There is accumulating evidence that gestational diabetes is a growing problem. The lack of internationally standardized diagnostic procedures prevents consistent diagnosis and the burden of gestational diabetes must be determined in country-specific studies. In southern Sweden, gestational diabetes is defined as a 2-h capillary plasma glucose concentration of =10.0 mmol/L during a universal 75-g oral glucose tolerance test. We report the crude prevalence of gestational diabetes during the years 2003-2012. Of 156 144 women who gave birth, 2.2% were diagnosed with gestational diabetes. When the effect of time on the prevalence of gestational diabetes was assessed in a log-linear Poisson model, an overall increase in prevalence of 35% was predicted, corresponding to an average annual increase of 3.4%. Predicted prevalence was 1.9 (95% CI 1.8-2.0) in 2003 and 2.6 (95% CI 2.4-2.7) in 2012 (p
Correlation analysis of the findings suggests that in March an increase of the glucose level is induced by the thyroid hormones in humans living on Spitsbergen Archipelago. A liability of functional interactions among thyroid hormones, insulin, and glucose seems to be caused bias alterations in the air temperature as contrast to photoperiodicity.
In a pilot study in patients with verified peripheral arterial occlusion, smoking was compared with hypertension, hyperlipidemia, and glucose intolerance, as a risk factor for peripheral arterial disease. The material consists of 17 men, all new out-patients at the Department of Surgery in Malmö during the first 6 months of 1973. Of these patients, 15 were smokers, all inhaled. Glucose intolerance was found in 4, hyperlipidemia in 3 and hypertension in 2 individuals. It is shown that smoking, glucose intolerance, hyperlipidemia and hypertension are more common in patients with peripheral arterial disease than in defined population groups. In patients with bilateral occlusion an increased number of risk factors was found. Smoking was the most common risk factor and in 10 patients it was the only known risk factor.