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568 records – page 1 of 57.

[3 cases of viral carriage detected during screening for HIV antibodies].

https://arctichealth.org/en/permalink/ahliterature226768
Source
Zh Mikrobiol Epidemiol Immunobiol. 1991 Mar;(3):16-8
Publication Type
Article
Date
Mar-1991
Author
E M Shelukhina
E V Chekunova
G R Matsevich
I A Okunev
S S Marennikova
M R Zak
Source
Zh Mikrobiol Epidemiol Immunobiol. 1991 Mar;(3):16-8
Date
Mar-1991
Language
Russian
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - epidemiology - immunology - prevention & control
Blood Donors
Carrier State - epidemiology - immunology - prevention & control
Enzyme-Linked Immunosorbent Assay
HIV Antibodies - blood
HIV Seropositivity - epidemiology - immunology
HIV-1 - immunology
Humans
Immunoblotting
Lithuania - epidemiology
Mass Screening - methods
Moscow - epidemiology
Risk factors
Abstract
The results of screening more than 23,000 serum samples from persons belonging to risk groups, as well as those not belonging to such groups, in Moscow, Vilnius and Klaipeda are presented. Screening was carried out with the use of an assay system manufactured by the Scientific and Industrial Amalgamation "Antigen" (USSR). In this screening 3 HIV carriers were detected; of these, 2 were foreign students from two African countries.
PubMed ID
1872091 View in PubMed
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ABH secretor status, as judged by the Lewis phenotypes, in Norwegian survivors from meningococcal disease.

https://arctichealth.org/en/permalink/ahliterature220181
Source
APMIS. 1993 Oct;101(10):791-4
Publication Type
Article
Date
Oct-1993
Author
L. Kornstad
A L Heistøo
T E Michaelsen
G. Bjune
Author Affiliation
National Institute of Public Health, Oslo, Norway.
Source
APMIS. 1993 Oct;101(10):791-4
Date
Oct-1993
Language
English
Publication Type
Article
Keywords
ABO Blood-Group System - blood
Adolescent
Adult
Blood Donors
Disease Susceptibility
Fucosyltransferases - genetics
Humans
Lewis Blood-Group System - blood
Meningococcal Infections - blood - physiopathology
Neisseria meningitidis - classification
Norway
Phenotype
Reference Values
Serotyping
Abstract
Survivors from meningococcal disease (serogroups B and C) and a control series (blood donors) were examined for their ability to secrete ABH blood group substance. The examination was done indirectly by determining their Lewis phenotypes. There was no significant difference in the secretor status between the two groups.
PubMed ID
8267956 View in PubMed
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Abnormal alanine aminotransferase level in blood units from donors in Montreal does not indicate high risk of transmitting hepatitis.

https://arctichealth.org/en/permalink/ahliterature242404
Source
Clin Invest Med. 1983;6(4):327-30
Publication Type
Article
Date
1983
Author
U P Steinbrecher
T O Kovacs
A. Gelly
M. Tourigny
Source
Clin Invest Med. 1983;6(4):327-30
Date
1983
Language
English
Publication Type
Article
Keywords
Alanine Transaminase - blood
Blood Donors
Blood Transfusion - adverse effects
Hepatitis, Viral, Human - transmission
Humans
Quebec
Risk
Abstract
We undertook a prospective study to estimate the risk in Montreal of developing hepatitis following transfusion of blood with an elevated alanine aminotransferase (ALT) level. Two thousand consecutive donor units were screened for ALT activity; 133 (6.7%) had values greater than or equal to 51 IU 1(-1). Twenty-four patients received one or more units with elevated ALT levels and completed follow-up; two (8%) developed hepatitis (one of these was type B hepatitis). One of the 10 'control' patients who received only units with normal ALT levels also developed hepatitis. In this study, the risk of transfusion-transmitted hepatitis was the same in recipients of blood units with abnormal ALT levels as in those who received only blood with normal ALT, and very similar to the risk reported in other studies for recipients of volunteer donor blood with normal ALT. These findings require confirmation by a larger study, but suggest that the hepatitis risk associated with transfusion of high-ALT blood may be lower in Montreal than has been reported in several centers in the U.S.
PubMed ID
6671363 View in PubMed
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ABO Blood Group and Risk of Thromboembolic and Arterial Disease: A Study of 1.5 Million Blood Donors.

https://arctichealth.org/en/permalink/ahliterature275912
Source
Circulation. 2016 Apr 12;133(15):1449-57; discussion 1457
Publication Type
Article
Date
Apr-12-2016
Author
Senthil K Vasan
Klaus Rostgaard
Ammar Majeed
Henrik Ullum
Kjell-Einar Titlestad
Ole B V Pedersen
Christian Erikstrup
Kaspar Rene Nielsen
Mads Melbye
Olof Nyrén
Henrik Hjalgrim
Gustaf Edgren
Source
Circulation. 2016 Apr 12;133(15):1449-57; discussion 1457
Date
Apr-12-2016
Language
English
Publication Type
Article
Keywords
ABO Blood-Group System - analysis - genetics
Adult
Arterial Occlusive Diseases - epidemiology - genetics
Blood Donors - statistics & numerical data
Denmark - epidemiology
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Pregnancy
Pregnancy Complications, Cardiovascular - epidemiology - genetics
Pulmonary Embolism - epidemiology - genetics
Recurrence
Regression Analysis
Risk
Sweden - epidemiology
Thromboembolism - epidemiology - genetics
Thrombophilia - genetics
Venous Thrombosis - epidemiology - genetics
Young Adult
Abstract
ABO blood groups have been shown to be associated with increased risks of venous thromboembolic and arterial disease. However, the reported magnitude of this association is inconsistent and is based on evidence from small-scale studies.
We used the SCANDAT2 (Scandinavian Donations and Transfusions) database of blood donors linked with other nationwide health data registers to investigate the association between ABO blood groups and the incidence of first and recurrent venous thromboembolic and arterial events. Blood donors in Denmark and Sweden between 1987 and 2012 were followed up for diagnosis of thromboembolism and arterial events. Poisson regression models were used to estimate incidence rate ratios as measures of relative risk. A total of 9170 venous and 24 653 arterial events occurred in 1 112 072 individuals during 13.6 million person-years of follow-up. Compared with blood group O, non-O blood groups were associated with higher incidence of both venous and arterial thromboembolic events. The highest rate ratios were observed for pregnancy-related venous thromboembolism (incidence rate ratio, 2.22; 95% confidence interval, 1.77-2.79), deep vein thrombosis (incidence rate ratio, 1.92; 95% confidence interval, 1.80-2.05), and pulmonary embolism (incidence rate ratio, 1.80; 95% confidence interval, 1.71-1.88).
In this healthy population of blood donors, non-O blood groups explain >30% of venous thromboembolic events. Although ABO blood groups may potentially be used with available prediction systems for identifying at-risk individuals, its clinical utility requires further comparison with other risk markers.
PubMed ID
26939588 View in PubMed
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Absence of human T-lymphotropic virus types I and II infection in an Ontario hemophilia population.

https://arctichealth.org/en/permalink/ahliterature223481
Source
Transfusion. 1992 Jul-Aug;32(6):513-6
Publication Type
Article
Author
G. Dekaban
M. Inwood
D. Waters
J. Drouin
J. Teitel
Author Affiliation
Immunology Group, John Roberts Research Institute, University of Western Ontario, London, Canada.
Source
Transfusion. 1992 Jul-Aug;32(6):513-6
Language
English
Publication Type
Article
Keywords
Adult
Blood Donors
Blotting, Western
DNA, Viral - analysis
HIV Seropositivity - blood
HTLV-I Infections - blood
HTLV-II Infections - blood
Hemophilia A - blood - microbiology
Humans
Ontario
Polymerase Chain Reaction
Retrospective Studies
Abstract
Two hundred ninety-three serum samples from Ontario hemophiliacs and 200 samples from human immunodeficiency virus-positive blood donors were screened for the presence of antibodies to human T-lymphotropic virus type I (HTLV-I) by enzyme-linked immunosorbent assay, radioimmunoassay, and Western blot techniques. None of the serum samples provided unequivocal positive results, but several samples gave inconclusive results. Of the hemophiliacs with inconclusive serologic results from whom peripheral blood lymphocyte DNA could be obtained, all were negative for HTLV-I and HTLV type II (HTLV-II) sequences as determined by polymerase chain reaction (PCR). PCR was also performed on a lymph node biopsy sample taken from a hemophiliac who developed a rare T-cell lymphoma; the sample was negative for HTLV-I and -II sequences. These results indicate that Ontario hemophiliacs have not been exposed to HTLV-I or HTLV-II.
PubMed ID
1502703 View in PubMed
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Absence of indigenous specific West Nile virus antibodies in Tyrolean blood donors.

https://arctichealth.org/en/permalink/ahliterature134646
Source
Eur J Clin Microbiol Infect Dis. 2012 Jan;31(1):77-81
Publication Type
Article
Date
Jan-2012
Author
S T Sonnleitner
J. Simeoni
E. Schmutzhard
M. Niedrig
F. Ploner
H. Schennach
M P Dierich
G. Walder
Author Affiliation
Hygiene and Medical Microbiology, Medical University Innsbruck, Fritz Pregl Straße 1-3/III, Innsbruck, Austria. sissyson@gmx.at
Source
Eur J Clin Microbiol Infect Dis. 2012 Jan;31(1):77-81
Date
Jan-2012
Language
English
Publication Type
Article
Keywords
Adult
Antibodies, Viral - blood
Blood Donors
Child, Preschool
Encephalitis Viruses, Tick-Borne - immunology
Enzyme-Linked Immunosorbent Assay
Europe
False Positive Reactions
Female
Humans
Italy
Male
Middle Aged
Neutralization Tests
West Nile Fever - diagnosis - epidemiology - virology
West Nile virus - immunology
Abstract
In the last several years, West Nile virus (WNV) was proven to be present especially in the neighboring countries of Austria, such as Italy, Hungary, and the Czech Republic, as well as in eastern parts of Austria, where it was detected in migratory and domestic birds. In summer 2010, infections with WNV were reported from Romania and northern Greece with about 150 diseased and increasingly fatal cases. We tested the sera of 1,607 blood donors from North Tyrol (Austria) and South Tyrol (Italy) for antibodies against WNV by using IgG enzyme-linked immunosorbent assay (ELISA). Initial results of the ELISA tests showed seroprevalence rates of 46.2% in North Tyrol and 0.5% in South Tyrol, which turned out to be false-positive cross-reactions with antibodies against tick-borne encephalitis virus (TBEV) by adjacent neutralization assays. These results indicate that seropositivity against WNV requires confirmation by neutralization assays, as cross-reactivity with TBEV is frequent and because, currently, WNV is not endemic in the study area.
PubMed ID
21556676 View in PubMed
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Adverse reactions in healthy blood donors undergoing plasmapheresis.

https://arctichealth.org/en/permalink/ahliterature103390
Source
Prog Clin Biol Res. 1990;337:485-6
Publication Type
Article
Date
1990
Author
M L Schroeder
N. Buskard
M. Herbert
J. Kelton
G. Rock
M. Sternbach
Author Affiliation
Centre of the Canadian Red Cross Blood Transfusion Service.
Source
Prog Clin Biol Res. 1990;337:485-6
Date
1990
Language
English
Publication Type
Article
Keywords
Blood Donors
Canada
Humans
Plasmapheresis - adverse effects - instrumentation
Safety
PubMed ID
2353009 View in PubMed
Less detail

Age-dependent increase of Campylobacter pylori antibodies in blood donors.

https://arctichealth.org/en/permalink/ahliterature231679
Source
Scand J Gastroenterol. 1989 Jan;24(1):110-4
Publication Type
Article
Date
Jan-1989
Author
T U Kosunen
J. Höök
H I Rautelin
G. Myllylä
Author Affiliation
Dept. of Bacteriology and Immunology, University of Helsinki, Finland.
Source
Scand J Gastroenterol. 1989 Jan;24(1):110-4
Date
Jan-1989
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Aged
Antibodies, Bacterial - analysis
Blood Donors
Campylobacter - immunology
Female
Finland
Humans
Immunoenzyme Techniques
Male
Middle Aged
Abstract
Antibodies against Campylobacter pylori were determined in 500 blood donors aged 18 to 65 years. Acid extract from a C. pylori strain was used as antigen in enzyme immunoassay. The proportion of donors with high antibody titers increased with age. For IgG antibodies it was 10% in the age group from 18 to 25 years but 60% in the group from 56 to 65 years; the increase for IgA and IgM antibodies was from 5 to 42% and from 7 to 21%, respectively. The geometric mean titers of those with high values showed no clear changes with age, which would imply chronic antigenic stimulus.
PubMed ID
2648556 View in PubMed
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[A genetic pool study of the population of the Republic of Tyva using genetic markers for the search for associations with tuberculosis]

https://arctichealth.org/en/permalink/ahliterature69550
Source
Probl Tuberk. 1996;(4):38-41
Publication Type
Article
Date
1996
Author
L E Pospelov
A G Matrakshin
K N Tsoi
L S Erdynieva
B K Kuderek
Source
Probl Tuberk. 1996;(4):38-41
Date
1996
Language
Russian
Publication Type
Article
Keywords
Blood Donors
Blood Proteins - genetics
Chi-Square Distribution
Comparative Study
Electrophoresis, Polyacrylamide Gel - statistics & numerical data
English Abstract
Gene Pool
Genetic markers
Genotype
HLA Antigens - genetics
Humans
Reference Values
Risk factors
Siberia
Tuberculosis, Pulmonary - genetics
Abstract
Eighty three Tyvin patients with local pulmonary tuberculosis and 295 healthy donors of the same nationality were examined. They are resided in the central area of Tyva (in Kyzyl and its vicinities). In addition, 132 healthy Tyvin-Todjins were examined. Tuberculosis mortality was found to be associated with the antigen HLA-B15 in the Tyvins living in the central area of the Republic of Tyva (Kyzyl). The incidence of HLA antigens and polymorphic protein locus genotypes varies in different areas of the Republic of Tyva.
PubMed ID
9026803 View in PubMed
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The aging population poses a global challenge for blood services.

https://arctichealth.org/en/permalink/ahliterature147386
Source
Transfusion. 2010 Mar;50(3):584-8
Publication Type
Article
Date
Mar-2010
Author
Akif Ali
Marja-Kaisa Auvinen
Jukka Rautonen
Author Affiliation
Finnish Red Cross Blood Service, Helsinki, Finland.
Source
Transfusion. 2010 Mar;50(3):584-8
Date
Mar-2010
Language
English
Publication Type
Article
Keywords
Adult
Age Factors
Aged
Aged, 80 and over
Blood Donors - supply & distribution
Erythrocyte Transfusion
Female
Finland
Humans
Male
Medical Records Systems, Computerized
Middle Aged
Population Dynamics
Registries
Abstract
The Finnish transfusion registry data suggest some alarming signals and future challenges that are likely to be faced by transfusion services as populations continue to age.
Computerized data collection was performed on all potentially transfused patients in Finland, thus covering approximately 70% of all blood usage. We simulated the red blood cell (RBC) usage according to the Finnish practice on different age groups but the population demographics from other countries.
The Finnish data demonstrate a marked increase in RBC consumption with increasing age among recipients, beginning at around 50 years of age. The 70- to 80-year-olds have an eightfold higher RBC consumption than 20- to 40-year-olds.
A large part of the variation in RBC use per capita can be explained by the age distribution of the different populations and not by the different national and regional treatment policies and protocols used. If current efforts are not enough to serve the changing population demographic and if increasing demands for blood products cannot be met, there is need to consider unprecedented measures such as reversing certain donor deferrals or even exporting blood from country to country.
PubMed ID
19912582 View in PubMed
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568 records – page 1 of 57.