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199 records – page 1 of 20.

25-Hydroxycholecaliferol and fractures of the proximal.

https://arctichealth.org/en/permalink/ahliterature252013
Source
Lancet. 1975 Aug 16;2(7929):300-2
Publication Type
Article
Date
Aug-16-1975
Author
B. Lund
O H Sorensen
A B Christensen
Source
Lancet. 1975 Aug 16;2(7929):300-2
Date
Aug-16-1975
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Alkaline Phosphatase - blood
Calcium - blood
Clinical Trials as Topic
Denmark
Femoral Fractures - blood - epidemiology - etiology
Great Britain
Humans
Hydroxycholecalciferols - blood - metabolism
Kidney - metabolism
Middle Aged
Osteomalacia - blood - complications - etiology
Phosphorus - blood
Seasons
Vitamin D - administration & dosage
Abstract
Plasma 25-hydroxycholecalciferol (25-H.C.C.) has been measured in 67 consective cases of fracture of the proximal femur. The values found in these patients were not different from values found in these patients were not different from those in control groups at the same time of the year. Plasma 25-H.C.C. was not correlated to plasma calcium or phosphorus, the Ca times P product, or the alkaline phosphatase. X-rays showed Looser zones in only 1 patient, in whom the lowest plasma 25-H.C.C. was found. Osteomalacia is not uncommon among elderly people in Denmark, but it is more likely to depend on a decline in the renal efficiency to convert 25-H.C.C. to 1,25-dihydroxycholecalciferol than a low dietary intake of vitamin D.
PubMed ID
50509 View in PubMed
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25-Hydroxyvitamin D concentrations in maternal and cord blood at delivery and in maternal blood during lactation in Finland.

https://arctichealth.org/en/permalink/ahliterature240391
Source
Hum Nutr Clin Nutr. 1984 Jul;38(4):261-8
Publication Type
Article
Date
Jul-1984
Author
C. Lamberg-Allardt
M. Larjosto
E. Schultz
Source
Hum Nutr Clin Nutr. 1984 Jul;38(4):261-8
Date
Jul-1984
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Alkaline Phosphatase - blood
Calcifediol - blood
Calcium - blood
Cholecalciferol - administration & dosage
Female
Fetal Blood - metabolism
Finland
Food Habits
Humans
Infant, Newborn
Lactation
Maternal-Fetal Exchange
Nutritional Requirements
Pregnancy
Seasons
Vitamin D Deficiency - blood
Abstract
The 25-hydroxyvitamin D concentration (25-OHD) in maternal and cord blood of 192 mothers was determined at delivery from June to the end of November. Ninety-nine mothers had received a daily supplementation of 12.5 micrograms of vitamin D during pregnancy and this group had a significantly higher 25-OHD concentration both in maternal and in cord blood than in the corresponding non-supplemented group. A daily supplement of 2.5 micrograms of vitamin D was given to 63 of the mothers during lactation. Of these mothers 44 were still lactating after 6 months. The dietary vitamin D intake of 31 mothers was calculated. We found a significant correlation between the maternal serum 25-OHD concentration 16-18 weeks after delivery and the total vitamin D intake. The intake (5.5 micrograms/d, including supplementation) was lower than that recommended for lactating mothers which is 10 micrograms/d (Food and Nutrition Board, 1980).
PubMed ID
6088438 View in PubMed
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25-Hydroxyvitamin D levels during breast-feeding with or without maternal or infantile supplementation of vitamin D.

https://arctichealth.org/en/permalink/ahliterature238975
Source
J Pediatr Gastroenterol Nutr. 1985 Apr;4(2):220-6
Publication Type
Article
Date
Apr-1985
Author
M. Ala-Houhala
Source
J Pediatr Gastroenterol Nutr. 1985 Apr;4(2):220-6
Date
Apr-1985
Language
English
Publication Type
Article
Keywords
Adult
Alkaline Phosphatase - blood
Breast Feeding
Calcium - blood
Female
Finland
Humans
Hydroxycholecalciferols - blood
Infant
Magnesium - blood
Phosphorus - blood
Pilot Projects
Rickets - prevention & control
Risk
Seasons
Sunlight
Vitamin D - therapeutic use
Abstract
Serum 25-hydroxyvitamin D (25-OHD), calcium, phosphorus, magnesium, and alkaline phosphatase levels of breast-fed infants and their mothers were studied by following 100 healthy term mother-infant pairs with different supplementation protocols of vitamin D. A pilot study in winter revealed that six of eight breast-fed infants without vitamin D supplementation had serum 25-OHD levels below the risk limit for rickets (5 ng/ml) at the age of 8 weeks. In the main study in winter groups, it was found that the 25-OHD levels were low (5.6 +/- 3.7 ng/ml) at the age of 8 weeks in the unsupplemented breast-fed infants, whose mothers were given vitamin D supplementation of 1,000 IU/day during lactation (group I), compared with the levels of those infants receiving either 400 (18.0 +/- 8.4 ng/ml, group II) or 1,000 IU (22.8 +/- 11.2 ng/ml, group III) vitamin D (group I vs. group II or III, p less than 0.001; group II vs. group III, NS). In group I 10 of 18 infants had serum 25-OHD levels less than 5 ng/ml compared with none of the infants in groups II and III. Yet the infants with 25-OHD levels less than 5 ng/ml showed no signs of clinical or biochemical rickets at the age of 8 or 20 weeks. In summer at delivery the maternal 25-OHD levels were good, but decreased thereafter. Also in summer groups, the infantile 25-OHD concentrations decreased; however, because the levels at delivery were high, they stayed in the normal range.(ABSTRACT TRUNCATED AT 250 WORDS)
PubMed ID
3989622 View in PubMed
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Achievement of recommended treatment targets for bone and mineral metabolism in haemodialysis patients using paricalcitol: an observational study.

https://arctichealth.org/en/permalink/ahliterature136584
Source
Scand J Urol Nephrol. 2011 Apr;45(3):196-205
Publication Type
Article
Date
Apr-2011
Author
Anders Fernström
Jan Giæver
Barbara Granroth
Britta Hylander
Gert Jensen
Anders Christensson
Björn Wikström
Lars Weiss
Ulf Wrege
Stefan H Jacobson
Author Affiliation
Department of Nephrology, Linköping University/Linköping University Hospital, Linköping, Sweden. anders.fernstrom@lio.se
Source
Scand J Urol Nephrol. 2011 Apr;45(3):196-205
Date
Apr-2011
Language
English
Publication Type
Article
Keywords
Aged
Biomarkers, Pharmacological - blood - metabolism
Bone Density - drug effects
Bone Density Conservation Agents - administration & dosage - pharmacology - therapeutic use
Bone Diseases, Metabolic - drug therapy - etiology - metabolism
Bone and Bones - metabolism
Calcium - blood
Chronic Disease
Ergocalciferols - administration & dosage - pharmacology - therapeutic use
Female
Humans
Hyperparathyroidism, Secondary - complications - drug therapy - metabolism
Injections, Intravenous
Kidney Diseases - complications - metabolism - therapy
Male
Middle Aged
Observation
Parathyroid Hormone - metabolism
Phosphorus - blood
Prospective Studies
Renal Dialysis
Sweden
Abstract
Secondary hyperparathyroidism (SHPT) is a common problem among patients with chronic kidney disease (CKD) on haemodialysis. This study was conducted to assess the use, effectiveness and safety of intravenous paricalcitol in haemodialysis patients with various degrees of SHPT.
This observational, multicentre, prospective study was conducted in 14 Swedish dialysis centres from May 2007 to June 2008 and included 92 haemodialysis patients with a diagnosis of SHPT associated with CKD. The decision to initiate treatment with intravenous paricalcitol was made by the treating physician. No treatment algorithms were provided.
Mean patient age was 64 years. Of the 92 patients included, 74 had an intact parathyroid hormone (iPTH) level of >300 pg/ml at baseline. Median iPTH was 584 pg/ml in patients with a baseline PTH of >300 pg/ml. During follow-up there was a decrease in iPTH to 323 pg/ml at 6 months (-45%, p
PubMed ID
21366390 View in PubMed
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[ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT ELEVATION: POSSIBILITIES FOR PREDICTING THE CLINICAL COURSE AT THE POST-HOSPITAL (6 AND 12 MONTHS) STAGE].

https://arctichealth.org/en/permalink/ahliterature275680
Source
Klin Med (Mosk). 2016;94(3):205-10
Publication Type
Article
Date
2016
Source
Klin Med (Mosk). 2016;94(3):205-10
Date
2016
Language
Russian
Publication Type
Article
Keywords
Acute Coronary Syndrome - complications - diagnosis - metabolism - mortality
Aged
Calcium - blood
Creatinine - blood
Electrocardiography
Female
Follow-Up Studies
Humans
Interleukin-10 - blood
Interleukin-6 - blood
Male
Melatonin - analogs & derivatives - urine
Middle Aged
Myocardial Infarction - epidemiology - etiology
Potassium - blood
Predictive value of tests
Prognosis
Risk assessment
Russia - epidemiology
Sodium - metabolism
Abstract
To measure blood IL-6, IL-10, creatinine levels, calcium, sodium and potassium in blood and saliva, melatonin in urine of patients with acute coronary syndrome without ST segment elevation for the prediction of the clinical course at the post-hospital stage.
The study included 93 patients with complicated (n = 46) and uncomplicated (n = 47) coronary syndrome without ST segment elevation. Blood IL-6, IL-1, creatinine levels, calcium, sodium and potassium in blood and saliva, melatoni n in urine were determined on days 1-3 after hospitalization. 6-hydroxymelatonin was measured by HPLC in urine collected between 23 p.m. and 8 a.m., melatonin i in urine collected between 8 a.m. and 23 p.m.
Complicated coronary syndrome was associated with increased levels of melatonin (night), blood IL-10 and Na, salivary, Na and Ca while the uncomplicated condition with increased blood melatonin (daytime), IL-6, creatinine, Ca, Na, K, and salivary K. 90 patients were followed up within 12 months after discharge. End-points developed in 36 (40%) of them. Logistic analysis yielded variables and 2 logistic regression equations The data on night melatonin +5 and +4 were included in ROC analysis. The night melatonin +5 values over 0.7453 were associated with increased risk of complications in the post-hospital period (6 months) and values of 0.7453 or lower with the enhanced probability of uncomplicated clinical course. Prognostic sensitivity was estimated at 90%, specificity at -54.39%. The night melatonin +4 values over 0.2903 were associated with increased risk of complications in the post-hospital period (12 months) and values of 0.2903 or lower with the enhanced probability of uncomplicated clinical course. Prognostic sensitivity was estimated at 77.8%, specificity at -59.26%.
The night melatonin +5 and +4 models can be used to predict the clinical course of acute coronary syndrome during 6 and 12 months of the post-hospitalization period.
PubMed ID
27522726 View in PubMed
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Acute pancreatitis--30 years' experience at a teaching hospital.

https://arctichealth.org/en/permalink/ahliterature226629
Source
Can J Surg. 1991 Apr;34(2):137-43
Publication Type
Article
Date
Apr-1991
Author
E O Amurawaiye
R A Brown
Author Affiliation
Department of Surgery, Montreal General Hospital, McGill University, PQ.
Source
Can J Surg. 1991 Apr;34(2):137-43
Date
Apr-1991
Language
English
Publication Type
Article
Keywords
Acute Disease
Alcoholism - complications
Amylases - blood
Biliary Tract Diseases - complications
Calcium - blood
Cholangiopancreatography, Endoscopic Retrograde - adverse effects
Female
Humans
Male
Middle Aged
Pancreatitis - diagnosis - epidemiology - etiology - mortality - therapy
Quebec - epidemiology
Retrospective Studies
Survival Rate
Abstract
Advances in medical technology and knowledge have influenced morbidity and mortality in surgically treated diseases. The authors have compiled four consecutive retrospective studies of demography, morbidity and mortality of patients with acute pancreatitis to summarize the experience from 1956 to 1985 at the Montreal General Hospital with 629 patients. The death rate has remained unchanged. Hypotension, gastrointestinal bleeding and respiratory failure have assumed lesser roles as major complicating factors. Renal failure and gram-negative aerobic pancreatic sepsis are the common causes of death. The last two reviews revealed that surgical debridement and drainage combined with appropriate biliary procedures salvaged two-thirds of the patients with sepsis. Deteriorating nutritional status, heralded by a fall of serum albumin level below 30 g/L, is associated with a poor prognosis. Interval cholecystectomy in patients with mild biliary tract pancreatitis is associated with a low death rate (0.01%).
Notes
Comment In: Can J Surg. 1991 Apr;34(2):100-12025795
PubMed ID
1709060 View in PubMed
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An assessment of the risk of developing hyperparathyroidism and thyroid disorders subsequent to neck irradiation in middle-aged women.

https://arctichealth.org/en/permalink/ahliterature14625
Source
J Surg Oncol. 1985 Jun;29(2):78-81
Publication Type
Article
Date
Jun-1985
Author
I. Hedman
M. Fjälling
S. Lindberg
L M Lundberg
L E Tisell
Source
J Surg Oncol. 1985 Jun;29(2):78-81
Date
Jun-1985
Language
English
Publication Type
Article
Keywords
Aged
Calcium - blood
Cervical Vertebrae
Female
Follow-Up Studies
Humans
Hyperparathyroidism - blood - etiology
Middle Aged
Neck
Radiotherapy - adverse effects
Radiotherapy Dosage
Research Support, Non-U.S. Gov't
Risk
Spinal Osteophytosis - radiotherapy
Sweden
Thyroid Diseases - etiology
Time Factors
Abstract
We investigated the occurrence of thyroid and parathyroid disorders in 100 women (age 66-70 years) irradiated for cervical spondylosis on average 25 years previously and in 100 control women of similar age. Hyperparathyroidism (HPT), proven by operation, was diagnosed in one patient of each group, and three additional cases were diagnosed biochemically among irradiated women. The difference in incidence is not significant. Nor was there any significant difference in incidence of thyroid disorders. No thyroid carcinoma was found in either group. Even if there is a moderate increase of HPT after neck irradiation in middle-aged women the risk is not so great as to warrant organised follow-up.
PubMed ID
4079389 View in PubMed
Less detail

[Anomalies of phospho-calcium metabolism during antiepileptic treatment]

https://arctichealth.org/en/permalink/ahliterature40032
Source
Pediatr Med Chir. 1983 Nov-Dec;5(6):571-3
Publication Type
Article
Author
C. Marchesoni
P. De Marco
G F Ronconi
P G Miottello
Source
Pediatr Med Chir. 1983 Nov-Dec;5(6):571-3
Language
Italian
Publication Type
Article
Keywords
Adolescent
Alkaline Phosphatase - blood
Anticonvulsants - adverse effects
Calcium - blood - metabolism
Child
Child, Preschool
Drug Therapy, Combination
English Abstract
Ergocalciferols - therapeutic use
Humans
Infant
Phenobarbital - administration & dosage - adverse effects
Phenytoin - administration & dosage - adverse effects
Phosphorus - blood - metabolism
Rickets - chemically induced - prevention & control
Abstract
It is known that, particularly in Nordic States, many patients undergoing antiepileptic therapy with Phenobarbital and Phentoin present disorders of the phospho-calcium metabolism, both clinical and biochemical. For what concerns the mediterranean area, few are the papers written concerning this subject in these last years. In this paper we attempt to provide a "case study" contribution (100 cases) to enable us to study the above-mentioned alteration focusing on an area half way between Central and Southern Europe. The Authors discuss the possible mechanism implicated in this affection.
PubMed ID
6335748 View in PubMed
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Are CSN and NKF-K/DOQI mineral metabolism guidelines for hemodialysis patients achievable? Results from a provincial renal program.

https://arctichealth.org/en/permalink/ahliterature155898
Source
CANNT J. 2008 Apr-Jun;18(2):36-41, 44-50; quiz 42-3, 51-2
Publication Type
Article
Author
Lori D Wazny
Colette B Raymond
Esther M Lesperance
Keevin N Bernstein
Author Affiliation
Department of Pharmaceutical Services, Health Sciences Centre, Winnipeg, MB. Lwazny@hsc.mb.ca
Source
CANNT J. 2008 Apr-Jun;18(2):36-41, 44-50; quiz 42-3, 51-2
Language
English
French
Publication Type
Article
Keywords
Aged
Calcium - blood
Cross-Sectional Studies
Drug Utilization
Female
Guideline Adherence - standards
Hemodialysis Solutions - therapeutic use
Humans
Kidney Failure, Chronic - etiology - metabolism - therapy
Male
Manitoba
Medical Audit
Middle Aged
Monitoring, Physiologic
Outcome Assessment (Health Care)
Parathyroid Hormone - blood
Phosphorus - blood
Practice Guidelines as Topic
Quality Indicators, Health Care
Renal Dialysis - methods - standards
Serum Albumin - metabolism
Treatment Outcome
Abstract
The calcium, phosphorus, and parathyroid hormone targets recommended by the Canadian Society of Nephrology (CSN) encompass a wider range of values as compared to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (NKF-K/DOQI) guidelines. We sought to compare mineral metabolism parameters within the Manitoba Renal Program (MRP) to the CSN and NKF-K/DOQI guidelines. Medication use was also examined.
All hemodialysis patients in Manitoba were evaluated. Values for serum albumin, phosphorus, calcium, intact parathyroid hormone (PTH) and pertinent medications were collected.
Five hundred and forty-six patients were included in the analysis. Fifty-three per cent to 81% of MRP patients met individual CSN targets. However, only 26% of patients achieved all targets, despite high usage of phosphate (85.5% calcium carbonate, 16.1% sevelamer, 1.3% aluminum) and PTH-lowering drug therapies (30.2% calcitriol, 2.7% cinacalcet).
Only a small proportion of patients were able to achieve all three CSN mineral metabolism targets simultaneously. The majority of outliers presented with hyperphosphatemia or hypoparathyroidism.
PubMed ID
18669010 View in PubMed
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199 records – page 1 of 20.