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Baseline comparison of three health utility measures and the feeling thermometer among participants in the Action to Control Cardiovascular Risk in Diabetes trial.
Cardiovasc Diabetol. 2012;11:35
Publication Type
Dennis W Raisch
Patricia Feeney
David C Goff
K M Venkat Narayan
Patrick J O'Connor
Ping Zhang
Don G Hire
Mark D Sullivan
Author Affiliation
University of New Mexico Health Sciences Center, 1 University of New Mexico, Albuquerque, NM 87131, USA.
Cardiovasc Diabetol. 2012;11:35
Publication Type
Cardiovascular Diseases - etiology - physiopathology - prevention & control - psychology
Diabetes Complications - etiology - physiopathology - prevention & control - psychology
Diabetes Mellitus, Type 2 - complications - diagnosis - physiopathology - psychology - therapy
Health status
Health Status Indicators
Middle Aged
Multivariate Analysis
Predictive value of tests
Quality of Life
Risk assessment
Risk factors
United States
Health utility (HU) measures are used as overall measures of quality of life and to determine quality adjusted life years (QALYs) in economic analyses. We compared baseline values of three HUs including Short Form 6 Dimensions (SF-6D), and Health Utilities Index, Mark II and Mark III (HUI2 and HUI3) and the feeling thermometer (FT) among type 2 diabetes participants in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. We assessed relationships between HU and FT values and patient demographics and clinical variables.
ACCORD was a randomized clinical trial to test if intensive controls of glucose, blood pressure and lipids can reduce the risk of major cardiovascular disease (CVD) events in type 2 diabetes patients with high risk of CVD. The health-related quality of life (HRQOL) sub-study includes 2,053 randomly selected participants. Interclass correlations (ICCs) and agreement between measures by quartile were used to evaluate relationships between HU's and the FT. Multivariable regression models specified relationships between patient variables and each HU and the FT.
The ICCs were 0.245 for FT/SF-6D, 0.313 for HUI3/SF-6D, 0.437 for HUI2/SF-6D, 0.338 for FT/HUI2, 0.337 for FT/HUI3 and 0.751 for HUI2/HUI3 (P ?
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PubMed ID
22515638 View in PubMed
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