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2-h postchallenge plasma glucose predicts cardiovascular events in patients with myocardial infarction without known diabetes mellitus.

https://arctichealth.org/en/permalink/ahliterature121853
Source
Cardiovasc Diabetol. 2012;11:93
Publication Type
Article
Date
2012
Author
Loghman Henareh
Stefan Agewall
Author Affiliation
Department of Cardiology Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden. loghman.henareh@karolinska.se
Source
Cardiovasc Diabetol. 2012;11:93
Date
2012
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Angina, Unstable - blood - epidemiology - mortality
Biological Markers - blood
Blood Glucose - metabolism
Chi-Square Distribution
Female
Glucose Tolerance Test
Humans
Incidence
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - blood - epidemiology - mortality
Predictive value of tests
Prognosis
Proportional Hazards Models
Prospective Studies
Recurrence
Risk assessment
Risk factors
Smoking - adverse effects - epidemiology
Stroke - blood - epidemiology - mortality
Sweden - epidemiology
Time Factors
Abstract
The incidence of cardiovascular events remains high in patients with myocardial infarction (MI) despite advances in current therapies. New and better methods for identifying patients at high risk of recurrent cardiovascular (CV) events are needed. This study aimed to analyze the predictive value of an oral glucose tolerance test (OGTT) in patients with acute myocardial infarction without known diabetes mellitus (DM).
The prospective cohort study consisted of 123 men and women aged between 31-80 years who had suffered a previous MI 3-12 months before the examinations. The exclusion criteria were known diabetes mellitus. Patients were followed up over 6.03???1.36 years for CV death, recurrent MI, stroke and unstable angina pectoris. A standard OGTT was performed at baseline.
2-h plasma glucose (HR, 1.27, 95% CI, 1.00 to 1.62; P?
Notes
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PubMed ID
22873202 View in PubMed
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2-year clinical performance of a fluoride-containing fissure sealant in young schoolchildren at caries risk.

https://arctichealth.org/en/permalink/ahliterature34233
Source
Am J Dent. 1997 Jun;10(3):115-9
Publication Type
Article
Date
Jun-1997
Author
A. Carlsson
M. Petersson
S. Twetman
Author Affiliation
Public Dental Clinic, Vallås, Sweden.
Source
Am J Dent. 1997 Jun;10(3):115-9
Date
Jun-1997
Language
English
Publication Type
Article
Keywords
Analysis of Variance
Cariostatic Agents - analysis - therapeutic use
Chi-Square Distribution
Child
Colony Count, Microbial
Composite Resins - chemistry - therapeutic use
Dental Caries - epidemiology - prevention & control
Dental Plaque - microbiology
Fluorides - analysis - pharmacology - therapeutic use
Humans
Lactobacillus - drug effects - isolation & purification
Pit and Fissure Sealants - therapeutic use
Prevalence
Risk assessment
Saliva - chemistry - microbiology
Statistics, nonparametric
Streptococcus mutans - drug effects - isolation & purification
Sweden - epidemiology
Abstract
PURPOSE: To evaluate the clinical performance of Helioseal-F, a fluoride-containing fissure sealant, in school children at caries risk. MATERIALS AND METHODS: A caries risk assessment based on past caries experience, saliva microbial tests, buffer capacity and frequency of sugar intake was carried out in 204 healthy children, 6-7 years of age. Children exhibiting one or more risk factors were considered at caries risk (n = 121) and their permanent molars were sealed with a fluoride-containing fissure sealant, thus forming a fissure sealant group (FSG). The remaining 83 children with low caries risk received no fissure sealants and constituted a reference group (RG). Both groups were followed for 2 years. From 15 children of both groups, unstimulated whole saliva was collected 1 month after sealant placement in order to determine fluoride levels. In another 20 children, a split-mouth study design was utilized to compare the colonization of mutans streptococci adjacent to and on F-containing sealants and conventional controls. The sealants were placed by dental hygienists according to the manufacturers' instructions. RESULTS: A total of 431 fissure sealants were placed at baseline. Complete retention was found in 76.6% during the study period while 22.0% were partially lost. Six sealants (1.4%) were completely lost. The enamel caries incidence was 45% lower (P
PubMed ID
9545884 View in PubMed
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A 2-year self-help smoking cessation manual intervention among middle-aged Finnish men: an application of the transtheoretical model.

https://arctichealth.org/en/permalink/ahliterature217852
Source
Prev Med. 1994 Jul;23(4):507-14
Publication Type
Article
Date
Jul-1994
Author
U E Pallonen
L. Leskinen
J O Prochaska
C J Willey
R. Kääriäinen
J T Salonen
Author Affiliation
Cancer Prevention Research Center, University of Rhode Island, Kingston 02881.
Source
Prev Med. 1994 Jul;23(4):507-14
Date
Jul-1994
Language
English
Publication Type
Article
Keywords
Adult
Analysis of Variance
Chi-Square Distribution
Confounding Factors (Epidemiology)
Finland
Humans
Longitudinal Studies
Male
Manuals as Topic
Middle Aged
Risk factors
Self Care
Smoking Cessation
Abstract
A 2-year self-help manual smoking cessation intervention was conducted among a panel of middle-aged Finnish men (n = 265) who were recruited proactively in a longitudinal cardiovascular risk factor surveillance study.
Intervention utilized the stages of change concept of the transtheoretical model. The stages were assessed in the treatment condition at baseline of the cessation study and after that by mail every sixth month. Assessments were followed by an immediate mailing of a stage-based self-help manual matching the stage of change at that time. A usual care group was assessed annually but received no treatment.
A significant time x intervention effect (P
PubMed ID
7971879 View in PubMed
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A 5-year follow-up of occlusal status and radiographic findings in mandibular condyles of the elderly.

https://arctichealth.org/en/permalink/ahliterature187416
Source
Int J Prosthodont. 2002 Nov-Dec;15(6):539-43
Publication Type
Article
Author
Kaija Hiltunen
Miira M Vehkalahti
Jaakko S Peltola
Anja Ainamo
Author Affiliation
Department of Prosthodontics, Institute of Dentistry, University of Helsinki, Finland. kaija.hiltunen@helsinki.fi
Source
Int J Prosthodont. 2002 Nov-Dec;15(6):539-43
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Aged, 80 and over
Chi-Square Distribution
Confidence Intervals
Dentition
Denture, Partial, Fixed
Dentures
Dislocations - classification - radiography
Female
Finland
Follow-Up Studies
Humans
Jaw, Edentulous, Partially - classification - rehabilitation
Logistic Models
Male
Mandibular Condyle - radiography
Odds Ratio
Osteoarthritis - classification - radiography
Osteosclerosis - classification - radiography
Radiography, Panoramic
Risk factors
Sex Factors
Temporomandibular Joint Disorders - classification - radiography
Abstract
The aim of the present 5-year follow-up was to clarify the nature of occlusal support status and radiographic changes in condyles of the elderly, and the association between these two variables.
The present study is part of a comprehensive medical survey of a random sample born in 1904, 1909, and 1914. A total of 364 subjects living in Helsinki participated in the dental part of the examination during 1990 to 1991, and after 5 years a total of 103 were reexamined. Comprehensive data on occlusal support status were available for 94 subjects, and radiographic data were available for 88 subjects. Occlusal support status was assessed on the basis of the Eichner index, radiographic changes were assessed from panoramic radiographs, and symptoms of temporomandibular disorders were assessed using Helkimo's anamnestic index.
The most frequent radiographic finding in the mandibular joint was flattening of the articular surface of the condyle associated with osteoarthrosis, found at baseline in 17% and during follow-up in 13% of the subjects. During the 5-year follow-up, Eichner index for natural dentition remained unaltered in 94% of the subjects and in 85% of the subjects when removable dentures were included. There were no radiographic changes in 92% of the cases. No differences based on age or gender were found. A logistic regression model revealed associations between the selected baseline factors. The odds ratio for baseline Helkimo's anamnestic index was 4.1, 5.7 for Eichner index with the support of removable dentures, and 356 for radiographic findings.
Radiographic changes in condyles of elderly people were small during the 5-year follow-up, but baseline radiographic findings, Helkimo's anamnestic index, and Eichner index with removable dentures were risk factors for radiographic findings at the end of the follow-up.
PubMed ID
12475158 View in PubMed
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A 5-year follow-up of signs and symptoms of TMD and radiographic findings in the elderly.

https://arctichealth.org/en/permalink/ahliterature182090
Source
Int J Prosthodont. 2003 Nov-Dec;16(6):631-4
Publication Type
Article
Author
Kaija Hiltunen
Jaakko S Peltola
Miira M Vehkalahti
Timo Närhi
Anja Ainamo
Author Affiliation
Department of Prosthodontics, Institute of Dentistry, University of Helsinki, Finland. kaija.hiltunen@helsinki.fi
Source
Int J Prosthodont. 2003 Nov-Dec;16(6):631-4
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Chi-Square Distribution
Cohort Studies
Female
Finland
Follow-Up Studies
Humans
Male
Mandibular Condyle - physiopathology - radiography
Radiography, Panoramic
Range of Motion, Articular - physiology
Sex Factors
Temporomandibular Joint - physiopathology - radiography
Temporomandibular Joint Disorders - classification - physiopathology - radiography
Abstract
The aim was to clarify the associations among subjective symptoms, clinical signs of temporomandibular disorders (TMD), and radiographic findings in the mandibular condyles of elderly people during a 5-year follow-up.
As part of a comprehensive medical survey of a random sample born in 1904, 1909, and 1914 (Helsinki Aging Study), 364 subjects living in Helsinki participated in the dental part of the examination during 1990 and 1991; after 5 years, 103 of these were reexamined. Comprehensive data on TMD were available for 94 subjects, and radiographic data were available for 88. TMD were assessed by Helkimo's anamnestic and clinical indices, and radiographic status was assessed by panoramic radiographs.
During the 5-year follow-up, reported anamnestic symptoms of TMD for men changed little (9%); among women, the change from baseline was 42%. When the unchanged indices were compared, the gender difference was obvious. At baseline, 5% of the women, but no men, had severe signs (clinical index III) of TMD. At the end of follow-up, none showed severe signs. Comparison of radiographic findings between baseline and follow-up showed no differences, nor did differences appear in associations between radiographic findings and anamnestic or clinical indices.
During the 5-year follow-up, signs and symptoms of TMD in these elderly individuals became milder or vanished. The radiographic status of the condyles remained stable, and no association appeared between radiographic findings and signs and symptoms of TMD.
PubMed ID
14714843 View in PubMed
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5-year review of a unique multidisciplinary nonmelanoma skin cancer clinic.

https://arctichealth.org/en/permalink/ahliterature132764
Source
J Cutan Med Surg. 2011 Jul-Aug;15(4):220-6
Publication Type
Article
Author
Shaelyn Culleton
Dale Breen
Dalal Assaad
Liying Zhang
Judith Balogh
May Tsao
Juhu Kamra
Greg Czarnota
Oleh Antonyshyn
Jeffery Fialkov
Elizabeth Barnes
Author Affiliation
Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
Source
J Cutan Med Surg. 2011 Jul-Aug;15(4):220-6
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Aged, 80 and over
Biopsy
Carcinoma, Basal Cell - pathology - therapy
Carcinoma, Squamous Cell - pathology - therapy
Chi-Square Distribution
Child
Delivery of Health Care, Integrated - organization & administration
Female
Humans
Male
Middle Aged
Ontario
Outcome and Process Assessment (Health Care)
Skin Neoplasms - pathology - therapy
Abstract
A multidisciplinary nonmelanoma skin cancer (NMSC) clinic is held weekly at our center, where all new patients are jointly assessed by dermatology/dermatopathology, radiation oncology, and plastic surgery. A new patient database was established in 2004. The purpose of this study was to provide a preliminary report on the patients seen in the NMSC clinic and the treatment recommendations rendered.
The new patient database was reviewed from January 2004 to December 2008, and patient demographics, tumor characteristics, and treatment recommendations were extracted. Cochran-Mantel-Harnszel (CMH) testing and chi-square analysis were used to detect any associations or relationships between variables within the database. A p value of less than .05 was considered significant.
During the 5-year study period, 2,146 new patients were seen in the NMSC clinic. The majority of patients presented with basal cell carcinoma (64%) or squamous cell carcinoma (22%), with a median tumor size of 1 to 2 cm (range 0 to > 9 cm). Tumors were located in the head and neck region (80%), extremities (14%), and torso (6%). Previous treatment included biopsy only (62%), surgery (20%), electrodesiccation and curettage (11%), topical imiquimod (3%), and radiotherapy (1%). Treatment recommendations included surgery (55%) (with either simple excision [31%] or excision with margin control under frozen-section guidance [24%]), radiotherapy (19%), topical imiquimod (10%), observation (7%), and electrodesiccation and curettage (4%).
The NMSC clinic at our center sees a high volume of patients who benefit from the multidisciplinary assessment provided. Treatment recommendations were based on patient and disease characteristics as well as patient preference.
PubMed ID
21781628 View in PubMed
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A 7-year retrospective review from 2005 to 2011 of Propionibacterium acnes shoulder infections in Ottawa, Ontario, Canada.

https://arctichealth.org/en/permalink/ahliterature117999
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Publication Type
Article
Date
Feb-2013
Author
Bing Wang
Baldwin Toye
Marc Desjardins
Peter Lapner
Craig Lee
Author Affiliation
Division of Microbiology, Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada.
Source
Diagn Microbiol Infect Dis. 2013 Feb;75(2):195-9
Date
Feb-2013
Language
English
Publication Type
Article
Keywords
Adult
Aged
Arthroplasty
Chi-Square Distribution
Female
Gram-Positive Bacterial Infections - epidemiology - microbiology
Humans
Joint Diseases - epidemiology - microbiology
Male
Middle Aged
Ontario - epidemiology
Propionibacterium acnes - isolation & purification
Prosthesis-Related Infections - epidemiology - microbiology
Retrospective Studies
Shoulder Joint - microbiology
Abstract
This study evaluated the clinical factors associated with Propionibacterium acnes shoulder infection and the standard culture procedures for isolating P. acnes from shoulder specimens by a 7-year retrospective analysis. P. acnes was incriminated as the second most common pathogen in 17 of 80 patients with positive shoulder cultures. All of the 17 patients had prior shoulder implant. The cumulative rates for isolating P. acnes were 1.9%, 1.9%, 41.9%, 96.4%, and 100% at day 1 to day 5 of incubation, respectively. The standard practice of anaerobic culture was able to detect P. acnes from shoulder specimens in patients with a clinical suspicion of infection. The sensitivity and specificity of prolonged incubation remain to be determined.
PubMed ID
23246074 View in PubMed
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A 24-year follow-up of root filled teeth and periapical health amongst middle aged and elderly women in Göteborg, Sweden.

https://arctichealth.org/en/permalink/ahliterature70741
Source
Int Endod J. 2005 Apr;38(4):246-54
Publication Type
Article
Date
Apr-2005
Author
F. Frisk
M. Hakeberg
Author Affiliation
Department of Endodontology/Oral Diagnosis, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden. fredrik.frisk@lio.se
Source
Int Endod J. 2005 Apr;38(4):246-54
Date
Apr-2005
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Analysis of Variance
Chi-Square Distribution
Cross-Sectional Studies
Female
Humans
Linear Models
Longitudinal Studies
Middle Aged
Mouth, Edentulous - epidemiology
Periapical Periodontitis - epidemiology
Prevalence
Questionnaires
Radiography, Panoramic
Research Support, Non-U.S. Gov't
Sweden - epidemiology
Tooth Loss - epidemiology
Tooth, Nonvital - epidemiology
Abstract
AIM: To describe the endodontic status amongst middle-aged and elderly women longitudinally and cross-sectionally over 24 years. METHODOLOGY: A random sample of 1462 women 38, 46, 50, 54 and 60 years old, living in Göteborg, Sweden, were sampled in 1968 for medical and dental examinations with a participation rate of 90.1%. The same women were re-examined in 1980 and 1992 together with new 38- and 50-year-old women. The dental examination consisted of questionnaires, clinical and panoramic radiological survey (OPG). The number of teeth, number of root filled teeth (RF) and number of teeth with periapical radiolucencies (PA) were registered. The RF and PA ratios were calculated. Cross-sectional data were analysed by means of anova and longitudinal data by a general linear model for repeated measures. Sample prevalences were compared and statistical inferences were made with the chi-squared test. In all analysis, the confidence interval (CI) regarded mean difference between groups (95% CI). RESULTS: The RF and PA ratio decreased over time as well as the frequency of edentulous subjects. Cross-sectional analysis revealed a minor increase in frequency of RF and PA and loss of teeth with age. Longitudinally, loss of teeth was evident in all cohorts. In addition, there was a trend of lower number of teeth with PA, and the RF ratio increased with age. CONCLUSIONS: The prevalence of periapical disease did not increase with age, probably as a result of root canal treatment and extractions. Data showed that the prevalence of RF teeth and teeth with PA decreased for comparable age cohorts during the 24-year follow-up.
PubMed ID
15810975 View in PubMed
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A 45-year experience with surgical treatment of peptic ulcer disease in children.

https://arctichealth.org/en/permalink/ahliterature211771
Source
J Pediatr Surg. 1996 Jun;31(6):750-3
Publication Type
Article
Date
Jun-1996
Author
K. Azarow
P. Kim
B. Shandling
S. Ein
Author Affiliation
Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
Source
J Pediatr Surg. 1996 Jun;31(6):750-3
Date
Jun-1996
Language
English
Publication Type
Article
Keywords
Anti-Ulcer Agents - therapeutic use
Chi-Square Distribution
Child
Gastric Outlet Obstruction - etiology - surgery
Gastrointestinal Hemorrhage - etiology - surgery
Histamine H2 Antagonists - therapeutic use
Humans
Intestinal Perforation - etiology - surgery
Ontario
Peptic Ulcer - complications - drug therapy - surgery
Proton Pump Inhibitors
Retrospective Studies
Abstract
Peptic ulcer disease (PUD) requiring surgical treatment has become rare with the availability of modern medical management. A retrospective study of all patients who required operations for PUD between 1949 and 1994 (n = 43) was done. The patients were classified into 3 groups: A (n = 38): pre-histamine-2 (H2) blocker era (1949-1975); B (n = 3): pre-hydrogen-potassium (H-K+) ATPase inhibitor era (1976-1988); C (n = 2): H-K+ ATPase inhibitor era (1989-1994). Data, analyzed using X2 analysis (P .01). Children with PUD can have complications similar to those of adults with PUD. Since the introduction of H2 antagonists, the recognition and treatment of H pylori, and the use of H-K+ ATPase inhibition, the incidence of operations for bleeding and perforation has decreased dramatically. However, the incidence of surgery for obstruction remains the same.
PubMed ID
8783092 View in PubMed
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A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome.

https://arctichealth.org/en/permalink/ahliterature145472
Source
J Hum Hypertens. 2010 Nov;24(11):739-48
Publication Type
Article
Date
Nov-2010
Author
N. Racine
P. Hamet
J S Sampalis
N. Longo
N. Bastien
Author Affiliation
Department of Medicine, Montreal Heart Institute, Montréal, Québec, Canada.
Source
J Hum Hypertens. 2010 Nov;24(11):739-48
Date
Nov-2010
Language
English
Publication Type
Article
Keywords
Adult
Aged
Angiotensin II Type 1 Receptor Blockers - adverse effects - therapeutic use
Antihypertensive Agents - adverse effects - therapeutic use
Biological Markers - blood
Blood Glucose - drug effects - metabolism
Blood Pressure - drug effects
Calcium Channel Blockers - therapeutic use
Canada
Chi-Square Distribution
Diabetes Mellitus - blood - chemically induced
Diuretics - adverse effects - therapeutic use
Drug Therapy, Combination
Female
Hemoglobin A, Glycosylated - metabolism
Humans
Hydrochlorothiazide - adverse effects - therapeutic use
Hypertension - blood - complications - drug therapy - physiopathology
Linear Models
Losartan - adverse effects - therapeutic use
Male
Metabolic Syndrome X - blood - complications - physiopathology
Middle Aged
Prospective Studies
Risk assessment
Risk factors
Time Factors
Treatment Outcome
Abstract
The impact of an ARB, with or without hydrochlorothiazide (HCTZ), on glycaemic factors and the risk for developing diabetes in hypertensive patients with the metabolic syndrome have not been fully assessed. This was a 52-week multicentre, prospective, phase-IV, open-label, cohort study of losartan or losartan/HCTZ in hypertensive patients with metabolic syndrome. All subjects were treated initially with losartan 50?mg?day(-1). Those not achieving target blood pressure (BP
PubMed ID
20147971 View in PubMed
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2861 records – page 1 of 287.