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Mortality associated with periodic limb movements during sleep in amyotrophic lateral sclerosis patients.

https://arctichealth.org/en/permalink/ahliterature116546
Source
Einstein (Sao Paulo). 2012 Oct-Dec;10(4):428-32
Publication Type
Article
Author
Alexander Joseph Moszczynski
Anu Tandon
Fernando Morgadinho Santos Coelho
Lorne Zinman
Brian Murray
Author Affiliation
University of Toronto, Toronto, Canada.
Source
Einstein (Sao Paulo). 2012 Oct-Dec;10(4):428-32
Language
English
Portuguese
Publication Type
Article
Keywords
Aged
Amyotrophic Lateral Sclerosis - mortality
Canada - epidemiology
Case-Control Studies
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Nocturnal Myoclonus Syndrome - epidemiology
Polysomnography
Prevalence
Severity of Illness Index
Sleep
Sleep Apnea Syndromes - diagnosis
Statistics, nonparametric
Symptom Assessment
Abstract
To describe the prevalence and severity of periodic limb movements during sleep in amyotrophic lateral sclerosis patients and to explore this fact as a predictor of severity of the condition with respect to mortality.
In this case-control study, questionnaire and polysomnographic data were analyzed from 35 amyotrophic lateral sclerosis patients. Controls were matched by age, genre, and body mass index. A Kaplan-Meier curve was used to compare the survival time of patients with periodic limb movements of sleep index below or above 5.
The number of amyotrophic lateral sclerosis patients with an index greater than five was higher than controls (19 (53%) versus 4 (11%); p
PubMed ID
23386081 View in PubMed
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