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Cardiovascular biomarkers predict fragility fractures in older adults.

https://arctichealth.org/en/permalink/ahliterature299736
Source
Heart. 2019 03; 105(6):449-454
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
03-2019
Author
Madeleine Johansson
Fabrizio Ricci
Giuseppe Di Martino
Cecilia Rogmark
Richard Sutton
Viktor Hamrefors
Olle Melander
Artur Fedorowski
Author Affiliation
Department of Clinical Sciences, Faculty of Medicine, Clinical Research Center, Lund University, Malmö, Sweden.
Source
Heart. 2019 03; 105(6):449-454
Date
03-2019
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adrenomedullin - blood
Aged
Atrial Natriuretic Factor - blood
Biomarkers - blood
Body mass index
Cardiovascular System - metabolism
Cohort Studies
Correlation of Data
Endothelin-1 - blood
Female
Fractures, Bone - blood
Humans
Independent Living - statistics & numerical data
Male
Middle Aged
Peptide Fragments - blood
Prospective Studies
Protein Precursors - blood
Reproducibility of Results
Risk assessment
Risk factors
Sweden
Vasopressins - blood
Abstract
To assess the role of four biomarkers of neuroendocrine activation and endothelial dysfunction in the longitudinal prediction of fragility fractures.
We analysed a population-based prospective cohort of 5415 community-dwelling individuals (mean age, 68.9±6.2 years) enrolled in the Malmö Preventive Project followed during 8.1±2.9 years, and investigated the longitudinal association between C-terminal pro-arginine vasopressin (CT-proAVP), C-terminal endothelin-1 precursor fragment (CT-proET-1), the mid-regional fragments of pro-adrenomedullin (MR-proADM) and pro-atrial natriuretic peptide (MR-proANP), and incident vertebral, pelvic and extremity fractures.
Overall, 1030 (19.0%) individuals suffered vertebral, pelvic or extremity fracture. They were older (70.7±5.8 vs 68.4±6.3 years), more likely women (46.9% vs 26.3%), had lower body mass index and diastolic blood pressure, were more often on antihypertensive treatment (44.1% vs 38.4%) and had more frequently history of fracture (16.3% vs 8.1%). Higher levels of MR-proADM (adjusted HR (aHR) per 1 SD: 1.51, 95% CI 1.01 to 2.28, p
Notes
CommentIn: Heart. 2019 Mar;105(6):427-428 PMID 30361269
PubMed ID
30322844 View in PubMed
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Effect of cobalt on parameters of the cardiovascular system in elementary school children.

https://arctichealth.org/en/permalink/ahliterature259751
Source
Bull Exp Biol Med. 2013 Jul;155(3):312-3
Publication Type
Article
Date
Jul-2013
Author
N V Svyatova
F G Sitdikov
E S Egerev
Source
Bull Exp Biol Med. 2013 Jul;155(3):312-3
Date
Jul-2013
Language
English
Publication Type
Article
Keywords
Blood Circulation
Body mass index
Cardiovascular System - metabolism
Child
Child Development - physiology
Cobalt - analysis - deficiency - metabolism
Deficiency Diseases - epidemiology
Female
Hair - chemistry
Hemodynamics - physiology
Humans
Incidence
Mass Spectrometry
Plethysmography, Impedance
Pulse
Russia - epidemiology
Spectrophotometry, Atomic
Abstract
High incidence of cobalt deficiency (89%) was found in 7-8-year-old girls residents of the Republic of Tatarstan. Significant correlations were revealed between parameters of physical development and cardiovascular system and hair cobalt content. These data suggest that positive balance of cobalt is essential for normal growth and development of child's body and function of the cardiovascular system.
PubMed ID
24137591 View in PubMed
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Incidental physical activity is positively associated with cardiorespiratory fitness.

https://arctichealth.org/en/permalink/ahliterature135186
Source
Med Sci Sports Exerc. 2011 Nov;43(11):2189-94
Publication Type
Article
Date
Nov-2011
Author
K Ashlee McGuire
Robert Ross
Author Affiliation
School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada. rossr@queensu.ca
Source
Med Sci Sports Exerc. 2011 Nov;43(11):2189-94
Date
Nov-2011
Language
English
Publication Type
Article
Keywords
Adult
Aged
Anthropometry
Cardiovascular System - metabolism
Exercise Test
Female
Humans
Male
Middle Aged
Obesity
Ontario
Oxygen consumption
Physical Exertion - physiology
Physical Fitness - physiology
Risk factors
Abstract
The primary aim was to determine whether incidental physical activity (IPA), expressed either as duration or intensity, was associated with cardiorespiratory fitness (CRF).
Participants were inactive abdominally obese men (n = 43, waist circumference = 102 cm) and women (n = 92, waist circumference = 88 cm) recruited from Kingston, Canada. IPA (>100 counts per minute) was determined by accelerometry during 7 d and categorized into duration (min·d(-1)) and intensity (counts per minute). In secondary analyses, IPA was further categorized as light physical activity (LPA, 100-1951 counts per minute) and sporadic moderate physical activity (MPA, = 1952 counts per minute accumulated in bouts 0.05). Sporadic MPA was associated with CRF (r2 = 0.20, P
Notes
Erratum In: Med Sci Sports Exerc. 2012 Mar;44(3):562
PubMed ID
21502894 View in PubMed
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[Methodological approaches to the hygienic evaluation of total artificial lighting of classrooms with different light sources on the basis of the response of the cardiovascular system of schoolchildren].

https://arctichealth.org/en/permalink/ahliterature104467
Source
Gig Sanit. 2014 Jan-Feb;(1):98-102
Publication Type
Article
Author
L M Teksheva
I V Zvezdina
Source
Gig Sanit. 2014 Jan-Feb;(1):98-102
Language
Russian
Publication Type
Article
Keywords
Adaptation, Physiological
Cardiovascular System - metabolism
Child
Female
Heart Rate - physiology
Humans
Light
Lighting
Male
Russia
Schools
Students
Abstract
Hygienic evaluation of innovative equipment in educational institutions requires the use of appropriate methods permitting to establish valuable criterias for the effectiveness of the application of new technologies. The study of the response of the cardiovascular system of schoolchildren under using different light sources allowed to establish the increase in adaptive capacities and the improvement of the functional state of the organism in LED in comparison with fluorescent lighting.
PubMed ID
24749295 View in PubMed
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[Structurally functional changes of cardiovascular system at high sports activity at aboriginals of Yakutia]

https://arctichealth.org/en/permalink/ahliterature97150
Source
Fiziol Cheloveka. 2010 Mar-Apr;36(2):130-7
Publication Type
Article
Author
I A Pinigina
N V Makharova
S G Krivoshchekov
Source
Fiziol Cheloveka. 2010 Mar-Apr;36(2):130-7
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Boxing - physiology
Cardiovascular System - metabolism
Ethnic Groups
Hemodynamics
Humans
Lipids - blood
Male
Siberia - ethnology
Wrestling - physiology
Abstract
In order to study structurally functional changes of cardiovascular system and metabolic indicators at going in for sports in Yakutia, 146 men of the Yakut nationality (18-29 years) living in Yakutsk city have been surveyed. The basic group - sportsmen of high level of skill (free-style wresling, boxing) (n = 108, middle age 20.2 +/- 0.2 years). Control group - the healthy men who are not going in for sports (n = 38, middle age 24.5 +/- 0.4 years). METHODS: anthropometry, echocardiography, rheography, arterial pressure (AP), biochemical analysis of blood serum. The basic group has been divided into 2 subgroups depending on level AP (1a-AP sist from 110 to 130, group 1b-AP sist more than 130 mm Hg). Results of research have shown, that playing sports leads to specialized changes of functioning of cardiovascular system, conserned with point of view on "adaptation to function" and "sports heart". Condition of the North can promote occurrence of changes at separate sportsmen (risk group - 10%) who are shown by disorder of hemodynamic parameters at at preservation of normal values of indicators of blood lipid profile.
PubMed ID
20432702 View in PubMed
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[The influence of structural and functional disorders in cardiovascular and renal systems and metabolic disturbances on perinatal outcomes in pregnant women with chronic arterial hypertension].

https://arctichealth.org/en/permalink/ahliterature262244
Source
Klin Med (Mosk). 2014;92(5):40-6
Publication Type
Article
Date
2014
Author
A V Padyganova
E N Chicherina
Source
Klin Med (Mosk). 2014;92(5):40-6
Date
2014
Language
Russian
Publication Type
Article
Keywords
Adult
Blood Pressure Determination
Cardiovascular System - metabolism - pathology - physiopathology
Dyslipidemias - diagnosis
Female
Glomerular Filtration Rate
Heart Function Tests - methods
Humans
Hypertension - diagnosis - metabolism - physiopathology
Infant, Low Birth Weight
Infant, Newborn
Kidney - metabolism - pathology - physiopathology
Pregnancy
Pregnancy Complications, Cardiovascular - diagnosis - metabolism - physiopathology
Pregnancy outcome
Prospective Studies
Russia
Ventricular Remodeling
Abstract
We studied the influence of structural and functional disorders in cardiovascular and renal system and metabolic disturbances on perinatal outcomes in pregnant women with chronic arterial hypertension. The study included 100 women with these pathologies and 30 patients with physiological pregnancy. Comprehensive evaluation of the cardiovascular system, metabolic status, and perinatal outcomes was undertaken. The results indicate that atherogenic dyslipidemia is significantly associated with the reduction of body mass while glomerular filtration rate, concentric and eccentric left ventricular hypertrophy with the decrease of both weight and height of the newborns.
PubMed ID
25782305 View in PubMed
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6 records – page 1 of 1.