
Date
1990
Author
K. Pihl
H. Malmström
E. Simonsen
Author Affiliation
Department of Gynecologic Oncology, University Hospital, Linköping, Sweden.
Source
Acta Obstet Gynecol Scand. 1990;69(5):433-5
Date
1990
Language
English
Publication Type
Article
Keywords
Adult
Antineoplastic Combined Chemotherapy Protocols
Brain Neoplasms - secondary
Choriocarcinoma - drug therapy - epidemiology - secondary
Chorionic Gonadotropin - blood
Chorionic Gonadotropin, beta Subunit, Human
Cyclophosphamide - administration & dosage
Dactinomycin - administration & dosage
Female
Humans
Leucovorin - administration & dosage
Methotrexate - administration & dosage
Peptide Fragments - blood
Pregnancy
Sweden - epidemiology
Uterine Neoplasms - drug therapy - epidemiology - pathology
Abstract
Choriocarcinoma is a rare malignancy in Scandinavia. We present a case of a young primigravida who experienced an uneventful pregnancy and gave birth to a healthy baby. Six days after delivery she underwent neurosurgery for intracranial hemorrhage. Pathological examination of the evacuated hematoma revealed metastatic choriocarcinoma. Further work-up exposed additional metastases in the lungs and liver. The initial serum level of human chorionic gonadotropin (beta-HCG) was 350,000 IU/I. Chemotherapy was given both intravenously and intrathecally. At 10 weeks, beta-HCG had returned to normal. Treatment was continued for another 10 weeks. Two years after cessation of therapy the patient is still in complete remission. In the discussion we review a scoring system to be used in selecting the mode of treatment, and briefly mention diagnosis and prognosis.
PubMed ID
1702921 View in PubMed
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Color Doppler flow as an indicator of trophoblastic activity in tubal pregnancies detected by transvaginal ultrasound.

https://arctichealth.org/en/permalink/ahliterature64893
Source
Obstet Gynecol. 1992 Dec;80(6):995-9
Publication Type
Article
Date
Dec-1992
Author
A. Tekay
P. Jouppila
Author Affiliation
Department of Obstetrics and Gynecology, University of Oulu, Finland.
Source
Obstet Gynecol. 1992 Dec;80(6):995-9
Date
Dec-1992
Language
English
Publication Type
Article
Keywords
Adult
Chorionic Gonadotropin - blood
Embryo - blood supply
False Positive Reactions
Female
Humans
Middle Aged
Pregnancy
Pregnancy, Tubal - blood - ultrasonography
Pulsatile Flow
Regional Blood Flow
Trophoblasts - ultrasonography
Ultrasonography - methods
Uterus - blood supply
Vagina
Abstract
OBJECTIVE: To evaluate the potential benefits of transvaginal color Doppler in the diagnostic evaluation of tubal pregnancies. METHODS: Fifty-two women with suspected tubal pregnancy were examined by transvaginal ultrasonography and color Doppler. Those with positive scans were referred for exploratory laparoscopy. The area of the tubal pregnancy was examined by color flow imaging and the resistance indexes (RIs) of the artery blood flows were calculated. The pulsatility indexes (PIs) of both uterine arteries were also measured and serum beta-hCG was quantitated. RESULTS: Tubal pregnancy was diagnosed by transvaginal ultrasonography in 38 of the patients. There were two false-negative and two false-positive results. Color flow in the trophoblastic tissue was detected in 50% of the tubal pregnancies, and the mean (+/- standard deviation) RI of the trophoblastic flows was 0.51 +/- 0.12. The RIs of the trophoblastic flows tended to decrease at higher beta-hCG levels, and 88.2% of the cases with detectable trophoblastic flow had beta-hCG above 800 mIU/mL. The average PI of the uterine arteries was 2.28 +/- 0.89. The PIs of the ipsilateral uterine arteries were significantly lower in the patients with trophoblastic flow than in those without it. CONCLUSION: By monitoring trophoblastic activity, color Doppler may differentiate between active and inactive disease and could assist in choosing the correct treatment.
PubMed ID
1448271 View in PubMed
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Comparison of a local injection of hyperosmolar glucose solution with salpingostomy for the conservative treatment of tubal pregnancy.

https://arctichealth.org/en/permalink/ahliterature64806
Source
Fertil Steril. 1993 Jul;60(1):80-4
Publication Type
Article
Date
Jul-1993
Author
T. Laatikainen
L. Tuomivaara
K. Käär
Author Affiliation
Department of Obstetrics and Gynecology, Oulu University Central Hospital, Finland.
Source
Fertil Steril. 1993 Jul;60(1):80-4
Date
Jul-1993
Language
English
Publication Type
Article
Keywords
Adult
Chorionic Gonadotropin - blood
Chorionic Gonadotropin, beta Subunit, Human
Comparative Study
Female
Glucose Solution, Hypertonic - administration & dosage
Humans
Laparoscopy
Peptide Fragments - blood
Pregnancy
Pregnancy, Tubal - blood - therapy
Prospective Studies
Salpingostomy
Abstract
OBJECTIVE: To compare a local injection of hyperosmolar glucose and salpingostomy for the laparoscopic treatment of tubal pregnancy in terms of immediate success and postoperative tubal patency. DESIGN: Prospective. PATIENTS, SETTING: Forty women with an unruptured tubal pregnancy were enrolled from among 117 women with ectopic pregnancies (EPs) admitted consecutively to the university clinic. The inclusion criteria were as follows: [1] concentration of beta-hCG in the serum
PubMed ID
7685719 View in PubMed
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Concentrations of human chorionic gonadotrophin in very early pregnancy and subsequent pre-eclampsia: a cohort study.

https://arctichealth.org/en/permalink/ahliterature260110
Source
Hum Reprod. 2014 Jun;29(6):1153-60
Publication Type
Article
Date
Jun-2014
Author
B O Asvold
L J Vatten
T G Tanbo
A. Eskild
Source
Hum Reprod. 2014 Jun;29(6):1153-60
Date
Jun-2014
Language
English
Publication Type
Article
Keywords
Adult
Chorionic Gonadotropin - blood
Cohort Studies
Female
Humans
Norway
Pre-Eclampsia - blood
Pregnancy
Pregnancy Trimester, First - blood
Prospective Studies
Risk factors
Abstract
Are low serum concentrations of human chorionic gonadotrophin (hCG) in very early pregnancy associated with pre-eclampsia risk?
Low hCG concentrations in very early pregnancy are associated with increased risk of severe pre-eclampsia.
Low maternal serum concentrations of hCG early in pregnancy may indicate impaired proliferation or invasion of trophoblast cells, and thus low hCG concentrations may serve as a marker for impaired placental development. Impaired placental development is assumed to be a cause of pre-eclampsia, but there is little prospective evidence to support this hypothesis.
We performed a prospective cohort study of pregnancies after IVF at Oslo University Hospital 1996-2010 with linkage to the Medical Birth Registry of Norway to obtain information on pre-eclampsia development.
We included 2405 consecutive singleton pregnancies and examined the association of maternal serum hCG concentrations (measured using Elecsys, Roche) on Day 12 after embryo transfer with the risk of any pre-eclampsia and of mild and severe pre-eclampsia.
HCG concentrations were inversely associated with pre-eclampsia risk in a dose-dependent manner (Ptrend 0.02). Compared with women with hCG =150 IU/l, women with hCG
Notes
Comment In: Womens Health (Lond Engl). 2014 Sep;10(5):483-525335537
PubMed ID
24722241 View in PubMed
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Current clinical features of complete and partial hydatidiform mole in Sweden.

https://arctichealth.org/en/permalink/ahliterature104820
Source
J Reprod Med. 2014 Jan-Feb;59(1-2):51-5
Publication Type
Article
Author
Ulrika Joneborg
Lena Marions
Author Affiliation
Division of Obstetrics and Gynecology, Department of Women's and Children's Health, Karolinska Institutet/Karolinska University Hospital, Stockholm, Sweden. ulrika.joneborg@karolinska.se
Source
J Reprod Med. 2014 Jan-Feb;59(1-2):51-5
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Chorionic Gonadotropin - blood
Female
Gestational Age
Hospitals, University
Humans
Hydatidiform Mole - diagnosis - epidemiology - ultrasonography
Middle Aged
Pregnancy
Retrospective Studies
Sweden - epidemiology
Uterine Hemorrhage
Uterine Neoplasms - diagnosis - epidemiology - ultrasonography
Young Adult
Abstract
To describe the current clinical presentation of complete (CHM) and partial (PHM) hydatidiform mole in a Swedish setting.
A retrospective analysis of medical charts from 331 women with hydatidiform mole (HM) between 1991 and 2010 was performed. Demographics and clinical features were analyzed, and symptoms in women with CHM were compared to those from a historic group (1988 to 1993) from the New England Trophoblastic Disease Center.
In women with CHM, bleeding was more common than in women with PHM (57% vs. 41%, p
PubMed ID
24597287 View in PubMed
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Differential diagnosis of early human pregnancies: impact of different diagnostic measures.

https://arctichealth.org/en/permalink/ahliterature65001
Source
Gynecol Obstet Invest. 1992;33(4):216-20
Publication Type
Article
Date
1992
Author
J. Thorburn
I. Bryman
M. Hahlin
B. Lindblom
Author Affiliation
Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Göteborg, Sweden.
Source
Gynecol Obstet Invest. 1992;33(4):216-20
Date
1992
Language
English
Publication Type
Article
Keywords
Chorionic Gonadotropin - blood
Diagnosis, Differential
Female
Health Status Indicators
Hospitals, University
Humans
Pregnancy
Pregnancy Tests - methods - standards
Pregnancy Trimester, First
Pregnancy, Ectopic - diagnosis - epidemiology - therapy
Progesterone - blood
Prospective Studies
Research Support, Non-U.S. Gov't
Risk factors
Sweden - epidemiology
Ultrasonography, Prenatal - standards
Abstract
A total of 261 women in early pregnancy, either with mild symptoms of ectopic pregnancy (EP) or being at an increased risk for this condition, were included in a longitudinal study. The effectiveness of different diagnostic measures in obtaining correct final diagnoses was analyzed. In addition to clinical findings and symptoms, the use of serum human chorionic gonadotropin, serum progesterone, endovaginal sonography and a risk score for EP were all proven to be valuable in distinguishing normal intrauterine pregnancies from pathological pregnancies.
PubMed ID
1505809 View in PubMed
Less detail

Disappearance of the trophoblastic blood flow in tubal pregnancy after methotrexate injection.

https://arctichealth.org/en/permalink/ahliterature64786
Source
J Ultrasound Med. 1993 Oct;12(10):615-8
Publication Type
Article
Date
Oct-1993

57 records – page 1 of 6.