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1H MRS studies in the Finnish boron neutron capture therapy project: detection of 10B-carrier, L-p-boronophenylalanine-fructose.

https://arctichealth.org/en/permalink/ahliterature172386
Source
Eur J Radiol. 2005 Nov;56(2):154-9
Publication Type
Article
Date
Nov-2005
Author
M. Timonen
L. Kankaanranta
N. Lundbom
J. Collan
A. Kangasmäki
M. Kortesniemi
A-M Häkkinen
A. Lönngren
S. Karjalainen
M. Rasilainen
J. Leinonen
T. Huitti
J. Jääskeläinen
M. Kouri
S. Savolainen
S. Heikkinen
Author Affiliation
Department of Physical Sciences, University of Helsinki, POB 64, FIN-00014, Helsinki, Finland.
Source
Eur J Radiol. 2005 Nov;56(2):154-9
Date
Nov-2005
Language
English
Publication Type
Article
Keywords
Adult
Aged
Boron - therapeutic use
Boron Compounds - analysis - blood
Boron Neutron Capture Therapy
Brain Neoplasms - pathology - radiotherapy
Carcinoma - pathology - radiotherapy
Female
Finland
Fructose - analogs & derivatives - analysis - blood
Glioblastoma - pathology - radiotherapy
Humans
Hydrogen
Isotopes - therapeutic use
Magnetic Resonance Spectroscopy - methods
Male
Neoplasm Recurrence, Local - pathology - radiotherapy
Paranasal Sinus Neoplasms - pathology - radiotherapy
Phantoms, Imaging
Plasma
Radiopharmaceuticals - therapeutic use
Abstract
This article summarizes the current status of 1H MRS in detecting and quantifying a boron neutron capture therapy (BNCT) boron carrier, L-p-boronophenylalanine-fructose (BPA-F) in vivo in the Finnish BNCT project. The applicability of 1H MRS to detect BPA-F is evaluated and discussed in a typical situation with a blood containing resection cavity within the gross tumour volume (GTV). 1H MRS is not an ideal method to study BPA concentration in GTV with blood in recent resection cavity. For an optimal identification of BPA signals in the in vivo 1H MR spectrum, both pre- and post-infusion 1H MRS should be performed. The post-infusion spectroscopy studies should be scheduled either prior to or, less optimally, immediately after the BNCT. The pre-BNCT MRS is necessary in order to utilise the MRS results in the actual dose planning.
PubMed ID
16233888 View in PubMed
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[The characteristics of using mineral waters with an increased boron content in rehabilitating patients with hepatobiliary pathology]

https://arctichealth.org/en/permalink/ahliterature73624
Source
Vopr Kurortol Fizioter Lech Fiz Kult. 1991 May-Jun;(3):38-41
Publication Type
Article
Author
V I Shman'ko
V A Cherleniak
M I Zavadiak
O N Ganich
Source
Vopr Kurortol Fizioter Lech Fiz Kult. 1991 May-Jun;(3):38-41
Language
Russian
Publication Type
Article
Keywords
Adult
Bile - chemistry - drug effects - secretion
Boron - therapeutic use
Cholecystitis - physiopathology - rehabilitation
Chronic Disease
Comparative Study
English Abstract
Female
Health Resorts
Humans
Male
Mineral Waters
Ukraine
Abstract
Changes in biochemical bile composition were investigated in 42 patients with chronic infective acalculous cholecystitis on combined sanatorium treatment. In those with carbohydrate dysbolism, bile production was found inhibited possibly due to the intake of carbonate sodium mineral water of moderate mineralization containing bromine and fluorine with high concentrations of bromine, in particular.
PubMed ID
1926799 View in PubMed
Less detail