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Bladder cancer in the aluminium industry.

https://arctichealth.org/en/permalink/ahliterature240592
Source
Lancet. 1984 Apr 28;1(8383):947-50
Publication Type
Article
Date
Apr-28-1984
Author
G. Thériault
C. Tremblay
S. Cordier
S. Gingras
Source
Lancet. 1984 Apr 28;1(8383):947-50
Date
Apr-28-1984
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aluminum - poisoning
Benzopyrenes - poisoning
Carcinoma, Basal Cell - chemically induced - epidemiology
Humans
Male
Middle Aged
Occupational Diseases - chemically induced - epidemiology
Occupations
Quebec
Risk
Smoking
Urinary Bladder Neoplasms - chemically induced - epidemiology
Abstract
The incidence of bladder cancer is unusually high in aluminium smelter workers. An epidemiological study showed that workers in Soderberg potrooms are at highest risk for bladder cancer, the adjusted overall relative risk being 2.39 (1.34-4.28). Exposure to polycyclic aromatic hydrocarbons, of which benz(a)pyrene (BaP) served as an indicator, seems to be the causative factor. The relative risk was evaluated at 12.38 for workers with 20 or more equivalent years of BaP exposure. Cigarette smoking contributed significantly to the appearance of bladder cancer in the population studied. There is a synergistic effect when cigarette smoking and BaP exposure are combined; the numbers in our population are too small to determine whether this interaction effect is multiplicative or additive. It is concluded that bladder cancer is associated with aluminium smelting (primarily with the Soderberg process).
PubMed ID
6143877 View in PubMed
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Diesel exhaust - an occupational carcinogen?

https://arctichealth.org/en/permalink/ahliterature246534
Source
J Occup Med. 1980 Jan;22(1):41-6
Publication Type
Article
Date
Jan-1980
Author
M B Schenker
Source
J Occup Med. 1980 Jan;22(1):41-6
Date
Jan-1980
Language
English
Publication Type
Article
Keywords
Benzopyrenes - poisoning
Carcinogens, Environmental
Finland
Fuel Oils
Humans
London
Lung Neoplasms - epidemiology - etiology
Mining
Occupational Diseases - etiology
Petroleum
Polycyclic Compounds - poisoning
Railroads
United States
Vehicle Emissions - poisoning
Abstract
The existence of polycyclic aromatic hydrocarbons (PAH) in the particulate phase of diesel engine exhaust has raised concern about a carcinogenic effect in workers exposed to exhaust from diesel engines. Some of the PAH are carcinogenic following inhalation by experimental animals and are associated with excess cancer mortality in some occupational exposures. Studies of occupational exposure to diesel exhaust show concentrations of PAH are above ambient levels but below the very high levels in occupations with demonstrated excess cancer mortality. A critical review of the epidemiologic evidence on the carcinogenicity of workplace exposure to diesel engine exhaust is suggestive of a carcinogenic effect but the existing data are sparse and contradictory. Further epidemiologic studies of this question are needed.
PubMed ID
6153403 View in PubMed
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[The problem of radon--lung cancer, diesel vehicles in underground work and benzopyrene pollution]

https://arctichealth.org/en/permalink/ahliterature28064
Source
Lakartidningen. 1974 Oct 30;71(44):4328-30
Publication Type
Article
Date
Oct-30-1974