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Methylphenidate misuse in adult patients and the impact of therapeutic use.

https://arctichealth.org/en/permalink/ahliterature269347
Source
Hum Exp Toxicol. 2015 May;34(5):460-7
Publication Type
Article
Date
May-2015
Author
L S Jensen
A K Pagsberg
K. Dalhoff
Source
Hum Exp Toxicol. 2015 May;34(5):460-7
Date
May-2015
Language
English
Publication Type
Article
Keywords
Adult
Attention Deficit Disorder with Hyperactivity - drug therapy - epidemiology - psychology
Central Nervous System Stimulants - administration & dosage - poisoning - therapeutic use
Data Interpretation, Statistical
Denmark - epidemiology
Female
Humans
Male
Methylphenidate - administration & dosage - poisoning - therapeutic use
Poisoning - epidemiology - etiology - psychology
Prescription Drug Misuse - psychology - statistics & numerical data
Retrospective Studies
Substance-Related Disorders - epidemiology - etiology - psychology
Suicide, Attempted - psychology - statistics & numerical data
Abstract
Methylphenidate (MPH) prescription rates for adults increase, but the extent of a parallel rise in toxic exposures and their causes and distribution between different MPH trade names are unexplored.
We retrospectively analyzed adult MPH exposures reported to the Danish Poison Information Centre from January 2006 to July 2012 and the association with MPH sales and the number of patients prescribed MPH.
Of the 394 exposures (57% males, median age 27 years) reported, MPH status was available in 249 of whom 65.5% were prescribed MPH. Exposure was in 54% motivated by suicidal attempt and in 40% by recreational use (based on 375 cases). Exposure was dominated by one trade name and exposure incidence correlated significantly with sales (?p = 0.001) and prevalence of MPH-treated patients (?p = 0.0008).
The increase in MPH exposures parallels the prescription rates (particularly Ritalin(®)/Ritalin(®) Uno). Most exposures were intentional and motivated by suicide attempts or recreational use.
PubMed ID
25062974 View in PubMed
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Time to address stimulant abuse on our campuses.

https://arctichealth.org/en/permalink/ahliterature131572
Source
CMAJ. 2011 Sep 6;183(12):1345
Publication Type
Article
Date
Sep-6-2011
Author
Daniel Rosenfield
Paul C Hébert
Matthew B Stanbrook
Ken Flegel
Noni E MacDonald
Source
CMAJ. 2011 Sep 6;183(12):1345
Date
Sep-6-2011
Language
English
Publication Type
Article
Keywords
Canada
Central Nervous System Stimulants - administration & dosage - poisoning
Drug Overdose
Drug and Narcotic Control
Health education
Humans
Substance-Related Disorders - prevention & control
Universities
Notes
Cites: Pharmacol Biochem Behav. 2001 Mar;68(3):611-2711325419
Cites: Can J Psychiatry. 2005 Jul;50(8):457-6116127963
Cites: J Atten Disord. 2009 Nov;13(3):284-9619767596
Cites: Eur Arch Psychiatry Clin Neurosci. 2008 Nov;258 Suppl 5:110-418985306
Cites: J Am Acad Child Adolesc Psychiatry. 2008 Jan;47(1):21-3118174822
PubMed ID
21896701 View in PubMed
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